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American journal of respiratory cell and molecular biology, ISSN 1044-1549, 08/2016, Volume 55, Issue 2, pp. 201 - 212
Human immunodeficiency virus (HIV)-related pulmonary arterial hypertension has been found to be more prevalent in intravenous drug users... 
Pulmonary hypertension; drug abuse; smooth muscle; bone morphogenetic protein receptor; human immunodeficiency virus-1 | bone morphogenetic protein receptor | OXIDATIVE STRESS | RISK-FACTORS | pulmonary hypertension | BIOCHEMISTRY & MOLECULAR BIOLOGY | smooth muscle | DOWN-REGULATION | MUSCLE-CELLS | CELL BIOLOGY | human immunodeficiency virus-1 | IN-VITRO | drug abuse | RESPIRATORY SYSTEM | ARTERIAL-HYPERTENSION | HIV-1 TAT | TYPE-1 TAT PROTEIN | EXPRESSION | MORPHOGENETIC PROTEIN-RECEPTOR | HIV - physiology | Apoptosis - drug effects | Humans | Rats, Inbred F344 | Myocytes, Smooth Muscle - pathology | Systole - drug effects | Male | Viral Proteins - metabolism | HIV - drug effects | Lung - virology | Blood Pressure - drug effects | Lung - metabolism | Vascular Remodeling - drug effects | Cocaine - adverse effects | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Rats, Transgenic | Cell Separation | Bone Morphogenetic Protein Receptors - metabolism | Lung - physiopathology | Pulmonary Artery - physiopathology | Pulmonary Artery - drug effects | Down-Regulation - drug effects | Rats, Sprague-Dawley | Muscle, Smooth, Vascular - pathology | Animals | Signal Transduction - drug effects | Lung - drug effects | Cell Proliferation - drug effects | Hemodynamics - drug effects | Hypertension | Heart | Pulmonary arteries | Laboratories | Diagnostic tests | Mortality | Smooth muscle | Infections | Proteins | Hepatitis | Rodents | Human immunodeficiency virus--HIV | Protein expression | Cocaine | Intubation | Apoptosis
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 77, pp. 280 - 290
... ) and non-classical anti-inflammatory monocytes (AMs, Ly6Clo Gr1− CX3CR1hi ). Drug-eluting biomaterial implants can be used to tune the endogenous repair process by the preferential recruitment of pro-regenerative cells... 
Advanced Basic Science | Dentistry | SDF-1 | Angiogenesis | Arteriogenesis | Hydrogel | Immunomodulation | Vascularization | PROGENITOR CELLS | BIOACTIVITY | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | MACROPHAGES | REGENERATION | SUBSETS | HEPARIN | IDENTIFICATION | SPHINGOSINE 1-PHOSPHATE | Neovascularization, Physiologic - drug effects | Hydrogels | Bone Marrow Cells - physiology | Male | Green Fluorescent Proteins - genetics | Flow Cytometry | Chemotaxis, Leukocyte - drug effects | Arterioles - growth & development | Bone Marrow Cells - drug effects | Monocytes - physiology | Wound Healing - drug effects | Chemokine CXCL12 - administration & dosage | Genes, Reporter | Intravital Microscopy | Polyethylene Glycols | Mice, Inbred C57BL | Cells, Cultured | Skin Window Technique | Arterioles - ultrastructure | Mice, Transgenic | Inflammation | Radiation Chimera | Recombinant Proteins - pharmacology | Recombinant Proteins - administration & dosage | Monocytes - drug effects | Microvessels - physiology | Neovascularization, Physiologic - physiology | Animals | Chemokine CXCL12 - pharmacology | Mice | Wound Healing - physiology | Heparin | Surgical implants | Networks | Biomedical materials | Correlation | Remodeling | Recruitment | Biomaterials | immunomodulation | hydrogel | angiogenesis | arteriogenesis
Journal Article
Journal Article
Journal of neuroinflammation, ISSN 1742-2094, 2015, Volume 12, Issue 1, pp. 26 - 26
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2016, Volume 92, pp. 96 - 104
Journal Article
Journal Article
Journal of bone and mineral research, ISSN 0884-0431, 2011, Volume 26, Issue 11, pp. 2727 - 2736
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2010, Volume 207, Issue 13, pp. 2793 - 2798
Sphingosine-1-phosphate (S1P), a lipid mediator enriched in blood, controls the dynamic migration of osteoclast (OC) precursors (OPs) between the blood and... 
MEDICINE, RESEARCH & EXPERIMENTAL | MARROW | CELL-MIGRATION | CHEMOKINE | SPHINGOSINE-1-PHOSPHATE RECEPTORS | IMMUNOLOGY | EXPRESSION | T-CELLS | SPHINGOSINE 1-PHOSPHATE | Receptors, Lysosphingolipid - antagonists & inhibitors | RANK Ligand - metabolism | Recombinant Fusion Proteins - pharmacology | Receptors, Lysosphingolipid - deficiency | Green Fluorescent Proteins - genetics | Stem Cells - cytology | Osteoclasts - cytology | Stem Cells - metabolism | Recombinant Fusion Proteins - metabolism | Bone Remodeling - drug effects | Bone and Bones - drug effects | RANK Ligand - pharmacology | Flow Cytometry | Glutathione Transferase - genetics | RNA Interference | Bone and Bones - metabolism | Lysophospholipids - pharmacology | Receptors, Lysosphingolipid - genetics | Receptors, Chemokine - genetics | Bone and Bones - cytology | Pyrazoles - pharmacology | Cell Line | Green Fluorescent Proteins - metabolism | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Cells, Cultured | Glutathione Transferase - metabolism | Mice, Transgenic | Lysophospholipids - blood | Chemotaxis - drug effects | Osteoclasts - metabolism | Mice, Knockout | RANK Ligand - genetics | Sphingosine - pharmacology | Cell Movement - drug effects | Glutathione Transferase - pharmacology | Sphingosine - analogs & derivatives | Animals | Microscopy, Fluorescence - methods | Recombinant Fusion Proteins - genetics | Sphingosine - blood | Stem Cells - drug effects | Mice | Pyridines - pharmacology | CX3C Chemokine Receptor 1 | Osteoclasts - drug effects | Brief Definitive Report
Journal Article
Nature cell biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 224 - 234
Parathyroid hormone (PTH) regulates calcium homeostasis and bone metabolism by activating PTH type I receptor (PTH1R). Here we show that transforming growth... 
(PTH)/PTH-RELATED PEPTIDE | LINKED RECEPTOR | TRABECULAR BONE | GROWTH-FACTOR-BETA | PARATHYROID-HORMONE RECEPTOR | PROTEIN-COUPLED RECEPTOR | CRYSTAL-STRUCTURE | TRANSFORMING GROWTH-FACTOR-BETA-1 | RENAL-FAILURE | EXPRESSION CLONING | CELL BIOLOGY | RNA, Small Interfering - genetics | Receptors, Transforming Growth Factor beta - genetics | RANK Ligand - metabolism | Leg Bones - pathology | Receptor, Parathyroid Hormone, Type 1 - metabolism | Gene Expression - genetics | Cell Count | Humans | Leg Bones - drug effects | Male | Bone Density - genetics | Bone Remodeling - physiology | Mutation - physiology | Osteocalcin - blood | Parathyroid Hormone - metabolism | Protein Binding - drug effects | Protein Multimerization - physiology | Phosphorylation - drug effects | Cyclic AMP - metabolism | Protein-Serine-Threonine Kinases - metabolism | Osteoclasts - pathology | Endocytosis - drug effects | Mice, Knockout | Signal Transduction - drug effects | beta-Arrestins | Receptor, Parathyroid Hormone, Type 1 - genetics | Mice | Protein Multimerization - drug effects | Protein Binding - physiology | Collagen Type I - blood | Phosphorylation - physiology | Peptides - blood | Protein Interaction Domains and Motifs - physiology | Arrestins - genetics | Parathyroid Hormone - pharmacology | Peptide Fragments - pharmacology | Arrestins - metabolism | Bone Remodeling - drug effects | Receptor, Transforming Growth Factor-beta Type II | Endocytosis - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Parathyroid Hormone - antagonists & inhibitors | Osteoblasts - pathology | Animals | Receptors, Transforming Growth Factor beta - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Signal Transduction - physiology | Osteoblasts - metabolism | Smad Proteins - metabolism
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 4/2013, Volume 110, Issue 18, pp. 7336 - 7341
TGF-β is abundantly produced in the skeletal system and plays a crucial role in skeletal homeostasis. E-selectin ligand-1 (ESL-1), a Golgi apparatus-localized... 
Bone resorption | Femur | Receptors | Metabolic bone diseases | Homeostasis | Antibodies | Bones | Gene expression regulation | Bone remodeling | Bioavailability | Osteoporosis | Osteoblast mineralization | 1D11 antibody | TRANSFORMING GROWTH-FACTOR-BETA-1 PRECURSOR | COMPLEX | ACTIVATION | MULTIDISCIPLINARY SCIENCES | BINDING-PROTEIN | FIBROBLAST-GROWTH-FACTOR | FURIN | osteoporosis | IDENTIFICATION | FACTOR RECEPTOR | INHIBITION | osteoblast mineralization | MARFAN-SYNDROME | Femur - pathology | Sialoglycoproteins - metabolism | Receptors, Fibroblast Growth Factor - deficiency | Bone Diseases, Metabolic - pathology | Gene Expression Profiling | Femur - diagnostic imaging | Cell Lineage - drug effects | Bone Remodeling - drug effects | Cell Differentiation - genetics | Bone Diseases, Metabolic - complications | Bone Resorption - genetics | Homeostasis - drug effects | Cell Lineage - genetics | Osteogenesis - genetics | Calcification, Physiologic - genetics | Bone Resorption - physiopathology | Osteoclasts - pathology | Calcification, Physiologic - drug effects | Osteoblasts - drug effects | Osteogenesis - drug effects | Cells, Cultured | Femur - drug effects | Bone Resorption - complications | Signal Transduction - genetics | Femur - physiopathology | Osteoclasts - metabolism | Antibodies - pharmacology | Bone Diseases, Metabolic - metabolism | Gene Expression Regulation - drug effects | Radiography | Osteoblasts - pathology | Organ Size - drug effects | Phenotype | Animals | Cell Differentiation - drug effects | Receptors, Fibroblast Growth Factor - metabolism | Bone Resorption - pathology | Mice | Bone Remodeling - genetics | Bone Diseases, Metabolic - physiopathology | Osteoblasts - metabolism | Transforming Growth Factor beta - metabolism | Osteoclasts - drug effects | Sialoglycoproteins - deficiency | Biological Sciences
Journal Article