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by Williams, Frances M. K and Carter, Angela M and Hysi, Pirro G and Surdulescu, Gabriela and Hodgkiss, Dylan and Soranzo, Nicole and Traylor, Matthew and Bevan, Steve and Dichgans, Martin and Rothwell, Peter M. W and Sudlow, Cathie and Farrall, Martin and Silander, Kaisa and Kaunisto, Mari and Wagner, Peter and Saarela, Olli and Kuulasmaa, Kari and Virtamo, Jarmo and Salomaa, Veikko and Amouyel, Philippe and Arveiler, Dominique and Ferrieres, Jean and Wiklund, Per-Gunnar and Arfan Ikram, M and Hofman, Albert and Boncoraglio, Giorgio B and Parati, Eugenio A and Helgadottir, Anna and Gretarsdottir, Solveig and Thorsteinsdottir, Unnur and Thorleifsson, Gudmar and Stefansson, Kari and Seshadri, Sudha and DeStefano, Anita and Gschwendtner, Andreas and Psaty, Bruce and Longstreth, Will and Mitchell, Braxton D and Cheng, Yu-Ching and Clarke, Robert and Ferrario, Marco and Bis, Joshua C and Levi, Christopher and Attia, John and Holliday, Elizabeth G and Scott, Rodney J and Fornage, Myriam and Sharma, Pankaj and Furie, Karen L and Rosand, Jonathan and Nalls, Mike and Meschia, James and Mosely, Thomas H and Evans, Alun and Palotie, Aarno and Markus, Hugh S and Grant, Peter J and Spector, Tim D and on Behalf of the EuroCLOT Investigators the Wellcome Trust Case Control Consortium 2 MOnica Risk, Genetics, Archiving and Monograph MetaStroke and the International Stroke Genetics Consortium and EuroCLOT Investigators and Wellcome Trust Case Control Consor and Int Stroke Genetics Consortium and MOnica Risk, Genetics, Archiving and Monograph and MetaStroke and International Stroke Genetics Consortium and Wellcome Trust Case Control Consortium 2
Annals of neurology, ISSN 0364-5134, 2013, Volume 73, Issue 1, pp. 16 - 31
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 43, pp. E4098 - E4107
Journal Article
Neurobiology of disease, ISSN 0969-9961, 2010, Volume 38, Issue 1, pp. 17 - 26
Journal Article
Journal Article
Circulation (New York, N.Y.), ISSN 0009-7322, 03/2012, Volume 125, Issue 9, pp. 1134 - 1146
.... Methods and Results-Rheb is inactivated during cardiomyocyte (CM) glucose deprivation (GD) in vitro, and during acute myocardial ischemia in vivo... 
apoptosis | signal transduction | obesity | ischemia | MAMMALIAN TARGET | RAPAMYCIN | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | MTOR | SKELETAL-MUSCLE | INFARCTION | IMPACT | PATHWAY | INSULIN-RESISTANCE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Myocardial Ischemia - metabolism | TOR Serine-Threonine Kinases - metabolism | Metabolic Syndrome - metabolism | Ras Homolog Enriched in Brain Protein | Autophagy - physiology | TOR Serine-Threonine Kinases - genetics | Dietary Fats - pharmacology | Metabolic Syndrome - physiopathology | Apoptosis Regulatory Proteins - genetics | Myocardial Ischemia - physiopathology | Neuropeptides - genetics | Energy Metabolism - physiology | Cell Survival - physiology | Beclin-1 | Myocytes, Cardiac - cytology | Cells, Cultured | Rats | Neuropeptides - metabolism | Obesity - physiopathology | Glucose - pharmacology | Monomeric GTP-Binding Proteins - genetics | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Myocardial Ischemia - pathology | Obesity - metabolism | Obesity - pathology | Animals | Myocytes, Cardiac - drug effects | Monomeric GTP-Binding Proteins - metabolism | Myocytes, Cardiac - physiology | Signal Transduction - physiology | Mice | Metabolic Syndrome - pathology | Endoplasmic Reticulum Stress - physiology | Physiological aspects | Autophagy (Cytology) | Obesity | Myocardial ischemia | Research | Metabolic syndrome X | myocardial ischemia | autophagy | Rheb | mTORC1
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 7/2011, Volume 108, Issue 28, pp. 11662 - 11667
It is increasingly recognized that the mechanisms underlying ischemic cell death are sexually dimorphic. Stroke-induced cell death in males is initiated by the... 
Messenger RNA | MicroRNA | Ischemia | Cell death | Sex linked differences | Brain ischemia | Strokes | Gene expression regulation | Female animals | Apoptosis | Second mitochondria-derived activator of caspases/direct inhibitor of apoptosis binding protein with low Pi | Spectrin cleavage | Ovariectomy | Middle cerebral artery occlusion | Estrogen | estrogen | OXIDATIVE STRESS | BRAIN-INJURY | spectrin cleavage | MULTIDISCIPLINARY SCIENCES | EXPERIMENTAL STROKE | NEUROPROTECTION | CELL-DEATH | HYPOXIA-ISCHEMIA | IN-VIVO | GENDER | MICE | MICRORNA EXPRESSION | middle cerebral artery occlusion | ovariectomy | second mitochondria-derived activator of caspases/direct inhibitor of apoptosis binding protein with low Pi | Brain Ischemia - genetics | Caspase 3 - metabolism | Brain Ischemia - metabolism | Male | MicroRNAs - metabolism | Mitochondrial Proteins - genetics | RNA, Messenger - metabolism | Brain - metabolism | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | Mitochondrial Proteins - metabolism | Base Sequence | Female | 3' Untranslated Regions | Mice, Inbred C57BL | RNA, Messenger - genetics | Estradiol - administration & dosage | Binding Sites - genetics | Sex Characteristics | X-Linked Inhibitor of Apoptosis Protein - genetics | Benzoquinones - pharmacology | Brain - drug effects | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Brain Ischemia - pathology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Brain - pathology | Mice | MicroRNAs - genetics | Models, Neurological | Physiological aspects | Cerebral ischemia | Genetic aspects | Health aspects | Biological Sciences | direct inhibitor of apoptosis binding protein with low Pi | second mitochondria-derived activator of caspases
Journal Article
Cardiovascular research, ISSN 0008-6363, 09/2012, Volume 95, Issue 4, pp. 487 - 494
...(s) of ischaemia and reperfusion in tissues remote from the heart reduce myocardial ischaemia/reperfusion injury... 
Brain | Vagus nerve | Ischaemia/reperfusion injury | Preconditioning | Ischaemia | CARDIAC & CARDIOVASCULAR SYSTEMS | K-ATP CHANNELS | LIMB ISCHEMIA | MYOCARDIAL-ISCHEMIA | BRAIN-STEM | reperfusion injury | LENTIVIRAL VECTORS | CARDIOVASCULAR CONTROL | TRANSGENE EXPRESSION | RAT-HEART | AUTONOMIC NERVOUS-SYSTEM | Myocardial Infarction - genetics | Hindlimb | Receptors, G-Protein-Coupled - metabolism | Brain Stem - metabolism | Vagus Nerve - drug effects | Male | Receptors, Neuropeptide - metabolism | Drosophila Proteins - metabolism | Rhodopsin - metabolism | Recombinant Fusion Proteins - metabolism | Autonomic Fibers, Preganglionic - metabolism | Brain Stem - drug effects | Action Potentials | Myocardial Reperfusion Injury - pathology | Time Factors | Muscarinic Antagonists - pharmacology | Myocardial Infarction - pathology | Neuropeptides - pharmacology | Adenoviridae - genetics | Lentivirus - genetics | Myocardial Infarction - physiopathology | Neural Pathways - physiopathology | Myocardial Reperfusion Injury - genetics | Autonomic Fibers, Preganglionic - drug effects | Disease Models, Animal | Heart - innervation | Muscle, Skeletal - blood supply | Transduction, Genetic | Vagus Nerve - metabolism | Constriction | Rats | Receptors, Neuropeptide - genetics | Atropine - pharmacology | Myocardium - pathology | Myocardial Infarction - metabolism | Rats, Sprague-Dawley | Myocardial Reperfusion Injury - physiopathology | Vagus Nerve - physiopathology | Myocardial Reperfusion Injury - metabolism | Animals | Rhodopsin - genetics | Ischemic Preconditioning, Myocardial - methods | Brain Stem - physiopathology | Myocardial Infarction - prevention & control | Receptors, G-Protein-Coupled - genetics | Drosophila Proteins - genetics | Genetic Vectors | Myocardial Reperfusion Injury - prevention & control | Original
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 12/2011, Volume 108, Issue 51, pp. 20772 - 20777
Journal Article
Circulation research, ISSN 1524-4571, 2017, Volume 120, Issue 3, pp. 472 - 495
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