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The American Journal of Human Genetics, ISSN 0002-9297, 04/2012, Volume 90, Issue 4, pp. 661 - 674
Bone morphogenetic protein 1 (BMP1) is an astacin metalloprotease with important cellular functions and diverse substrates, including extracellular-matrix... 
PROCOLLAGEN C-PROTEINASE | AXIAL SKELETON | IMPERFECTA | RETINOIC ACID | GENETICS & HEREDITY | MUTATIONS | MORPHOGENETIC PROTEIN-1 | METALLOPROTEINASES | CLEAVAGE | IDENTIFICATION | EXPRESSION | Osteogenesis - physiology | Peptide Fragments | Humans | Child, Preschool | Molecular Sequence Data | Male | Genetic Loci | Exome | Bone Morphogenetic Protein 1 - genetics | Base Sequence | Bone and Bones - metabolism | Heat-Shock Proteins | Diphosphonates - therapeutic use | Female | Cell Differentiation | Collagen - biosynthesis | Bone Morphogenetic Protein 1 - metabolism | Osteogenesis - genetics | Osteoblasts - drug effects | Osteoblasts - physiology | Osteogenesis - drug effects | Bone Density Conservation Agents - therapeutic use | Bone Morphogenetic Protein 1 - physiology | Zebrafish - genetics | Animals | Bone Morphogenetic Protein 1 - secretion | Zebrafish - metabolism | Protein Processing, Post-Translational | Mutation | Fractures, Bone - drug therapy | Fractures, Bone - prevention & control | Osteoporosis | Gene mutations | Causes of | Bone morphogenetic proteins | Chemical properties | Research | Nucleotide sequencing | DNA sequencing | Post-translational modification | Peptides | Analysis | Collagen | Medical genetics | Bones | Transforming growth factors | Density | Cells | Proteins | Human subjects | Signal transduction | Zebrafish | Genetics | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 11/2018, Volume 9, Issue 1, pp. 4831 - 11
Much of the mammalian skeleton originates from a cartilage template eventually replaced by bone via endochondral ossification. Despite much knowledge about... 
CHONDROCYTE HYPERTROPHY | ENDOCHONDRAL BONE-GROWTH | MULTIDISCIPLINARY SCIENCES | AEROBIC GLYCOLYSIS | OSTEOBLASTS | INDIAN-HEDGEHOG | DIFFERENTIATION | SMAD | EXPRESSION | CHONDROGENESIS | CARTILAGE | Bone Morphogenetic Protein 1 - deficiency | Bone Morphogenetic Protein 2 - pharmacology | Chondrocytes - cytology | Chondrogenesis - genetics | Embryo, Mammalian | Male | Chondrocytes - drug effects | Bone Morphogenetic Protein 1 - genetics | Mechanistic Target of Rapamycin Complex 1 - genetics | Gene Expression Regulation, Developmental | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Bone Morphogenetic Protein 2 - metabolism | Bone Morphogenetic Protein Receptors, Type I - deficiency | Bone and Bones - metabolism | Cartilage - cytology | Female | Osteoblasts - cytology | Chondrocytes - metabolism | Osteogenesis - genetics | Bone and Bones - cytology | Animals, Newborn | Bone Morphogenetic Protein 2 - genetics | Cartilage - growth & development | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Osteoblasts - drug effects | Bone Morphogenetic Protein Receptors, Type I - genetics | Signal Transduction - genetics | Cartilage - metabolism | Mechanistic Target of Rapamycin Complex 1 - metabolism | Mice, Knockout | Animals | Glucose Transporter Type 1 - deficiency | Glucose Transporter Type 1 - genetics | Cell Differentiation - drug effects | Glucose - metabolism | Cell Proliferation - drug effects | Mice | Primary Cell Culture | Osteoblasts - metabolism | Glucose transporter | Bone morphogenetic protein 2 | mRNA | Glucose | Metabolism | Protein turnover | Ossification | Proteins | Cartilage | Glucose metabolism | Signaling | Clonal deletion | Chondrocytes | Deletion | Bone morphogenetic proteins | Skeleton | Chondrogenesis | Growth factors | Transporter | Bone (endochondral) | Hypertrophy | Recombinant | Index Medicus
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 09/2017, Volume 172, pp. 160 - 165
Excess androgen and insulin-like growth factor (IGF)-I in the ovarian follicle has been suggested to be involved in the pathophysiology of polycystic ovary... 
Granulosa cells | Bone morphogenetic protein (BMP) | Insulin-like growth factor (IGF)-I | Steroidogenesis | Androgen | Follicle-stimulating hormone (FSH) | OOCYTE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INVOLVEMENT | MORPHOGENETIC PROTEIN SYSTEM | MITOSIS | WOMEN | HORMONE | ENDOCRINOLOGY & METABOLISM | ESTROGEN | GROWTH-DIFFERENTIATION FACTOR-9 | EXPRESSION | FOLLICULOGENESIS | Receptor, IGF Type 1 - metabolism | Insulin-Like Growth Factor I - pharmacology | Progesterone - agonists | Bone Morphogenetic Protein Receptors - genetics | Receptors, Androgen - metabolism | Cytochrome P-450 Enzyme System - metabolism | Insulin-Like Growth Factor I - genetics | Phosphoproteins - metabolism | Granulosa Cells - drug effects | Granulosa Cells - metabolism | Follicle Stimulating Hormone - pharmacology | Bone Morphogenetic Protein 1 - genetics | Dihydrotestosterone - pharmacology | Female | Hydroxysteroid Dehydrogenases - metabolism | Progesterone - biosynthesis | Transcription, Genetic | Bone Morphogenetic Protein 1 - metabolism | Phosphorylation - drug effects | Cyclic AMP - metabolism | Follicle Stimulating Hormone - genetics | Follicle Stimulating Hormone - metabolism | Signal Transduction | Gene Expression Regulation | Bone Morphogenetic Protein Receptors - metabolism | Rats | Smad Proteins - genetics | Hydroxysteroid Dehydrogenases - genetics | Phosphoproteins - genetics | Inhibitor of Differentiation Protein 1 - metabolism | Rats, Sprague-Dawley | Receptor, IGF Type 1 - genetics | Animals | Receptors, Androgen - genetics | Cytochrome P-450 Enzyme System - genetics | Inhibitor of Differentiation Protein 1 - genetics | Primary Cell Culture | Smad Proteins - metabolism | Insulin-Like Growth Factor I - metabolism | Granulosa Cells - cytology | Proteins | Follicle-stimulating hormone | Stein-Leventhal syndrome | Estrogen | Cytochrome P-450 | Luteinizing hormone | Bone morphogenetic proteins | Progesterone | Transforming growth factors | Bone morphogenetic protein 6 | Polycystic ovary syndrome | Phosphorylation | Id1 protein | Transcription | Insulin-like growth factor I | Effects | Insulin | Androgens | Dihydrotestosterone | Id protein | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2011, Volume 408, Issue 1, pp. 25 - 31
Journal Article
Human Mutation, ISSN 1059-7794, 02/2012, Volume 33, Issue 2, pp. 343 - 350
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2009, Volume 284, Issue 38, pp. 25879 - 25888
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, pp. e113419 - e113419
Dental-pulp tissue is often exposed to inflammatory injury. Sequested growth factors or angiogenic signaling proteins that are released following inflammatory... 
SIDE POPULATION | ACTIVATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | NECROSIS-FACTOR-ALPHA | INDUCTION | LIPOPOLYSACCHARIDES | NF-KAPPA-B | TNF | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Inflammation - pathology | Cell Proliferation | Humans | Neovascularization, Pathologic | NF-kappa B - metabolism | Stem Cells - cytology | Vascular Endothelial Growth Factor A - metabolism | Dental Pulp - metabolism | Telomere - drug effects | Stem Cells - metabolism | Vascular Endothelial Growth Factor A - genetics | Bone Morphogenetic Protein 1 - genetics | Inflammation - metabolism | Bone Morphogenetic Protein 2 - metabolism | Cell Differentiation | Bone Morphogenetic Protein 1 - metabolism | Membrane Glycoproteins | Osteoblasts - cytology | Dental Pulp - blood supply | Telomere Shortening - drug effects | Bone Morphogenetic Protein 2 - genetics | Osteocalcin | Transforming Growth Factor beta1 | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Osteoblasts - drug effects | Gene Expression Regulation | Bone Morphogenetic Protein Receptors, Type I - genetics | Dental Pulp - cytology | Dental Pulp - drug effects | Bone Morphogenetic Protein Receptors, Type I - metabolism | Bone Morphogenetic Protein Receptors, Type II - metabolism | Peptides - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | NF-kappa B - genetics | Inflammation - genetics | Stem Cells - drug effects | Primary Cell Culture | Osteoblasts - metabolism | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Hostages | Inflammation | Transforming growth factors | Vascular endothelial growth factor | Stem cells | Dentin | Genomic instability | Pulp | Chronic exposure | Proteins | Angiogenesis | Biomedical materials | Mineralization | Fibroblasts | Bone morphogenetic proteins | Tumor necrosis factor-TNF | Biocompatibility | Physiology | Pretreatment | Growth factors | NF-κB protein | Cell survival | Stability | Cytokines | Exposure | Dentistry | Tumor necrosis factor-α | Survival | Studies | Dental caries | Signaling | Isoforms | Hypoxia | Differentiation | Apoptosis | Dental pulp | Index Medicus
Journal Article
Journal Article
PLoS genetics, ISSN 1553-7390, 2011, Volume 7, Issue 7, pp. e1002114 - e1002114
Journal Article