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Molecular Psychiatry, ISSN 1359-4184, 11/2011, Volume 16, Issue 11, pp. 1088 - 1095
Journal Article
Clinical Science, ISSN 0143-5221, 10/2017, Volume 131, Issue 20, pp. 2489 - 2501
Cardiovascular disease (CVD) is the most prevalent cause of mortality among patients with type 1 or type 2 diabetes, due to accelerated atherosclerosis. Recent... 
MEDICINE, RESEARCH & EXPERIMENTAL | OBESITY | PTP1B | HIGH-FAT DIET | INFLAMMATION | ENDOTHELIAL-CELLS | HEART-FAILURE | MACROPHAGE | GENE DELETION | KNOCKOUT MICE | INSULIN SENSITIVITY | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Atherosclerosis - genetics | Cholesterol - blood | Homeostasis | Male | Enzyme Inhibitors - administration & dosage | Atherosclerosis - enzymology | Time Factors | Diet, High-Fat | Receptors, LDL - deficiency | Aortic Diseases - prevention & control | Aortic Diseases - enzymology | Chemokine CCL2 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Aorta - enzymology | Spermine - analogs & derivatives | Aortic Diseases - pathology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Genetic Predisposition to Disease | Drug Administration Schedule | Spermine - administration & dosage | Aorta - drug effects | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors | Biomarkers - blood | Plaque, Atherosclerotic | Mice, Knockout | Aorta - pathology | Blood Glucose - drug effects | Aortic Diseases - genetics | Phenotype | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism | Animals | Signal Transduction - drug effects | Weight Loss | Triglycerides - blood | Cholestanes - administration & dosage | Blood Glucose - metabolism | Atherosclerosis - prevention & control
Journal Article
FEBS Journal, ISSN 1742-464X, 10/2010, Volume 277, Issue 19, pp. 3904 - 3923
The expression of proteoglycans (PGs), essential macromolecules of the tumor microenvironment, is markedly altered during malignant transformation and tumor... 
proteoglycans | lumican | decorin | syndecans | molecular targeting | perlecan | versican | cancer | serglycin | glypicans | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIGH SYNDECAN-1 EXPRESSION | BEHMEL OVERGROWTH SYNDROME | GROWTH-FACTOR RECEPTOR | BREAST-CANCER CELLS | STROMAL VERSICAN EXPRESSION | LEUCINE-RICH PROTEOGLYCANS | IN-VIVO | SQUAMOUS-CELL CARCINOMA | HEPARAN-SULFATE PROTEOGLYCANS | TUMOR-GROWTH | Decorin | Prognosis | Cartilage - pathology | Humans | Aggrecans - therapeutic use | Proteoglycans - drug effects | Lectins, C-Type - metabolism | Versicans - genetics | Neoplasms - genetics | Cell Division | Glioma - pathology | Neovascularization, Pathologic - physiopathology | Neoplasms - physiopathology | Extracellular Matrix Proteins - metabolism | Chondroitin Sulfate Proteoglycans - metabolism | Proteoglycans - metabolism | Aggrecans - metabolism | Disease Progression | Neoplasms - drug therapy | Nerve Tissue Proteins - metabolism | Proteoglycans - therapeutic use | Brevican | Proteoglycans - physiology | Agrin - physiology | Hyaluronic Acid - metabolism | Biomarkers | Inflammation - genetics | Glioma - physiopathology | Neoplasms - pathology | Versicans - therapeutic use | Proteoglycans - genetics | Proteases | Oncology, Experimental | Physiological aspects | Medical law | Development and progression | Research | Cancer | Gene expression | Pharmacology | Tumors | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICINE | MEDICIN
Journal Article
eLife, ISSN 2050-084X, 05/2014, Volume 3, Issue 3, p. e02523
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2011, Volume 286, Issue 8, pp. 6433 - 6448
Phosphoinositide-dependent kinase 1 (PDK1) is a critical activator of multiple prosurvival and oncogenic protein kinases and has garnered considerable interest... 
SIGNAL-TRANSDUCTION | AGC KINASES | STRUCTURAL MECHANISM | SMALL-MOLECULE INHIBITORS | PHOSPHATIDYLINOSITOL 3-KINASE | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | 3-PHOSPHOINOSITIDE-DEPENDENT KINASE-1 | TUMOR-SUPPRESSOR | HUMAN BREAST-CANCER | Allosteric Regulation - drug effects | Allosteric Regulation - genetics | Drug Screening Assays, Antitumor - methods | Humans | Catalytic Domain - genetics | Protein-Serine-Threonine Kinases - genetics | Neoplasms - enzymology | Crystallography, X-Ray | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Neoplasms - drug therapy | Phosphorylation - genetics | Protein Kinase Inhibitors - chemistry | Animals | Neoplasms - genetics | Dogs | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | BENCHMARKS | NEOPLASMS | BASIC BIOLOGICAL SCIENCES | PHOSPHORYLATION | COLONY FORMATION | TUMOR CELLS | 60 APPLIED LIFE SCIENCES | TISSUE CULTURES | GENETICS | IN VITRO | CONVERGENCE | PHOSPHOTRANSFERASES | PROTEINS | Cancer Therapy | Enzyme Inhibitors | Biomarker | Signal Transduction | Protein Kinases | X-ray Crystallography | Allosteric Regulation | Phosphatidylinositol 3-Kinase | Phosphatidylinositol-dependent Kinase-1 (PDK1) | Protein-Drug Interactions | AKT PKB
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 11/2011, Volume 339, Issue 2, pp. 555 - 566
Journal Article
Indian Journal of Pharmacology, ISSN 0253-7613, 11/2018, Volume 50, Issue 6, pp. 299 - 301
Journal Article
Cancer Letters, ISSN 0304-3835, 09/2017, Volume 404, pp. 29 - 36
Journal Article