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Nature Immunology, ISSN 1529-2908, 10/2015, Volume 16, Issue 11, pp. 1142 - 1152
Mitochondria need to be juxtaposed to phagosomes for the synergistic production of ample reactive oxygen species (ROS) in phagocytes to kill pathogens.... 
ACTIVATION | RECOGNITION | SIGNALING PATHWAY | RAC GTPASE | PHOSPHORYLATION | PROTEIN-KINASE | TOLL-LIKE RECEPTORS | HIPPO PATHWAY | IMMUNOLOGY | T-CELLS | IMMUNODEFICIENCY | Phagosomes - microbiology | Protein-Serine-Threonine Kinases - deficiency | Sepsis - etiology | Reactive Oxygen Species - metabolism | Protein Kinase C-alpha - metabolism | Minor Histocompatibility Antigens | Bacterial Infections - etiology | Humans | rac GTP-Binding Proteins - metabolism | Mitochondria - immunology | Phagosomes - immunology | Ubiquitination | Bacterial Infections - immunology | Sepsis - metabolism | rac GTP-Binding Proteins - genetics | Toll-Like Receptors - metabolism | rho Guanine Nucleotide Dissociation Inhibitor beta - metabolism | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Sepsis - immunology | Signal Transduction | Mice, Inbred C57BL | Phagosomes - metabolism | Protein-Serine-Threonine Kinases - genetics | Blood Bactericidal Activity - immunology | Mitochondria - metabolism | Phagocytes - metabolism | Phagocytes - immunology | Mitochondria - microbiology | Mice, Knockout | TNF Receptor-Associated Factor 6 | Animals | Phagocytes - microbiology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Bacterial Infections - metabolism | Physiological aspects | Phagocytes | Reactive oxygen species | Genetic aspects | Research
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0172163
Serum Bactericidal Activity (SBA) assay is the method of choice to evaluate the complement- mediated functional activity of both infection-and vaccine-induced... 
COMPLEMENT | STANDARDIZATION | INFLUENZAE TYPE-B | ASSAY | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | NEISSERIA-MENINGITIDIS | ANTIBODY | SALMONELLA | HAEMOPHILUS-INFLUENZAE | SEROGROUP | Immune Sera - immunology | Bacteria - metabolism | Neisseria meningitidis - metabolism | Reproducibility of Results | Species Specificity | Immune Sera - blood | Shigella flexneri - metabolism | Citrobacter freundii - metabolism | Shigella sonnei - metabolism | Adenosine Triphosphate - immunology | Blood Bactericidal Activity - immunology | Linear Models | Citrobacter freundii - immunology | Salmonella enterica - metabolism | Microbial Viability - immunology | Neisseria meningitidis - immunology | Bacteria - immunology | Animals | Shigella flexneri - immunology | Adenosine Triphosphate - metabolism | Salmonella enterica - immunology | Mice | Shigella sonnei - immunology | High-Throughput Screening Assays - methods | Measurement | Usage | Analysis | Bacteria | Serum | Research | High-throughput screening (Biochemical assaying) | Adenosine triphosphate | Salmonella | Laboratories | Serum bactericidal activity | Luminescence | Antibodies | Complement | Vaccines | Assaying | Microorganisms | Citrobacter | Antigens | Immunoglobulins | Automation | Data acquisition | Colonies | Agar | Glycerol | Data processing | Metabolism | Survival | Bactericidal activity | Dilution | ATP | Methods
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2011, Volume 186, Issue 6, pp. 3622 - 3631
The damage-associated molecular-pattern S100A9 is found at inflammatory sites in infections and various autoimmune diseases. It is released at very high... 
MIGRATION | RECEPTOR-MEDIATED PHAGOCYTOSIS | ADHESION | IN-VITRO | ACTIVATION | REACTIVE OXYGEN | TYROSINE PHOSPHORYLATION | FC-GAMMA-R | HUMAN MACROPHAGES | IMMUNOLOGY | PROTEINS S100A8 | Reactive Oxygen Species - metabolism | Neutrophils - enzymology | Protein-Tyrosine Kinases - metabolism | Humans | Receptors, Pattern Recognition - physiology | Neutrophils - immunology | Phagocytosis - immunology | Escherichia coli - immunology | Blood Bactericidal Activity - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Enzyme Activation - immunology | Host-Pathogen Interactions - immunology | Calgranulin B - physiology | Mitogen-Activated Protein Kinase 3 - metabolism | Escherichia coli - metabolism | Neutrophils - microbiology | Proto-Oncogene Proteins c-akt - metabolism | Syk Kinase | Mitogen-Activated Protein Kinase 1 - metabolism | Calgranulin B | Reactive Oxygen Species | Escherichia coli | Neutrophils | Intracellular Signaling Peptides and Proteins | Blood Bactericidal Activity | Phosphatidylinositol 3-Kinases | Proto-Oncogene Proteins c-akt | Host-Pathogen Interactions | Life Sciences | Receptors, Pattern Recognition | Toxicology | Enzyme Activation | Protein-Tyrosine Kinases | Mitogen-Activated Protein Kinase 1 | Phagocytosis | Mitogen-Activated Protein Kinase 3
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2006, Volume 177, Issue 1, pp. 501 - 510
Neisseria meningitidis binds factor H (M), a key regulator of the alternative complement pathway. A similar to 29 kD fH-binding protein expressed in the... 
MOLECULAR-MECHANISM | OUTER-MEMBRANE PROTEINS | GENETIC-ANALYSIS | AMPLIFICATION CONVERTASE | SEROGROUP-B | DEFICIENCY STATES | SIALIC-ACID | IMMUNOLOGY | BACTERICIDAL ANTIBODIES | MONOCLONAL-ANTIBODIES | B NEISSERIA-MENINGITIDIS | Complement Factor H - antagonists & inhibitors | Vaccines, DNA - genetics | Neisseria meningitidis - metabolism | Humans | Antigens, Bacterial - immunology | Porins - metabolism | Vaccines, DNA - immunology | Molecular Sequence Data | Antigens, Bacterial - genetics | Blood Bactericidal Activity - genetics | Genetic Variation | Neisseria meningitidis - immunology | Gene Deletion | Adjuvants, Immunologic - metabolism | Adjuvants, Immunologic - genetics | Adult | Neisseria meningitidis - genetics | Bacterial Proteins - immunology | Complement Pathway, Alternative - genetics | Binding, Competitive - immunology | Amino Acid Sequence | Complement Factor H - immunology | Meningococcal Vaccines - genetics | Bacterial Adhesion - immunology | Meningococcal Vaccines - metabolism | Bacterial Proteins - genetics | Blood Bactericidal Activity - immunology | Complement Factor H - metabolism | Bacterial Outer Membrane Proteins - metabolism | Complement Pathway, Alternative - immunology | Bacterial Proteins - metabolism | Ligands | Antibodies, Monoclonal - metabolism | Meningococcal Vaccines - immunology | Binding Sites, Antibody | Vaccines, DNA - metabolism | Antigens, Bacterial - metabolism
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2010, Volume 185, Issue 1, pp. 468 - 476
Journal Article
Vaccine, ISSN 0264-410X, 2010, Volume 29, Issue 5, pp. 1072 - 1081
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2006, Volume 177, Issue 1, pp. 519 - 526
Journal Article
Journal Article