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Diabetes, Obesity and Metabolism, ISSN 1462-8902, 12/2015, Volume 17, Issue 12, pp. 1133 - 1141
Aim: To test the hypothesis that a 'basal plus' regimen-adding once-daily main-meal fast-acting insulin to basal insulin once daily-would be non-inferior to... 
clinical trial | phase | type 2 diabetes | insulin therapy | Type 2 diabetes | Clinical trial | Insulin therapy | Phase IV | METFORMIN | MANAGEMENT | EUROQOL | ANALOG | phase IV | TO-TARGET TRIAL | MELLITUS | TREATMENT SATISFACTION QUESTIONNAIRE | PREMIXED INSULIN | ORAL-THERAPY | ENDOCRINOLOGY & METABOLISM | QUALITY-OF-LIFE | Glycated Hemoglobin A - analysis | Insulin Aspart - therapeutic use | Hypoglycemia - epidemiology | Biphasic Insulins - adverse effects | Humans | Middle Aged | Male | Patient Dropouts | Incidence | Hypoglycemia - prevention & control | Insulin Glargine - administration & dosage | Drug Therapy, Combination - adverse effects | Insulin Aspart - administration & dosage | Hypoglycemic Agents - administration & dosage | Female | Insulin - analogs & derivatives | Hypoglycemia - chemically induced | Hypoglycemic Agents - therapeutic use | Insulin, Isophane - administration & dosage | Hyperglycemia - prevention & control | Insulin Glargine - adverse effects | Drug Administration Schedule | Insulin Glargine - therapeutic use | Insulin - administration & dosage | Australia - epidemiology | Diabetes Mellitus, Type 2 - blood | Insulin, Isophane - therapeutic use | Biphasic Insulins - therapeutic use | Insulin, Isophane - adverse effects | Intention to Treat Analysis | Blood Glucose Self-Monitoring | Quality of Life | Aged | Biphasic Insulins - administration & dosage | Hyperglycemia - epidemiology | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Insulin Aspart - adverse effects | United Kingdom - epidemiology | Drug Combinations | Insulin - therapeutic use | Hockey | Analysis | Clinical trials | Hemoglobin | Adults | Glucose | Insulin | Dextrose | Hyperglycemia | Diabetes | Optimization | Questionnaires | Index Medicus
Journal Article
Journal Article
Journal Article
Diabetic Medicine, ISSN 0742-3071, 04/2016, Volume 33, Issue 4, pp. 497 - 505
Insulin degludec/insulin aspart (IDegAsp) is the first soluble co‐formulation that combines two insulin analogues. It provides effective basal and prandial... 
TO-TARGET TRIAL | MELLITUS | INJECTION | ENDOCRINOLOGY & METABOLISM | BASAL | Glycated Hemoglobin A - analysis | Insulin Aspart - therapeutic use | Hypoglycemia - epidemiology | Biphasic Insulins - adverse effects | Humans | Middle Aged | Insulin, Long-Acting - chemistry | Male | Risk | Hypoglycemia - prevention & control | Insulin Aspart - administration & dosage | Hypoglycemic Agents - administration & dosage | Hypoglycemia - physiopathology | Female | Hypoglycemia - chemically induced | Meals | Hypoglycemic Agents - therapeutic use | Insulin, Isophane - administration & dosage | Severity of Illness Index | Hyperglycemia - prevention & control | Blood Glucose - analysis | Drug Administration Schedule | Solubility | Hypoglycemic Agents - chemistry | Insulin, Long-Acting - adverse effects | Diabetes Mellitus, Type 2 - blood | Insulin, Isophane - therapeutic use | Insulin, Long-Acting - administration & dosage | Biphasic Insulins - therapeutic use | Insulin, Isophane - adverse effects | Insulin, Long-Acting - therapeutic use | Blood Glucose Self-Monitoring | Aged | Biphasic Insulins - administration & dosage | Diabetes Mellitus, Type 2 - drug therapy | Drug Monitoring | Hypoglycemic Agents - adverse effects | Insulin Aspart - adverse effects | Drug Combinations | Plasma | Fasting | Glucose | Diabetes | Hypoglycemia | Insulin | Index Medicus | Treatment | Research
Journal Article
Journal Article
Diabetes Care, ISSN 0149-5992, 2014, Volume 37, Issue 8, pp. 2084 - 2090
Journal Article
Journal of Diabetes, ISSN 1753-0393, 03/2017, Volume 9, Issue 3, pp. 243 - 247
背景 : 当前这项研究是一项在既往使用胰岛素治疗控制不佳的日本2型糖尿病受试者中进行的旨在评估德谷胰岛素/门冬胰岛素(IDegAsp)与双相门冬胰岛素30(BIAsp 30)的随机、开放标签、泛亚达标治疗3期试验的亚组分析。 方法 : 入选的受试者(n = 178) 被随机(2:... 
insulin degludec/insulin aspart | nocturnal hypoglycemia | glycemic control | 血糖控制,德谷胰岛素/门冬胰岛素,夜间低血糖 | CO-FORMULATION | GLARGINE | ENDOCRINOLOGY & METABOLISM | STEADY-STATE | PHARMACODYNAMICS | BASAL | Insulin Aspart - therapeutic use | Metformin - therapeutic use | Biphasic Insulins - adverse effects | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Nasopharyngitis - chemically induced | Male | Metformin - adverse effects | Diabetes Mellitus, Type 2 - ethnology | Diabetic Retinopathy - chemically induced | Hypertension - chemically induced | Female | Drug Therapy, Combination | Hypoglycemic Agents - therapeutic use | Drug Administration Schedule | Treatment Outcome | Insulin, Long-Acting - adverse effects | Asian Continental Ancestry Group | Diabetes Mellitus, Type 2 - blood | Insulin, Isophane - therapeutic use | Biphasic Insulins - therapeutic use | Insulin, Isophane - adverse effects | Insulin, Long-Acting - therapeutic use | Aged | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Insulin Aspart - adverse effects | Index Medicus
Journal Article
Diabetes Research and Clinical Practice, ISSN 0168-8227, 2014, Volume 107, Issue 1, pp. 139 - 147
Journal Article
Journal Article
by Liebl, Andreas and Prager, R and Binz, K and Kaiser, M and Bergenstal, R and Gallwitz, B and Biesenbach, G and Ludvik, B and Prager, R and Pusarnig, S and Binz, K and Felix, B and Gerber, P and Loher, A and Golay, A and Aigner, U and Anderten, H and Arnold, J and Austenat, E and Badenhoop, K and Balke, J and Balks, H.-J and Banse, G and Barakat, A and Behnke, T and Bergmann, K and Biermann, U and Böckmann, G.-U and Böhmer, Mi and Braun, M and Daikeler, R and Dehmel, J and Doerwald, H.-J and Ehlenz, K.-A and Eidenmüller, M and Filz, H. Peter and Forchheim, W and Gallwitz, B and Gries, A and Großkopf, J and Grüneberg, M and Günther, R and Güntsch, V and Hanefeld, M and Hartl, J and Hermes, S and Herold-Beifuss, R and Hintze, G and Hirschhäuser, B and Hüning, W and Huppertz, W and Huptas, M and Jung, W and Kerum, G and Klausmann, G and Klein, C and Klör, E and Koch, P and Kohlhas, K and Kosch, C and Krakow, D and Langguth, D and Liebl, A and Lueg, A and Marks, H.-J and Maxeiner, S and Meißner, H.-P and Merker, L and Meyer, U and Milek, K and Mölle, A and Müller, B and Müller, U.-A and Nauck, M and Nossek, L and Oerter, E.-M and Oldenburg, J and Paulus, R and Pein, M and Pfeiffer, A and Reichert, D and Rett, K and Ruhnau, K.-J and Sauter, J and Schmidt, J and Scholz, G and Schories, M and Schulze, J and Schuster, A and Schwinn, G and Segiet, T and Segner, A and Simonsohn, M and Steindorf, J and Sterzing, A and Strache, S and Tosch, R and Treichel, H.-C and Usadel, K.H and Vidal, S and ... and PREFER Study Grp and PREFER Study Group
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 2009, Volume 11, Issue 1, pp. 45 - 52
Journal Article