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Nature cell biology, ISSN 1476-4679, 2013, Volume 15, Issue 7, pp. 807 - 817
Journal Article
BMC cancer, ISSN 1471-2407, 2006, Volume 6, Issue 1, pp. 225 - 225
Background: HER2/neu overexpression is linked to promotion of angiogenesis in breast cancer. We therefore tested the activity of the combination of Trastuzumab... 
PROTEIN | ANGIOGENESIS | ONCOLOGY | NEU ONCOGENE | EPIDERMAL-GROWTH-FACTOR | IN-VIVO | PHASE-II | MONOCLONAL-ANTIBODY | ANTITUMOR-ACTIVITY | FACTOR RECEPTOR | PLUS | Lung Neoplasms - drug therapy | Cyclophosphamide - administration & dosage | Humans | Middle Aged | Neoplasm Proteins - immunology | Bone Neoplasms - secondary | Antibodies, Monoclonal - therapeutic use | Neoplasm Proteins - antagonists & inhibitors | Cyclophosphamide - adverse effects | Bone Neoplasms - blood supply | Leukopenia - chemically induced | Receptor, ErbB-2 - antagonists & inhibitors | Receptor, ErbB-2 - immunology | Liver Neoplasms - secondary | Combined Modality Therapy | Lung Neoplasms - therapy | Lymphatic Metastasis | Breast Neoplasms - blood supply | Brain Neoplasms - drug therapy | Breast Neoplasms - drug therapy | Remission Induction | Methotrexate - adverse effects | Breast Neoplasms - genetics | Brain Neoplasms - therapy | Immunization, Passive | Methotrexate - administration & dosage | Trastuzumab | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Bone Neoplasms - therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Brain Neoplasms - blood supply | Liver Neoplasms - therapy | Ventricular Dysfunction, Left - chemically induced | Breast Neoplasms - therapy | Antibodies, Monoclonal, Humanized | Brain Neoplasms - secondary | Lung Neoplasms - secondary | Angiogenesis Inhibitors - therapeutic use | Adult | Female | Bone Neoplasms - drug therapy | Neutropenia - chemically induced | Lung Neoplasms - blood supply | Drug Administration Schedule | Liver Neoplasms - drug therapy | Treatment Outcome | Gene Amplification | Liver Neoplasms - blood supply | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Genes, erbB-2 | Aged
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 3, p. e91811
Background: We aimed to evaluate the clinical significance of microvessel density (MVD), lymphatic vessel density (LVD), and cancer-associated fibroblasts... 
HETEROGENEITY | SURVIVAL | MULTIDISCIPLINARY SCIENCES | BREAST CARCINOMAS | PTEN | MICROVESSEL DENSITY | STROMA | MUTATIONS | LYMPHATIC VESSEL DENSITY | TUMOR-GROWTH | EXPRESSION | Prognosis | Lung Neoplasms - mortality | Colorectal Neoplasms - genetics | Humans | Middle Aged | Neovascularization, Pathologic | Microvessels - pathology | Male | Ovarian Neoplasms - mortality | Liver Neoplasms - mortality | Actins - genetics | Ovarian Neoplasms - genetics | Lymphatic Vessels - blood supply | Ovarian Neoplasms - secondary | Lung Neoplasms - secondary | Aged, 80 and over | Peritoneal Neoplasms - blood supply | Adult | Female | Ovarian Neoplasms - blood supply | Liver Neoplasms - secondary | Lung Neoplasms - blood supply | Peritoneal Neoplasms - secondary | Colorectal Neoplasms - mortality | Lung Neoplasms - genetics | PTEN Phosphohydrolase - genetics | Colorectal Neoplasms - blood supply | Liver Neoplasms - genetics | Lymphatic Metastasis | Fibroblasts - pathology | Peritoneal Neoplasms - mortality | Liver Neoplasms - blood supply | Peritoneal Neoplasms - genetics | Lymphatic Vessels - pathology | Survival Analysis | Desmin - genetics | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms - pathology | Immunohistochemistry | Cancer patients | Care and treatment | Metastasis | Muscle proteins | Colorectal cancer | Liver | Colorectal carcinoma | Regional analysis | Muscles | Smooth muscle | Patients | Desmin | Lymph nodes | Metastases | Studies | Pathology | Heterogeneity | Lungs | Actin | Rodents | Fibroblasts | Microenvironments | Microvasculature | Mutation | PTEN protein | Cancer | Peritoneum
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 11/2003, Volume 100, Issue 24, pp. 14259 - 14262
Journal Article
Nature communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 2516
Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion... 
INTERSTITIAL FLUID PRESSURE | BREAST-CANCER | GROWTH-FACTOR-BETA | PANCREATIC STELLATE CELLS | TGF-BETA | AORTIC-ANEURYSM | SOLID STRESS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | GENE-EXPRESSION | II TYPE-2 RECEPTOR
Journal Article
Oncogene, ISSN 0950-9232, 01/2012, Volume 31, Issue 3, pp. 293 - 305
Tumor endothelial markers (TEMs) that are highly expressed in human tumor vasculature compared with vasculature in normal tissue hold clear therapeutic... 
cell migration | shear stress | tumor vasculature | gene expression | CELL GENES | SOLID TUMORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAGIC ROUNDABOUT | RECEPTOR | FLOW | CELL BIOLOGY | RESPONSES | THROMBOMODULIN | ONCOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | SURFACE | PROGRESSION | Prostatic Neoplasms - metabolism | Cell Adhesion Molecules - genetics | Humans | Male | Lectins, C-Type - genetics | Breast Neoplasms - metabolism | Lectins, C-Type - metabolism | Biomarkers, Tumor - metabolism | Carcinoma, Hepatocellular - blood supply | Female | Liver Neoplasms - pathology | Ovarian Neoplasms - metabolism | Ovarian Neoplasms - blood supply | Urinary Bladder Neoplasms - metabolism | Prostatic Neoplasms - blood supply | Biomarkers, Tumor - analysis | Zebrafish | Breast Neoplasms - blood supply | Cell Adhesion Molecules - metabolism | Urinary Bladder Neoplasms - blood supply | Animals | Liver Neoplasms - blood supply | Pseudopodia - metabolism | Endothelium, Vascular - metabolism | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Biomarkers, Tumor - genetics | Neovascularization, Pathologic - metabolism | Carcinoma, Hepatocellular - metabolism | Cell Movement | Genetic markers | Growth | Cancer cells | Vascular endothelium | Genetic aspects | Neovascularization | Identification and classification | Immunohistochemistry | Genotype & phenotype | Angiogenesis | Gene expression | Tumors | Cell adhesion & migration | Cell culture | Antibodies | Development | Lectins | Pseudopodia | Antisera | Mechanical stimuli | Solid tumors | Immunofluorescence | Cell migration
Journal Article
PloS one, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155242
.... The immunohistochemical expression of various angiogenic factors in tissues from primary melanomas and metastases as well as their concentration in blood samples were examined... 
BREAST-CANCER | FACTOR VEGF | BIOMARKERS | CELLS | ANGIOGENESIS | NAB-PACLITAXEL | MULTIDISCIPLINARY SCIENCES | HSP27 | RESISTANCE | PLUS BEVACIZUMAB | ENDOTHELIAL GROWTH-FACTOR | Lung Neoplasms - drug therapy | Bevacizumab - therapeutic use | Prognosis | Skin Neoplasms - drug therapy | Melanoma - blood supply | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Vascular Endothelial Growth Factor A - genetics | Neovascularization, Pathologic - pathology | HSP27 Heat-Shock Proteins - genetics | Lung Neoplasms - secondary | Melanoma - genetics | Angiogenesis Inhibitors - therapeutic use | Adult | Female | Skin Neoplasms - blood supply | Liver Neoplasms - secondary | Lung Neoplasms - blood supply | Lung Neoplasms - genetics | Skin Neoplasms - pathology | Liver Neoplasms - genetics | Signal Transduction | Liver Neoplasms - drug therapy | Vascular Endothelial Growth Factor A - blood | Lymphatic Metastasis | Fibroblast Growth Factor 2 - blood | HSP27 Heat-Shock Proteins - blood | Melanoma - secondary | Biomarkers, Tumor - blood | Fibroblast Growth Factor 2 - genetics | Liver Neoplasms - blood supply | Neovascularization, Pathologic - drug therapy | Melanoma - drug therapy | Skin Neoplasms - genetics | Neovascularization, Pathologic - genetics | Biomarkers, Tumor - genetics | Melanoma | Heat shock proteins | Physiological aspects | Development and progression | Genetic aspects | Research | Metastasis | Drug therapy | Fibroblast growth factor | Colorectal cancer | Tissues | Cancer therapies | Density | Blood | Bevacizumab | Metastases | Skin cancer | Angiogenesis | Surgery | Fibroblasts | Bioindicators | Vascular endothelial growth factor | Fibroblast growth factor 2 | Splicing | Breast cancer | Patients | Blood levels | Chemotherapy | Hospitals | Hsp27 protein | Medical prognosis | Biomarkers | Microvasculature | Clinical medicine | Tumors | Heat shock
Journal Article
International journal of radiation oncology, biology, physics, ISSN 0360-3016, 2012, Volume 82, Issue 5, pp. e725 - e731
... were observed, with decreasing tissue blood volume fractions. Introduction Positron emission tomography (PET) is a molecular imaging technique to quantitatively assess... 
Radiology | Hematology, Oncology and Palliative Medicine | Positron-emission tomography | Fluorodeoxyglucose F18 | Patlak analysis | Tissue distribution | Pharmacokinetics | CEREBRAL GLUCOSE-UTILIZATION | BLOOD-FLOW | HYPOXIA | CELL LUNG-CANCER | CHEMOTHERAPY RESPONSE EVALUATION | F-18-FDG PET | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | COLORECTAL-CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Neoplasms - metabolism | Fluorodeoxyglucose F18 - pharmacokinetics | Phosphorylation | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Breast Neoplasms - metabolism | Blood Volume | Adult | Female | Breast Neoplasms - diagnostic imaging | Colorectal Neoplasms - metabolism | Lung Neoplasms - blood supply | Radiopharmaceuticals - pharmacokinetics | Colorectal Neoplasms - blood supply | Carcinoma, Non-Small-Cell Lung - blood supply | Carcinoma, Non-Small-Cell Lung - metabolism | Neoplasms - blood supply | Colorectal Neoplasms - diagnostic imaging | Breast Neoplasms - blood supply | Positron-Emission Tomography - methods | Neoplasms - diagnostic imaging | Glucose - metabolism | Lung Neoplasms - diagnostic imaging | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Glucose metabolism | PET imaging | Analysis | Physiological aspects | Glucose | Dextrose | Tumors | PATIENTS | REACTION KINETICS | NEOPLASMS | PHOSPHORYLATION | FLUORODEOXYGLUCOSE | RADIATION DOSES | SIMULATION | METABOLISM | GLUCOSE | POSITRON COMPUTED TOMOGRAPHY | UPTAKE | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | FLUORINE 18 | BLOOD
Journal Article
Annals of oncology, ISSN 0923-7534, 04/2012, Volume 23, Issue 4, pp. 1030 - 1036
Journal Article