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Annals of neurology, ISSN 0364-5134, 2013, Volume 74, Issue 3, pp. 458 - 471
Journal Article
Stem cells translational medicine, ISSN 2157-6580, 2016, Volume 5, Issue 6, pp. 754 - 763
...) in a preclinical model of preterm hypoxic-ischemic brain injury. Ovine fetuses were subjected to global hypoxia-ischemia by transient umbilical cord occlusion, followed by in utero intravenous administration of MSC-EVs... 
Inflammation/physiopathology | Cell Proliferation | Humans | Cell- and Tissue-Based Therapy | Brain/physiopathology | Extracellular Vesicles/metabolism | Mesenchymal Stem Cells/cytology | Journal Article | Cell Biology | Animals | Hypoxia-Ischemia, Brain/physiopathology | Research Support, Non-U.S. Gov't | Fetus | Sheep | Brain Injuries/physiopathology | Developmental Biology | Disease Models, Animal | Extracellular vesicles | Mesenchymal stromal cells | Exosomes | Brain injury | Hypoxia-ischemia | Preterm | FUNCTIONAL RECOVERY | STEM-CELLS | MYOCARDIAL-INFARCTION | ANGIOGENESIS | CEREBRAL INFLAMMATION | INJURY | SHEEP | NEUROVASCULAR PLASTICITY | CELL & TISSUE ENGINEERING | THERAPY | Brain - physiopathology | Mesenchymal Stromal Cells - metabolism | Brain Injuries - therapy | Brain Injuries - physiopathology | Extracellular Vesicles - metabolism | Inflammation - therapy | Mesenchymal Stromal Cells - cytology | Hypoxia-Ischemia, Brain - therapy | Hypoxia-Ischemia, Brain - physiopathology | Inflammation - physiopathology | Traumatic brain injury | Mesenchyme | Fetuses | Electroencephalography | Catheters | Heart rate | Vesicles | Ischemia | Polyethylene glycol | Bone marrow | Hypoxia | Blood pressure | Umbilical cord | Age | Seizures | Cell-Based Drug Development, Screening, and Toxicology
Journal Article
Circulation, ISSN 0009-7322, 03/2012, Volume 125, Issue 9, pp. 1134 - 1146
.... Methods and Results-Rheb is inactivated during cardiomyocyte (CM) glucose deprivation (GD) in vitro, and during acute myocardial ischemia in vivo... 
apoptosis | signal transduction | obesity | ischemia | MAMMALIAN TARGET | RAPAMYCIN | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | MTOR | SKELETAL-MUSCLE | INFARCTION | IMPACT | PATHWAY | INSULIN-RESISTANCE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Myocardial Ischemia - metabolism | TOR Serine-Threonine Kinases - metabolism | Metabolic Syndrome - metabolism | Ras Homolog Enriched in Brain Protein | Autophagy - physiology | TOR Serine-Threonine Kinases - genetics | Dietary Fats - pharmacology | Metabolic Syndrome - physiopathology | Apoptosis Regulatory Proteins - genetics | Myocardial Ischemia - physiopathology | Neuropeptides - genetics | Energy Metabolism - physiology | Cell Survival - physiology | Beclin-1 | Myocytes, Cardiac - cytology | Cells, Cultured | Rats | Neuropeptides - metabolism | Obesity - physiopathology | Glucose - pharmacology | Monomeric GTP-Binding Proteins - genetics | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Myocardial Ischemia - pathology | Obesity - metabolism | Obesity - pathology | Animals | Myocytes, Cardiac - drug effects | Monomeric GTP-Binding Proteins - metabolism | Myocytes, Cardiac - physiology | Signal Transduction - physiology | Mice | Metabolic Syndrome - pathology | Endoplasmic Reticulum Stress - physiology | Physiological aspects | Autophagy (Cytology) | Obesity | Myocardial ischemia | Research | Metabolic syndrome X | myocardial ischemia | autophagy | Rheb | mTORC1
Journal Article
Neuroscience, ISSN 0306-4522, 2009, Volume 158, Issue 3, pp. 983 - 994
Journal Article