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International Journal of Cancer, ISSN 0020-7136, 09/2015, Volume 137, Issue 5, pp. 1095 - 1106
Indoleamine 2,3‐dioxygenase (IDO) has been reported to be involved in esophageal squamous cell cancer (ESCC) progression by promoting immune escape. Previous... 
bridging integrator‐1 (Bin1) | indoleamine 2,3‐dioxygenase (IDO) | prognosis | esophageal squamous cell cancer (ESCC) | immuno‐editing | immuno-editing | indoleamine 2,3-dioxygenase (IDO) | bridging integrator-1 (Bin1) | TARGET | SUPPRESSION GENE BIN1 | MECHANISM | CONVERSION | INDOLEAMINE 2,3-DIOXYGENASE | METASTASES | C-MYC | indoleamine 2 | ONCOLOGY | PATHWAY | 3-dioxygenase (IDO) | T-CELLS | LYMPHOCYTES | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Lymph Nodes - pathology | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Male | Esophageal Neoplasms - pathology | Esophageal Neoplasms - metabolism | Lymphatic Metastasis - pathology | Tumor Suppressor Proteins - genetics | Adult | Female | Nuclear Proteins - genetics | Lymphocytes - metabolism | Tumor Suppressor Proteins - metabolism | Lymph Nodes - metabolism | Nuclear Proteins - metabolism | Esophageal Neoplasms - genetics | Adaptor Proteins, Signal Transducing - genetics | Aged | Adaptor Proteins, Signal Transducing - metabolism | Immunohistochemistry | Fc receptors | Analysis | Development and progression | T cells | Esophageal cancer | Tumors | Survival analysis | Lymphatic system | Medical prognosis
Journal Article
Journal Article
Genetics and Molecular Biology, ISSN 1415-4757, 08/2019
Abstract Genome-wide associations studies (GWAS) have been detecting new variants associated with late-onset of Alzheimer’s disease (LOAD), a multifactorial... 
ABCA7 | APOE | GWAS variants | BIN1 | CLU
Journal Article
Science Translational Medicine, ISSN 1946-6234, 2019, Volume 11, Issue 484, p. eaav1866
Centronuclear myopathies (CNMs) are severe diseases characterized by muscle weakness and myofiber atrophy. Currently, there are no approved treatments for... 
MEDICINE, RESEARCH & EXPERIMENTAL | MUTATIONS | BIN1 | EXPRESSION | CELL BIOLOGY
Journal Article
EMBO reports, ISSN 1469-221X, 11/2017, Volume 18, Issue 11, pp. 2051 - 2066
Endocytic processes are facilitated by both curvature‐generating BAR ‐domain proteins and the coordinated polymerization of actin filaments. Under... 
protein Bin1 | tau | BAR | Alzheimer's disease | actin binding | genetic risk factor | N-BAR protein Bin1 | PROTEIN | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CROSS-LINKING | FILAMENT TURNOVER | TAU PATHOLOGY | CELL BIOLOGY | SKELETAL-MUSCLE | STRUCTURAL BASIS | SYNAPTIC VESICLE ENDOCYTOSIS | MEMBRANE CURVATURE | SH3 DOMAIN | Tauopathies - genetics | Humans | Actins - metabolism | Tauopathies - pathology | tau Proteins - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Actins - genetics | Drosophila melanogaster - metabolism | Protein Isoforms - metabolism | tau Proteins - genetics | Tumor Suppressor Proteins - genetics | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Nuclear Proteins - genetics | Binding Sites | Actin Cytoskeleton - genetics | Disease Models, Animal | Recombinant Proteins - metabolism | Gene Expression | Tumor Suppressor Proteins - metabolism | Actin Cytoskeleton - metabolism | Genetic Vectors - chemistry | Gene Expression Regulation | Genetic Vectors - metabolism | Nuclear Proteins - metabolism | Recombinant Proteins - genetics | Transcription Factors - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Tauopathies - metabolism | Animals | Carrier Proteins - metabolism | Escherichia coli - genetics | Adaptor Proteins, Signal Transducing - genetics | Protein Binding | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Protein Isoforms - genetics | Membranes | Neurodegenerative diseases | Drosophila | Health risks | Polymerization | Rods | Bundles | Risk factors | Membrane proteins | Bundling | Proteins | Depolymerization | Insects | Tau protein | Filaments | Neurodegeneration | Actin | Isoforms | BAR protein | Cytoskeleton | Alzheimers disease | Curvature | N‐BAR protein Bin1 | Neuroscience | Cell Adhesion, Polarity & Cytoskeleton
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2018, Volume 505, Issue 2, pp. 365 - 371
Amphiphysin 2 and members of the BAR-domain family of proteins participate in a wide array of cellular processes including cell cycle and endocytosis. Given... 
Oxidative stress | Cell survival | c-Myc | Lipoprotein internalization | Bin1/Amphiphysin | TUMOR-SUPPRESSOR BIN1 | APOPTOSIS | DOMAIN | PROTEIN | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOPHYSICS | SMOOTH-MUSCLE-CELLS | DYNAMIN | BINDING | Blood lipids | Macrophages | Cell death | Low density lipoproteins
Journal Article
Lung Cancer, ISSN 0169-5002, 04/2019, Volume 130, pp. 35 - 41
A number of key immune regulators show prognostic value in malignant pleural mesothelioma (MPM), but the association between Bridging integrator 1 (BIN1),... 
Prognosis | Tumor infiltrating lymphocytes | BIN1 | Biomarkers | PD-L1 | Mesothelioma | Macrophages | IDO1 | IMMUNE CELLS | SUPPRESSOR BIN1 | INDOLEAMINE 2,3-DIOXYGENASE | INHIBITION | ONCOLOGY | IMMUNOTHERAPY | RESPIRATORY SYSTEM | INFLAMMATION | T-CELLS | PROGRESSION | CANCER-IMMUNITY | Immunohistochemistry | Lymphocytes | Analysis | Tumors
Journal Article
Journal Article
Virology, ISSN 0042-6822, 08/2019, Volume 537, pp. 130 - 142
Alphavirus nsP3 proteins contain long, intrinsically disordered, hypervariable domains, HVD, which serve as hubs for interaction with many cellular proteins.... 
Journal Article