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1. Full Text CODA: Integrating multi-level context-oriented directed associations for analysis of drug effects
by Yu, Hasun and Jung, Jinmyung and Yoon, Seyeol and Kwon, Mijin and Bae, Sunghwa and Yim, Soorin and Lee, Jaehyun and Kim, Seunghyun and Kang, Yeeok and Lee, Dohoen
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 7519 - 12
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Hematologic Diseases - pathology | Liver - pathology | Metabolic Diseases - pathology | Respiratory Tract Diseases - metabolism | Kidney - pathology | Skin - metabolism | Hematologic Diseases - metabolism | Humans | Muscle, Skeletal - metabolism | Respiratory Tract Diseases - drug therapy | Respiratory Tract Diseases - genetics | Brain - metabolism | Musculoskeletal Diseases - pathology | Kidney - metabolism | Liver - drug effects | Muscle, Skeletal - drug effects | Myocardium - metabolism | Nervous System Diseases - metabolism | Nutrition Disorders - pathology | Computational Biology - methods | Kidney - drug effects | Liver - metabolism | Nervous System Diseases - drug therapy | Connective Tissue Diseases - metabolism | Neoplasms - drug therapy | Brain - drug effects | Connective Tissue Diseases - drug therapy | Connective Tissue Diseases - pathology | Lung - drug effects | Brain - pathology | Hematologic Diseases - genetics | Prescription Drugs - pharmacokinetics | Digestive System Diseases - pathology | Neoplasms - metabolism | Cardiovascular Diseases - drug therapy | Drugs, Investigational - pharmacokinetics | Respiratory Tract Diseases - pathology | Hematologic Diseases - drug therapy | Metabolic Diseases - drug therapy | Cardiovascular Diseases - pathology | Nervous System Diseases - genetics | Cardiovascular Diseases - genetics | Musculoskeletal Diseases - genetics | Neoplasms - genetics | Lung - metabolism | Skin - pathology | Nervous System Diseases - pathology | Lung - pathology | Musculoskeletal Diseases - drug therapy | Cardiovascular Diseases - metabolism | Musculoskeletal Diseases - metabolism | Nutrition Disorders - drug therapy | Nutrition Disorders - genetics | Myocardium - pathology | Organ Specificity | Digestive System Diseases - genetics | Algorithms | Digestive System Diseases - drug therapy | Nutrition Disorders - metabolism | Metabolic Diseases - metabolism | Digestive System Diseases - metabolism | Metabolic Diseases - genetics | Connective Tissue Diseases - genetics | Muscle, Skeletal - pathology | Neoplasms - pathology | Skin - drug effects | Drug development | Index Medicus
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2. Full Text Exosomes as drug delivery vehicles for Parkinson's disease therapy
by Haney, Matthew J and Klyachko, Natalia L and Zhao, Yuling and Gupta, Richa and Plotnikova, Evgeniya G and He, Zhijian and Patel, Tejash and Piroyan, Aleksandr and Sokolsky, Marina and Kabanov, Alexander V and Batrakova, Elena V
Journal of controlled release, ISSN 0168-3659, 06/2015, Volume 207, pp. 18 - 30
Oxidative stress | Neuroinflammation | Parkinson's disease | Catalase | Exosomes | Blood–brain barrier | Blood-brain barrier | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Antioxidants - chemistry | Antioxidants - metabolism | Oxidopamine | Anti-Inflammatory Agents - metabolism | PC12 Cells | Neuroprotective Agents - metabolism | Drug Carriers | Brain - metabolism | Nanoparticles | Parkinsonian Disorders - metabolism | Parkinsonian Disorders - drug therapy | Antiparkinson Agents - chemistry | Anti-Inflammatory Agents - administration & dosage | Female | Neurons - metabolism | Neuroprotective Agents - administration & dosage | Nanomedicine | Disease Models, Animal | Neuroprotective Agents - chemistry | Mice, Inbred C57BL | Solubility | Rats | Technology, Pharmaceutical - methods | Parkinsonian Disorders - chemically induced | Administration, Intranasal | Chemistry, Pharmaceutical | Brain - drug effects | Catalase - metabolism | Catalase - administration & dosage | Animals | Anti-Inflammatory Agents - chemistry | Antioxidants - administration & dosage | RAW 264.7 Cells | Antiparkinson Agents - administration & dosage | Mice | Kinetics | Oxidative Stress - drug effects | Antiparkinson Agents - metabolism | Catalase - chemistry | Drugs | Drug delivery systems | Proteases | Analysis | Antiparkinsonian agents | Vehicles | Index Medicus | blood-brain barrier | neuroinflammation | exosomes | catalase | oxidative stress | Parkinson’s disease
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3. The thirteenth step
: addiction in the age of brain science
by Heilig, Markus
2015, ISBN 9780231172363, ix, 303
Brain | Pharmacogenetics | physiopathology | Treatment | Alcoholism | therapy | Behavior, Addictive | drug effects | Substance-Related Disorders | Substance abuse | metabolism | Substance abuse--Treatment | Neurosciences | Brain--Effect of drugs on | Substance abuse--Physiological aspects | Behavior, Addictive - metabolism | Drug addicts
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4. Full Text Potential therapeutic uses of BDNF in neurological and psychiatric disorders
by Nagahara, Alan H and Tuszynski, Mark H
Nature reviews. Drug discovery, ISSN 1474-1776, 03/2011, Volume 10, Issue 3, pp. 209 - 219
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Brain-Derived Neurotrophic Factor - genetics | Genetic Therapy | Epigenomics | Spinal Cord Injuries - drug therapy | Humans | Nervous System Diseases - drug therapy | Alzheimer Disease - drug therapy | Metabolic Diseases - drug therapy | Parkinson Disease - drug therapy | Stroke - drug therapy | Amyotrophic Lateral Sclerosis - drug therapy | Brain-Derived Neurotrophic Factor - administration & dosage | Animals | Brain-Derived Neurotrophic Factor - physiology | Mental Disorders - drug therapy | Cognition - physiology | Adult | Brain-Derived Neurotrophic Factor - therapeutic use | Huntington Disease - drug therapy | Physiological aspects | Care and treatment | Cell receptors | Brain-derived neurotrophic factor | Research | Mental illness | Index Medicus
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5. Full Text Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice
by McLoughlin, Hayley S and Moore, Lauren R and Chopra, Ravi and Komlo, Robert and McKenzie, Megan and Blumenstein, Kate G and Zhao, Hien and Kordasiewicz, Holly B and Shakkottai, Vikram G and Paulson, Henry L
Annals of neurology, ISSN 0364-5134, 07/2018, Volume 84, Issue 1, pp. 64 - 77
Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Action Potentials - genetics | Age Factors | Apoptosis - drug effects | Motor Activity - drug effects | Apoptosis - genetics | Male | Brain - metabolism | Oligonucleotides, Antisense - therapeutic use | Exploratory Behavior - drug effects | Ataxin-3 - chemistry | Female | Microfilament Proteins - metabolism | Purkinje Cells - drug effects | Action Potentials - drug effects | Gliosis - etiology | Disease Models, Animal | Machado-Joseph Disease - pathology | Calcium-Binding Proteins - metabolism | Gene Expression Regulation - genetics | Mice, Transgenic | Mutation - genetics | Brain - drug effects | Gene Expression Regulation - drug effects | Machado-Joseph Disease - drug therapy | Motor Activity - genetics | Animals | Machado-Joseph Disease - physiopathology | Gliosis - drug therapy | Mice | Purkinje Cells - pathology | RNA-Binding Proteins - metabolism | Ataxin-3 - genetics | Machado-Joseph Disease - genetics | Medical research | Therapy | Afterhyperpolarization | Medical treatment | Transgenic mice | Clinical trials | Firing rate | Trinucleotide repeats | Motors | Antisense oligonucleotides | Polyglutamine diseases | Motor task performance | Hereditary diseases | Machado-Joseph disease | Ataxia | Biocompatibility | In vivo methods and tests | Trinucleotide repeat diseases
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6. Full Text The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection
by Vamos, Eniko and Pardutz, Arpad and Klivenyi, Peter and Toldi, Jozsef and Vecsei, Laszlo
Journal of the neurological sciences, ISSN 0022-510X, 2009, Volume 283, Issue 1, pp. 21 - 27
Neurology | Neurological disorders | Central nervous system | Kynurenine pathway | Infectious diseases | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Receptors, Glutamate - metabolism | Brain Diseases - metabolism | Kynurenine - therapeutic use | Humans | Brain Ischemia - metabolism | Epilepsy - metabolism | Parkinson Disease - drug therapy | Neurodegenerative Diseases - drug therapy | Pain - metabolism | Migraine Disorders - metabolism | Brain - metabolism | Brain Diseases - drug therapy | Pain - drug therapy | Parkinson Disease - metabolism | Kynurenine - metabolism | Huntington Disease - drug therapy | Multiple Sclerosis - metabolism | Signal Transduction | Alzheimer Disease - drug therapy | Neurodegenerative Diseases - metabolism | Huntington Disease - metabolism | Migraine Disorders - drug therapy | Animals | Brain Ischemia - drug therapy | Alzheimer Disease - metabolism | Epilepsy - drug therapy | Multiple Sclerosis - drug therapy | Phosphates | Methyl aspartate | Nervous system diseases | Neurosciences | Parkinson's disease | Huntington's chorea | Tryptophan | HIV (Viruses) | Health aspects | Alzheimer's disease | Index Medicus
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