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1. Full Text Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update
by Mao, Qingcheng and Mao, Qingcheng and Unadkat, Jashvant D and Unadkat, Jashvant D
The AAPS journal, ISSN 1550-7416, 1/2015, Volume 17, Issue 1, pp. 65 - 82
Biochemistry, general | BCRP | Biotechnology | Biomedicine | Pharmacy | transporter | ATP-binding cassette | drug transport | Pharmacology/Toxicology | ABCG2 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Breast Neoplasms - drug therapy | Neoplasms - drug therapy | Tissue Distribution | Animals | Biological Transport | Breast Neoplasms - pathology | ATP-Binding Cassette Transporters - metabolism | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Neoplasms - pathology | ATP-Binding Cassette Transporters - antagonists & inhibitors | Drugs | Chemotherapy | Estrogen | Breast cancer | Uric acid | Drug resistance | Sulfates | Cancer | Index Medicus
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2. Full Text Evaluation of the Usefulness of Breast Cancer Resistance Protein (BCRP) Knockout Mice and BCRP Inhibitor-Treated Monkeys to Estimate the Clinical Impact of BCRP Modulation on the Pharmacokinetics of BCRP Substrates
by Karibe, Tsuyoshi and Hagihara-Nakagomi, Rie and Abe, Koji and Imaoka, Tomoki and Mikkaichi, Tsuyoshi and Yasuda, Satoru and Hirouchi, Masakazu and Watanabe, Nobuaki and Okudaira, Noriko and Izumi, Takashi
Pharmaceutical research, ISSN 0724-8741, 05/2015, Volume 32, Issue 5, pp. 1634 - 1647
BCRP | Gastrointestinal absorption | ABCG2 421C>A | Cynomolgus monkey | Knockout mouse | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Quinolines - blood | Area Under Curve | Fatty Acids, Monounsaturated - administration & dosage | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - blood | Intestinal Absorption - drug effects | Macaca fascicularis | Male | Quinolines - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - blood | Rosuvastatin Calcium - administration & dosage | Indoles - administration & dosage | Quinolines - pharmacokinetics | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Sulfasalazine - pharmacokinetics | ATP-Binding Cassette Transporters - genetics | Sulfasalazine - blood | ATP-Binding Cassette Transporters - metabolism | Fatty Acids, Monounsaturated - blood | Female | Rosuvastatin Calcium - blood | Caco-2 Cells | Tetrahydroisoquinolines - pharmacology | Rosuvastatin Calcium - pharmacokinetics | Indoles - blood | Mice, Knockout | Sulfasalazine - administration & dosage | Animals | Acridines - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Fatty Acids, Monounsaturated - pharmacokinetics | Indoles - pharmacokinetics | ATP-Binding Cassette Transporters - antagonists & inhibitors | Sulfasalazine | Breast cancer | Proteins | Pharmacology | Kinetics | Drug resistance | Monkeys & apes | Substrates | Index Medicus
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3. Full Text Structure–activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP)
by Pick, Anne and Müller, Henrik and Mayer, Ralf and Haenisch, Britta and Pajeva, Ilza K and Weigt, Mathias and Bönisch, Heinz and Müller, Christa E and Wiese, Michael
Bioorganic & medicinal chemistry, ISSN 0968-0896, 03/2011, Volume 19, Issue 6, pp. 2090 - 2102
P-glycoprotein | Flavonoids | QSAR | Multidrug resistance | Hoechst 33342 assay | Breast cancer resistance protein | CoMFA | CoMSIA | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | General aspects | Pharmacognosy. Homeopathy. Health food | General pharmacology | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Models, Molecular | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Antineoplastic Agents - chemistry | Neoplasm Proteins - metabolism | Breast Neoplasms - drug therapy | Flavonoids - therapeutic use | Flavonoids - chemical synthesis | Hydrogen Bonding | ATP-Binding Cassette Transporters - metabolism | Cell Line, Tumor | Female | Flavonoids - chemistry | Quantitative Structure-Activity Relationship | ATP-Binding Cassette Transporters - antagonists & inhibitors | Breast cancer | Drug resistance | Analysis | Isoflavones | Index Medicus
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4. Full Text Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
by Doyle, L. Austin and Ross, Douglas D
Oncogene, ISSN 0950-9232, 10/2003, Volume 22, Issue 47, pp. 7340 - 7358
BCRP | Drug resistance | ABC transporter | ABCG2 | Cancer | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Drug Resistance, Multiple | Humans | Gene Expression Regulation, Neoplastic | Substrate Specificity | Drug Resistance, Neoplasm | Neoplasm Proteins - chemistry | Neoplasm Proteins - metabolism | Breast Neoplasms - drug therapy | Breast Neoplasms - metabolism | ATP-Binding Cassette Transporters - chemistry | Animals | Breast Neoplasms - genetics | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Index Medicus
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5. Full Text Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. A role for BCRP in cellular folate homeostasis
by Ifergan, Ilan and Shafran, Assaf and Jansen, Gerrit and Hooijberg, Jan Henik and Scheffer, George L and Assaraf, Yehuda G
The Journal of biological chemistry, ISSN 0021-9258, 06/2004, Volume 279, Issue 24, pp. 25527 - 34
Immunohistochemistry | ATP Binding Cassette Transporter, Subfamily G, Member 2 | Peptide Synthases/metabolism | ATP-Binding Cassette Transporters/analysis | Humans | Folic Acid/metabolism | Homeostasis | Multidrug Resistance-Associated Proteins/physiology | Reverse Transcriptase Polymerase Chain Reaction | Membrane Transport Proteins/physiology | Flow Cytometry | Cell Line, Tumor | Female | Neoplasm Proteins/analysis | Breast Neoplasms/drug therapy | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neoplasm Proteins - physiology | ATP-Binding Cassette Transporters - physiology | Breast Neoplasms - drug therapy | Membrane Transport Proteins - physiology | ATP-Binding Cassette Transporters - analysis | Breast Neoplasms - metabolism | Peptide Synthases - metabolism | ATP-Binding Cassette Transporters - genetics | Multidrug Resistance-Associated Proteins - physiology | Folic Acid - metabolism | Neoplasm Proteins - analysis | Neoplasm Proteins - genetics | Index Medicus
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6. Full Text Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
by Natarajan, Karthika and Xie, Yi and Baer, Maria R and Ross, Douglas D
Biochemical pharmacology, ISSN 0006-2952, 04/2012, Volume 83, Issue 8, pp. 1084 - 1103
ATP binding cassette transporters | Drug absorption, distribution, metabolism and excretion | Drug resistance | Breast cancer resistance protein | ABCG2 | Cancer | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Neoplasms - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 2 | Cell Hypoxia - drug effects | Drug Resistance, Multiple | Humans | Neoplasm Proteins - physiology | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | ATP-Binding Cassette Transporters - physiology | Blood-Brain Barrier - drug effects | Neoplasms - drug therapy | Female | Antineoplastic Agents - pharmacology | Neoplasms - pathology | ATP-Binding Cassette Transporters - antagonists & inhibitors | Antimitotic agents | Medical colleges | Care and treatment | Breast cancer | Drug therapy | Antineoplastic agents | Protein binding | Index Medicus | cancer | drug resistance | drug absorption, distribution, metabolism and excretion | Breast Cancer Resistance Protein
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