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Nature chemical biology, ISSN 1552-4469, 11/2010, Volume 7, Issue 1, pp. 41 - 50
Bruton's tyrosine kinase (Btk) is a therapeutic target for rheumatoid arthritis, but the cellular and molecular mechanisms by which Btk mediates inflammation... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Arthritis, Experimental - drug therapy | Autoantibodies - metabolism | Protein-Tyrosine Kinases - therapeutic use | Arthritis, Experimental - metabolism | Arthritis, Rheumatoid - metabolism | Protein-Tyrosine Kinases - pharmacology | Protein Kinase Inhibitors - chemistry | Benzamides - therapeutic use | Arthritis, Rheumatoid - drug therapy | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Interleukin-1beta - metabolism | Myeloid Cells - immunology | Protein-Tyrosine Kinases - chemistry | Tumor Necrosis Factor-alpha - immunology | Myeloid Cells - drug effects | Benzamides - pharmacology | Phosphorylation - drug effects | Interleukin-6 - metabolism | B-Lymphocytes - metabolism | Benzamides - chemistry | Bridged Bicyclo Compounds, Heterocyclic - chemistry | Interleukin-1beta - immunology | Arthritis, Experimental - immunology | Enzyme Activation - drug effects | B-Lymphocytes - drug effects | Autoantibodies - immunology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | B-Lymphocytes - immunology | Protein Kinase Inhibitors - therapeutic use | Interleukin-6 - immunology | Myeloid Cells - metabolism | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Arthritis, Rheumatoid - immunology | Arthritis | Biochemistry | Inhibitor drugs | Kinases | Binding sites | Index Medicus
Journal Article
Physical chemistry chemical physics : PCCP, ISSN 1463-9084, 2018, Volume 20, Issue 9, pp. 6606 - 6616
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 8/2010, Volume 107, Issue 32, pp. 14309 - 14314
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2005, Volume 46, Issue 4, pp. 595 - 607
Chronic exposure to nicotine elicits upregulation of high-affinity nicotinic receptors in the smoker’s brain. To address the molecular mechanism of... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Membrane Potentials - genetics | Protein Subunits - immunology | Dihydro-beta-Erythroidine - pharmacology | Humans | Pyridines - pharmacokinetics | Nicotinic Antagonists - pharmacology | Patch-Clamp Techniques - methods | Nicotine - pharmacology | Dose-Response Relationship, Drug | Drug Interactions | Transfection - methods | Time Factors | Protein Binding - drug effects | Nicotinic Agonists - pharmacology | Membrane Potentials - drug effects | Cell Line | Blotting, Western - methods | Receptors, Nicotinic - metabolism | Intracellular Space - drug effects | Immunoprecipitation - methods | Bridged Bicyclo Compounds, Heterocyclic - chemistry | Fluorescent Antibody Technique - methods | Autoradiography - methods | Glycosylation | Antibodies - pharmacology | Binding, Competitive - drug effects | Up-Regulation - drug effects | Carbachol - pharmacology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Models, Biological | Intracellular Space - physiology | Receptors, Nicotinic - genetics | Tritium - pharmacokinetics | Bridged Bicyclo Compounds, Heterocyclic - pharmacokinetics | Physiological aspects | Analysis | Nicotine | Proteins | Carbohydrates | Rodents | Molecular weight | Index Medicus | Protein Subunits | Up-Regulation | Immunoprecipitation | Neurons and Cognition | Neurobiology | Antibodies | Tritium | Intracellular Space | Bicyclo Compounds, Heterocyclic | Life Sciences | Transfection | Nicotinic Agonists | Binding, Competitive | Pyridines | Receptors, Nicotinic | Nicotinic Antagonists | Dihydro-beta-Erythroidine | Blotting, Western | Autoradiography | Patch-Clamp Techniques | Membrane Potentials | Carbachol | Fluorescent Antibody Technique | Protein Binding
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 04/2007, Volume 321, Issue 1, pp. 308 - 317
Journal Article