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NATURE MEDICINE, ISSN 1078-8956, 03/2013, Volume 19, Issue 3, pp. 276 - 277
... recurrences by targeting residual disseminated tumor cells (DTCs) that give origin to metastasis, as well as existing undetected micrometastasis. Whereas in some cases... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE | TUMOR-CELL QUIESCENCE | CELL BIOLOGY | Genetic aspects | Research | Metastasis | Drug therapy | Health aspects | Cancer cells
Journal Article
Nature medicine, ISSN 1078-8956, 2017, Volume 23, Issue 9, pp. 1072 - 1079
Aging is associated with increased cellular senescence, which is hypothesized to drive the eventual development of multiple comorbidities(1). Here we... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | SECRETORY PHENOTYPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MATURE | IDENTIFICATION | CELL BIOLOGY | OSTEOCLASTOGENESIS | ACTIVATOR | MASS | ESTROGEN | FRACTURES | DYSFUNCTION | Osteocytes - drug effects | Cancellous Bone - metabolism | beta-Galactosidase | Cellular Senescence - drug effects | Apoptosis - genetics | Cancellous Bone - drug effects | Gene Expression Profiling | Osteoclasts - cytology | Bone and Bones - drug effects | Caspase 8 - genetics | Flow Cytometry | Osteoporosis - metabolism | Bone and Bones - metabolism | Osteoporosis - genetics | Cell Differentiation | Osteoblasts - cytology | Real-Time Polymerase Chain Reaction | Pyrazoles - pharmacology | Cellular Senescence - genetics | Osteoblasts - drug effects | Mice, Transgenic | Absorptiometry, Photon | Cortical Bone - metabolism | Janus Kinases - antagonists & inhibitors | Culture Media, Conditioned | Animals | Cortical Bone - drug effects | Weight-Bearing | Mice | In Vitro Techniques | Osteoclasts - drug effects | Prevention | Osteoporosis | Aging | Physiological aspects | Genetic aspects | Research | Cells | Senescence | Bone (trabecular) | Suicide | Bone resorption | Bone growth | Biomedical materials | Mineralization | Rodents | Computer architecture | Biocompatibility | Inhibition | Conditioning | Bone loss | Bone (cortical) | Suicide genes | Age | Cardiovascular system | Cell survival | Aging (artificial) | Caspase | Pharmacology | Secretome | Inflammation | Insulin | Osteoclastogenesis | Caspase-8 | Bone mass | Cellular biology | Sensitivity enhancement | In vitro methods and tests | Osteogenesis | Disease prevention | Osteoclast | Drug therapy | Osteocyte
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 435 - 11
...ARTICLE Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells Naohiro Seo1,2, Yoshitaka Shirakura1... 
ENDOTHELIAL PROGENITOR CELLS | BREAST-CANCER CELLS | ADHESION | STEM-CELLS | IMMUNOTHERAPY | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | IN-VIVO | EXOSOMES | MICROENVIRONMENTAL REGULATION | STROMAL CELLS | Mesenchyme | Toxicity | CD8 antigen | Invasiveness | Stem cell transplantation | Cytotoxicity | Lymphocytes T | Cell density | Metastases | Vesicles | Depletion | Lymphocytes | Stromal cells | Stem cells | Fibroblasts | Infiltration | Cancer | Tumors | Apoptosis
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 2012, Volume 586, Issue 19, pp. 3255 - 3262
... on osteoclast differentiation. ► miR-155 inhibited osteoclast differentiation by targeting Socs1 and Mitf. IFN-β... 
Osteoclast differentiation | microRNA | MITF | IFN-β | SOCS1 | miR-155 | 3′UTRs | RANKL | interferon-β | TRAP | tartrate-resistant acid phosphatase | BMMs | 3′untranslated regions | microphthalmia-associated transcription factor | suppressor of cytokine signaling1 | bone marrow-derived macrophages | receptor activator of NF-κB ligand | miRNA | IFN-beta | C-FOS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYTOKINE | KAPPA-B | MICRORNA-155 | CELL BIOLOGY | BONE LOSS | BIOPHYSICS | GENE | REGULATE OSTEOCLASTOGENESIS | OSTEOPROTEGERIN LIGAND | RECEPTOR ACTIVATOR | T-CELLS | RANK Ligand - metabolism | Humans | Suppressor of Cytokine Signaling 1 Protein | Osteoclasts - cytology | Cell Differentiation - genetics | Bone Resorption - genetics | Base Sequence | HEK293 Cells | Bone Resorption - metabolism | Interferon-beta - genetics | 3' Untranslated Regions | Cell Differentiation - physiology | Cell Line | Microphthalmia-Associated Transcription Factor - metabolism | Signal Transduction | Down-Regulation | Mice, Inbred C57BL | Suppressor of Cytokine Signaling Proteins - genetics | MicroRNAs - biosynthesis | Recombinant Proteins - pharmacology | Osteoclasts - metabolism | Sequence Homology, Nucleic Acid | Mice, Knockout | Animals | Interferon-beta - pharmacology | Cell Differentiation - drug effects | Bone Resorption - pathology | Mice | MicroRNAs - genetics | Suppressor of Cytokine Signaling Proteins - metabolism | Microphthalmia-Associated Transcription Factor - genetics | Interferon-beta - deficiency | Osteoclasts - drug effects
Journal Article