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The New England Journal of Medicine, ISSN 0028-4793, 08/2016, Volume 375, Issue 7, pp. 631 - 643
In this 12-month, placebo-controlled trial involving patients with primary biliary cholangitis who had an inadequate response to ursodiol, treatment with... 
CHANGING NOMENCLATURE | PBC | FXR | MEDICINE, GENERAL & INTERNAL | URSODEOXYCHOLIC ACID | PROGNOSIS | CIRRHOSIS | CHOLESTATIC PRURITUS | NONALCOHOLIC STEATOHEPATITIS | BIOCHEMICAL RESPONSE | SCALE | Liver Cirrhosis - etiology | Bile Acids and Salts - blood | Double-Blind Method | Humans | Middle Aged | Liver Cirrhosis, Biliary - drug therapy | Male | Chenodeoxycholic Acid - analogs & derivatives | Bone Density - drug effects | Chenodeoxycholic Acid - adverse effects | Fibroblast Growth Factors - blood | Chenodeoxycholic Acid - therapeutic use | Adult | Female | Aged | Liver Cirrhosis, Biliary - complications | Liver Cirrhosis, Biliary - blood | Alkaline Phosphatase - blood | Pruritus - chemically induced | Clinical trials | Ursodiol | Care and treatment | Usage | Dosage and administration | Cholangitis | Primary biliary cirrhosis | Alkaline phosphatase | Liver diseases | Syngeneic grafts | Liver | Bilirubin | Pruritus | Phosphatase | Patients | Cirrhosis | Allografts | Acids | Fibrosis | Drug therapy | Bile | Liver transplantation | Index Medicus | Abridged Index Medicus | Alkaline Phosphatase | Chenodeoxycholic Acid | Fibroblast Growth Factors | Gastroenterology and Hepatology | Bone Density | drug therapy | chemically induced | complications | Gastroenterologi | drug effects | Liver Cirrhosis | blood | Bile Acids and Salts | etiology | Biliary | analogs & derivatives | adverse effects | therapeutic use
Journal Article
Hepatology, ISSN 0270-9139, 04/2013, Volume 57, Issue 4, pp. 1394 - 1406
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 01/2017, Volume 58, Issue 1, pp. 267 - 278
As neurons die, cholesterol is released in the central nervous system (CNS); hence, this sterol and its metabolites may represent a biomarker of... 
Cytochrome p450 | Brain lipids | Cholestenoic acids | Nuclear receptors/lxr | Oxysterols | Mass spectrometry | Neurodeneneration | Bile acids and salts/biosynthesis | cholestenoic acids | brain lipids | HOMEOSTASIS | bile acids and salts/biosynthesis | LIVER-X RECEPTORS | oxysterols | nuclear receptors/LXR | BIOCHEMISTRY & MOLECULAR BIOLOGY | cytochrome P450 | CEREBROSPINAL-FLUID | BLOOD-BRAIN-BARRIER | MASS-SPECTROMETRY | neurodeneneration | PLASMA | CELL-MIGRATION | NEURONS | 27-HYDROXYCHOLESTEROL | mass spectrometry | Neurons - pathology | Bile Acids and Salts - blood | Central Nervous System - metabolism | Cholesterol - blood | Cholesterol - isolation & purification | Humans | Middle Aged | Central Nervous System - pathology | Male | Amyotrophic Lateral Sclerosis - blood | Bile Acids and Salts - cerebrospinal fluid | Nerve Degeneration - pathology | Nerve Degeneration - cerebrospinal fluid | Lipids - isolation & purification | Amyotrophic Lateral Sclerosis - pathology | Lipids - cerebrospinal fluid | Nerve Degeneration - blood | Amyotrophic Lateral Sclerosis - cerebrospinal fluid | Bile Acids and Salts - isolation & purification | Lipids - blood | Female | Aged | Neurons - metabolism | Cholesterol - cerebrospinal fluid | Neuroprotection | Acids | Metabolites | Sterols | Neurodegeneration | Central nervous system | Amyotrophic lateral sclerosis | Lipid metabolism | Cerebrospinal fluid | Cholesterol | Sclerosis | Bile | Index Medicus | nuclear receptors | Patient-Oriented and Epidemiological Research | LXR | biosynthesis | bile acids and salts
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 60, Issue 4, pp. 824 - 831
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue Supplement 1, pp. 4523 - 4530
Journal Article
Analytica Chimica Acta, ISSN 0003-2670, 12/2018, Volume 1037, pp. 245 - 255
A liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI(+)-MS/MS) assay was developed and qualified for analyzing 35 analytes of the... 
Validation | Free oxysterols | Footnote | LIFE-Adult | Pre-analytics | Targeted metabolomics | Free bile acids | APP/PS1 MICE | CHEMISTRY, ANALYTICAL | OXIDATIVE MECHANISM | ALZHEIMERS-DISEASE | 3-NITROPROPIONIC ACID | BLOOD-BRAIN-BARRIER | TAUROURSODEOXYCHOLIC ACID | CHOLESTEROL-METABOLISM | 7-ALPHA-HYDROXY-3-OXO-4-CHOLESTENOIC ACID | URSODEOXYCHOLIC ACID | HUNTINGTONS-DISEASE | Tandem Mass Spectrometry | Bile Acids and Salts - blood | Humans | Bile Acids and Salts - chemistry | Oxysterols - chemistry | Solid Phase Extraction | Chromatography, Liquid | Oxysterols - blood | Bile Acids and Salts - metabolism | Bile Acids and Salts - cerebrospinal fluid | Oxysterols - metabolism | Oxysterols - cerebrospinal fluid | Liquid chromatography | Precipitation (Meteorology) | Metabolites | Mass spectrometry | Analysis | Deoxycholic acid | Deuterium | Plasma | Additives | Lithium | Cerebrospinal fluid | Cholic acid | Ursodeoxycholic acid | Blood plasma | Proteins | Sample preparation | Blood-brain barrier | Ethylenediaminetetraacetic acids | Disturbance | Lipid metabolism | Solid phases | Stability tests | Spectroscopy | Taurocholic acid | Anticoagulants | Bile acids | Chemical precipitation | Mass spectroscopy | Stability analysis | Metabolism | Patients | Cholesterol | Esterification | Citric acid | Acids | Ionization | Heparin | Chenodeoxycholic acid | Edetic acid | Bile | Index Medicus
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 03/2015, Volume 283, Issue 3, pp. 168 - 177