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PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e81341
There is increasing evidence that complement may play a role in bone development. Our previous studies demonstrated that the key complement receptor C5aR was... 
OSTEOCLASTOGENESIS | ACTIVATION | C1S | MULTIDISCIPLINARY SCIENCES | OSSIFICATION CENTER | OSTEOBLASTS | MECHANISMS | GENERATION | BONE | DIFFERENTIATION | EXPRESSION | Bony Callus - immunology | Elasticity | Male | Bony Callus - pathology | Femur - diagnostic imaging | Complement C3a - genetics | X-Ray Microtomography | Fractures, Bone - genetics | Bony Callus - diagnostic imaging | Gene Deletion | Gene Expression - immunology | Fractures, Bone - diagnostic imaging | Complement C5a - deficiency | Femur - injuries | Fractures, Bone - immunology | Complement C3a - deficiency | Hardness | Interleukin-6 - secretion | Fracture Healing - immunology | Complement Activation - genetics | Biomechanical Phenomena | Animals | Interleukin-6 - biosynthesis | Complement C5a - genetics | Mice | Complement C3a - immunology | Complement C5a - immunology | Fracture Healing - genetics | Fractures | Research | Femur | Callus | Osteotomy | Complement component C5a | Complement | Proteins | Biomedical materials | Immunology | Computed tomography | Rodents | Tomography | Biocompatibility | Stiffness | Repair | Immune system | Cytokines | Chondroblasts | Plastic surgery | Bone healing | Trauma | Biomechanics | Studies | Complement activation | Complement component C5 | Complement component C3 | Sepsis | Healing | Regulation | Clinical medicine | Bone | Laboratory animals | Biological Sciences | Naturvetenskap | Biomedical Sciences | Biokemi och molekylärbiologi | Biologiska vetenskaper | Biochemistry and Molecular Biology | Natural Sciences | Biomedicinsk vetenskap
Journal Article
BMC Musculoskeletal Disorders, ISSN 1471-2474, 06/2017, Volume 18, Issue 1, pp. 253 - 10
Background: Heightened local inflammation due to muscle trauma or disease is associated with impaired bone regeneration. Methods: We hypothesized that FK506,... 
Composite injury | Open fracture | Orthopaedic trauma | Tacrolimus | Immunomodulation | Adaptive immune response | Inflammation | Volumetric muscle loss | Musculoskeletal | Skeletal muscle injury | DOSE-DEPENDENCE | AXONAL REGENERATION | INDUCTION | MODEL | RHEUMATOLOGY | CYCLOSPORINE-A | IMMUNE-SYSTEM | IMMUNOSUPPRESSION | BONE REGENERATION | ORTHOPEDICS | T-CELLS | Bony Callus - immunology | Bony Callus - drug effects | Torque | Bone Nails | Osteotomy | Humans | Immunosuppressive Agents - therapeutic use | Soft Tissue Injuries - immunology | Rats, Inbred Lew | Soft Tissue Injuries - drug therapy | Male | Bony Callus - pathology | Muscle, Skeletal - injuries | Tibial Fractures - surgery | Tibial Fractures - drug therapy | Fracture Healing - drug effects | Soft Tissue Injuries - complications | Tibial Fractures - physiopathology | T-Lymphocytes - drug effects | Muscle, Skeletal - drug effects | Muscular Diseases - drug therapy | Tacrolimus - pharmacology | Fracture Fixation, Intramedullary - instrumentation | Immunosuppressive Agents - pharmacology | Macrophages - immunology | Disease Models, Animal | Bone Regeneration - drug effects | Immunity, Innate - drug effects | Rats | Muscular Diseases - pathology | Soft Tissue Injuries - pathology | Tacrolimus - therapeutic use | Fracture Fixation, Intramedullary - methods | Muscular Diseases - immunology | Adaptive Immunity - drug effects | Animals | Biopsy | Muscular Diseases - complications | Macrophages - drug effects | T-Lymphocytes - immunology | Muscle, Skeletal - pathology | Callus | Cytokines | Mechanical properties | Arthritis | Lymphocytes T | Bone healing | Gene expression | Macrophages | Trauma | Muscle contraction | Skeletal muscle | Regeneration | Bone growth | Fractures | Tibia | Lymphocytes | Stem cells | Laboratory animals | Growth factors
Journal Article
Journal of Hand Surgery, ISSN 0363-5023, 2004, Volume 29, Issue 6, pp. 1020 - 1027
Little is known about bone healing after composite tissue transplantation that requires pharmacologic immunosuppression. Bone integration and callus... 
composite tissue transplantation | hand transplantation | immunosuppression | Bone healing | SURGERY | ANTIGENICITY | TOLERANCE | TISSUE | RATS | FOLLOW-UP | FK506 | RECIPIENTS | LIMB ALLOGRAFT | CYCLOSPORINE-A | bone healing | MASS | ORTHOPEDICS | Bony Callus - immunology | Neovascularization, Physiologic - drug effects | Prednisolone - adverse effects | Bony Callus - drug effects | Forearm Injuries - diagnostic imaging | Forearm Injuries - immunology | Hand Injuries - immunology | Follow-Up Studies | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Blast Injuries - surgery | Hand - blood supply | Surgical Flaps - blood supply | Hand Injuries - surgery | Fracture Healing - drug effects | Bony Callus - diagnostic imaging | Prednisolone - therapeutic use | Drug Therapy, Combination | Replantation | Bone Regeneration - drug effects | Amputation, Traumatic - immunology | Ultrasonography, Doppler | Amputation, Traumatic - surgery | Forearm Injuries - surgery | Bony Callus - blood supply | Tacrolimus - adverse effects | Blast Injuries - diagnostic imaging | Hand Injuries - diagnostic imaging | Hand Transplantation | Mycophenolic Acid - adverse effects | Tacrolimus - therapeutic use | Amputation, Traumatic - diagnostic imaging | Mycophenolic Acid - analogs & derivatives | Mycophenolic Acid - therapeutic use | Immunosuppressive Agents - adverse effects | Blast Injuries - immunology
Journal Article
Acta Orthopaedica, ISSN 1745-3674, 1992, Volume 63, Issue 3, pp. 318 - 322
Journal Article
International Archives of Allergy and Immunology, ISSN 1018-2438, 1983, Volume 71, Issue 3, pp. 200 - 209
Normal human sera contain stratum corneum (SC) antibodies to two biochemically distinct antigens of normal skin as demonstrated by indirect immunofluorescence... 
Bony Callus - immunology | Glycoproteins - immunology | Animals | Antigens - analysis | Humans | Antibodies - analysis | Fluorescent Antibody Technique | Anthralin - therapeutic use | Carbohydrates - immunology | Trypsin - therapeutic use | Haplorhini | Skin - immunology
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