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The American Journal of Pathology, ISSN 0002-9440, 2006, Volume 168, Issue 2, pp. 410 - 422
We determined the mechanisms of hepatobiliary injury in the lithocholic acid (LCA)-fed mouse, an increasingly used model of cholestatic liver injury. Swiss... 
CONJUGATE EXPORT PUMP | RAT-LIVER | TAUROLITHOCHOLIC ACID | URSODEOXYCHOLIC ACID | TRANSPORTER EXPRESSION | SALT TRANSPORTERS | MOUSE-LIVER | INDUCED CHOLESTASIS | PATHOLOGY | SCANNING ELECTRON-MICROSCOPY | KNOCKOUT MICE | Cholestasis - metabolism | Liver Diseases - pathology | Fluorescence | Male | Fibrosis - metabolism | RNA, Messenger - metabolism | Organic Anion Transporters - metabolism | Organic Anion Transporters, Sodium-Dependent - genetics | Liver - injuries | Organic Anion Transporters - genetics | Liver - drug effects | Membrane Transport Proteins - genetics | Membrane Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - genetics | Sulfotransferases - metabolism | Cholangitis - metabolism | Biliary Tract Diseases - chemically induced | Lithocholic Acid - toxicity | Sulfotransferases - genetics | Cholangitis - chemically induced | Fibrosis - chemically induced | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Bile Acids and Salts - metabolism | Cholestasis - chemically induced | Reverse Transcriptase Polymerase Chain Reaction | Symporters - metabolism | Cholestasis - pathology | Animals | Diet | Symporters - genetics | Chemical and Drug Induced Liver Injury | Detergents - toxicity | Mice | Biliary Tract Diseases - pathology | Fibrosis - pathology | Liver Diseases - metabolism | Biliary Tract Diseases - metabolism | Multidrug Resistance-Associated Proteins - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | Index Medicus | Abridged Index Medicus | Original Research Paper
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2014, Volume 281, Issue 3, pp. 303 - 309
NSC-743380 (1-[(3-chlorophenyl)-methyl]-1H-indole-3-carbinol) is in early stages of development as an anticancer agent. Two metabolites reflect sequential... 
Indole-3-carbinol | Biliary hyperplasia | Rat liver | Hepatotoxicity | CHOLANGIOCYTES | LIVER | PHARMACOLOGY & PHARMACY | PROLIFERATION | TOXICOLOGY | Liver - pathology | Drugs, Investigational - adverse effects | Hyperplasia | Rats, Inbred F344 | Drugs, Investigational - pharmacokinetics | Male | Drugs, Investigational - metabolism | Structure-Activity Relationship | Antineoplastic Agents - administration & dosage | Liver - physiopathology | Indoles - administration & dosage | Antineoplastic Agents - metabolism | Dose-Response Relationship, Drug | Indoles - metabolism | Liver - drug effects | Antineoplastic Agents - adverse effects | Biliary Tract - metabolism | Biotransformation | Antineoplastic Agents - pharmacokinetics | Chemical and Drug Induced Liver Injury - blood | Chemical and Drug Induced Liver Injury - pathology | Biliary Tract Diseases - chemically induced | Drug Evaluation, Preclinical - methods | Acute Disease | Administration, Oral | Liver - metabolism | Indoles - blood | Biomarkers - blood | Random Allocation | Chemical and Drug Induced Liver Injury - physiopathology | Biliary Tract - pathology | Animals | Indoles - adverse effects | Biliary Tract Diseases - blood | Chemical and Drug Induced Liver Injury - metabolism | Drugs, Investigational - administration & dosage | Indoles - pharmacokinetics | Biliary Tract Diseases - pathology | Biliary Tract Diseases - metabolism | Biliary Tract - drug effects | Chemical properties | Metabolites | Methanol | Index Medicus | FORMATES | METABOLITES | METHANOL | NEOPLASMS | TRANSCRIPTION | RATS | TOXICITY | ALKALINE PHOSPHATASE | 60 APPLIED LIFE SCIENCES | INDOLES | MOLECULES | DOSES | BIOLOGICAL MARKERS | IN VITRO | ORAL ADMINISTRATION | WEIGHT | UREA | BLOOD | indole-3-carbinol | hepatotoxicity | biliary hyperplasia | rat liver
Journal Article
BMC Complementary and Alternative Medicine, ISSN 1472-6882, 03/2012, Volume 12, Issue 1, pp. 33 - 33
Background: Huangqi decoction was first described in Prescriptions of the Bureau of Taiping People's Welfare Pharmacy in Song Dynasty (AD 1078), and it is an... 
Extracellular signal-regulated kinase | Smad-signaling pathway | Transforming growth factor beta 1 | Cholestatic liver fibrosis | Ingredients of huangqi decoction | TGF-BETA | SMAD3 | LIVER FIBROSIS | CHOLESTASIS | INJURY | RATS | TRANSDUCTION | Ingredients of Huangqi decoction | HEPATIC STELLATE CELLS | INTEGRATIVE & COMPLEMENTARY MEDICINE | TISSUES | EXPRESSION | Fibrosis - drug therapy | Liver - pathology | Common Bile Duct - drug effects | Transforming Growth Factor beta1 - metabolism | Liver Diseases - pathology | Drugs, Chinese Herbal - pharmacology | Male | Smad3 Protein - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Ligation | Liver - drug effects | Common Bile Duct - pathology | Phytotherapy | Drugs, Chinese Herbal - therapeutic use | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Liver - metabolism | Rats | Astragalus Plant | Random Allocation | Rats, Sprague-Dawley | Biliary Tract Diseases - drug therapy | Common Bile Duct - metabolism | Animals | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Liver - cytology | Liver Diseases - drug therapy | Biliary Tract Diseases - pathology | Liver Diseases - metabolism | Biliary Tract Diseases - metabolism | Proteins | Kinases | Liver cirrhosis | Rodents | Bile | Index Medicus | Smad-signaling pathway, Extracellular signal-regulated kinase
Journal Article
Cancer, ISSN 0008-543X, 10/2004, Volume 101, Issue 7, pp. 1609 - 1615
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e67091 - e67091
Journal Article
Histopathology, ISSN 0309-0167, 11/2011, Volume 59, Issue 5, pp. 867 - 875
Aishima S, Iguchi T, Fujita N, Taketomi A, Maehara Y, Tsuneyoshi M & Oda Y (2011) Histopathology 59 , 867–875 Histological and immunohistological findings in... 
MUC | hepatitis |