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Autophagy, ISSN 1554-8635, 10/2014, Volume 6, Issue 2, pp. 256 - 269
Apoptosis and autophagy have been shown to be negatively regulated by pro-survival Bcl-2 proteins. We determined whether the anti-cancer agent celecoxib, alone... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Bcl-2 | ABT-737 | Celecoxib | Autophagy | NSAID | Apoptosis | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Pyrazoles - therapeutic use | Apoptosis - drug effects | Humans | Nitrophenols - metabolism | Piperazines - metabolism | Cell Line, Tumor - drug effects | Phosphatidylinositol 3-Kinases - metabolism | Biphenyl Compounds - metabolism | Biphenyl Compounds - therapeutic use | Autophagy - drug effects | Dose-Response Relationship, Drug | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Colorectal Neoplasms - drug therapy | Nitrophenols - therapeutic use | Cyclooxygenase 2 Inhibitors - therapeutic use | Cyclooxygenase 2 Inhibitors - metabolism | Colorectal Neoplasms - metabolism | bcl-2-Associated X Protein - genetics | Pyrazoles - pharmacology | Cell Survival - drug effects | Cyclooxygenase 2 Inhibitors - pharmacology | bcl-2-Associated X Protein - metabolism | Piperazines - therapeutic use | Pyrazoles - metabolism | Sulfonamides - pharmacology | Piperazines - pharmacology | Phosphatidylinositol 3-Kinases - genetics | Sulfonamides - therapeutic use | Sulfonamides - metabolism | Signal Transduction - physiology | Colorectal Neoplasms - pathology | Proto-Oncogene Proteins c-bcl-2 - genetics | RNA, Small Interfering - metabolism | Index Medicus | apoptosis | autophagy | celecoxib
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2013, Volume 64, pp. 81 - 96
Long-term memory formation is known to be critically dependent upon de novo gene expression in the brain. As a consequence, pharmacological enhancement of the... 
Chromatin | Cognitive enhancer | CREB | Epigenetic | Acetylation | Histone deacetylases | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Embryo, Mammalian - drug effects | Nootropic Agents - metabolism | Neuronal Plasticity - drug effects | Drug Discovery - methods | Male | Neurons - cytology | Biphenyl Compounds - metabolism | Histone Deacetylase Inhibitors - blood | Embryo, Mammalian - metabolism | Prosencephalon - drug effects | Histone Deacetylase Inhibitors - pharmacokinetics | Biphenyl Compounds - pharmacology | Hydrazines - blood | Biphenyl Compounds - blood | Neurons - metabolism | Prosencephalon - metabolism | Neurons - drug effects | Animals, Newborn | Recombinant Proteins - metabolism | Dendrites - drug effects | Dendrites - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Biphenyl Compounds - pharmacokinetics | Hydrazines - pharmacology | Recombinant Proteins - antagonists & inhibitors | Histone Deacetylases - genetics | Mice, Inbred C57BL | Nootropic Agents - pharmacokinetics | Cells, Cultured | Histone Deacetylases - chemistry | Hydrazines - pharmacokinetics | Histone Deacetylases - metabolism | Mice, Transgenic | Nootropic Agents - blood | Nerve Tissue Proteins - genetics | Hydrazines - metabolism | Nerve Tissue Proteins - metabolism | Acetylation - drug effects | Animals | Embryo, Mammalian - cytology | Prosencephalon - cytology | Genes, Reporter - drug effects | Histone Deacetylase Inhibitors - pharmacology | Mice | Histones - metabolism | Histone Deacetylase Inhibitors - metabolism | Nootropic Agents - pharmacology | Genetic transcription | Cognition disorders | Neurons | Genes | Smart drugs and nutrients | Index Medicus | acetylation | histone deacetylases | chromatin | epigenetic
Journal Article
Cancer cell, ISSN 1535-6108, 11/2006, Volume 10, Issue 5, pp. 375 - 388
BCL-2 proteins are critical for cell survival and are overexpressed in many tumors. ABT-737 is a small-molecule BH3 mimetic that exhibits single-agent activity... 
CELLCYCLE | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | bcl-2-Associated X Protein - chemistry | Humans | Leukemia, Myeloid, Acute - metabolism | Nitrophenols - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | Piperazines - metabolism | Neoplasm Proteins - metabolism | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Biphenyl Compounds - metabolism | Biphenyl Compounds - therapeutic use | Recombinant Fusion Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Nitrophenols - therapeutic use | Hematopoietic Stem Cells - physiology | Leukemia, Myeloid, Acute - drug therapy | Proto-Oncogene Proteins c-bcl-2 - chemistry | Dimerization | bcl-2-Associated X Protein - genetics | Protein Structure, Tertiary | Cell Line | bcl-2-Associated X Protein - metabolism | Piperazines - therapeutic use | Animals | Sulfonamides - therapeutic use | Myeloid Cell Leukemia Sequence 1 Protein | Sulfonamides - metabolism | Recombinant Fusion Proteins - genetics | Protein Conformation | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Mice | Apoptosis - physiology | Drug Resistance, Neoplasm - physiology | Proto-Oncogene Proteins c-bcl-2 - genetics | RNA, Small Interfering - metabolism | Proteins | Oncology, Experimental | Lung cancer | Bone marrow | Transplantation | Lymphomas | Research | Hematopoietic stem cells | Cancer | Apoptosis | Index Medicus
Journal Article
Journal Article
BioMed research international, ISSN 2314-6141, 05/2019, Volume 2019, pp. 1 - 15
.... Magnolol, a hydroxylated biphenyl natural compound isolated from , has been extensively documented and shows a range of biological activities... 
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cardiovascular Agents - analysis | Humans | Neuroprotective Agents - analysis | Drugs, Chinese Herbal - pharmacology | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Biphenyl Compounds - metabolism | Biphenyl Compounds - therapeutic use | Drugs, Chinese Herbal - metabolism | Lignans - pharmacology | Lignans - therapeutic use | Magnolia - chemistry | Anti-Inflammatory Agents - analysis | Biphenyl Compounds - pharmacology | Phosphatidylinositol 3-Kinases - drug effects | Biphenyl Compounds - chemistry | Antioxidants - analysis | Drugs, Chinese Herbal - therapeutic use | Medicine, Chinese Traditional | Lignans - chemistry | NF-E2-Related Factor 2 - drug effects | Antineoplastic Agents - analysis | Lignans - metabolism | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Drugs, Chinese Herbal - chemistry | NF-E2-Related Factor 2 - metabolism | NF-kappa B - drug effects | Povidone | Physiological aspects | Health aspects | Neuroprotection | NF-κB protein | Enzymes | Motility | Liver | Traditional Chinese medicine | MAP kinase | AKT protein | Pharmacology | Inflammation | Bioavailability | Metabolism | Chemical compounds | 1-Phosphatidylinositol 3-kinase | Herbal medicine | Toxicology | Pathways | Metabolites | Biphenyl | Index Medicus
Journal Article
Bioscience, biotechnology, and biochemistry, ISSN 1347-6947, 05/2014, Volume 70, Issue 9, pp. 2178 - 2184
Journal Article
Nature (London), ISSN 1476-4687, 06/2007, Volume 447, Issue 7147, pp. 959 - 965
Journal Article
Environmental monitoring and assessment, ISSN 0167-6369, 1/2016, Volume 188, Issue 1, pp. 1 - 14
The aim of this study was to determine the behaviour of strobilurin and carbocyamides commonly used in chemical protection of lettuce depending on carefully... 
LC-MS/MS | Microorganisms | Lettuce | Ecotoxicology | Fungicides | Environment | Ecology | Chronic risk analysis | Environmental Monitoring/Analysis | Atmospheric Protection/Air Quality Control/Air Pollution | Environmental Management | Environmental Sciences & Ecology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Humans | Mucor - metabolism | Methacrylates - chemistry | Biphenyl Compounds - metabolism | Carbamates - chemistry | Pyrimidines - metabolism | Fungicides, Industrial - metabolism | Saccharomyces cerevisiae - metabolism | Pyrazoles - chemistry | Methacrylates - analysis | Lettuce - microbiology | Chromatography, Liquid | Rhodobacteraceae - metabolism | Biphenyl Compounds - chemistry | Niacinamide - analysis | Carbamates - analysis | Hydantoins - metabolism | Tandem Mass Spectrometry - methods | Environmental Monitoring | Lettuce - chemistry | Fungicides, Industrial - analysis | Niacinamide - metabolism | Risk Assessment | Methacrylates - metabolism | Biphenyl Compounds - analysis | Fungicides, Industrial - chemistry | Pesticide Residues - chemistry | Aminoimidazole Carboxamide - analogs & derivatives | Hydantoins - chemistry | Niacinamide - analogs & derivatives | Pesticide Residues - metabolism | Penicillium - metabolism | Lactobacillales - metabolism | Pyrimidines - chemistry | Carbamates - metabolism | Streptomyces - metabolism | Niacinamide - chemistry | Aminoimidazole Carboxamide - chemistry | Pesticide Residues - analysis | Pesticides - metabolism | Aminoimidazole Carboxamide - metabolism | Pyrazoles - analysis | Pyrimidines - analysis | Strobilurins | Aminoimidazole Carboxamide - analysis | Pesticides - analysis | Pyrazoles - metabolism | Aspergillus - metabolism | Pesticides - chemistry | Hydantoins - analysis | Liquid chromatography | Vegetables | Health aspects | Mass spectrometry | Risk assessment | Pathogens | Statistical analysis | Laboratories | Pesticides | Statistical methods | Health risk assessment | Index Medicus | LC-MS
Journal Article