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Immunity, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 722 - 732
CD4 T cell differentiation is regulated by specialized antigen-presenting cells. Dendritic cells (DCs) produce cytokines that promote naive CD4 T cell... 
DUST MITE ALLERGEN | IN-VIVO | LYMPH-NODES | CONTACT HYPERSENSITIVITY | TYPE-2 IMMUNITY | DIFFERENTIATION | SPECIFICATION | IMMUNOLOGY | EXPRESSION | T-CELLS | INTERFERON REGULATORY FACTOR-4 | Th1 Cells - pathology | Ovalbumin - immunology | Coculture Techniques | Dendritic Cells - immunology | Dendritic Cells - pathology | Th2 Cells - immunology | Nippostrongylus - immunology | Th1 Cells - immunology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Th2 Cells - parasitology | Allergens - immunology | Strongylida Infections - parasitology | Bone Marrow Cells - immunology | Strongylida Infections - immunology | Cell Differentiation | T-Lymphocytes, Regulatory - parasitology | Th2 Cells - pathology | Dendritic Cells - parasitology | Signal Transduction | Bone Marrow Cells - cytology | Gene Expression Regulation | Interferon Regulatory Factors - genetics | Mice, Transgenic | Strongylida Infections - pathology | Bone Marrow Cells - parasitology | Interferon Regulatory Factors - immunology | Animals | Th1 Cells - parasitology | Mice | Immunity, Cellular | Allergens | Dendritic cells | Proteases | Developmental biology | Biological response modifiers | T cells | Public health | Flow cytometry | Transcription factors | Cytokines | Lymphocytes | Rodents | T cell receptors | Infections | Genomes | Gene expression | Deoxyribonucleic acid--DNA | Immune system
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 27, pp. 12204 - 12209
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 2011, Volume 35, Issue 12, pp. 1376 - 1387
Interferons (IFNs) are the hallmark of the vertebrate antiviral system. Two of the three IFN families identified in higher vertebrates are now known to be... 
Antiviral defence | Evolution | Interferon | Interferon receptor | Teleost fish | DOUBLE-STRANDED-RNA | RAINBOW-TROUT | ZEBRAFISH DANIO-RERIO | IMMUNOLOGY | TOLL-LIKE RECEPTOR-3 | CARP CYPRINUS-CARPIO | ZOOLOGY | CARASSIUS-AURATUS L | SALMON SALMO-SALAR | TROUT ONCORHYNCHUS-MYKISS | NF-KAPPA-B | REGULATORY FACTOR-I | Receptors, Pattern Recognition - immunology | Virus Diseases - virology | STAT Transcription Factors - immunology | Phylogeny | Interferon Type I - immunology | Fishes - immunology | Fish Proteins - genetics | Signal Transduction - immunology | Fish Diseases - immunology | Janus Kinases - immunology | Interferon-gamma - genetics | Receptors, Interferon - genetics | Fishes - genetics | Virus Diseases - immunology | Fish Proteins - immunology | Janus Kinases - genetics | Gene Expression Regulation - immunology | Suppressor of Cytokine Signaling Proteins - immunology | Interferon Type I - classification | Suppressor of Cytokine Signaling Proteins - genetics | Viruses - immunology | Interferon-gamma - classification | Biological Evolution | STAT Transcription Factors - genetics | Animals | Fish Diseases - virology | Receptors, Interferon - immunology | Interferon-gamma - immunology | Interferon Type I - genetics | Receptors, Pattern Recognition - genetics | Cysteine | Immunoglobulins | Nitric oxide | Genes | Interferon beta | Melanoma | Physiological aspects | Genetics | Biological response modifiers
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 387 - 399.e5
The DNA-mediated innate immune response underpins anti-microbial defenses and certain autoimmune diseases. Here we used immunoprecipitation, mass spectrometry,... 
HEXIM1 | DNA-PK | innate immune response | herpesvirus | paraspeckles | cGAS | NEAT1 | interferon stimulatory DNA | DEFENSE | PROTEIN | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | SENSOR | POLYMERASE-II | 7SK RNA | BINDING | GMP-AMP SYNTHASE | P-TEFB | CELL BIOLOGY | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Octamer Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Herpesvirus 8, Human - immunology | RNA, Long Noncoding - immunology | PTB-Associated Splicing Factor - genetics | RNA Interference | Calcium-Binding Proteins - immunology | Octamer Transcription Factors - genetics | Nucleotidyltransferases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Signal Transduction | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | PTB-Associated Splicing Factor - metabolism | Nuclear Matrix-Associated Proteins - metabolism | PTB-Associated Splicing Factor - immunology | DNA - metabolism | Host-Pathogen Interactions | Nuclear Matrix-Associated Proteins - genetics | HeLa Cells | RNA-Binding Proteins - metabolism | Calcium-Binding Proteins - genetics | RNA-Binding Proteins - genetics | Multiprotein Complexes | Human Umbilical Vein Endothelial Cells - immunology | Intracellular Signaling Peptides and Proteins - immunology | Human Umbilical Vein Endothelial Cells - virology | Interferon Regulatory Factor-3 - genetics | Ku Autoantigen - genetics | Transfection | HEK293 Cells | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Octamer Transcription Factors - metabolism | Interferon Regulatory Factor-3 - immunology | Calcium-Binding Proteins - metabolism | DNA - immunology | Nuclear Matrix-Associated Proteins - immunology | Ku Autoantigen - immunology | Membrane Proteins - immunology | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | RNA, Long Noncoding - genetics | Immunity, Innate | Nuclear Proteins - immunology | DNA - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Nucleotidyltransferases - immunology | RNA, Long Noncoding - metabolism | RNA sequencing | Immune response | RNA | DNA | Genetic research | Interferon | Biological response modifiers | Mass spectrometry | Human Umbilical Vein Endothelial Cells | Nuclear Matrix-Associated Proteins | Herpesvirus 8, Human | RNA-Binding Proteins | Life Sciences | Interferon Regulatory Factor-3 | Genetics | Calcium-Binding Proteins | Intracellular Signaling Peptides and Proteins | PTB-Associated Splicing Factor | Nuclear Proteins | Membrane Proteins | Nucleotidyltransferases | Ku Autoantigen | Octamer Transcription Factors | RNA, Long Noncoding
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 25, pp. 10240 - 10245
Journal Article
Immunity, ISSN 1074-7613, 08/2014, Volume 41, Issue 2, pp. 244 - 256
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 514 - 527
Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate immunity are poorly understood. Here we show that IL-21 induced apoptosis... 
NKT CELLS | HOMEOSTASIS | FOLLICULAR-HELPER-CELLS | HUMAN B-CELLS | STEADY-STATE | INTERLEUKIN-21 | DIFFERENTIATION | IMMUNOLOGY | IMMUNE TOLERANCE | T-CELLS | NEGATIVE REGULATOR | Natural Killer T-Cells - drug effects | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Dendritic Cells - immunology | STAT5 Transcription Factor - immunology | Receptors, Interleukin-21 - genetics | Interferon-gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Gene Expression - immunology | STAT3 Transcription Factor - genetics | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | DNA, Intergenic - genetics | Protein Binding - immunology | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Galactosylceramides - immunology | Mice | STAT3 Transcription Factor - immunology | Gene Expression - drug effects | Galactosylceramides - pharmacology | DNA-Binding Proteins - deficiency | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-21 - deficiency | Flow Cytometry | Bcl-2-Like Protein 11 | Natural Killer T-Cells - metabolism | DNA, Intergenic - metabolism | Interleukins - immunology | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Dendritic Cells - drug effects | Membrane Proteins - metabolism | Interleukins - pharmacology | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | Receptors, Interleukin-21 - immunology | Mice, Inbred C57BL | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Animals | Apoptosis - immunology | Interferon-gamma - immunology | CD4-Positive T-Lymphocytes - drug effects | DNA, Intergenic - immunology | Natural Killer T-Cells - immunology | Interleukins | Dendritic cells | Analysis | Genomics | Macrophage colony stimulating factor | Biological response modifiers | T cells | Apoptosis | Cytokines | Genes | Genomes | Kinases | Binding sites | Deoxyribonucleic acid--DNA | apoptosis | dendritic cells | GM-CSF | IL-21
Journal Article