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1985, ISBN 0444806709, Volume 12., xv, 447
Book
Cell Metabolism, ISSN 1550-4131, 02/2013, Volume 17, Issue 2, pp. 225 - 235
Bile acids are synthesized from cholesterol in the liver and further metabolized by the gut microbiota into secondary bile acids. Bile acid synthesis is under... 
ACTIVATION | DISRUPTION | STEROIDS | LIVER | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | FARNESOID-X-RECEPTOR | GERM-FREE | ABSORPTION | DIFFERENTIAL REGULATION | BINDING | CELL BIOLOGY | Organ Specificity - drug effects | Taurocholic Acid - metabolism | Fibroblast Growth Factors - genetics | Ileum - metabolism | Gene Expression Profiling | Fibroblast Growth Factors - metabolism | Organ Specificity - genetics | Ileum - drug effects | Metagenome - genetics | Absorption | Liver - drug effects | Taurocholic Acid - analogs & derivatives | Taurocholic Acid - pharmacology | Metagenome - drug effects | Liver - metabolism | Gastrointestinal Tract - microbiology | Bile Acids and Salts - metabolism | Gastrointestinal Tract - drug effects | Gene Expression Regulation - drug effects | Cholesterol 7-alpha-Hydroxylase - genetics | Animals | Cholesterol 7-alpha-Hydroxylase - metabolism | Models, Biological | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Feedback, Physiological - drug effects | Anti-Bacterial Agents - pharmacology | Mice | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Fibroblast growth factors | Universities and colleges | Cytochrome P-450 | Deoxycholic acid | Index Medicus | Biological Sciences | Clinical Medicine | Naturvetenskap | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Biologiska vetenskaper | Natural Sciences | Cellbiologi | Klinisk medicin | Cell Biology | Endocrinology and Diabetes
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7533, pp. 205 - 208
Journal Article
1986, ISBN 9780881672435, Volume 15., x, 190
Book
Nature, ISSN 0028-0836, 2012, Volume 486, Issue 7405, pp. 104 - 108
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2013, Volume 123, Issue 4, pp. 1513 - 1530
Patients with cholestatic disease exhibit pruritus and analgesia, but the mechanisms underlying these symptoms are unknown. We report that bile acids, which... 
MEDICINE, RESEARCH & EXPERIMENTAL | GENE-RELATED PEPTIDE | INTRATHECAL MORPHINE | SYNAPTIC-TRANSMISSION | GPBAR1 TGR5 | LEUCINE-ENKEPHALIN | SPINAL-CORD | SUBSTANCE-P | CEREBROSPINAL-FLUID | SENSORY NEURONS | RAT MODEL | Spinal Cord - secretion | Bile Acids and Salts - pharmacology | Opioid Peptides - physiology | Spinal Cord - metabolism | Cholestasis - complications | Cholestasis - metabolism | Receptors, G-Protein-Coupled - metabolism | Capsaicin - pharmacology | Male | Receptors, G-Protein-Coupled - agonists | Pain - metabolism | Action Potentials | Pain Perception - drug effects | Gastrin-Releasing Peptide - secretion | Pain - etiology | Female | Pruritus - etiology | Neurons - metabolism | Neurons - drug effects | Single-Cell Analysis | Enkephalin, Leucine - secretion | Receptors, G-Protein-Coupled - physiology | Gene Expression | Mice, Inbred C57BL | Cells, Cultured | Rats | Bile Acids and Salts - metabolism | Organ Specificity | Opioid Peptides - metabolism | Rats, Sprague-Dawley | Ganglia, Spinal - secretion | Mice, Knockout | Macrophages - metabolism | Patch-Clamp Techniques | Pruritus - metabolism | Animals | Ganglia, Spinal - pathology | Dermis - pathology | Mice | Receptors, G-Protein-Coupled - genetics | Bile Acids and Salts - physiology | Ganglia, Spinal - drug effects | Ganglia, Spinal - metabolism | Complications and side effects | Jaundice, Obstructive | Bile acids | Pain | Development and progression | Pruritus | Health aspects | Cholestasis | Index Medicus | Abridged Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7456, pp. 97 - 101
Obesity has become more prevalent in most developed countries over the past few decades, and is increasingly recognized as a major risk factor for several... 
HEPATOCELLULAR-CARCINOMA | HEPATIC STELLATE CELLS | ACID | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | PHENOTYPE | BACTERIUM | MECHANISMS | STRESS | EXPRESSION | CLOSTRIDIUM | Fatty Liver - pathology | Carcinoma, Hepatocellular - prevention & control | Humans | Fatty Liver - complications | Cellular Senescence - drug effects | Hepatic Stellate Cells - metabolism | Liver Neoplasms - complications | Male | Hepatic Stellate Cells - cytology | Interleukin-1beta - deficiency | Liver Neoplasms - etiology | Carcinoma, Hepatocellular - complications | Dietary Fats - pharmacology | Non-alcoholic Fatty Liver Disease | Carcinoma, Hepatocellular - etiology | Disease Models, Animal | Hepatic Stellate Cells - drug effects | DNA Damage - drug effects | Hepatic Stellate Cells - secretion | Liver Neoplasms - prevention & control | Bacteria - metabolism | Dietary Fats - adverse effects | Obesity - chemically induced | Cytokines - metabolism | Deoxycholic Acid - blood | Mice, Inbred C57BL | Risk Factors | Cells, Cultured | Cytokines - secretion | Gastrointestinal Tract - microbiology | Bile Acids and Salts - metabolism | Gastrointestinal Tract - drug effects | Gastrointestinal Tract - metabolism | Obesity - metabolism | Phenotype | Animals | Deoxycholic Acid - metabolism | Liver Neoplasms - metabolism | Anti-Bacterial Agents - pharmacology | Mice | Carcinoma, Hepatocellular - metabolism | Liver cancer | Obesity | Microbial metabolism | Development and progression | Genetic aspects | Research | Health aspects | Proteins | Cell growth | Weight control | Rodents | Index Medicus
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 60, Issue 4, pp. 824 - 831
Journal Article
Cell Metabolism, ISSN 1550-4131, 2009, Volume 10, Issue 3, pp. 167 - 177
Journal Article
Science, ISSN 0036-8075, 05/2018, Volume 360, Issue 6391, p. eaan5931
Journal Article