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Journal of Biological Chemistry, ISSN 0021-9258, 04/2010, Volume 285, Issue 16, pp. 12169 - 12180
Bone morphogenetic proteins (BMPs) are used clinically to induce new bone formation in spinal fusions and long bone nonunion fractures. However, large amounts... 
I RECEPTORS | CELLS | ACTIVATION | DEFECTS | INDUCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPONENTS | OSTEOGENIC PROTEIN-1 | DIFFERENTIATION | EXPRESSION | BINDING | Bone Regeneration - physiology | RNA, Small Interfering - genetics | Recombinant Fusion Proteins - pharmacology | Bone Morphogenetic Protein 7 - genetics | Humans | Cercopithecus aethiops | Molecular Sequence Data | Male | Bone Morphogenetic Protein 6 - pharmacology | RNA, Messenger - metabolism | Recombinant Fusion Proteins - metabolism | Bone Morphogenetic Protein 6 - genetics | Protein Engineering | Cell Differentiation | Protein Interaction Domains and Motifs | Osteoblasts - cytology | Carrier Proteins - physiology | Amino Acid Sequence | Cell Line | Rabbits | Gene Expression | Osteogenesis - drug effects | RNA, Messenger - genetics | Carrier Proteins - antagonists & inhibitors | Mesenchymal Stromal Cells - metabolism | Models, Molecular | Sequence Homology, Amino Acid | Carrier Proteins - genetics | Feedback, Physiological | Animals | Recombinant Fusion Proteins - genetics | Lysine - chemistry | COS Cells | Bone Morphogenetic Protein 6 - physiology | Bone Morphogenetic Protein 7 - pharmacology | Noggin | Protein Structure and Folding | Bone Morphogenetic Protein (BMP) | Transforming Growth Factor Beta (TGFbeta) | Regeneration | Receptor Serine Threonine Kinase | Bone | Differentiation
Journal Article
Immunology, ISSN 0019-2805, 09/2009, Volume 128, Issue 1pt2, pp. e442 - e450
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40465
Hepcidin, a liver-derived iron regulatory protein, plays a crucial role in iron metabolism. It is known that gender differences exist with respect to iron... 
CELLS | IRON-METABOLISM | SERUM HEPCIDIN | MESSENGER-RNA | MECHANISM | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ESTRADIOL | RECEPTOR | MICE | G-PROTEIN | RNA, Small Interfering - genetics | Estradiol - analogs & derivatives | Receptors, Estrogen - metabolism | Estrogens - pharmacology | Receptors, G-Protein-Coupled - metabolism | Humans | Transcriptional Activation | Hepatocytes - metabolism | Receptors, G-Protein-Coupled - agonists | Antimicrobial Cationic Peptides - metabolism | RNA, Messenger - metabolism | Intestinal Absorption | Fulvestrant | Gene Knockdown Techniques | Bone Morphogenetic Protein 6 - genetics | Cation Transport Proteins - metabolism | Hepcidins | Duodenum - metabolism | Female | Antimicrobial Cationic Peptides - blood | Antimicrobial Cationic Peptides - genetics | Estradiol - pharmacology | Estradiol - physiology | Iron - blood | Estrogens - physiology | Receptors, Estrogen - agonists | Receptors, Estrogen - genetics | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Iron - metabolism | Hep G2 Cells | Animals | Bone Morphogenetic Protein 6 - metabolism | Liver - cytology | Mice | Receptors, G-Protein-Coupled - genetics | Phenols | Bone morphogenetic proteins | RNA | Estradiol | Liver | Blood proteins | Iron regulatory protein | Oxidative stress | G protein-coupled receptors | Estrogens | Menopause | Sex | Estrogen | Iron | Hormones | Gender | Proteins | Osteoporosis | Angiogenesis | Child development | Rodents | Gender aspects | Tumor necrosis factor-TNF | Supplementation | Localization | Protein transport | Bone morphogenetic protein 6 | Polycystic ovary syndrome | Duodenum | Ovariectomy | Sex differences | Inflammation | siRNA | Pharmacology | Metabolism | Gene expression | Augmentation | Sex hormones | Signaling | Bone cancer | Hepatocytes | Womens health | Calcification | Protein expression | In vivo methods and tests | Hepcidin | Steroid hormones | Apoptosis
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 44, pp. 17991 - 18005
The neuroligin (Nlg) family of neural cell adhesion molecules is thought to be required for synapse formation and development and has been linked to the... 
development | INHIBITORY SYNAPSES | Drosophila | BIOCHEMISTRY & MOLECULAR BIOLOGY | bone morphogenetic protein (BMP) | NMJ | HOMOLOG GBB | BETA | TRANSMISSION | neurodevelopment | NEUREXIN | EXCITATORY SYNAPSES | II RECEPTOR | Neuroligin 4 | synaptic plasticity | DIFFERENTIATION | MUTATIONS | EXPRESSION | Neuromuscular Junction - metabolism | Protein Multimerization | Green Fluorescent Proteins - genetics | Drosophila Proteins - agonists | Presynaptic Terminals - ultrastructure | Drosophila Proteins - metabolism | Neurogenesis | Recombinant Fusion Proteins - metabolism | Synaptic Transmission | Bone Morphogenetic Proteins - metabolism | Presynaptic Terminals - enzymology | Synapses - metabolism | Bone Morphogenetic Protein Receptors, Type I - agonists | Cell Adhesion Molecules, Neuronal - metabolism | Neuromuscular Junction - enzymology | Protein-Serine-Threonine Kinases - metabolism | Recombinant Proteins - metabolism | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Transmission | Signal Transduction | Animals, Genetically Modified | Receptors, Cell Surface - metabolism | Synapses - enzymology | Synapses - ultrastructure | Bone Morphogenetic Protein Receptors, Type I - metabolism | Gene Knockout Techniques | Nerve Tissue Proteins - genetics | Neuromuscular Junction - ultrastructure | Cell Adhesion Molecules, Neuronal - genetics | Nerve Tissue Proteins - metabolism | Animals | Presynaptic Terminals - metabolism | Drosophila Proteins - genetics | Mutation | Drosophila melanogaster | Microscopy, Fluorescence | Developmental Biology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 7, pp. 3395 - 3410
By non-covalent association after proteolytic cleavage, the pro-domains modulate the activities of the mature growth factor domains across the transforming... 
SUPPRESSES TUMOR-GROWTH | HEREDITARY HEMORRHAGIC TELANGIECTASIA | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRODOMAIN | bone morphogenetic protein (BMP) | surface plasmon resonance (SPR) | BMP9 | protein complex | IDENTIFICATION | MESENCHYMAL STEM-CELLS | homeostasis | transforming growth factor (TGF-B) | KINASE 1 ALK1 | MUTATIONS | TGF-BETA-1 | Activin Receptors, Type II - metabolism | Growth Differentiation Factor 2 - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Protein Precursors - blood | Protein Precursors - chemistry | Humans | Growth Differentiation Factors - blood | Antigens, CD - genetics | Recombinant Fusion Proteins - metabolism | Antigens, CD - metabolism | Endoglin | Human Umbilical Vein Endothelial Cells - cytology | HEK293 Cells | Female | Growth Differentiation Factors - genetics | Receptors, Cell Surface - chemistry | Antigens, CD - chemistry | Protein Interaction Domains and Motifs | Dimerization | Growth Differentiation Factor 2 - blood | Peptide Fragments - genetics | Activin Receptors, Type II - chemistry | Recombinant Proteins - metabolism | Growth Differentiation Factor 2 - isolation & purification | Peptide Fragments - metabolism | Protein Precursors - genetics | Specific Pathogen-Free Organisms | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Peptide Fragments - isolation & purification | Cells, Cultured | Models, Molecular | Receptors, Cell Surface - metabolism | Recombinant Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Bone Morphogenetic Protein Receptors, Type II - metabolism | Protein Precursors - metabolism | Growth Differentiation Factors - metabolism | Animals | Peptide Fragments - agonists | Activin Receptors, Type II - genetics | Mice, Inbred BALB C | Bone Morphogenetic Protein Receptors, Type II - chemistry | Growth Differentiation Factors - chemistry | Receptors, Cell Surface - genetics | transforming growth factor β (TGF-B) | Cell Biology
Journal Article
Cellular Signalling, ISSN 0898-6568, 04/2013, Volume 25, Issue 4, pp. 717 - 728
BMP-9 is a potent osteogenic factor; however, its effects on osteoclasts, the bone-resorbing cells, remain unknown. To determine the effects of BMP-9 on... 
Human osteoclast | Smad | BMP receptors | BMP-9 | Apoptosis | ERK | MEDIATES APOPTOSIS | TGF-BETA | CANCER CELLS | PULMONARY ARTERIAL-HYPERTENSION | OSTEOGENIC DIFFERENTIATION | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | SIGNAL-TRANSDUCTION | RECEPTOR-LIKE KINASE-1 | ENDOTHELIAL-CELLS | Phosphorylation | Caspase 9 - metabolism | Growth Differentiation Factor 2 - metabolism | Humans | Caspase 8 - metabolism | Growth Differentiation Factor 2 - genetics | Recombinant Proteins - biosynthesis | Osteoclasts - cytology | RANK Ligand - pharmacology | RNA Interference | Macrophage Colony-Stimulating Factor - pharmacology | Bone Morphogenetic Protein Receptors, Type II - antagonists & inhibitors | Macrophage Colony-Stimulating Factor - genetics | BH3 Interacting Domain Death Agonist Protein - metabolism | Cell Survival - drug effects | Bone Resorption | Bone Morphogenetic Protein Receptors, Type II - genetics | Cells, Cultured | Macrophage Colony-Stimulating Factor - metabolism | Recombinant Proteins - genetics | Fetal Blood - cytology | Recombinant Proteins - pharmacology | Osteoclasts - metabolism | Bone Morphogenetic Protein Receptors, Type II - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Leukocytes, Mononuclear - cytology | Smad Proteins - metabolism | Osteoclasts - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Bone morphogenetic proteins | Macrophage colony stimulating factor
Journal Article
Biochemical Society Transactions, ISSN 0300-5127, 10/2015, Volume 43, Issue 5, pp. 795 - 800
Journal Article
Cell Stem Cell, ISSN 1934-5909, 2010, Volume 7, Issue 1, pp. 78 - 89
Journal Article
Journal Article
Trends in Endocrinology & Metabolism, ISSN 1043-2760, 2014, Volume 25, Issue 9, pp. 464 - 471
Journal Article