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Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, pp. 8760 - 8760
Circulating tumour DNA analysis can be used to track tumour burden and analyse cancer genomes non-invasively but the extent to which it represents metastatic... 
HETEROGENEITY | ACTIVATION | VARIANTS | PATHWAY | MULTIDISCIPLINARY SCIENCES | KINASE | ACQUIRED-RESISTANCE | SEQUENCING DATA | Carcinoma, Ductal, Breast - genetics | Receptors, Estrogen - metabolism | Humans | Receptor, ErbB-2 - metabolism | Clonal Evolution - genetics | Tamoxifen - administration & dosage | Case-Control Studies | Breast Neoplasms - metabolism | Brain Neoplasms - secondary | Carcinoma, Ductal, Breast - drug therapy | Neoplasm Metastasis | Lung Neoplasms - secondary | Adult | Carcinoma, Ductal, Breast - pathology | Female | Quinazolines - administration & dosage | Liver Neoplasms - secondary | Carcinoma, Ductal, Breast - metabolism | Lung Neoplasms - genetics | Liver Neoplasms - genetics | Deoxycytidine - administration & dosage | Brain Neoplasms - genetics | Trastuzumab - administration & dosage | Breast Neoplasms - drug therapy | Sequence Analysis, DNA | Spinal Neoplasms - secondary | Breast Neoplasms - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Spinal Neoplasms - genetics | Bayes Theorem | DNA, Neoplasm - genetics | Mutation | Deoxycytidine - analogs & derivatives | Biological evolution | Breast cancer | Genomes | Metastasis | ErbB-2 protein | Patients | Metastases | Heterogeneity | Biopsy | Breast | Evolution | Deoxyribonucleic acid--DNA | Cancer | Tumors | Index Medicus
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 03/2013, Volume 8, Issue 3, pp. 346 - 351
Journal Article
Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, pp. 8839 - 8839
Journal Article
Journal Article
Science, ISSN 0036-8075, 07/2017, Volume 357, Issue 6349, pp. 409 - 413
The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of somatic mutations. In a proof-of-concept study, we previously showed... 
CELL LUNG-CANCER | SURVIVAL | COLORECTAL CARCINOMAS | RECEIVING NIVOLUMAB | IMMUNOTHERAPY | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | NEOANTIGENS | CHECKPOINT BLOCKADE | LYMPHOCYTES | Neoplastic Syndromes, Hereditary - immunology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Neoplastic Syndromes, Hereditary - mortality | Young Adult | Colorectal Neoplasms - therapy | Brain Neoplasms - immunology | DNA Mismatch Repair | Aged, 80 and over | Adult | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Biomarkers, Tumor - antagonists & inhibitors | Colorectal Neoplasms - mortality | Antibodies, Monoclonal, Humanized - therapeutic use | Antigens, Neoplasm - immunology | Brain Neoplasms - genetics | Disease-Free Survival | Colorectal Neoplasms - immunology | Cell Cycle Checkpoints - drug effects | Brain Neoplasms - therapy | Neoplastic Syndromes, Hereditary - therapy | T-Lymphocytes - immunology | Aged | Mutation | Programmed Cell Death 1 Receptor - immunology | Colorectal cancer | Genetic aspects | Nucleotide sequencing | Health aspects | DNA repair | Methods | Tumors | DNA sequencing | Yeast | PD-1 protein | Antibodies | Clinical trials | Genomes | Functional analysis | Lymphocytes T | Patients | Survival | Colon cancer | Immune checkpoint | Immunotherapy | Mismatch repair | Pancreatic cancer | Biomarkers | Bioindicators | Colon | Solid tumors | Genetic recombination | Repair | Cancer | Apoptosis | Index Medicus
Journal Article
Science, ISSN 0036-8075, 3/2013, Volume 339, Issue 6123, pp. 1077 - 1080
Journal Article
Nature, ISSN 0028-0836, 01/2018, Volume 553, Issue 7689, pp. 467 - 472
Chromosomal instability is a hallmark of cancer that results from ongoing errors in chromosome segregation during mitosis. Although chromosomal instability is... 
BREAST-CANCER | MIGRATION | CELLS | ANEUPLOIDY | ACTIVATION | EVOLUTION | PROGNOSIS | PATHWAY | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | EXPRESSION | Breast Neoplasms - secondary | DNA, Neoplasm - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Brain Neoplasms - pathology | NF-kappa B - metabolism | Cytosol - enzymology | Brain Neoplasms - secondary | Inflammation - metabolism | Female | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Cell Line | Micronuclei, Chromosome-Defective | Chromosome Segregation | Brain Neoplasms - genetics | Head and Neck Neoplasms - pathology | Xenograft Model Antitumor Assays | Chromosomal Instability - genetics | Neoplasm Metastasis - genetics | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Inflammation - genetics | Cytosol - metabolism | Head and Neck Neoplasms - genetics | Mesoderm - metabolism | Mice | Complications and side effects | Development and progression | Genetic aspects | Metastasis | Chromosomal instability syndromes | Genetic suppression | Mitosis | Activation | Genomes | Cytosol | Metastases | Genomic instability | Stimulators | Signal transduction | Cyclic GMP | Chromosomes | Deoxyribonucleic acid--DNA | NF-κB protein | Stability | AMP | Organs | Breast cancer | Survival analysis | Signaling | Medical prognosis | Micronuclei | Interferon | Cancer | Tumors | Index Medicus
Journal Article
BMC Cancer, ISSN 1471-2407, 11/2013, Volume 13, Issue 1, pp. 537 - 537
Background: Triple Negative subset of (TN) Breast Cancers (BC), a close associate of the basal-like subtype (with limited discordance) is an aggressive form of... 
Breast cancer | Microarray | Wnt | FFPE | Triple negative | GENE-EXPRESSION SIGNATURE | ANDROGEN RECEPTOR | REGULATES EXPRESSION | SUBTYPES | T-CELL-FACTOR | BETA-CATENIN | MESENCHYMAL TRANSITION | ONCOLOGY | PATHWAY | COLORECTAL-CANCER | BASAL | RNA, Small Interfering - genetics | Cell Proliferation | Prognosis | Follow-Up Studies | Oligonucleotide Array Sequence Analysis | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Bone Neoplasms - secondary | Gene Expression Profiling | Wnt Proteins - metabolism | Brain Neoplasms - metabolism | Immunoenzyme Techniques | Bone Neoplasms - metabolism | Neoplasm Recurrence, Local - pathology | Paraffin Embedding | Brain Neoplasms - secondary | Wnt Proteins - genetics | Lung Neoplasms - secondary | Triple Negative Breast Neoplasms - pathology | Biomarkers, Tumor - metabolism | Female | Bone Neoplasms - genetics | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Lung Neoplasms - genetics | Neoplasm Recurrence, Local - metabolism | Signal Transduction | RNA, Messenger - genetics | Brain Neoplasms - genetics | Survival Rate | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Blotting, Western | beta Catenin - genetics | Triple Negative Breast Neoplasms - genetics | Triple Negative Breast Neoplasms - metabolism | beta Catenin - antagonists & inhibitors | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Neoplasm Staging | Cell Movement | Cohort Studies | Research | Metastasis | Biological markers | Analysis | Oncology, Experimental | Cancer | Index Medicus
Journal Article
Science, ISSN 0036-8075, 2014, Volume 343, Issue 6167, pp. 189 - 193
Journal Article