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Journal Article
The New England journal of medicine, ISSN 1533-4406, 2016, Volume 374, Issue 10, pp. 951 - 958
Journal Article
Cell reports (Cambridge), ISSN 2211-1247, 2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2018, Volume 99, Issue 1, pp. 64 - 82.e7
Investigators have long suspected that pathogenic microbes might contribute to the onset and progression of Alzheimer’s disease (AD) although definitive... 
systems biology | Roseolovirus | integrative genomics | human herpesvirus | multiscale networks | HHV-6B | HHV-7 | HHV-6A | network biology | Alzheimer's disease | AMYLOID PEPTIDE | READ ALIGNMENT | G-QUADRUPLEXES | TRANSFER-RNAS | IN-VIVO | DISEASE | POLY(ADP-RIBOSE) POLYMERASE-1 | EXPRESSION PROFILES | SIMPLEX INFECTION | NEUROSCIENCES | EPSTEIN-BARR-VIRUS | Amyloid Precursor Protein Secretases - genetics | Encephalitis, Viral - genetics | Encephalitis, Viral - virology | Genomics | Humans | Brain - virology | Gene Expression Profiling | Aspartic Acid Endopeptidases - genetics | Gene Regulatory Networks | Herpesvirus 7, Human | Case-Control Studies | Herpesvirus 6, Human | Viral Load | Alzheimer Disease - pathology | Brain - metabolism | Microbiota | Monomeric Clathrin Assembly Proteins - genetics | Tumor Suppressor Proteins - genetics | Amyloid beta-Protein Precursor - metabolism | Encephalitis, Viral - metabolism | Nuclear Proteins - genetics | Roseolovirus Infections - pathology | Clusterin - genetics | Roseolovirus Infections - genetics | Presenilin-1 - genetics | Mice, Transgenic | Roseolovirus Infections - metabolism | Mice, Knockout | Alzheimer Disease - virology | Animals | Adaptor Proteins, Signal Transducing - genetics | Alzheimer Disease - metabolism | Proteomics | Brain - pathology | Roseolovirus Infections - virology | Encephalitis, Viral - pathology | Mice | MicroRNAs - genetics | Alzheimer Disease - genetics | Cohort Studies | Brain | Medical colleges | Medical research | Genetic research | Medicine, Experimental | Development and progression | b-Site APP cleaving enzyme 1 | Neuropathology | Herpes simplex | Viruses | Gene expression | Neuromodulation | Protein turnover | Proteins | Brain research | Neurodegeneration | Autopsy | Data collection
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2016, Volume 388, Issue 10047, pp. 898 - 904
Summary Background Zika virus is an arthropod-borne virus that is a member of the family Flaviviridae transmitted mainly by mosquitoes of the genus Aedes .... 
Internal Medicine | ETIOLOGY | MEDICINE, GENERAL & INTERNAL | STATES | VIRUS-INFECTION | ARTHROGRYPOSIS | UPDATE | TISSUES | BRAIN | PCR | Pregnancy Trimester, Second | Limb Deformities, Congenital - virology | Pregnancy Complications, Infectious - virology | Neuroglia - pathology | Zika Virus Infection - congenital | Humans | Abortion, Spontaneous - virology | Brain - virology | Infant | Male | Microcephaly - virology | Pregnancy Trimester, First | Pregnancy Trimester, Third | Antigens, Viral - isolation & purification | Autopsy | Microcephaly - pathology | Fatal Outcome | Brazil | Adult | Female | RNA, Viral - isolation & purification | Zika Virus - immunology | Zika Virus Infection - pathology | Zika Virus - isolation & purification | Reverse Transcriptase Polymerase Chain Reaction | Pregnancy Complications, Infectious - pathology | Syndrome | Immunohistochemistry - methods | Pregnancy | Ultrasonography, Prenatal | Limb Deformities, Congenital - diagnostic imaging | Placenta - pathology | Brain - pathology | Neuroglia - virology | Placenta - virology | Virus diseases | Mosquitoes | Lung diseases | Birth defects | Conjunctivitis | Health aspects | Hyperthermia | Abortion | Fever | Zoonoses | Diseases | Disease transmission | Genetic disorders | Analysis | Pathology | Zika virus | Congenital diseases | Maternal & child health | Newborn babies | Health risk assessment
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2016, Volume 375, Issue 5, pp. 481 - 484
Journal Article
Journal Article