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Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0175486
We optically measured effects of orally available ivacaftor (Kalydeco (R)) on sweat rates of identified glands in 3 R117H subjects, each having a unique set of... 
TRANSMEMBRANE CONDUCTANCE REGULATOR | GLANDS | GENE | MESSENGER-RNA TRANSCRIPTS | PARTIAL PENETRANCE | MULTIDISCIPLINARY SCIENCES | CODING SEQUENCES | MUTATION | DISEASE | CYSTIC-FIBROSIS | CFTR POTENTIATOR | Muscarinic Agonists - pharmacology | Sweat - secretion | Humans | Male | Quinolones - pharmacology | Aminophenols - pharmacology | Methacholine Chloride - administration & dosage | Gene Deletion | Methacholine Chloride - pharmacology | Adrenergic beta-Agonists - administration & dosage | Adult | Female | Injections, Intradermal | Muscarinic Agonists - administration & dosage | Administration, Oral | Chloride Channel Agonists - pharmacology | Adrenergic beta-Agonists - pharmacology | Sweating - genetics | Exons - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Sweating - drug effects | Quinolones - administration & dosage | Ion Channel Gating - genetics | Analysis of Variance | Chloride Channel Agonists - administration & dosage | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mutation | Aminophenols - administration & dosage | Ion Channel Gating - drug effects | Ivacaftor | Care and treatment | Gene mutations | Methacholine | Cystic fibrosis | Dosage and administration | Research | Wine | Pediatrics | Acetylcholine receptors (muscarinic) | Laboratories | Linkage disequilibrium | Glands | Biology | Iontophoresis | Membrane conductance | Chloride | Intestine | Anion channels | Genetics | Physiology | Children | Sweat | Digestive tract | Gating | Channel opening | Secretion | Channel gating | Bioassays | Organs | Chloride transport | Ion transport | Medical screening | Medicine | Clear cells | Lungs | Alleles | In vivo methods and tests | Conductance | Cystic fibrosis transmembrane conductance regulator | Molecular biology
Journal Article