X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (20850) 20850
Newspaper Article (514) 514
Book Chapter (76) 76
Magazine Article (9) 9
Book / eBook (6) 6
Dissertation (3) 3
Web Resource (3) 3
Book Review (1) 1
Conference Proceeding (1) 1
Newsletter (1) 1
Publication (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (17061) 17061
female (8825) 8825
biomarkers (8110) 8110
male (8094) 8094
oncology (6231) 6231
middle aged (6023) 6023
animals (5558) 5558
cancer (4833) 4833
aged (4785) 4785
adult (4435) 4435
prognosis (3940) 3940
expression (3602) 3602
biomarkers, tumor - metabolism (3388) 3388
biomarkers - blood (3122) 3122
inflammation (2797) 2797
gene expression (2794) 2794
proteins (2794) 2794
research (2741) 2741
mice (2720) 2720
tumors (2645) 2645
biomarkers, tumor - genetics (2631) 2631
apoptosis (2487) 2487
cell line, tumor (2419) 2419
analysis (2391) 2391
biomarkers - metabolism (2274) 2274
treatment outcome (2264) 2264
metastasis (2225) 2225
care and treatment (2187) 2187
cytokines (2060) 2060
health aspects (1956) 1956
cell biology (1943) 1943
aged, 80 and over (1846) 1846
patients (1845) 1845
medicine (1773) 1773
immunohistochemistry (1772) 1772
chemotherapy (1736) 1736
signal transduction (1711) 1711
research article (1704) 1704
risk factors (1681) 1681
breast cancer (1675) 1675
biomarker (1647) 1647
antineoplastic agents - therapeutic use (1539) 1539
development and progression (1537) 1537
studies (1511) 1511
diagnosis (1481) 1481
genetic aspects (1476) 1476
mutation (1470) 1470
immunology (1468) 1468
gene expression regulation, neoplastic (1463) 1463
medicine & public health (1446) 1446
pathology (1430) 1430
kinases (1426) 1426
cell proliferation (1406) 1406
multidisciplinary sciences (1385) 1385
biochemistry & molecular biology (1373) 1373
cells (1360) 1360
survival (1341) 1341
medical research (1323) 1323
activation (1294) 1294
review (1269) 1269
cancer therapies (1256) 1256
medical prognosis (1256) 1256
neoplasm staging (1194) 1194
therapy (1190) 1190
antineoplastic agents - pharmacology (1186) 1186
disease (1178) 1178
disease progression (1156) 1156
biomarkers, tumor - analysis (1144) 1144
physiological aspects (1144) 1144
science (1135) 1135
clinical trials (1121) 1121
medicine, research & experimental (1116) 1116
biomarkers, tumor - blood (1113) 1113
surgery (1084) 1084
young adult (1063) 1063
genes (1049) 1049
pharmacology & pharmacy (1045) 1045
gene expression profiling (1027) 1027
biomarkers, tumor (1024) 1024
c-reactive protein (1015) 1015
biological markers (1002) 1002
time factors (999) 999
biology (997) 997
angiogenesis (995) 995
mortality (992) 992
carcinoma (981) 981
gene-expression (981) 981
case-control studies (979) 979
immunotherapy (977) 977
growth (968) 968
breast-cancer (964) 964
rodents (964) 964
disease models, animal (952) 952
molecular targeted therapy (949) 949
predictive value of tests (927) 927
follow-up studies (921) 921
rats (905) 905
prostate cancer (904) 904
signal transduction - drug effects (897) 897
tumor cells, cultured (877) 877
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (21244) 21244
Japanese (72) 72
German (58) 58
French (54) 54
Spanish (29) 29
Russian (20) 20
Hungarian (11) 11
Polish (9) 9
Chinese (8) 8
Italian (4) 4
Portuguese (4) 4
Korean (3) 3
Swedish (2) 2
Turkish (2) 2
Arabic (1) 1
Czech (1) 1
Danish (1) 1
Dutch (1) 1
Finnish (1) 1
Norwegian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature (London), ISSN 1476-4687, 2015, Volume 527, Issue 7578, pp. 329 - 335
.... Here we demonstrate that exosomes from mouse and human lung-, liver-and brain-tropic tumour cells fuse preferentially with resident cells at their predicted destination, namely lung fibroblasts... 
CELLS | BONE METASTASES | VESICLES | BREAST-CANCER METASTASIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | NICHE | MICROVESICLES | PROTEINS | PROTEOMICS | Exosomes - metabolism | Tropism | Phosphorylation | Epithelial Cells - metabolism | Receptors, Vitronectin - antagonists & inhibitors | Humans | Lung - cytology | Integrin beta4 - metabolism | Integrins - metabolism | Brain - metabolism | Integrin alpha6beta1 - metabolism | S100 Proteins - genetics | Neoplasm Metastasis - prevention & control | Female | Kupffer Cells - metabolism | Lung - metabolism | Receptors, Vitronectin - metabolism | Epithelial Cells - cytology | Integrin alpha6beta4 - metabolism | Fibroblasts - metabolism | Biomarkers - metabolism | Brain - cytology | Kupffer Cells - cytology | Endothelial Cells - metabolism | Liver - metabolism | Mice, Inbred C57BL | Integrin alpha6beta4 - antagonists & inhibitors | Organ Specificity | Animals | Endothelial Cells - cytology | Neoplasm Metastasis - pathology | Cell Line, Tumor | Integrin beta Chains - metabolism | Fibroblasts - cytology | Liver - cytology | Mice | Genes, src | Integrins - antagonists & inhibitors | Complications and side effects | Development and progression | Cell organelles | Metastasis | Health aspects | Integrins | Tumors | Studies | Microscopy | Liver | Melanoma | Fibroblasts | Breast cancer | Chemokines | mechanisms of disease | cancer microenvironment | BASIC BIOLOGICAL SCIENCES | metastasis | 60 APPLIED LIFE SCIENCES
Journal Article
Pancreas, ISSN 0885-3177, 04/2013, Volume 42, Issue 3, pp. 411 - 421
Objectives: Pancreatic endocrine tumors (PETs) share numerous features with gastrointestinal neuroendocrine (carcinoid) tumors... 
Pancreatic endocrine tumors | Molecular analysis | pancreatic endocrine tumors | GEFITINIB | NEUROENDOCRINE TUMORS | GROWTH-FACTOR-RECEPTOR | KRAS MUTATION | SENSITIVITY | EGFR | CELL LUNG-CANCER | COLORECTAL-CANCER | GASTROENTEROLOGY & HEPATOLOGY | molecular analysis | GENE COPY NUMBER | CLINICAL-RESPONSE | Immunohistochemistry | Receptor, Epidermal Growth Factor - genetics | Receptor, IGF Type 1 - metabolism | Proto-Oncogene Proteins p21(ras) | Pyrazoles - therapeutic use | Receptor, IGF Type 1 - antagonists & inhibitors | Pancreatic Neoplasms - metabolism | Receptor, ErbB-2 - genetics | Humans | Carcinoid Tumor - metabolism | Biomarkers, Tumor - metabolism | Receptors, Somatostatin - antagonists & inhibitors | Receptor, ErbB-2 - antagonists & inhibitors | Receptors, Somatostatin - metabolism | Imidazoles - therapeutic use | Protein-Serine-Threonine Kinases - metabolism | Cell Survival - drug effects | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Carcinoid Tumor - drug therapy | ras Proteins - antagonists & inhibitors | In Situ Hybridization, Fluorescence | Carcinoid Tumor - genetics | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Drug Therapy - methods | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Cell Line, Tumor | HSP90 Heat-Shock Proteins - metabolism | Biomarkers, Tumor - genetics | Mutation | Benzoquinones - therapeutic use | Indazoles - therapeutic use | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | ras Proteins - genetics | Triazines - therapeutic use | Receptor, ErbB-2 - metabolism | ras Proteins - metabolism | Proto-Oncogene Proteins c-kit - metabolism | Proto-Oncogene Proteins c-kit - antagonists & inhibitors | Pancreatic Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - metabolism | Receptor, Platelet-Derived Growth Factor alpha - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Proto-Oncogene Proteins c-kit - genetics | Lactams, Macrocyclic - therapeutic use | Biomarkers, Tumor - antagonists & inhibitors | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Pancreatic Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Receptors, Transforming Growth Factor beta - metabolism | Protein Kinase Inhibitors - therapeutic use | Receptor, Platelet-Derived Growth Factor alpha - genetics | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 539, Issue 7627, pp. 107 - 111
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2017, Volume 377, Issue 25, pp. 2500 - 2501
Journal Article
Journal Article
Nature immunology, ISSN 1529-2916, 2015, Volume 16, Issue 11, pp. 1174 - 1184
Human regulatory T cells (T-reg cells) that develop from conventional T cells (T-conv cells) cells) following suboptimal stimulation via the T cell antigen... 
ACTIVATION | ALPHA-ENOLASE | TOLERANCE | IN-VIVO | EFFECTOR FUNCTION | EXPANSION | GENERATION | DIFFERENTIATION | IMMUNOLOGY | IDENTIFICATION | MTOR | Autoimmunity | T-Lymphocytes, Regulatory - metabolism | T-Lymphocytes, Regulatory - classification | Alternative Splicing | Tumor Suppressor Proteins - antagonists & inhibitors | Exons | Humans | Middle Aged | Male | Phosphopyruvate Hydratase - metabolism | CD4-Positive T-Lymphocytes - classification | RNA, Messenger - metabolism | Case-Control Studies | Gene Knockdown Techniques | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | DNA-Binding Proteins - metabolism | Genetic Variation | Glycolysis - genetics | Young Adult | Signal Transduction - immunology | Phosphopyruvate Hydratase - genetics | Forkhead Transcription Factors - metabolism | Tumor Suppressor Proteins - genetics | Biomarkers, Tumor - metabolism | Adult | Female | Forkhead Transcription Factors - antagonists & inhibitors | Biomarkers, Tumor - antagonists & inhibitors | Fatty Acids - metabolism | Multiple Sclerosis, Relapsing-Remitting - metabolism | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Multiple Sclerosis, Relapsing-Remitting - immunology | Oxidation-Reduction | Receptors, Antigen, T-Cell - metabolism | RNA, Messenger - genetics | CD4-Positive T-Lymphocytes - metabolism | Metabolome | Phosphopyruvate Hydratase - antagonists & inhibitors | DNA-Binding Proteins - genetics | Forkhead Transcription Factors - genetics | Multiple Sclerosis, Relapsing-Remitting - genetics | Biomarkers, Tumor - genetics | In Vitro Techniques | Physiological aspects | Glycolysis | Genetic aspects | Research | T cells
Journal Article
Oncogene, ISSN 0950-9232, 02/2012, Volume 31, Issue 6, pp. 752 - 763
.... We hypothesized that reactivation of p53 by inhibition of its negative regulator MDM2, using the MDM2-p53 antagonists Nutlin-3 and MI-63, will result in p53-mediated growth arrest and apoptosis... 
neuroblastoma | apoptosis | MYCN | growth inhibition | MDM2-p53 antagonists | P53-DEPENDENT APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | P53/MDM2/P14(ARF) PATHWAY | DIRECT TRANSCRIPTIONAL TARGET | CELL-DEATH | CELL BIOLOGY | G ARREST | AMPLIFICATION | ONCOLOGY | P53 GENE-MUTATIONS | IN-VIVO | GENETICS & HEREDITY | N-MYC | Caspase 7 - metabolism | Oncogene Proteins - genetics | Proto-Oncogene Proteins c-mdm2 - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Drug Resistance, Neoplasm | Tumor Suppressor Protein p53 - genetics | Dose-Response Relationship, Drug | Flow Cytometry | RNA Interference | Indoles - pharmacology | N-Myc Proto-Oncogene Protein | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-mdm2 - antagonists & inhibitors | Proto-Oncogene Proteins c-mdm2 - metabolism | Tetracycline - pharmacology | Oncogene Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Imidazoles - pharmacology | Piperazines - pharmacology | Blotting, Western | Signal Transduction - drug effects | Models, Biological | Cell Line, Tumor | Cell Proliferation - drug effects | Mutation | Tumor Suppressor Protein p14ARF - genetics | Cell Cycle - drug effects | Tumor Suppressor Protein p14ARF - metabolism | Spiro Compounds - pharmacology | Gene mutations | Physiological aspects | Development and progression | Research | Neuroblastoma | Tumor proteins | Apoptosis | Proteins | Nervous system | Cell growth | Gene expression | Cancer | MDM2 protein | Prognosis | Risk groups | Transcription | biomarkers | Antagonists | Caspase-3 | Neuroblastoma cells | p53 protein | p14ARF protein
Journal Article
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 5/2016, Volume 43, Issue 5, pp. 964 - 973
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2017, Volume 357, Issue 6349, pp. 409 - 413
...). We have now expanded this study to evaluate the efficacy of PD-1 blockade in patients with advanced mismatch repair-deficient cancers across 12 different tumor types... 
CELL LUNG-CANCER | SURVIVAL | COLORECTAL CARCINOMAS | RECEIVING NIVOLUMAB | IMMUNOTHERAPY | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | NEOANTIGENS | CHECKPOINT BLOCKADE | LYMPHOCYTES | Neoplastic Syndromes, Hereditary - immunology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Neoplastic Syndromes, Hereditary - mortality | Young Adult | Colorectal Neoplasms - therapy | Brain Neoplasms - immunology | DNA Mismatch Repair | Aged, 80 and over | Adult | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Biomarkers, Tumor - antagonists & inhibitors | Colorectal Neoplasms - mortality | Antibodies, Monoclonal, Humanized - therapeutic use | Antigens, Neoplasm - immunology | Brain Neoplasms - genetics | Disease-Free Survival | Colorectal Neoplasms - immunology | Cell Cycle Checkpoints - drug effects | Brain Neoplasms - therapy | Neoplastic Syndromes, Hereditary - therapy | T-Lymphocytes - immunology | Aged | Mutation | Programmed Cell Death 1 Receptor - immunology | Colorectal cancer | Genetic aspects | Nucleotide sequencing | Health aspects | DNA repair | Methods | Tumors | DNA sequencing | Yeast | PD-1 protein | Antibodies | Clinical trials | Genomes | Functional analysis | Lymphocytes T | Patients | Survival | Colon cancer | Immune checkpoint | Immunotherapy | Mismatch repair | Pancreatic cancer | Biomarkers | Colon | Solid tumors | Genetic recombination | Repair | Cancer | Apoptosis
Journal Article
Cancer discovery, ISSN 2159-8290, 2016, Volume 6, Issue 8, pp. 827 - 837
Journal Article