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1. Full Text Treatment of HAE Attacks in the Icatibant Outcome Survey: An Analysis of Icatibant Self-Administration versus Administration by Health Care Professionals
by Hernández Fernandez de Rojas, Dolores and Ibañez, Ethel and Longhurst, Hilary and Maurer, Marcus and Fabien, Vincent and Aberer, Werner and Bouillet, Laurence and Zanichelli, Andrea and Caballero, Teresa and IOS Study Grp and IOS Study Group and on behalf of the IOS Study Group
International archives of allergy and immunology, ISSN 1018-2438, 07/2015, Volume 167, Issue 1, pp. 21 - 28
Original Paper | Hereditary angio-oedema | Self-administration | Therapy | Icatibant Outcome Survey | Bradykinin B2 receptor antagonist | Oedema | C1 inhibitor deficiency | Icatibant | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Bradykinin - analogs & derivatives | Bradykinin - therapeutic use | Prospective Studies | Bradykinin B2 Receptor Antagonists - administration & dosage | Bradykinin - adverse effects | Humans | Middle Aged | Male | Treatment Outcome | Data Collection | Bradykinin B2 Receptor Antagonists - therapeutic use | Young Adult | Bradykinin B2 Receptor Antagonists - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Adolescent | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Adult | Female | Aged | Retrospective Studies | Angioedemas, Hereditary - drug therapy | Bradykinin - administration & dosage | Self Administration - adverse effects | Skin diseases | Antagonist drugs | Allergies | Clinical outcomes | Index Medicus
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2. Full Text Safety and efficacy of icatibant self‐administration for acute hereditary angioedema
by Boccon‐Gibod, I and Bouillet, L
Clinical and experimental immunology, ISSN 0009-9104, 06/2012, Volume 168, Issue 3, pp. 303 - 307
skin (dermatology) | genetics | complement | therapy/immunology | human studies | Genetics | Complement | Therapy/immunology | Skin (dermatology) | Human studies | Life Sciences & Biomedicine | Immunology | Science & Technology | Fundamental and applied biological sciences. Psychology | Immunopathology | Analytical, structural and metabolic biochemistry | Skin allergic diseases. Stinging insect allergies | Biological and medical sciences | Allergic diseases | Medical sciences | Bradykinin - analogs & derivatives | Acute Disease | Prospective Studies | Bradykinin - adverse effects | Humans | Middle Aged | Male | Disease Progression | Young Adult | Erythema - etiology | Self Administration | Bradykinin Receptor Antagonists | Quality of Life | Adult | Female | Surveys and Questionnaires | Angioedemas, Hereditary - drug therapy | Bradykinin - administration & dosage | Medical treatment | Index Medicus | Self-administration | angioedema | therapy | Original | immunology
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3. Full Text Angiotensin-(1–7)-dependent vasorelaxation of the renal artery exhibits unique angiotensin and bradykinin receptor selectivity
by Yousif, Mariam H.M and Benter, Ibrahim F and Diz, Debra I and Chappell, Mark C
Peptides (New York, N.Y. : 1980), ISSN 0196-9781, 04/2017, Volume 90, pp. 10 - 16
c-GMP | Renal artery | Kidney | Angiotensin | Endothelium | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Peptide Fragments - metabolism | Pyridines - administration & dosage | Renal Artery - pathology | Humans | Peptide Fragments - administration & dosage | Angiotensin I - administration & dosage | Imidazoles - administration & dosage | Rats | Guanylate Cyclase - metabolism | Angiotensin I - metabolism | NG-Nitroarginine Methyl Ester - administration & dosage | Phenylephrine - administration & dosage | Vasodilation - genetics | Animals | Receptors, Bradykinin - metabolism | Signal Transduction - drug effects | Receptor, Angiotensin, Type 1 - metabolism | Bradykinin Receptor Antagonists - administration & dosage | Renal Artery - metabolism | Blood Pressure - drug effects | Renal Artery - drug effects | Losartan - administration & dosage | Nitric Oxide - metabolism | Angiotensin Receptor Antagonists - administration & dosage | Blood vessels | Medical colleges | Dilatation | Bradykinin | Hypertension | Vasodilators | Index Medicus
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4. Full Text Effect of the bradykinin 1 receptor antagonist SSR240612 after oral administration in Mycobacterium tuberculosis-infected mice
by Rodrigues-Junior, Valnês S and Pail, Priscilla B and Villela, Anne D and Falcão, Virgínia C.A and Dadda, Adílio S and Abbadi, Bruno L and Pesquero, João B and Santos, Diógenes S and Basso, Luiz A and Campos, Maria M
Tuberculosis (Edinburgh, Scotland), ISSN 1472-9792, 03/2018, Volume 109, pp. 1 - 7
Tuberculosis | Kinin receptors | Drug development | SSR240612 | Respiratory System | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Bradykinin - analogs & derivatives | Lung - microbiology | Receptor, Bradykinin B2 - genetics | Tuberculosis, Pulmonary - microbiology | Receptor, Bradykinin B1 - drug effects | Tuberculosis, Pulmonary - metabolism | Bradykinin B2 Receptor Antagonists - administration & dosage | Male | Tuberculosis, Pulmonary - drug therapy | Spleen - drug effects | Tuberculosis, Pulmonary - genetics | Mycobacterium tuberculosis - drug effects | Spleen - microbiology | Receptor, Bradykinin B1 - genetics | Dioxoles - administration & dosage | Female | Lung - metabolism | Macrophages - microbiology | Disease Models, Animal | Administration, Oral | Mice, Inbred C57BL | Bacterial Load | Mice, Knockout | Macrophages - metabolism | Animals | Receptor, Bradykinin B1 - deficiency | Spleen - metabolism | Lung - drug effects | Antitubercular Agents - administration & dosage | Receptor, Bradykinin B2 - metabolism | Macrophages - drug effects | RAW 264.7 Cells | Bradykinin B1 Receptor Antagonists - administration & dosage | Mice | Receptor, Bradykinin B1 - metabolism | Bradykinin - administration & dosage | Sulfonamides - administration & dosage | Mycobacterium tuberculosis - growth & development | Animal experimentation | Immunohistochemistry | Bradykinin | Analysis | Drugs | Spleen | Splenomegaly | Animal models | Statistical analysis | Incubation | Oral administration | Antagonists | Infections | Macrophages | Lungs | Antagonist drugs | In vivo methods and tests | Index Medicus
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5. Full Text Subcutaneous Icatibant for the Treatment of Hereditary Angioedema Attacks: Comparison of Home Self-Administration with Administration at a Medical Facility
by Otani, Iris M., MD and Lumry, William R., MD and Hurwitz, Shelley, PhD and Li, Huamin Henry, MD, PhD and Craig, Timothy J., DO and Holtzman, Niki S., BA and Iandoli, Matthew I., MS and Tucker, Julie, CCRC and Riedl, Marc A., MD, MS and Zuraw, Bruce L., MD and Banerji, Aleena, MD
The journal of allergy and clinical immunology in practice (Cambridge, MA), ISSN 2213-2198, 2016, Volume 5, Issue 2, pp. 442 - 447.e1
Internal Medicine | Allergy and Immunology | Bradykinin-receptor antagonist | Hereditary angioedema | Icatibant | Home-based treatment | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Bradykinin - analogs & derivatives | United States - epidemiology | Prospective Studies | Bradykinin B2 Receptor Antagonists - administration & dosage | Humans | Middle Aged | Visual Analog Scale | Angioedemas, Hereditary - epidemiology | Bradykinin B2 Receptor Antagonists - therapeutic use | Young Adult | Self Administration | Health Personnel | Injections, Subcutaneous | Aged, 80 and over | Adult | Angioedemas, Hereditary - drug therapy | Time-to-Treatment - statistics & numerical data | Bradykinin - therapeutic use | Treatment Outcome | Patient Preference | Home Care Services | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Aged | Bradykinin - administration & dosage | Cardiovascular disease | FDA approval | Family medical history | Patients | Quality of life | Index Medicus
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6. Full Text Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema
by Aygören-Pürsün, Emel and Bygum, Anette and Grivcheva-Panovska, Vesna and Magerl, Markus and Graff, Jochen and Steiner, Urs C and Fain, Olivier and Huissoon, Aarnoud and Kinaciyan, Tamar and Farkas, Henriette and Lleonart, Ramon and Longhurst, Hilary J and Rae, William and Triggiani, Massimo and Aberer, Werner and Cancian, Mauro and Zanichelli, Andrea and Smith, William B and Baeza, Maria L and Du-Thanh, Aurelie and Gompels, Mark and Gonzalez-Quevedo, Teresa and Greve, Jens and Guilarte, Mar and Katelaris, Constance and Dobo, Sylvia and Cornpropst, Melanie and Clemons, Desiree and Fang, Lei and Collis, Phil and Sheridan, William and Maurer, Marcus and Cicardi, Marco
The New England journal of medicine, ISSN 0028-4793, 07/2018, Volume 379, Issue 4, pp. 352 - 362
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Kallikrein | Angioneurotic edema | Care and treatment | Research | Medical research | Pharmacodynamics | Internal medicine | Dermatology | Angioedema | Prophylaxis | Oral administration | Otolaryngology | Patients | Quality of life | Complement component C1 | Medicine | Design | Androgens | Immunology | Hospitals | Esterase | Collaboration | Bradykinin | Plasma kallikrein | Drug dosages | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology
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7. Full Text Analgesic and anti-inflammatory actions on bradykinin route of a polysulfated fraction from alga Ulva lactuca
by de Araújo, Ianna Wivianne Fernandes and Rodrigues, José Ariévilo Gurgel and Quinderé, Ana Luíza Gomes and Silva, Jane de Fátima Teixeira and Maciel, Gabrielle de Freitas and Ribeiro, Natássia Albuquerque and de Sousa Oliveira Vanderlei, Edfranck and Ribeiro, Kátia Alves and Chaves, Hellíada Vasconcelos and Pereira, Karuza Maria Alves and Bezerra, Mirna Marques and Benevides, Norma Maria Barros
International journal of biological macromolecules, ISSN 0141-8130, 11/2016, Volume 92, pp. 820 - 830
Seaweed | Sulfated polysaccharides | Inflammation | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Polymer Science | Science & Technology | Analgesics - pharmacology | Plant Extracts - chemistry | Serotonin - administration & dosage | Rats, Wistar | Male | Ulva - chemistry | Pain - chemically induced | Pain - drug therapy | Polysaccharides - isolation & purification | Formaldehyde - administration & dosage | Nociception - drug effects | Polysaccharides - chemistry | Anti-Inflammatory Agents - isolation & purification | Histamine - administration & dosage | Analgesics - isolation & purification | Anti-Inflammatory Agents - pharmacology | Acetic Acid - administration & dosage | Rats | Bradykinin - antagonists & inhibitors | Edema - drug therapy | Pain - pathology | Polysaccharides - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Analgesics - chemistry | Chemical Fractionation | Mice | Edema - chemically induced | Bradykinin - administration & dosage | Dextrans - administration & dosage | Edema - pathology | Carrageenan - administration & dosage | Enzymes | Carrageenin | Hydroxides | Anti-inflammatory drugs | Cellulose | Sulfates | Chromatography | Organic acids | Formaldehyde | Dextran | Histamine | Analysis | Bradykinin | Acetic acid | Index Medicus
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8. Full Text Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists
by Gary P. Van Guilder and Brian L. Stauffer and Jared J. Greiner and Christopher A. DeSouza
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2008, Volume 294, Issue 4, pp. 1685 - 1692
Intracellular signaling pathways | Nitric oxide | Cell surface receptors | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Humans | Isoproterenol - administration & dosage | Middle Aged | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Male | Endothelium, Vascular - enzymology | NG-Nitroarginine Methyl Ester - administration & dosage | Dose-Response Relationship, Drug | Enzyme Inhibitors - administration & dosage | Regional Blood Flow - drug effects | Methacholine Chloride - administration & dosage | Forearm - blood supply | Adult | Female | Body Mass Index | Muscarinic Agonists - administration & dosage | Nitroprusside - administration & dosage | Endothelium, Vascular - physiopathology | Obesity - physiopathology | Obesity - metabolism | Acetylcholine - administration & dosage | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Aged | Nitric Oxide Synthase - metabolism | Infusions, Intravenous | Vasodilation - drug effects | Bradykinin - administration & dosage | Nitric Oxide - metabolism | Vasodilator Agents - administration & dosage | Substance P - administration & dosage | Studies | Blood vessels | Obesity | Cells | Index Medicus | intracellular signaling pathways | nitric oxide | cell surface receptors
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9. Full Text Characterization of endothelium-derived hyperpolarizing factor in the human forearm microcirculation
by Julian P. J. Halcox and Suresh Narayanan and Laura Cramer-Joyce and Rita Mincemoyer and Arshed A. Quyyumi
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 06/2001, Volume 280, Issue 6, pp. 2470 - 2477
Sodium nitroprusside | Vascular tone | Bradykinin | Cytochrome P-450 | Miconazole | Potassium | Endothelium | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Microcirculation - metabolism | Cytochrome P-450 Enzyme Inhibitors | Humans | Middle Aged | Vasomotor System - drug effects | Cytochrome P-450 Enzyme System - metabolism | Microcirculation - drug effects | Aspirin - administration & dosage | Phenylephrine - administration & dosage | Dose-Response Relationship, Drug | Enzyme Inhibitors - administration & dosage | Forearm - blood supply | Adult | Potassium Chloride - administration & dosage | Forearm - physiology | Biological Factors - metabolism | Vasoconstrictor Agents - administration & dosage | Vasomotor System - metabolism | Administration, Oral | Nitroprusside - administration & dosage | Cyclooxygenase Inhibitors - administration & dosage | Miconazole - administration & dosage | omega-N-Methylarginine - administration & dosage | Bradykinin - administration & dosage | Blood Flow Velocity - physiology | Vasodilator Agents - administration & dosage | Plethysmography | Blood Flow Velocity - drug effects | Brachial Artery - physiology | Infusions, Intra-Arterial | Index Medicus
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10. Full Text Icatibant for the treatment of orolingual angioedema following the administration of tissue plasminogen activator
by Brown, Emily and Campana, Christina and Zimmerman, Jacob and Brooks, Steven
The American journal of emergency medicine, ISSN 0735-6757, 06/2018, Volume 36, Issue 6, pp. 1125.e1 - 1125.e2
Stroke | Airway management | Tissue plasminogen activator | Icatibant | Angioedema | Life Sciences & Biomedicine | Emergency Medicine | Science & Technology | Bradykinin - analogs & derivatives | Humans | Middle Aged | Tissue Plasminogen Activator - administration & dosage | Treatment Outcome | Stroke - drug therapy | Stroke - physiopathology | Tissue Plasminogen Activator - adverse effects | Angioedema - drug therapy | Angioedema - chemically induced | Female | Bradykinin - administration & dosage | Emergency Medical Services | Hypertension | Myocardial infarction | Fibrin | Regulatory agencies | Activation | Kininogens | Patients | t-Plasminogen activator | Emergency medical services | Index Medicus
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11. Full Text Intracerebroventricular administration of galanin antagonist sustains insulin resistance in adipocytes of type 2 diabetic trained rats
by Zhang, Zhenwen and Sheng, Shudong and Guo, Lili and Li, Guangzhi and Zhang, Ling and Zhang, Linxiang and Shi, Mingyi and Bo, Ping and Zhu, Yan
Molecular and cellular endocrinology, ISSN 0303-7207, 09/2012, Volume 361, Issue 1-2, pp. 213 - 218
GLUT4 | Insulin sensitivity | Intracerebroventricular injection | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Bradykinin - analogs & derivatives | Galanin - administration & dosage | Deoxyglucose - metabolism | Glucose Transporter Type 4 - metabolism | Rats, Wistar | Cholesterol - blood | Injections, Intraventricular | Body Weight - drug effects | Male | Peptide Fragments - pharmacology | Adipocytes - drug effects | Insulin - blood | RNA, Messenger - metabolism | Galanin - metabolism | Fasting - blood | Cell Membrane - metabolism | Hypothalamus - drug effects | Bradykinin - pharmacology | Cell Membrane - drug effects | Galanin - antagonists & inhibitors | Physical Conditioning, Animal | Peptide Fragments - administration & dosage | RNA, Messenger - genetics | Insulin Resistance | Rats | Adipocytes - pathology | Galanin - pharmacology | Gene Expression Regulation - drug effects | Diabetes Mellitus, Type 2 - blood | Animals | Hypothalamus - metabolism | Adipocytes - metabolism | Triglycerides - blood | Diabetes Mellitus, Type 2 - pathology | Glucose Clamp Technique | Blood Glucose - metabolism | Bradykinin - administration & dosage | Galanin - genetics | Type 2 diabetes | Neuropeptide Y | Medical colleges | Neuropeptides | Insulin resistance | Diabetes | Glucose | Dextrose | Index Medicus
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