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RSC Advances, ISSN 2046-2069, 2017, Volume 7, Issue 69, pp. 43764 - 43771
New mechanical biomarkers were discovered and used to investigate drug effects on HeLa cells. HeLa cells were measured using advanced atomic force microscopy... 
NANOPARTICLES | CHALLENGE | BACTERIA | ATOMIC-FORCE MICROSCOPY | NANOMECHANICS | PRODUCTIVITY | CANCER | DOCETAXEL | CHEMISTRY, MULTIDISCIPLINARY | BIOFILM FORMATION | PACLITAXEL
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 2014, Volume 210, Issue 9, pp. 1357 - 1366
Background. Limitations in treatment of biofilm-associated bacterial infections are often due to subpopulation of persistent bacteria (persisters) tolerant to... 
aminoglycoside | persister | catheter-related infections | biofilm | proton motive force | DIAGNOSIS | INFECTIOUS DISEASES | INFECTIONS | MANAGEMENT | TOLERANCE | SUSCEPTIBILITY | MICROBIOLOGY | IMMUNOLOGY | ANTIBIOTIC-LOCK THERAPY | GENTAMICIN | PSEUDOMONAS-AERUGINOSA | L-ARGININE | GROWTH | Escherichia coli Infections - prevention & control | Central Venous Catheters - microbiology | Escherichia coli - drug effects | Gentamicins - administration & dosage | Catheter-Related Infections - prevention & control | Pseudomonas Infections - prevention & control | Arginine - administration & dosage | Gentamicins - pharmacology | Drug Therapy, Combination | Biofilms - drug effects | Escherichia coli Infections - drug therapy | Staphylococcal Infections - drug therapy | Pseudomonas Infections - drug therapy | Rats | Central Venous Catheters - adverse effects | Pseudomonas aeruginosa - drug effects | Catheter-Related Infections - drug therapy | Drug Synergism | Animals | Arginine - pharmacology | Staphylococcal Infections - prevention & control | Anti-Bacterial Agents - pharmacology | In Vitro Techniques | Staphylococcus aureus - drug effects | Hydrogen-Ion Concentration | Aminoglycosides | Health aspects | Research | Index Medicus | Abridged Index Medicus | Biofilms/drug effects | Gentamicins/administration & dosage | Anti-Bacterial Agents/pharmacology | Staphylococcal Infections/drug therapy | Arginine/administration & dosage | Life Sciences | Escherichia coli Infections/drug therapy | Staphylococcus aureus/drug effects | Gentamicins/pharmacology | Catheter-Related Infections/prevention & control | Pseudomonas aeruginosa/drug effects | Staphylococcal Infections/prevention & control | Catheter-Related Infections/drug therapy | Central Venous Catheters/microbiology | Escherichia coli/drug effects | Bacteriology | Microbiology and Parasitology | Central Venous Catheters/adverse effects | Arginine/pharmacology | Pseudomonas Infections/prevention & control | Escherichia coli Infections/prevention & control | Pseudomonas Infections/drug therapy
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 503, Issue 7476, pp. 365 - 370
Journal Article
PLoS Genetics, ISSN 1553-7390, 01/2013, Volume 9, Issue 1, pp. e1003144 - e1003144
High levels of antibiotic tolerance are a hallmark of bacterial biofilms. In contrast to well-characterized inherited antibiotic resistance, molecular... 
CELLS | BACTERIAL PERSISTENCE | PSEUDOMONAS-AERUGINOSA | ESCHERICHIA-COLI | GENETICS & HEREDITY | GENE-EXPRESSION | RESISTANCE | BETA-LACTAM ANTIBIOTICS | CYSTIC-FIBROSIS | INDUCTION | STRESS | Biofilms - drug effects | Plankton - drug effects | Starvation | Drug Tolerance - genetics | Biofilms - growth & development | Amino Acids - genetics | Ofloxacin - pharmacology | Mutagenesis | Escherichia coli - genetics | Fluoroquinolones - pharmacology | SOS Response (Genetics) | DNA Transposable Elements - genetics | Plankton - genetics | Anti-Bacterial Agents - pharmacology | Drug Resistance, Bacterial - drug effects | Escherichia coli - growth & development | Drug Resistance, Bacterial - genetics | Transposons | Antibiotics | Gene mutations | Physiological aspects | Genetic aspects | Dosage and administration | Research | Drug resistance | Health aspects | Biofilms | Microbiology | E coli | Bacteria | Mutation | Carbon | Index Medicus | Ofloxacin/pharmacology | DNA Transposable Elements/genetics | Bacterial/drug effects/genetics | Anti-Bacterial Agents/pharmacology | Plankton/drug effects/genetics | Escherichia coli/genetics/growth & development | Bacteriology | Fluoroquinolones/pharmacology | Life Sciences | Microbiology and Parasitology | Biofilms/drug effects/growth & development | Drug Tolerance/genetics | Amino Acids/genetics | Drug Resistance
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 5, pp. e1004152 - e1004152
Bacteria form multicellular communities known as biofilms that cause two thirds of all infections and demonstrate a 10 to 1000 fold increase in adaptive... 
BACTERIA | (P)PPGPP | ESCHERICHIA-COLI | ANTIBACTERIAL | MICROBIOLOGY | PPGPP | VIRULENCE | RELA | VIROLOGY | STRINGENT RESPONSE | PSEUDOMONAS | GROWTH | PARASITOLOGY | Klebsiella pneumoniae - drug effects | Salmonella typhimurium - growth & development | Escherichia coli - drug effects | Ligases - genetics | Pseudomonas aeruginosa - growth & development | Biofilms - growth & development | Burkholderia cenocepacia - genetics | Peptide Fragments - pharmacology | Genetic Complementation Test | Microbial Sensitivity Tests | Anti-Bacterial Agents - chemistry | Klebsiella pneumoniae - genetics | Salmonella typhimurium - drug effects | Stress, Physiological - drug effects | Escherichia coli - growth & development | Acinetobacter baumannii - growth & development | Methicillin-Resistant Staphylococcus aureus - genetics | Biofilms - drug effects | Burkholderia cenocepacia - growth & development | Salmonella typhimurium - genetics | Methicillin-Resistant Staphylococcus aureus - drug effects | Ligases - metabolism | Pseudomonas aeruginosa - drug effects | Methicillin-Resistant Staphylococcus aureus - growth & development | Pseudomonas aeruginosa - genetics | Burkholderia cenocepacia - drug effects | Escherichia coli - genetics | Klebsiella pneumoniae - growth & development | Anti-Bacterial Agents - pharmacology | Acinetobacter baumannii - drug effects | Acinetobacter baumannii - genetics | Antibiotics | Genetic aspects | Research | Planktonic bacteria | Microbial mats | Health aspects | Sugars | Monosaccharides | Index Medicus | Medical research | Biofilms | Peptides | Bacteria | Infections | Drug resistance | Stress response | Bacteriology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2012, Volume 109, Issue 33, pp. 13182 - 13187
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 75, pp. 203 - 222
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 05/2012, Volume 56, Issue 5, pp. 2314 - 2325
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
IN-VITRO | POLYMORPHONUCLEAR LEUKOCYTES | PSEUDOMONAS-AERUGINOSA VIRULENCE | COMPOUND | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | CHRONIC WOUNDS | CYSTIC-FIBROSIS | LUNG INFECTION | VIBRIO-HARVEYI | BACTERIAL BIOFILMS | Plant Extracts - chemistry | Biofilms - growth & development | Tobramycin - administration & dosage | Garlic - chemistry | Respiratory Tract Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Disulfides - therapeutic use | Pseudomonas aeruginosa - pathogenicity | Disulfides - pharmacology | Genes, Reporter | Tobramycin - therapeutic use | Virulence Factors - antagonists & inhibitors | Glycolipids - antagonists & inhibitors | Biofilms - drug effects | Quorum Sensing - drug effects | Pseudomonas Infections - drug therapy | Neutrophils - drug effects | Respiratory Tract Infections - drug therapy | Anti-Bacterial Agents - isolation & purification | Pseudomonas aeruginosa - drug effects | Pseudomonas Infections - microbiology | Quorum Sensing - genetics | Drug Synergism | Gene Expression Regulation, Bacterial - drug effects | Animals | Pseudomonas aeruginosa - genetics | Chemical Fractionation | Anti-Bacterial Agents - pharmacology | Mice | Disulfides - isolation & purification | Index Medicus | Drugs | Animal models | Communication systems | quorum sensing | Lung | Antimicrobial agents | virulence factors | Necrosis | Infection | Pathogenicity | Biofilms | DNA microarrays | Leukocytes (polymorphonuclear) | Tobramycin | rhamnolipids | Mechanisms of Action | Physiological Effects
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, pp. e0124595 - e0124595
Staphylococcus aureus is a Gram-positive bacterium that has become the leading cause of hospital acquired infections in the US. Repurposing Food and Drug... 
INTRINSIC RESISTANCE | EFFLUX PUMP(S) | CAENORHABDITIS-ELEGANS | EVOLUTION | VIRULENCE FACTORS | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | MODEL HOST | MRSA | INHIBITORS | IDENTIFICATION | Oxyclozanide - pharmacology | Cell Survival - drug effects | Enterococcus faecium - drug effects | Microbial Viability - drug effects | Humans | Methicillin-Resistant Staphylococcus aureus - drug effects | Drug Repositioning | Erythrocytes - drug effects | Hep G2 Cells | Microbial Sensitivity Tests | Gram-Negative Bacteria - drug effects | Methicillin-Resistant Staphylococcus aureus - growth & development | Animals | Anthelmintics - pharmacology | Niclosamide - pharmacology | Gram-Negative Bacteria - growth & development | Erythrocytes - cytology | Sheep | Anti-Bacterial Agents - pharmacology | Enterococcus faecium - growth & development | Drug Resistance, Multiple, Bacterial - drug effects | Drugs | Veterinary supplies industry | Staphylococcus aureus infections | Cross infection | Nosocomial infections | Drug resistance | Comparative analysis | Health aspects | Antibacterial agents | Drug approval | Staphylococcus aureus | Klebsiella | Linezolid | Regulatory agencies | Antimicrobial activity | Low concentrations | Laboratories | Toxicity | Liver | Erythrocytes | Daptomycin | Niclosamide | Gram-positive bacteria | Clinical isolates | Genomes | Infections | Vancomycin | Drug development | Kinases | Veterinary medicine | Antiinfectives and antibacterials | Medical schools | Risk factors | Methicillin | Cell growth | Red blood cells | Pseudomonas aeruginosa | Bacteria | Biocompatibility | Pharmaceutical industry | Aerogenes | Staphylococcus infections | Antimicrobial agents | Bacteriology | Studies | Chemotherapy | Hospitals | Infectious diseases | Biofilms | Antibiotics | Hepatocytes | Minimum inhibitory concentration | Index Medicus
Journal Article