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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2010, Volume 397, Issue 2, pp. 350 - 354
Proteins are folded properly in the endoplasmic reticulum (ER). Various stress such as hypoxia, ischemia and starvation interfere with the ER function, causing... 
ER stress | Environmental UVB | HaCaT cells | ATF6 | CELLS | INDUCED PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-PROTEIN | JNK1 | INDUCTION | BIOPHYSICS | ENDOPLASMIC-RETICULUM | TRANSCRIPTION FACTOR | EXPRESSION | TRANSMEMBRANE PROTEIN | Membrane Proteins - radiation effects | Keratinocytes - radiation effects | eIF-2 Kinase - metabolism | Humans | Stress, Physiological | Endoplasmic Reticulum - metabolism | X-Box Binding Protein 1 | Endoribonucleases - radiation effects | DNA-Binding Proteins - metabolism | Ubiquitination | Cell Nucleus - metabolism | Ultraviolet Rays | Cell Nucleus - radiation effects | Protein-Serine-Threonine Kinases - radiation effects | Membrane Proteins - metabolism | Signal Transduction - radiation effects | Protein Folding - radiation effects | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Transcription Factors - radiation effects | DNA-Binding Proteins - radiation effects | Endoribonucleases - metabolism | Environmental Exposure | Activating Transcription Factor 6 - radiation effects | Regulatory Factor X Transcription Factors | Transcription Factors - metabolism | Activating Transcription Factor 6 - metabolism | Keratinocytes - metabolism | Active Transport, Cell Nucleus - drug effects | Endoplasmic Reticulum - radiation effects | Ubiquitin | Stress (Psychology) | Index Medicus | APOPTOSIS | IRRADIATION | ENDOPLASMIC RETICULUM | RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS | ANOXIA | ULTRAVIOLET RADIATION | BIOLOGICAL RADIATION EFFECTS | ISCHEMIA | RADIATION DOSES | PROTEINS
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 05/2018, Volume 101, Issue 1, pp. 74 - 87
Ablative hypofractionated radiation therapy (AHFRT) presents a therapeutic advantage compared with conventional fractionated radiation therapy (CFRT) for... 
LINEAR-QUADRATIC MODEL | LUNG-CANCER | ACTIVATION | MELANOMA | ONCOLOGY | RADIOBIOLOGY | REGULATORY T-CELLS | TUMOR | RADIOTHERAPY | EXPRESSION | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Tumor Burden - radiation effects | Melanoma, Experimental - radiotherapy | Vascular Endothelial Growth Factor A - radiation effects | Carcinoma, Lewis Lung - immunology | B7-H1 Antigen - therapeutic use | Melanoma, Experimental - metabolism | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Radiation Dose Hypofractionation | Vascular Endothelial Growth Factor A - metabolism | Myeloid-Derived Suppressor Cells - radiation effects | Vascular Endothelial Growth Factor A - antagonists & inhibitors | CD8-Positive T-Lymphocytes - radiation effects | Flow Cytometry | Melanoma, Experimental - immunology | Receptors, Vascular Endothelial Growth Factor - metabolism | Myeloid-Derived Suppressor Cells - cytology | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Carcinoma, Lewis Lung - radiotherapy | Immunocompetence | Immunotherapy, Adoptive - methods | Mice, Inbred C57BL | Melanoma, Experimental - pathology | Programmed Cell Death 1 Receptor - metabolism | Random Allocation | Carcinoma, Lewis Lung - metabolism | Animals | Receptors, Vascular Endothelial Growth Factor - radiation effects | Dose Fractionation, Radiation | Mice, Nude | Carcinoma, Lewis Lung - pathology | Combined Modality Therapy - methods | Mice | Mice, Inbred BALB C | Immunocompromised Host | Programmed Cell Death 1 Receptor - immunology | Relative Biological Effectiveness | Lymphocytes, Tumor-Infiltrating - radiation effects | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, pp. e0159998 - e0159998
Recent research found that Tiron was an effective antioxidant that could act as the intracellular reactive oxygen species (ROS) scavenger or alleviate the... 
IRRADIATION | OXIDATIVE STRESS | HUMAN SKIN | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MECHANISMS | SODIUM 4,5-DIHYDROXYBENZENE-1,3-DISULFONATE | INDUCTION | C-JUN | NF-KAPPA-B | PROTEIN-KINASES | Promoter Regions, Genetic - radiation effects | Binding Sites - radiation effects | Humans | Transcriptional Activation - drug effects | Skin Aging - radiation effects | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt - pharmacology | Promoter Regions, Genetic - drug effects | Transcription Factor AP-1 - metabolism | Dermis - drug effects | Cytoprotection - drug effects | Signal Transduction - radiation effects | Dermis - cytology | Matrix Metalloproteinase 1 - genetics | Fibroblasts - metabolism | MAP Kinase Signaling System - radiation effects | Dermis - metabolism | Skin Aging - drug effects | Transcriptional Activation - radiation effects | Cells, Cultured | Dermis - radiation effects | Matrix Metalloproteinase 3 - metabolism | Antioxidants - pharmacology | Ultraviolet Rays - adverse effects | MAP Kinase Signaling System - drug effects | Fibroblasts - radiation effects | Signal Transduction - drug effects | Fibroblasts - drug effects | Transcription Factor AP-1 - radiation effects | Cytoprotection - genetics | Matrix Metalloproteinase 1 - metabolism | Cytoprotection - radiation effects | Matrix Metalloproteinase 3 - genetics | Genetic aspects | Skin | Genetic transcription | RNA | Analysis | Enzyme-linked immunosorbent assay | Oxidative stress | Reactive oxygen species | Transcription factors | Senescence | Oncology | Activation | Matrix metalloproteinase | Kinases | Proteins | Antioxidants | Signal transduction | Consent | Transcription activation | Fibroblasts | Aging | Biocompatibility | Metalloproteinase | Interstitial collagenase | Stromelysin 1 | Wound healing | U.V. radiation | Activator protein 1 | MAP kinase | Gene expression | Medicine | Signaling | Collagen | In vivo methods and tests | Binding sites | Apoptosis | Index Medicus
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 10/2012, Volume 436, Issue 1-2, pp. 545 - 554
A main issue in controlled delivery of biotechnological products from injectable biodegradable microspheres is to preserve their integrity and functional... 
Microspheres | Neuroprotection | Gamma irradiation | Polymeric drug delivery systems | Poly (lactic-co-glycolic acid) | Sterilization | Protein delivery | GDNF (glial cell line-derived neurotrophic factor) | Biological activity | SURVIVAL | LOADED BIODEGRADABLE MICROSPHERES | POLY(D,L-LACTIDE-CO-GLYCOLIDE) MICROSPHERES | ENCAPSULATION | DRUG-RELEASE | RETINAL GANGLION-CELLS | PLGA | PHARMACOLOGY & PHARMACY | SUSTAINED-RELEASE | BIOERODIBLE MICROPARTICLES | Gamma Rays | Lactic Acid - radiation effects | Temperature | Antioxidants - chemistry | Drug Carriers - administration & dosage | Drug Carriers - chemistry | Drug Carriers - radiation effects | Glial Cell Line-Derived Neurotrophic Factor - radiation effects | Retina - cytology | Drug Compounding | Polyglycolic Acid - radiation effects | Recombinant Proteins - radiation effects | Vitamin E - chemistry | Glial Cell Line-Derived Neurotrophic Factor - chemistry | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Cell Survival - drug effects | Vitamin E - radiation effects | Lactic Acid - chemistry | Cells, Cultured | Antioxidants - radiation effects | Recombinant Proteins - chemistry | Glial Cell Line-Derived Neurotrophic Factor - administration & dosage | Recombinant Proteins - administration & dosage | Animals | Polyglycolic Acid - chemistry | Antioxidants - administration & dosage | Vitamin E - administration & dosage | Mice | Drugs | Drug delivery systems | Vehicles | Index Medicus
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 02/2009, Volume 29, Issue 3, pp. 490 - 501
The molecular mechanism underlying circadian rhythmicity within the suprachiasmatic nuclei (SCN) of the hypothalamus has two light-sensitive components, namely... 
Circadian clock | Ontogenesis | Photic entrainment | photic entrainment | PHOTIC REGULATION | BRAIN CLOCK | MPER1 | IMMUNOREACTIVITY | MELANOPSIN | MAMMALIAN CIRCADIAN CLOCK | circadian clock | NEUROSCIENCES | INTRINSIC RHYTHMICITY | PER2 GENES | GANGLION-CELLS | ontogenesis | EXPRESSION | Intracellular Signaling Peptides and Proteins - radiation effects | Rats, Wistar | Male | Intracellular Signaling Peptides and Proteins - metabolism | Light Signal Transduction - genetics | RNA, Messenger - radiation effects | RNA, Messenger - metabolism | Light Signal Transduction - radiation effects | Suprachiasmatic Nucleus - radiation effects | Aging - genetics | Biological Clocks - radiation effects | Light | Cell Cycle Proteins - genetics | Female | Suprachiasmatic Nucleus - metabolism | Neurons - metabolism | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Animals, Newborn | Transcription Factors - radiation effects | Proto-Oncogene Proteins c-fos - radiation effects | Cell Cycle Proteins - metabolism | Cell Cycle Proteins - radiation effects | Proto-Oncogene Proteins c-fos - metabolism | Gene Expression Regulation - physiology | Rats | Aging - radiation effects | Nuclear Proteins - metabolism | Nuclear Proteins - radiation effects | Transcription Factors - genetics | Period Circadian Proteins | Transcription Factors - metabolism | Animals | Biological Clocks - genetics | Gene Expression Regulation - radiation effects | Proto-Oncogene Proteins c-fos - genetics | Neurons - radiation effects | Photic Stimulation | Genetic research | Gene expression | Messenger RNA | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2006, Volume 281, Issue 10, pp. 6413 - 6427
Journal Article