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1. Full Text The discovery of novel LPMO families with a new Hidden Markov model
by Voshol, Gerben P and Vijgenboom, Erik and Punt, Peter J
BMC Research Notes, ISSN 1756-0500, 02/2017, Volume 10, Issue 1, p. 105
Renewable biopolymers, such as cellulose, starch and chitin are highly resistance to enzymatic degradation. Therefore, there is a need to upgrade current... 
Fungi | Hidden Markov model, HMM | Lytic polysaccharide mono-oxygenases | LPMO | Pectin | β-Glucan | Genome mining | Markov Chains | Sea Anemones - genetics | Starch - metabolism | Data Mining | Mixed Function Oxygenases - metabolism | Phylogeny | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Genome, Fungal | Basidiomycota - enzymology | Basidiomycota - classification | Ascomycota - genetics | Chitin - metabolism | Bivalvia - genetics | Oomycetes - enzymology | Oomycetes - classification | Biodegradation, Environmental | Models, Molecular | Ascomycota - enzymology | Fungal Proteins - genetics | Bivalvia - enzymology | Amino Acid Motifs | Hydrolysis | Sequence Alignment | Animals | Sea Anemones - enzymology | Basidiomycota - genetics | Drosophila melanogaster - enzymology | Drosophila Proteins - genetics | Mixed Function Oxygenases - genetics | Ascomycota - classification | Cellulose - metabolism | Fungal Proteins - metabolism | Oomycetes - genetics | Oxidases | Polysaccharides | Usage | Identification and classification | Hidden Markov models
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2. Full Text Evolution of the tyrosinase gene family in bivalve molluscs: Independent expansion of the mantle gene repertoire
by Aguilera, Felipe and McDougall, Carmel and Degnan, Bernard M
Acta Biomaterialia, ISSN 1742-7061, 09/2014, Volume 10, Issue 9, pp. 3855 - 3865
Tyrosinase is a copper-containing enzyme that mediates the hydroxylation of monophenols and oxidation of diphenols to quinones. This enzyme is involved in a... 
Gastropod | Mantle | Shell formation | Bivalve | Tyrosinase | OYSTER CRASSOSTREA-GIGAS | MAXIMUM-LIKELIHOOD | MATERIALS SCIENCE, BIOMATERIALS | SHELL | TRANSCRIPTOME | ENGINEERING, BIOMEDICAL | PEARL OYSTER | PINCTADA-FUCATA | REFERENCE GENOME | PROTEINS | EXPRESSION | RNA-SEQ DATA | Multigene Family | Synteny - genetics | RNA, Messenger - genetics | Genome - genetics | Transcriptome - genetics | Phylogeny | RNA, Messenger - metabolism | Bivalvia - enzymology | Animal Shells - enzymology | Gene Expression Regulation, Enzymologic | Pinctada - genetics | Animals | Pinctada - enzymology | Bivalvia - genetics | Monophenol Monooxygenase - genetics | Evolution, Molecular | Genetic Linkage | Enzymes | Genes | Shells | Oysters | Gene expression | Maxima
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3. Full Text Proteomic profiling of cytosolic glutathione transferases from three bivalve species: Corbicula fluminea, Mytilus galloprovincialis and Anodonta cygnea
by Martins, José Carlos and Campos, Alexandre and Osório, Hugo and da Fonseca, Rute and Vasconcelos, Vítor
International Journal of Molecular Sciences, ISSN 1661-6596, 01/2014, Volume 15, Issue 2, pp. 1887 - 1900
Suspension-feeding bivalves are considered efficient toxin vectors with a relative insensitivity to toxicants compared to other aquatic organisms. This fact... 
Corbicula fluminea | Mytilus galloprovincialis | Detoxification | Glutathione transferases | Proteomics | Anodonta cygnea | S-TRANSFERASE | PROTEIN | proteomics | EDULIS | glutathione transferases | CYLINDROSPERMOPSIN | CHEMISTRY, MULTIDISCIPLINARY | POLLUTION | CLONING | PURIFICATION | CLAM RUDITAPES-DECUSSATUS | BLUE MUSSEL | detoxification | EXPRESSION | Animals | Corbicula - enzymology | Isoenzymes | Glutathione Transferase - metabolism | Cytosol - metabolism | Proteome | Enzyme Activation | Kinetics | Mytilus - enzymology | Anodonta - enzymology | Bivalvia - enzymology | Organisms | Aquatic ecosystems | Index Medicus
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4. Full Text Pitfalls in invertebrate proteasome assays
by Götze, Sandra and Bose, Aneesh and Abele, Doris and Sokolova, Inna M and Saborowski, Reinhard
Journal of Experimental Biology, ISSN 0022-0949, 04/2013, Volume 216, Issue 8, pp. 1351 - 1354
The ubiquitin-proteasome system controls a variety of essential intracellular processes through directed protein turnover. The invertebrate proteasome has... 
Crustacea | Epoxomicin | Bivalve | Proteasome | Protein catabolism | proteasome | epoxomicin | TISSUE | LONGEVITY | CADMIUM | bivalve | BIOLOGY | CRASSOSTREA-VIRGINICA | INHIBITORS | protein catabolism | LOBSTER | STRESS | Animals | Muscles - enzymology | Chymotrypsin - metabolism | Hemocytes - enzymology | Proteolysis | Crustacea - enzymology | Proteasome Inhibitors - metabolism | Enzyme Assays | Oligopeptides - metabolism | Proteasome Endopeptidase Complex - metabolism | Bivalvia - enzymology | Physiological aspects | Research | Ubiquitin-proteasome system | Bivalvia
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5. Full Text Exploring alternative biomarkers of pesticide pollution in clams
by Solé, Montserrat and Bonsignore, Martina and Rivera-Ingraham, Georgina and Freitas, Rosa
Marine Pollution Bulletin, ISSN 0025-326X, 11/2018, Volume 136, pp. 61 - 67
Acetylcholinesterase (AChE) is a reliable biomarker of pesticide exposure although in clams this activity is often very low or undetectable. Carboxylesterases... 
Organophosphorus pesticides | Chlorpyrifos oxon | Antioxidant enzymes | Carboxylesterases | Ruditapes decussatus | CARBOXYLESTERASE ACTIVITY | ACETYLCHOLINESTERASE ACTIVITY | SALINITY CHANGES | MYTILUS-GALLOPROVINCIALIS | ESTERASE-ACTIVITIES | OXIDATIVE STRESS BIOMARKERS | ENVIRONMENTAL SCIENCES | IN-VITRO | MARINE & FRESHWATER BIOLOGY | CHOLINESTERASE ACTIVITIES | RUDITAPES-PHILIPPINARUM | EXPOSURE | Gills - enzymology | Antioxidants - metabolism | Carboxylesterase - analysis | Environmental Monitoring - methods | Environmental Biomarkers | Gills - chemistry | Pesticides - analysis | Water Pollutants, Chemical - analysis | Bivalvia - enzymology | Spain | Animals | Digestive System - chemistry | Digestive System - enzymology | Bivalvia - chemistry | Antioxidants | Pollution | Enzyme inhibitors | Metabolites | Isoenzymes | Glutathione transferase | Marine sciences | Pesticides | Environmental aspects | Physiological aspects | Esters | Peroxidase
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6. Full Text Gene cloning and catalytic characterization of cold-adapted lipase of Photobacterium sp. MA1-3 isolated from blood clam
by Kim, Young Ok and Kim, Hyung Kwoun and Khosasih, Vivia and Nam, Bo-Hye and Lee, Sang-Jun and Suwanto, Antonius
Journal of Bioscience and Bioengineering, ISSN 1389-1723, 12/2012, Volume 114, Issue 6, pp. 589 - 595
A lipase-producing strain (MA1-3) was isolated from the intestine of a blood clam caught at Namhae, Korea. The lipase gene was cloned by shotgun cloning and... 
Cold-adapted enzyme | Transesterification | Lipase | Biodiesel | Photobacterium | BIOTECHNOLOGY | BIOCATALYSTS | ACID | FOOD SCIENCE & TECHNOLOGY | LIPOLYTICUM | ACTIVE ESTERASE | PSYCHROTROPH | IMPACT | OIL | BIODIESEL PRODUCTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | Solvents | Cold Temperature | Biocatalysis | Molecular Weight | Photobacterium - isolation & purification | Enzyme Stability | Substrate Specificity | Lipase - metabolism | Olive Oil | Lipase - chemistry | Soybean Oil - metabolism | Alcohols - metabolism | Esterification | Methanol - metabolism | Animals | Cloning, Molecular | Photobacterium - enzymology | Plant Oils - metabolism | Photobacterium - genetics | Bivalvia - microbiology | Biofuels - supply & distribution | Lipase - genetics | Genetic aspects | Cloning | Genes | Biodiesel fuels
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7. Full Text Neuroenzymatic activity and physiological energetics in Manila clam, Ruditapes philippinarum, during short-term sublethal exposure to harmful alga, Heterocapsa circularisquama
by Basti, Leila and Nagai, Satoshi and Watanabe, Satoshi and Oda, Tatsuya and Tanaka, Yuji
Aquatic Toxicology, ISSN 0166-445X, 07/2016, Volume 176, pp. 76 - 87
The harmful alga, , causes recurrent mortalities of bivalve molluscs in Japan, with demonstrated hemolysis and cytotoxicity in rabbit erythrocytes, HeLa cells,... 
Harmful algal blooms | Scope for growth | Bivalves | Acetylcholinesterase | Heterocapsa circularisquama | MUSSEL MYTILUS-EDULIS | DINOFLAGELLATE ALEXANDRIUM-TAMARENSE | BODY-SIZE | PINCTADA-FUCATA-MARTENSII | PEARL OYSTER | PARTICLE SELECTION | SYDNEY ROCK OYSTERS | FOOD CONCENTRATION | LATERAL CILIARY ACTIVITY | MARINE & FRESHWATER BIOLOGY | TOXICOLOGY | TOXIC DINOFLAGELLATE | Rabbits | Harmful Algal Bloom | Bivalvia - growth & development | Humans | Gills - metabolism | Mytilus - drug effects | Bivalvia - enzymology | Erythrocytes - drug effects | Mytilus - growth & development | Water Pollutants, Chemical - metabolism | Gills - drug effects | Animals | Water Pollutants, Chemical - toxicity | Dinoflagellida - metabolism | Erythrocytes - cytology | Erythrocytes - enzymology | HeLa Cells | Mytilus - enzymology | Bivalvia - drug effects | Acetylcholinesterase - metabolism | Energy Metabolism - drug effects | Marine biology | Aquaculture industry | Research institutes | Index Medicus
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8. Full Text Environmentally realistic concentrations of the antibiotic Trimethoprim affect haemocyte parameters but not antioxidant enzyme activities in the clam Ruditapes philippinarum
by Matozzo, Valerio and De Notaris, Chiara and Finos, Livio and Filippini, Raffaella and Piovan, Anna
Environmental Pollution, ISSN 0269-7491, 11/2015, Volume 206, pp. 567 - 574
Several biomarkers were measured to evaluate the effects of Trimethoprim (TMP; 300, 600 and 900 ng/L) in the clam after exposure for 1, 3 and 7 days. The... 
Trimethoprim | Antibiotic | Haemocyte | Antioxidant enzyme | Clam | RIVER DISCHARGE | NONSTEROIDAL ANTIINFLAMMATORY DRUG | ELLIPTIO-COMPLANATA | WASTE-WATER CONTAMINANTS | AQUATIC ENVIRONMENT | DREISSENA-POLYMORPHA | IBUPROFEN | ENVIRONMENTAL SCIENCES | CHINA IMPACTS | MUSSEL MYTILUS-GALLOPROVINCIALIS | IMMUNE PARAMETERS | Hemocytes - enzymology | Hemolymph - drug effects | Antioxidants - metabolism | Cell Count | Water Pollutants, Chemical - analysis | Bivalvia - enzymology | Dose-Response Relationship, Drug | Animals | Hemolymph - enzymology | Water Pollutants, Chemical - toxicity | Hemocytes - drug effects | Trimethoprim - toxicity | Cell Proliferation - drug effects | Seasons | Bivalvia - drug effects | Trimethoprim - analysis | Hemocytes - cytology | Antioxidants | Antibacterial agents | Analysis | Lysozyme | Tanks | Biomarkers | Mathematical models | Exposure | Assessments | Counting
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9. Full Text Assessment of environmental pollution at Balearic Islands applying oxidative stress biomarkers in the mussel Mytilus galloprovincialis
by Box, A and Sureda, A and Galgani, F and Pons, A and Deudero, S
Comparative Biochemistry and Physiology, Part C, ISSN 1532-0456, 2007, Volume 146, Issue 4, pp. 531 - 539
The antioxidant enzyme response of the mussel to different degree of pollution was investigated. Antioxidant enzyme activities – catalase (CAT), glutathione... 
Pollution | Western Mediterranean | Mussels | Antioxidant enzymes | Biomarkers | Lipid peroxidation | Balearic Islands | Mytilus galloprovincialis | AQUATIC ORGANISMS | ANTIOXIDANT RESPONSES | FIELD TRANSLOCATION EXPERIMENT | biomarkers | TRANSPLANTED MUSSELS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LAGOON-OF-VENICE | antioxidant enzymes | pollution | BIOLOGICAL IMPACT | lipid peroxidation | ZOOLOGY | LABORATORY CONDITIONS | ENDOCRINOLOGY & METABOLISM | Mytilus gallaprovincialis | TOXICOLOGY | GLUTATHIONE-S-TRANSFERASE | mussels | SUPEROXIDE-DISMUTASE | PERNA-VIRIDIS | Adaptation, Physiological | Biomarkers - metabolism | Geography | Gills - enzymology | Tissue Extracts - chemistry | Exocrine Glands - enzymology | Oxidoreductases - metabolism | Exocrine Glands - drug effects | Environmental Monitoring - methods | Spain | Gills - drug effects | Animals | Digestive System - drug effects | Digestive System - enzymology | Bivalvia - metabolism | Environmental Pollutants - toxicity | Oxidative Stress - drug effects | Bivalvia - drug effects | Mediterranean Sea | Environmental Pollution - analysis | Antioxidants | Radicals (Chemistry) | Analysis | Environmental aspects | Peroxidase | Biological markers
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10. Full Text Multibiomarker biomonitoring approach using three bivalve species in the Ebro Delta (Catalonia, Spain)
by Dallarés, Sara and Carrasco, Noelia and Álvarez-Muñoz, Diana and Rambla-Alegre, Maria and Solé, Montserrat
Environmental Science and Pollution Research, ISSN 0944-1344, 12/2018, Volume 25, Issue 36, pp. 36745 - 36758
Bivalves have proved to be useful bioindicators for environmental pollution. In the present study, mussels (Mytilus galloprovincialis), cockles (Cerastoderma... 
Cockle | Mussel | Contaminants | Razor shell | Pesticides | Biomarkers | Histology | Phycotoxins | CRASSOSTREA-GIGAS | MYTILUS-GALLOPROVINCIALIS | COASTAL AREAS | CARBOXYLESTERASES | OXIDATIVE STRESS RESPONSES | ENVIRONMENTAL SCIENCES | LIQUID-CHROMATOGRAPHY | RIVER DELTA | PESTICIDE POLLUTION | Biomarkers - metabolism | Cardiidae - drug effects | Environmental Monitoring - methods | Estuaries | Mytilus - drug effects | Pesticides - analysis | Water Pollutants, Chemical - analysis | Cardiidae - enzymology | Bivalvia - enzymology | Spain | Animals | Lipid Peroxidation - drug effects | Mytilus - enzymology | Bivalvia - drug effects | Antioxidants | Razors | Enzymes | Pollution | Indicators (Biology) | Biological monitoring | Biomonitoring | Marine pollution | Lipid peroxidation | Lipids | Mollusks | Biochemistry | Pesticide pollution | Carboxylesterase | Neurotoxicity | Bioaccumulation | Pollution effects | Bioindicators | Pollutants | Peroxidation | Shells | Indicator species | Environmental effects | Mussels | Cockles | Biochemical markers
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11. Full Text Multiple I-type lysozymes in the hydrothermal vent mussel bathymodiolus azoricus and their role in symbiotic plasticity
by Detree, Camille and Chabenat, Apolline and Lallier, François H and Satoh, Nori and Shoguchi, Eiichi and Tanguy, Arnaud and Mary, Jean
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148988
The aim of this study was first to identify lysozymes paralogs in the deep sea mussel Bathymodiolus azoricus then to measure their relative expression or... 
EASTERN OYSTER | DE-NOVO | MID-ATLANTIC RIDGE | INVERTEBRATE-TYPE LYSOZYMES | GOOSE-TYPE LYSOZYME | RECOMBINANT PROTEIN | MULTIDISCIPLINARY SCIENCES | CDNA CLONING | ANTIMICROBIAL ACTIVITY | ADAPTIVE EVOLUTION | OYSTER CRASSOSTREA-VIRGINICA | Gills - microbiology | Molecular Sequence Data | Muramidase - biosynthesis | Phylogeny | Symbiosis - genetics | Methylococcaceae - physiology | Chlorobi - classification | Isoenzymes - metabolism | Ecosystem | Bivalvia - microbiology | Gills - physiology | Gram-Negative Bacteria - genetics | Gram-Negative Bacteria - physiology | Amino Acid Sequence | Chlorobi - enzymology | Hydrothermal Vents | Isoenzymes - genetics | Methylococcaceae - classification | Muramidase - genetics | Bacterial Proteins - genetics | Bivalvia - physiology | Muramidase - metabolism | Chlorobi - physiology | Gram-Negative Bacteria - enzymology | Sequence Alignment | Animals | Methylococcaceae - genetics | Methylococcaceae - enzymology | Bacterial Proteins - metabolism | Bacterial Proteins - biosynthesis | Gene Expression Regulation, Bacterial | Isoenzymes - biosynthesis | Chlorobi - genetics | Gram-Negative Bacteria - classification | Hydrothermal vent ecology | Analysis | Lysozyme | Mid-ocean ridges | Microbial activity | Deep sea | Genomics | Mollusks | Antiinfectives and antibacterials | Experiments | Deep sea environments | Symbionts | Sulfides | Microorganisms | Population | Bacteria | Oxidation | Research ships | Adaptation | Symbiosis | Methanotrophic bacteria | Cloning | Antimicrobial agents | Gene expression | Biological activity | Mussels | MOX | Evolution & development | Sciences of the Universe | Ocean, Atmosphere
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12. Full Text Transcriptional responses of glutathione transferase genes in Ruditapes philippinarum exposed to microcystin-LR
by Reis, Bruno and Carneiro, Mariana and Machado, João and Azevedo, Joana and Vasconcelos, Vitor and Martins, José Carlos
International Journal of Molecular Sciences, ISSN 1661-6596, 04/2015, Volume 16, Issue 4, pp. 8397 - 8414
Glutathione Transferases (GSTs) are phase II detoxification enzymes known to be involved in the molecular response against microcystins (MCs) induced toxicity.... 
Biomarker | Real-time PCR | R. philippinarum | Detoxification | Glutathione transferases | Microcystins | PROTEIN PHOSPHATASE-1 | AQUATIC ORGANISMS | philippinarum | S-TRANSFERASE | OXIDATIVE STRESS | glutathione transferases | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITORY-ACTIVITY | MYTILUS-GALLOPROVINCIALIS | real-time PCR | biomarker | CHEMISTRY, MULTIDISCIPLINARY | CYANOBACTERIAL TOXINS | microcystins | CARP CYPRINUS-CARPIO | MANILA CLAM | detoxification | AERUGINOSA CELLS | Microcystins - pharmacology | Gills - enzymology | Animals | Glutathione Transferase - genetics | Enzyme Induction | Transcription, Genetic | Bivalvia - genetics | Gills - immunology | Bivalvia - enzymology | Hepatopancreas - enzymology | Bivalvia - immunology | Hepatopancreas - immunology | Enzymes | Mollusks | Gene expression | Toxicity
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13. Full Text The Effects of Copper on Na+/K+-ATPase and Aquaporin Expression in Two Euryhaline Invertebrates
by Boyle, R T and Boyle, R T and Oliveira, L F and Oliveira, L F and Bianchini, A and Bianchini, A and Souza, M M and Souza, M M
Bulletin of Environmental Contamination and Toxicology, ISSN 0007-4861, 3/2013, Volume 90, Issue 3, pp. 387 - 390
We used immunocytochemical and fluorometric techniques to show that gill cells of two marine invertebrates, the crab Neohelice granulata (osmoregulator) and... 
Pollution, general | Environmental Health | Ecotoxicology | Immunocytochemistry | Gills | Metal | Crab | Clam | Environment | Protein expression | Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution | Environmental Chemistry | Soil Science & Conservation | GILL | ISOLATED MANTLE CELLS | CLAM MESODESMA-MACTROIDES | MECHANISMS | TOXICITY | FRESH-WATER | ENVIRONMENTAL SCIENCES | TOX