X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2098) 2098
Publication (398) 398
Book Chapter (24) 24
Conference Proceeding (13) 13
Dissertation (10) 10
Book Review (5) 5
Data Set (1) 1
Government Document (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
apoptosis (1545) 1545
bim (1225) 1225
index medicus (1212) 1212
humans (1054) 1054
animals (936) 936
bcl-2-like protein 11 (701) 701
mice (672) 672
cell biology (626) 626
proteins (511) 511
proto-oncogene proteins - metabolism (510) 510
apoptosis regulatory proteins - metabolism (508) 508
oncology (504) 504
bim protein (496) 496
biochemistry & molecular biology (496) 496
membrane proteins - metabolism (481) 481
cell line, tumor (444) 444
apoptosis - drug effects (442) 442
cancer (436) 436
phosphorylation (399) 399
expression (394) 394
proto-oncogene proteins - genetics (366) 366
apoptosis regulatory proteins - genetics (365) 365
activation (360) 360
membrane proteins - genetics (357) 357
signal transduction (332) 332
cell death (292) 292
gene expression (272) 272
female (268) 268
proto-oncogene proteins c-bcl-2 - metabolism (268) 268
immunology (265) 265
article (264) 264
survival (253) 253
bcl-2 (249) 249
bcl-2 family (242) 242
death (232) 232
mitochondria (232) 232
male (231) 231
kinases (220) 220
bax (213) 213
family-member bim (213) 213
apoptosis - physiology (208) 208
bcl-2 protein (206) 206
bh3-only proteins (203) 203
mice, inbred c57bl (194) 194
hemic and lymphatic diseases (192) 192
cell-death (188) 188
research (187) 187
multidisciplinary sciences (186) 186
cell survival (183) 183
mice, knockout (181) 181
biological phenomena, cell phenomena, and immunity (172) 172
cells, cultured (169) 169
in-vivo (169) 169
inhibition (169) 169
apoptosis - genetics (162) 162
mutation (159) 159
medicine (158) 158
cells (157) 157
biology (156) 156
research article (153) 153
antineoplastic agents - pharmacology (151) 151
proto-oncogene proteins c-bcl-2 - genetics (149) 149
tumors (145) 145
cell line (144) 144
rats (143) 143
down-regulation (142) 142
chemotherapy (140) 140
caspase (138) 138
cell cycle (137) 137
hematology (137) 137
science (136) 136
analysis (135) 135
flow cytometry (135) 135
cell proliferation (133) 133
mcl-1 (133) 133
genetic aspects (132) 132
health aspects (132) 132
up-regulation (128) 128
rodents (127) 127
induced apoptosis (126) 126
pathway (126) 126
signal transduction - drug effects (126) 126
mitochondria - metabolism (125) 125
protein (123) 123
bax protein (119) 119
leukemia (119) 119
resistance (117) 117
mice, transgenic (116) 116
neoplasms (110) 110
physiological aspects (108) 108
rna interference (104) 104
cell lines (103) 103
lymphocytes (103) 103
apoptosis regulatory proteins (102) 102
transcription factors (102) 102
bcl-2-associated x protein - metabolism (101) 101
blotting, western (101) 101
protein binding (101) 101
homeostasis (100) 100
oxidative stress (100) 100
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2104) 2104
Chinese (15) 15
French (6) 6
Japanese (4) 4
Swedish (2) 2
Polish (1) 1
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Science, ISSN 0036-8075, 2/2007, Volume 315, Issue 5813, pp. 856 - 859
A central issue in the regulation of apoptosis by the Bcl-2 family is whether its BH3-only members initiate apoptosis by directly binding to the essential... 
Research fellowships | Protein isoforms | Medical research | Myeloid cells | Antibodies | Cytochromes | Ligands | Reports | Grants | Viability | Apoptosis | RESPONSES | FAMILY-MEMBERS | X-L | MULTIDISCIPLINARY SCIENCES | BIM | HELIX | MITOCHONDRIAL-MEMBRANE | PUMA | DOMAINS | BH3-ONLY PROTEINS | CELL-DEATH | bcl-2-Associated X Protein - chemistry | Humans | BH3 Interacting Domain Death Agonist Protein - genetics | Proto-Oncogene Proteins - chemistry | Neoplasm Proteins - metabolism | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | Tumor Suppressor Proteins - genetics | BH3 Interacting Domain Death Agonist Protein - chemistry | Apoptosis Regulatory Proteins - genetics | bcl-Associated Death Protein - metabolism | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Apoptosis Regulatory Proteins - chemistry | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Proteins - metabolism | Membrane Proteins - chemistry | Models, Biological | Myeloid Cell Leukemia Sequence 1 Protein | Mice | Mutation | bcl-X Protein - metabolism | Research | Peptides | Analysis | Biochemistry | Cellular biology | Molecular biology | Binding sites
Journal Article
Molecular Cell, ISSN 1097-2765, 2005, Volume 17, Issue 3, pp. 393 - 403
Apoptosis is initiated when Bcl-2 and its prosurvival relatives are engaged by proapoptotic BH3-only proteins via interaction of its BH3 domain with a groove... 
CYTOCHROME-C | COMPLEX | SURVIVAL FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | BIM | RELEASE | PEPTIDE | CELL-DEATH | FAMILY | MEMBER | CELL BIOLOGY | Humans | Molecular Sequence Data | Proto-Oncogene Proteins - chemistry | Neoplasm Proteins - metabolism | Genetic Complementation Test | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | Carrier Proteins - chemistry | Proto-Oncogene Proteins c-bcl-2 - chemistry | Membrane Proteins - metabolism | Neoplasm Proteins - genetics | Peptide Fragments - genetics | Cell Survival - physiology | Binding, Competitive | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | bcl-X Protein | Peptide Fragments - metabolism | Membrane Proteins - genetics | Models, Molecular | Recombinant Proteins - chemistry | Neoplasm Proteins - chemistry | Proto-Oncogene Proteins - genetics | Recombinant Proteins - genetics | Proteins - genetics | Sequence Homology, Amino Acid | Carrier Proteins - genetics | Peptide Fragments - chemistry | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Proteins - metabolism | Membrane Proteins - chemistry | Models, Biological | Myeloid Cell Leukemia Sequence 1 Protein | Biosensing Techniques | Ligands | Mice | Apoptosis - physiology | Proteins - chemistry | In Vitro Techniques | Proto-Oncogene Proteins c-bcl-2 - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, p. e39586
Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson Disease, Alzheimer Disease... 
MITOCHONDRIAL APOPTOSIS | TRANSCRIPTION FACTOR CHOP | UNFOLDED PROTEIN RESPONSE | INDUCED APOPTOSIS | KINASE | BIOLOGY | GENE-EXPRESSION | SYMPATHETIC NEURONS | DEATH | ENDOPLASMIC-RETICULUM STRESS | BH3-ONLY PROTEINS | Transcription Factor CHOP - genetics | Apoptosis - drug effects | Neurons - cytology | Bcl-2-Like Protein 11 | Forkhead Transcription Factors - metabolism | Telencephalon - drug effects | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Neurons - metabolism | Neurons - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Cell Survival - physiology | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Tumor Suppressor Proteins - metabolism | Telencephalon - metabolism | Telencephalon - cytology | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Forkhead Transcription Factors - genetics | Apoptosis Regulatory Proteins - metabolism | Animals | Signal Transduction - drug effects | Tunicamycin - pharmacology | Signal Transduction - physiology | Mice | Apoptosis - physiology | Forkhead Box Protein O3 | Transcription Factor CHOP - metabolism | Endoplasmic Reticulum Stress - physiology | Nervous system diseases | Parkinson's disease | Huntington's chorea | Neurons | Tumor proteins | Protein kinases | Apoptosis | Phosphorylation | Transcription factors | Transcription | p53 Protein | Tunicamycin | Homology | AKT protein | CCAAT/enhancer-binding protein | Kinases | Proteins | Signal transduction | Mitochondria | Cell activation | Cell growth | Cascades | Rodents | Forkhead protein | Alzheimer's disease | Movement disorders | Deoxyribonucleic acid--DNA | FOXO3 protein | Stresses | Neurodegenerative diseases | Mortality | Gene expression | Stress | Neurological diseases | Pathology | Signaling | Cell death | Endoplasmic reticulum | CHOP protein | BIM protein | Deoxyribonucleic acid | DNA
Journal Article
Nature Communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, p. 16078
BCL-2 family proteins are central regulators of mitochondrial apoptosis and validated anticancer targets. Using small cell lung cancer (SCLC) as a model, we... 
CELL LUNG-CANCER | SELECTIVE-INHIBITION | BAK ACTIVATION | POTENT | MULTIDISCIPLINARY SCIENCES | BIM | TRANSCRIPTION | DEATH | CDK INHIBITOR | ABT-263 | BH3 DOMAIN | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Drug Resistance, Neoplasm | Molecular Targeted Therapy | Apoptosis Regulatory Proteins - drug effects | Myeloid Cell Leukemia Sequence 1 Protein - drug effects | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | bcl-X Protein - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | bcl-X Protein - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Aniline Compounds - pharmacology | Cyclin-Dependent Kinase 9 - antagonists & inhibitors | Sulfonamides - pharmacology | Apoptosis Regulatory Proteins - metabolism | Drug Synergism | Pyridinium Compounds - pharmacology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | High-Throughput Screening Assays | Apoptosis Regulatory Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - drug effects | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | bcl-X Protein - metabolism | Doxorubicin - pharmacology | Regulators | Bax protein | Bcl-2 protein | Small cell lung carcinoma | Lung cancer | High-throughput screening | Doxorubicin | BAK protein | Mcl-1 protein | Proteins | Mitochondria | Inhibitors | Bcl-x protein | Anthracycline | Addiction | Cell death | Sequestering | Cancer | Apoptosis
Journal Article
Nature Communications, ISSN 2041-1723, 03/2017, Volume 8, Issue 1, p. 14687
Journal Article
Oncogene, ISSN 0950-9232, 10/2003, Volume 22, Issue 43, pp. 6785 - 6793
Bim is a proapoptotic member of the Bcl-2 family that shares only the BH3 domain with this family. Three Bim proteins Bim-EL, Bim-L and Bim-S are synthesized... 
Erk1/2 | Bim | Apoptosis | Proteasome | proteasome | ACTIVATION | BAD | BIOCHEMISTRY & MOLECULAR BIOLOGY | BCL-2 FAMILY MEMBER | apoptosis | DEATH | INDUCTION | CELL-SURVIVAL | CELL BIOLOGY | ONCOLOGY | SIGNALING PATHWAY | GENETICS & HEREDITY | EXPRESSION | DEPENDENT DEGRADATION | Phosphorylation | Tetradecanoylphorbol Acetate | Humans | Molecular Sequence Data | Multienzyme Complexes - metabolism | Proteasome Endopeptidase Complex | Lymphoma - metabolism | Caspases - metabolism | Cysteine Endopeptidases - metabolism | Transfection | Bcl-2-Like Protein 11 | Time Factors | Carrier Proteins - chemistry | Proto-Oncogene Proteins | Tumor Cells, Cultured | Binding Sites | Amino Acid Sequence | Cell Line | Antineoplastic Agents, Hormonal - pharmacology | Cell Survival | Gene Expression Regulation | Glutathione Transferase - metabolism | Serine - chemistry | Proto-Oncogene Proteins c-raf - metabolism | Membrane Proteins | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Models, Biological | Protein Isoforms | K562 Cells | Tamoxifen - pharmacology | Mitogen-Activated Protein Kinase 3 | Mitogen-Activated Protein Kinase 1 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Bim-L protein | Bim-EL protein | Bim-S protein | Bim protein | Multienzyme Complexes | Serine | Life Sciences | Glutathione Transferase | Carrier Proteins | Mitogen-Activated Protein Kinases | Cysteine Endopeptidases | Antineoplastic Agents, Hormonal | Proto-Oncogene Proteins c-raf | Biochemistry, Molecular Biology | Tamoxifen | Lymphoma | Caspases | Mitogen-Activated Protein Kinase 1 | Molecular biology | Cancer
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2012, Volume 18, Issue 9, pp. 2502 - 2514
Purpose: The clinical use of BRAF inhibitors is being hampered by the acquisition of drug resistance. This study shows the potential therapeutic use of the... 
BREAST-CANCER | MULTIPLE-MYELOMA | APOPTOSIS | PHASE-II TRIAL | TANESPIMYCIN 17-AAG | TRASTUZUMAB | ONCOLOGY | BIM | ACQUIRED-RESISTANCE | MELANOMA-CELLS | POTENTIAL MECHANISM | Prospective Studies | Apoptosis - drug effects | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Immunoenzyme Techniques | Forkhead Transcription Factors - metabolism | Colony-Forming Units Assay | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Phthalic Acids - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Real-Time Polymerase Chain Reaction | Proto-Oncogene Proteins B-raf - metabolism | Membrane Proteins - genetics | Melanoma - pathology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Indoles - adverse effects | Membrane Proteins - antagonists & inhibitors | Signal Transduction - drug effects | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Cell Line, Tumor | HSP90 Heat-Shock Proteins - metabolism | Mice | Mice, Inbred BALB C | Forkhead Box Protein O3 | Azabicyclo Compounds - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Flow Cytometry | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Forkhead Transcription Factors - antagonists & inhibitors | Melanoma - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Proto-Oncogene Proteins - genetics | Forkhead Transcription Factors - genetics | Phosphatidylinositol 3-Kinases - genetics | Animals | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Myeloid Cell Leukemia Sequence 1 Protein | Apoptosis Regulatory Proteins - antagonists & inhibitors | Fluorescent Antibody Technique | Sulfonamides - adverse effects | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Proto-Oncogene Proteins c-bcl-2 - genetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 02/2013, Volume 210, Issue 2, pp. 269 - 285
Acquisition of self-tolerance in the thymus requires T cells to discriminate strong versus weak T cell receptor binding by self-peptide-MHC complexes. We find... 
DEVELOPING THYMOCYTES | MEDICINE, RESEARCH & EXPERIMENTAL | TISSUE-RESTRICTED ANTIGENS | SELF-PEPTIDE | RECEPTOR TRANSGENIC MICE | IN-VIVO | BIM | NEGATIVE SELECTION | C-MYC | CLONAL DELETION | IMMUNOLOGY | EXPRESSION | Autoimmunity | Cell Proliferation | NF-kappa B - immunology | Proto-Oncogene Proteins c-rel - metabolism | Proto-Oncogene Proteins - biosynthesis | Proto-Oncogene Proteins c-rel - immunology | CARD Signaling Adaptor Proteins - genetics | CD4-Positive T-Lymphocytes - immunology | Membrane Proteins - deficiency | CARD Signaling Adaptor Proteins - metabolism | Bcl-2-Like Protein 11 | Receptors, CCR7 - metabolism | Apoptosis Regulatory Proteins - deficiency | Programmed Cell Death 1 Receptor - biosynthesis | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Transcription Factors - immunology | Apoptosis Regulatory Proteins - biosynthesis | CARD Signaling Adaptor Proteins - immunology | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Lymphocyte Activation | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Self Tolerance | Membrane Proteins - immunology | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Transcription Factors - biosynthesis | Proto-Oncogene Proteins - deficiency | Clonal Deletion - immunology | Mice, Knockout | Membrane Proteins - biosynthesis | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-rel - genetics | NF-kappa B - biosynthesis | Mice | Mutation | Programmed Cell Death 1 Receptor - immunology | DNA-Binding Proteins - biosynthesis | 309
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/2008, Volume 181, Issue 11, pp. 7617 - 7629
The magnitude of T cell responses is determined by proliferation and survival decisions made by the responding cells. We now demonstrate that the Erk MAPK... 
LOOP-HELIX PROTEINS | IMMUNE-RESPONSE | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | SIGNALING PATHWAYS | ACTIVATED PROTEIN-KINASE | IN-VIVO | NEGATIVE SELECTION | IMMUNOLOGY | FAMILY-MEMBER BIM | VIRAL-INFECTION | THYMOCYTE DIFFERENTIATION | Cell Proliferation | bcl-X Protein - genetics | Cell Survival - genetics | MAP Kinase Signaling System - immunology | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | MAP Kinase Signaling System - genetics | Bcl-2-Like Protein 11 | Mitogen-Activated Protein Kinase 1 - genetics | Proto-Oncogene Proteins - immunology | bcl-X Protein - immunology | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Apoptosis Regulatory Proteins - immunology | Mitogen-Activated Protein Kinase 1 - immunology | Mitogen-Activated Protein Kinase 3 - genetics | Membrane Proteins - genetics | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | Cell Survival - immunology | Apoptosis Regulatory Proteins - metabolism | CD8-Positive T-Lymphocytes - enzymology | Mice, Knockout | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Transcription, Genetic - immunology | Mice | Transcription, Genetic - genetics | CD8-Positive T-Lymphocytes - immunology | bcl-X Protein - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2004, Volume 24, Issue 36, pp. 7879 - 7887
The c-Jun N-terminal protein kinase (JNK) signaling pathway is implicated in neuronal apoptosis. The mechanism by which activated JNK induces neuronal... 
Bax | c-Jun N-terminal kinase | Cerebral ischemia | Bim | Apoptosis | SP600125 | HIPPOCAMPAL CA1 NEURONS | BCL-2 FAMILY MEMBERS | apoptosis | TRANSDUCTION | DEPENDENT APOPTOSIS | INDUCE APOPTOSIS | RELEASE | NEUROSCIENCES | CELL-DEATH | CYTOCHROME-C | JNK PHOSPHORYLATION | cerebral ischemia | BH3-ONLY PROTEINS | Neurons - pathology | Phosphorylation | Proto-Oncogene Proteins c-bcl-2 - physiology | Mitogen-Activated Protein Kinase Kinases - physiology | Male | MAP Kinase Signaling System | MAP Kinase Kinase 4 | Bcl-2-Like Protein 11 | Membrane Proteins - physiology | Neurons - metabolism | Protein-Serine-Threonine Kinases - metabolism | Carrier Proteins - physiology | Dyneins - metabolism | Proto-Oncogene Proteins - metabolism | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Molecular Motor Proteins | Rats | Mitochondria - metabolism | Infarction, Middle Cerebral Artery - pathology | bcl-2-Associated X Protein | Rats, Sprague-Dawley | Anthracenes - pharmacology | Protein Interaction Mapping | Protein Transport | Proto-Oncogene Proteins c-akt | Animals | Apoptosis Regulatory Proteins | JNK Mitogen-Activated Protein Kinases - physiology | Proto-Oncogene Proteins - physiology | Signal Transduction - physiology | Protein Processing, Post-Translational | Apoptosis - physiology | Neurobiology of Disease
Journal Article
Science, ISSN 0036-8075, 9/2001, Volume 293, Issue 5536, pp. 1829 - 1832
Bcl-2 family members bearing only the BH3 domain are essential inducers of apoptosis. We identified a BH3-only protein, Bmf, and show that its BH3 domain is... 
T lymphocytes | Messenger RNA | HEK293 cells | Spleen cells | CDNA libraries | Cell lines | Cellulose nitrate | Antibodies | Reports | Family members | Apoptosis | APOPTOSIS | DYNEIN | INTEGRINS | MULTIDISCIPLINARY SCIENCES | LIGHT-CHAIN | BIM | PURIFICATION | BCL-2 FAMILY | CELL-DEATH | MEMBER | Humans | Molecular Sequence Data | RNA, Messenger - analysis | Gene Expression Profiling | Neoplasm Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Transfection | Bcl-2-Like Protein 11 | Carrier Proteins - chemistry | Molecular Motor Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - chemistry | Proto-Oncogene Proteins | Neoplasm Proteins - genetics | Dyneins | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Drosophila Proteins | RNA, Messenger - genetics | Calmodulin-Binding Proteins - metabolism | Myosin Type V | Protein Transport | Membrane Proteins | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Two-Hybrid System Techniques | Adaptor Proteins, Signal Transducing | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Myeloid Cell Leukemia Sequence 1 Protein | Cytoskeleton - metabolism | Protein Binding | Anoikis | Mice | Mutation | Proto-Oncogene Proteins c-bcl-2 - genetics | Proteins | Genetic research | Genetic aspects | Analysis | Cellular biology | Cells
Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 1, p. e86629
Osteoblast apoptosis plays an important role in bone development and maintenance, and is in part responsible for osteoporosis in sex steroid deficiency,... 
TRANSCRIPTION FACTORS | APOPTOSIS | OXIDATIVE STRESS | CELL-CYCLE ENTRY | BONE-FORMATION | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | IN-VIVO | PARATHYROID-HORMONE | DEATH | P53 | Up-Regulation | Mice, Inbred C57BL | Forkhead Transcription Factors - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | Forkhead Transcription Factors - metabolism | Gene Deletion | Cell Differentiation | Forkhead Box Protein O1 | Mice | Osteoblasts - cytology | Forkhead Box Protein O3 | Osteoblasts - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Osteogenesis | Apoptosis | Physiological aspects | Corticosteroids | DNA binding proteins | Tumor proteins | Cell culture | Oxidative stress | Transcription factors | Phosphorylation | Glucocorticoids | p53 Protein | Bromodeoxyuridine | AKT protein | Biology | Insulin-like growth factors | Kinases | Inactivation | Osteoblasts | Cell density | Proteins | Osteoporosis | Biomedical materials | Cell growth | FOXO1 protein | Bcl-x protein | Transgenic animals | Rodents | Surgery | Cell cycle | Aging | Forkhead protein | Insulin-like growth factor-binding protein 3 | Biocompatibility | Bones | Physiology | FOXO3 protein | University graduates | Osteocalcin | Deactivation | Gene expression | Insulin | DNA nucleotidylexotransferase | Osteoblastogenesis | Gadd45A protein | FasL protein | Cell death | Differentiation | BIM protein | PTEN protein
Jou