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by Saxena, Richa and Hivert, Marie-France and Langenberg, Claudia and Tanaka, Toshiko and Pankow, James S and Vollenweider, Peter and Lyssenko, Valeriya and Bouatia-Naji, Nabila and Dupuis, Josée and Jackson, Anne U and Kao, W H Linda and Li, Man and Glazer, Nicole L and Manning, Alisa K and Luan, Jian'an and Stringham, Heather M and Prokopenko, Inga and Johnson, Toby and Grarup, Niels and Boesgaard, Trine W and Lecoeur, Cécile and Shrader, Peter and O'Connell, Jeffrey and Ingelsson, Erik and Couper, David J and Rice, Kenneth and Song, Kijoung and Andreasen, Camilla H and Dina, Christian and Köttgen, Anna and Le Bacquer, Olivier and Pattou, François and Taneera, Jalal and Steinthorsdottir, Valgerdur and Rybin, Denis and Ardlie, Kristin and Sampson, Michael and Qi, Lu and van Hoek, Mandy and Weedon, Michael N and Aulchenko, Yurii S and Voight, Benjamin F and Grallert, Harald and Balkau, Beverley and Bergman, Richard N and Bielinski, Suzette J and Bonnefond, Amelie and Bonnycastle, Lori L and Borch-Johnsen, Knut and Böttcher, Yvonne and Brunner, Eric and Buchanan, Thomas A and Bumpstead, Suzannah J and Cavalcanti-Proença, Christine and Charpentier, Guillaume and Chen, Yii-Der Ida and Chines, Peter S and Collins, Francis S and Cornelis, Marilyn and J Crawford, Gabriel and Delplanque, Jerome and Doney, Alex and Egan, Josephine M and Erdos, Michael R and Firmann, Mathieu and Forouhi, Nita G and Fox, Caroline S and Goodarzi, Mark O and Graessler, Jürgen and Hingorani, Aroon and Isomaa, Bo and Jørgensen, Torben and Kivimaki, Mika and Kovacs, Peter and Krohn, Knut and Kumari, Meena and Lauritzen, Torsten and Lévy-Marchal, Claire and Mayor, Vladimir and McAteer, Jarred B and Meyre, David and Mitchell, Braxton D and Mohlke, Karen L and Morken, Mario A and Narisu, Narisu and Palmer, Colin N A and Pakyz, Ruth and Pascoe, Laura and Payne, Felicity and Pearson, Daniel and Rathmann, Wolfgang and Sandbaek, Annelli and Sayer, Avan Aihie and Scott, Laura J and Sharp, Stephen J and Sijbrands, Eric and Singleton, Andrew and Siscovick, David S and Smith, Nicholas L and Sparsø, Thomas and ... and GIANT consortium and the MAGIC investigators and GIANT Consortium and MAGIC Investigators and MAGIC investigators
Nature genetics, ISSN 1546-1718, 2010, Volume 42, Issue 2, pp. 142 - 148
Journal Article
by Dupuis, Josée and Langenberg, Claudia and Prokopenko, Inga and Saxena, Richa and Soranzo, Nicole and Jackson, Anne U and Wheeler, Eleanor and Glazer, Nicole L and Bouatia-Naji, Nabila and Gloyn, Anna L and Lindgren, Cecilia M and Mägi, Reedik and Morris, Andrew P and Randall, Joshua and Johnson, Toby and Elliott, Paul and Rybin, Denis and Thorleifsson, Gudmar and Steinthorsdottir, Valgerdur and Henneman, Peter and Grallert, Harald and Dehghan, Abbas and Hottenga, Jouke Jan and Franklin, Christopher S and Navarro, Pau and Song, Kijoung and Goel, Anuj and Perry, John R B and Egan, Josephine M and Lajunen, Taina and Grarup, Niels and Sparsø, Thomas and Doney, Alex and Voight, Benjamin F and Stringham, Heather M and Li, Man and Kanoni, Stavroula and Shrader, Peter and Cavalcanti-Proença, Christine and Kumari, Meena and Qi, Lu and Timpson, Nicholas J and Gieger, Christian and Zabena, Carina and Rocheleau, Ghislain and Ingelsson, Erik and An, Ping and O'Connell, Jeffrey and Luan, Jian'an and Elliott, Amanda and McCarroll, Steven A and Payne, Felicity and Roccasecca, Rosa Maria and Pattou, François and Sethupathy, Praveen and Ardlie, Kristin and Ariyurek, Yavuz and Balkau, Beverley and Barter, Philip and Beilby, John P and Ben-Shlomo, Yoav and Benediktsson, Rafn and Bennett, Amanda J and Bergmann, Sven and Bochud, Murielle and Boerwinkle, Eric and Bonnefond, Amélie and Bonnycastle, Lori L and Borch-Johnsen, Knut and Böttcher, Yvonne and Brunner, Eric and Bumpstead, Suzannah J and Charpentier, Guillaume and Chen, Yii-Der Ida and Chines, Peter and Clarke, Robert and Coin, Lachlan J M and Cooper, Matthew N and Cornelis, Marilyn and Crawford, Gabe and Crisponi, Laura and Day, Ian N M and de Geus, Eco J C and Delplanque, Jerome and Dina, Christian and Erdos, Michael R and Fedson, Annette C and Fischer-Rosinsky, Antje and Forouhi, Nita G and Fox, Caroline S and Frants, Rune and Franzosi, Maria Grazia and Galan, Pilar and Goodarzi, Mark O and Graessler, Jürgen and Groves, Christopher J and Grundy, Scott and Gwilliam, Rhian and Gyllensten, Ulf and Hadjadj, Samy and ... and DIAGRAM Consortium and Anders Hamsten on behalf of Procardis Consortium and Global BPgen Consortium and GIANT Consortium and the MAGIC investigators and Anders Hamsten Procardis Consortiu and MAGIC Investigators and MAGIC investigators
Nature genetics, ISSN 1546-1718, 01/2010, Volume 42, Issue 2, pp. 105 - 116
Journal Article
Nature (London), ISSN 1476-4687, 04/2012, Volume 484, Issue 7394, pp. 333 - 338
.... Impaired insulin action in peripheral tissues is a major pathogenic factor. Insulin stimulates glucose uptake in adipose tissue through the GLUT4... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Transcription Factors - chemistry | Diabetes Mellitus - genetics | Humans | Male | RNA, Messenger - metabolism | Adipose Tissue - metabolism | Protein Isoforms - chemistry | Nuclear Proteins - deficiency | Lipogenesis | Body Mass Index | Glucose Transporter Type 4 - genetics | Adipose Tissue - pathology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry | Genotype | Glucose - pharmacology | Nuclear Proteins - chemistry | Mice, Knockout | Insulin - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Insulin Resistance - genetics | Glucose - metabolism | Mice | Blood Glucose - metabolism | Homeostasis - genetics | Cohort Studies | Diabetes Mellitus - blood | Body Weight | Glucose Transporter Type 4 - metabolism | Transcription Factors - deficiency | Adipose Tissue - cytology | Molecular Sequence Data | Obesity - genetics | Promoter Regions, Genetic - genetics | Protein Isoforms - metabolism | Adiposity | Female | Nuclear Proteins - genetics | Insulin - pharmacology | Glucose Intolerance - genetics | Cross-Sectional Studies | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Cells, Cultured | Diabetes Mellitus - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | Obesity - metabolism | Transcription Factors - metabolism | Animals | Glucose Transporter Type 4 - biosynthesis | Adipocytes - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Protein Isoforms - genetics
Journal Article
by Prokopenko, Inga and Langenberg, Claudia and Florez, Jose C and Saxena, Richa and Soranzo, Nicole and Thorleifsson, Gudmar and Loos, Ruth J F and Manning, Alisa K and Jackson, Anne U and Aulchenko, Yurii and Potter, Simon C and Erdos, Michael R and Sanna, Serena and Hottenga, Jouke-Jan and Wheeler, Eleanor and Kaakinen, Marika and Lyssenko, Valeriya and Chen, Wei-Min and Ahmadi, Kourosh and Beckmann, Jacques S and Bergman, Richard N and Bochud, Murielle and Bonnycastle, Lori L and Buchanan, Thomas A and Cao, Antonio and Cervino, Alessandra and Coin, Lachlan and Collins, Francis S and Crisponi, Laura and de Geus, Eco J C and Dehghan, Abbas and Deloukas, Panos and Doney, Alex S F and Elliott, Paul and Freimer, Nelson and Gateva, Vesela and Herder, Christian and Hofman, Albert and Hughes, Thomas E and Hunt, Sarah and Illig, Thomas and Inouye, Michael and Isomaa, Bo and Johnson, Toby and Kong, Augustine and Krestyaninova, Maria and Kuusisto, Johanna and Laakso, Markku and Lim, Noha and Lindblad, Ulf and Lindgren, Cecilia M and McCann, Owen T and Mohlke, Karen L and Morris, Andrew D and Naitza, Silvia and Orrù, Marco and Palmer, Colin N A and Pouta, Anneli and Randall, Joshua and Rathmann, Wolfgang and Saramies, Jouko and Scheet, Paul and Scott, Laura J and Scuteri, Angelo and Sharp, Stephen and Sijbrands, Eric and Smit, Jan H and Song, Kijoung and Steinthorsdottir, Valgerdur and Stringham, Heather M and Tuomi, Tiinamaija and Tuomilehto, Jaakko and Uitterlinden, André G and Voight, Benjamin F and Waterworth, Dawn and Wichmann, H-Erich and Willemsen, Gonneke and Witteman, Jacqueline C M and Yuan, Xin and Zhao, Jing Hua and Zeggini, Eleftheria and Schlessinger, David and Sandhu, Manjinder and Boomsma, Dorret I and Uda, Manuela and Spector, Tim D and Penninx, Brenda WJH and Altshuler, David and Vollenweider, Peter and Jarvelin, Marjo Riitta and Lakatta, Edward and Waeber, Gerard and Fox, Caroline S and Peltonen, Leena and Groop, Leif C and Mooser, Vincent and Cupples, L Adrienne and Thorsteinsdottir, Unnur and Boehnke, Michael and Barroso, Inês and ... and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Medicine, School of Public Health and Community Medicine and Sahlgrenska Academy
Nature genetics, ISSN 1546-1718, 2008, Volume 41, Issue 1, pp. 77 - 81
Journal Article
PLoS medicine, ISSN 1549-1676, 05/2007, Volume 4, Issue 5, pp. e158 - 0879
.... Impaired glucose uptake in skeletal muscle is believed to be one of the earliest features in the natural history of T2DM, although underlying mechanisms remain obscure... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Diabetes Mellitus, Type 2 - genetics | Humans | Qb-SNARE Proteins - genetics | Adipocytes - cytology | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Polymerase Chain Reaction | Carrier Proteins - physiology | Insulin - pharmacology | Genetic Predisposition to Disease | Glucose Intolerance - genetics | Cells, Cultured | Gene Expression Regulation - physiology | DNA-Binding Proteins - genetics | Hypoglycemic Agents - pharmacology | Linkage Disequilibrium | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Promoter Regions, Genetic - physiology | Homeostasis - physiology | Protein Array Analysis | Blood Glucose - genetics | Polymorphism, Single Nucleotide | Glucose Clamp Technique | Muscle, Skeletal - pathology | Blood Glucose - metabolism | Proto-Oncogene Proteins c-bcl-6 | Proteins | Glucose metabolism | Medical research | Medicine, Experimental | Gene expression | Observations | Health aspects | Nutrition and Metabolism | Genetics and Genomics | Genetics | Physiology | Diabetes | Diabetes and Endocrinology | Endocrinology | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article