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1. Full Text How Placebos Change the Patient's Brain
by Benedetti, Fabrizio and Carlino, Elisa and Pollo, Antonella
Neuropsychopharmacology, ISSN 0893-133X, 01/2011, Volume 36, Issue 1, pp. 339 - 354
Although placebos have long been considered a nuisance in clinical research, today they represent an active and productive field of research and, because of... 
reward | anxiety | learning | genetics | placebo | nocebo | INFERIOR PREFRONTAL CORTEX | ANTERIOR CINGULATE CORTEX | PSYCHIATRY | CHOLECYSTOKININ ANTAGONIST PROGLUMIDE | STRESS-INDUCED ANALGESIA | NEUROSCIENCES | TRANSIENT ACTIVATION | POSITRON-EMISSION-TOMOGRAPHY | BEHAVIORALLY CONDITIONED IMMUNOSUPPRESSION | PHARMACOLOGY & PHARMACY | ROSTRAL VENTROMEDIAL MEDULLA | CARD SORTING TEST | PARKINSONS-DISEASE | Brain Chemistry - drug effects | Mental Processes - physiology | Affect - drug effects | Neural Pathways - drug effects | Placebo Effect | Affect - physiology | Humans | Parkinson Disease - drug therapy | Cognition - drug effects | Parkinson Disease - physiopathology | Parkinson Disease - psychology | Brain - physiology | Mental Processes - drug effects | Neural Pathways - physiology | Brain Chemistry - physiology | Brain - drug effects | Pain - psychology | Animals | Pain - drug therapy | Pain - physiopathology | Cognition - physiology | Placebos - pharmacology | Pain | Analgesics | Cognition | Movement Disorders | Neuropsychopharmacology Reviews | Neurophysiology
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2. Full Text Modafinil: A Review of Neurochemical Actions and Effects on Cognition
by Minzenberg, Michael J and Carter, Cameron S
Neuropsychopharmacology, ISSN 0893-133X, 06/2008, Volume 33, Issue 7, pp. 1477 - 1502
Modafinil (2-[(Diphenylmethyl)sulfinyl] acetamide, Provigil) is an FDA-approved medication with wake-promoting properties. Pre-clinical studies of modafinil... 
Cognition | Norepinephrine | Dopamine | Modafinil | Psychiatry | norepinephrine | DORSOLATERAL PREFRONTAL CORTEX | STEADY-STATE PHARMACOKINETICS | cognition | DELAYED-RESPONSE TASK | PROMOTING DRUG MODAFINIL | modafinil | DEFICIT HYPERACTIVITY DISORDER | psychiatry | NEUROSCIENCES | ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | HEALTHY MALE-VOLUNTEERS | PHARMACOLOGY & PHARMACY | PLACEBO-CONTROLLED TRIAL | LOCUS-COERULEUS NEURONS | dopamine | FILM-COATED TABLETS | Brain Chemistry - drug effects | Animals | Neuroprotective Agents - pharmacology | Mental Disorders - drug therapy | Humans | Benzhydryl Compounds - pharmacology | Cognition - drug effects
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3. Full Text Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients
by Harris, Richard E and Napadow, Vitaly and Huggins, John P and Pauer, Lynne and Kim, Jieun and Hampson, Johnson and Sundgren, Pia C and Foerster, Bradley and Petrou, Myria and Schmidt-Wilcke, Tobias and Clauw, Daniel J and Lund University and Diagnostisk radiologi, Lund and Lunds universitet and Diagnostic Radiology, (Lund)
Anesthesiology, ISSN 0003-3022, 2013, Volume 119, Issue 6, pp. 1453 - 1464
Background: Chronic pain remains a significant challenge for modern health care as its pathologic mechanisms are largely unknown and preclinical animal models... 
NEUROPATHIC PAIN | INHIBITION | GLUTAMATE RELEASE | FIBROMYALGIA | ROBUST | ANESTHESIOLOGY | PLACEBO-CONTROLLED TRIAL | REGISTRATION | GABAPENTIN | FMRI | PLASTICITY | Brain Chemistry - drug effects | Analgesics - therapeutic use | Chronic Pain - drug therapy | Neural Pathways - drug effects | Double-Blind Method | Humans | Middle Aged | Glutamic Acid - physiology | Pregabalin | Cross-Over Studies | Young Adult | Magnetic Resonance Imaging | Fibromyalgia - drug therapy | Adolescent | Adult | Female | Aged | gamma-Aminobutyric Acid - therapeutic use | Chronic Pain - physiopathology | Pain Measurement | gamma-Aminobutyric Acid - analogs & derivatives | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Anestesi och intensivvård | Anesthesiology and Intensive Care
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4. Full Text Randomized trial of verubecestat for mild-to-moderate Alzheimer's disease
by Egan, Michael F and Kost, James and Tariot, Pierre N and Aisen, Paul S and Cummings, Jeffrey L and Vellas, Bruno and Sur, Cyrille and Mukai, Yuki and Voss, Tiffini and Furtek, Christine and Mahoney, Erin and Mozley, Lyn Harper and Vandenberghe, Rik and Mo, Yi and Michelson, David
New England Journal of Medicine, ISSN 0028-4793, 2018, Volume 378, Issue 18, pp. 1691 - 1703
BACKGROUND Alzheimer's disease is characterized by the deposition of amyloid-beta (A beta) plaques in the brain. A beta is produced from the sequential... 
MEDICINE, GENERAL & INTERNAL | DEMENTIA | INVENTORY | SOLANEZUMAB | CLINICAL-TRIALS | VOLUME | BETA IMMUNIZATION AN1792 | BAPINEUZUMAB | OUTCOMES | RATING-SCALE | Brain Chemistry - drug effects | Double-Blind Method | Aspartic Acid Endopeptidases - antagonists & inhibitors | Humans | Middle Aged | Alzheimer Disease - drug therapy | Male | Thiadiazines - adverse effects | Cognition - drug effects | Thiadiazines - therapeutic use | Activities of Daily Living | Dose-Response Relationship, Drug | Neuropsychological Tests | Cyclic S-Oxides - therapeutic use | Treatment Failure | Aged, 80 and over | Amyloid beta-Peptides - analysis | Amyloid beta-Peptides - cerebrospinal fluid | Female | Aged | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Biomarkers - cerebrospinal fluid | Alzheimer Disease - psychology | Cyclic S-Oxides - adverse effects | Drugs | Treatment outcome | Usage | Care and treatment | Alzheimer's disease | Analysis
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5. Full Text New approaches to antidepressant drug discovery: beyond monoamines
by Berton, Olivier and Nestler, Eric J
Nature Reviews Neuroscience, ISSN 1471-003X, 02/2006, Volume 7, Issue 2, pp. 137 - 151
All available antidepressant medications are based on serendipitous discoveries of the clinical efficacy of two classes of antidepressants more than 50 years... 
CORTICOTROPIN-RELEASING-FACTOR | RECEPTOR ANTAGONISTS | MOOD DISORDERS | NEUROTROPHIC FACTOR | STRESS-RESPONSE | MAJOR DEPRESSION | ANXIETY DISORDERS | SUBSTANCE-P | HORMONE-RECEPTOR | NEUROSCIENCES | NUCLEUS-ACCUMBENS | Brain Chemistry - drug effects | Hypothalamo-Hypophyseal System - drug effects | Antidepressive Agents - classification | Humans | Depressive Disorder - drug therapy | Depressive Disorder - metabolism | Biogenic Monoamines | Hypothalamo-Hypophyseal System - metabolism | Antidepressive Agents - therapeutic use | Animals | Antidepressive Agents - pharmacology | Models, Neurological | Disease Models, Animal
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6. Full Text Methylphenidate Preferentially Increases Catecholamine Neurotransmission within the Prefrontal Cortex at Low Doses that Enhance Cognitive Function
by Berridge, Craig W and Devilbiss, David M and Andrzejewski, Matthew E and Arnsten, Amy F.T and Kelley, Ann E and Schmeichel, Brooke and Hamilton, Christina and Spencer, Robert C
Biological Psychiatry, ISSN 0006-3223, 2006, Volume 60, Issue 10, pp. 1111 - 1120
Low doses of psychostimulants, such as methylphenidate (MPH), are widely used in the treatment of attention-deficit/hyperactivity disorder (ADHD). Surprisingly... 
norepinephrine | ADHD | attention | working memory | dopamine | Psychostimulants | ORAL METHYLPHENIDATE | SUBSTANCE-ABUSE | psychostimulants | RAT | EXTRACELLULAR NOREPINEPHRINE | PSYCHIATRY | DEFICIT HYPERACTIVITY DISORDER | NEUROSCIENCES | ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | FRONTAL LESIONS | SPATIAL WORKING-MEMORY | BASAL FOREBRAIN | Brain Chemistry - drug effects | Chromatography, High Pressure Liquid - methods | Microdialysis - methods | Catecholamines - metabolism | Signal Detection, Psychological - drug effects | Motor Activity - drug effects | Male | Vision, Ocular - drug effects | Behavior, Animal | Dose-Response Relationship, Drug | Prefrontal Cortex - drug effects | Adrenergic Uptake Inhibitors - blood | Drug Administration Routes | Rats | Memory, Short-Term - drug effects | Methylphenidate - pharmacology | Cognition - drug effects | Electroencephalography - methods | Rats, Sprague-Dawley | Sleep - drug effects | Animals | Analysis of Variance | Adrenergic Uptake Inhibitors - pharmacology | Electromyography - methods | Methylphenidate - blood | Catecholamines | Dosage and administration | Methylphenidate hydrochloride | Methylphenidate | Attention-deficit hyperactivity disorder
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