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Angewandte Chemie (International ed.), ISSN 1433-7851, 2018, Volume 57, Issue 27, pp. 8332 - 8332
Breslow intermediates are the mechanistic heart of thiamine catalysis in vitamin... 
Breslow intermediates | carbenes | reaction mechanisms | NMR spectroscopy | umpolung
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 05/2017, Volume 56, Issue 22, pp. 6321 - 6323
Journal Article
Angewandte Chemie, ISSN 0044-8249, 01/2016, Volume 128, Issue 1, pp. 363 - 366
Breslow intermediates that bear radical‐stabilizing N substituents, such as benzyl, cinnamyl, and diarylmethyl, undergo facile homolytic C... 
Radikale | Umlagerungen | Breslow‐Intermediate | N‐Heterocyclische Carbene | Thiamin | Enzymes | Analysis | Computation | Condensates | Bonding | Scission | Benzoin | Radicals
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 01/2019, Volume 141, Issue 2, pp. 1109 - 1117
Journal Article
Angewandte Chemie, ISSN 1521-3757, 2018, Volume 130, Issue 27, pp. 8464 - 8464
Breslow‐Intermediate …… haben zentrale mechanistische Bedeutung für die Thiamin‐Katalyse in Vitamin‐B1‐abhängigen Enzymen wie der Pyruvat... 
Breslow-Intermediate | Carbene | Umpolungsreaktionen | NMR-Spektroskopie | Reaktionsmechanismus | Thiamine | Nuclear magnetic resonance--NMR
Journal Article
Chembiochem : a European journal of chemical biology, ISSN 1439-7633, 2018, Volume 19, Issue 14, pp. 1514 - 1522
... (ThDP)‐dependent tetrahedral Breslow intermediate rather than a canonical enamine for catalysis in the biosynthesis of vitamin K. By real... 
thiamine diphosphate | enzyme catalysis | kinetics | vitamin K | Breslow intermediate | Kinetics | Enzyme catalysis | Thiamine diphosphate | Vitamin K | Physiological aspects | Enzymes | Pyrimidines | Biosynthesis | Catalysis | Vitamins | Binding | Spectroscopy | Bioavailability | Substrates | Intermediates | Circular dichroism | Organic chemistry | Decarboxylation | Reaction kinetics | Dichroism | Thiamine
Journal Article
Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, ISSN 0037-9980, 10/2014, Volume 72, Issue 10, pp. 1158 - 1159
The 56-years old "Breslow intermediate" has played a most important role in the umpolung reaction of aldehydes triggered by carbenes such as N-heterocyclic carbenes... 
CHEMISTRY, ORGANIC | BRESLOW INTERMEDIATE
Journal Article
Chemical science (Cambridge), ISSN 2041-6520, 2013, Volume 4, Issue 4, pp. 1514 - 1522
The in situ observation, isolation and reversible formation of intermediate 3-(hydroxybenzyl) azolium salts derived from NHC addition to a range of substituted benzaldehydes is probed... 
THIAMINE ACTION | NUCLEOPHILIC CARBENES | TRIAZOLIUM SALTS | HETEROCYCLIC CARBENE | BRESLOW INTERMEDIATE | UMPOLUNG REACTION | ALPHA,BETA-UNSATURATED ALDEHYDES | HOMOENOLATE EQUIVALENTS | CHEMISTRY, MULTIDISCIPLINARY | THIAZOLIUM SALTS | MICHAEL ADDITION | Chemical equilibrium | Benzoin | Rate constants
Journal Article