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1. Full Text Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness
by Zdarova Karasova, Jana and Hepnarova, Vendula and Andrys, Rudolf and Lisa, Miroslav and Jost, Petr and Muckova, Lubica and Pejchal, Jaroslav and Herman, David and Jun, Daniel and Kassa, Jiri and Kuca, Kamil
Toxicology letters, ISSN 0378-4274, 03/2020, Volume 320, pp. 64 - 72
cucurbituril | CNS targeting | Mouse | Acetylcholinesterase | Oxime K027 | Sarin | Life Sciences & Biomedicine | Toxicology | Science & Technology | Cholinesterase Reactivators - administration & dosage | Oximes - pharmacokinetics | Humans | Oximes - administration & dosage | Pyridinium Compounds - administration & dosage | Brain - enzymology | Imidazoles - administration & dosage | Male | Imidazoles - pharmacokinetics | Dose-Response Relationship, Drug | Tissue Distribution | Oximes - toxicity | Female | Bridged-Ring Compounds - toxicity | Imidazoles - toxicity | Erythrocytes - enzymology | Pyridinium Compounds - toxicity | A549 Cells | Cell Survival - drug effects | Acetylcholinesterase - blood | Risk Assessment | Injections, Intramuscular | GPI-Linked Proteins - metabolism | Mice, Inbred ICR | Erythrocytes - drug effects | Hep G2 Cells | Brain - drug effects | Pyridinium Compounds - pharmacokinetics | Maximum Tolerated Dose | Animals | GPI-Linked Proteins - blood | Cholinesterase Reactivators - toxicity | Bridged-Ring Compounds - administration & dosage | Bridged-Ring Compounds - pharmacokinetics | Acetylcholinesterase - metabolism | Cholinesterase Reactivators - pharmacokinetics | Index Medicus
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2. Full Text Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial
by Kleckner, Ian R and Kleckner, Ian R and Kamen, Charles and Kamen, Charles and Gewandter, Jennifer S and Gewandter, Jennifer S and Mohile, Nimish A and Mohile, Nimish A and Heckler, Charles E and Heckler, Charles E and Culakova, Eva and Culakova, Eva and Fung, Chunkit and Fung, Chunkit and Janelsins, Michelle C and Janelsins, Michelle C and Asare, Matthew and Asare, Matthew and Lin, Po-Ju and Lin, Po-Ju and Reddy, Pavan S and Reddy, Pavan S and Giguere, Jeffrey and Giguere, Jeffrey and Berenberg, Jeffrey and Berenberg, Jeffrey and Kesler, Shelli R and Kesler, Shelli R and Mustian, Karen M and Mustian, Karen M
Supportive care in cancer, ISSN 0941-4355, 4/2018, Volume 26, Issue 4, pp. 1019 - 1028
Pain Medicine | Nursing | Rehabilitation Medicine | Exercise | Medicine & Public Health | Nursing Research | Oncology | CIPN | Neuropathy | Health Care Sciences & Services | Rehabilitation | Life Sciences & Biomedicine | Science & Technology | Exercise Therapy - methods | Peripheral Nervous System Diseases - chemically induced | Humans | Middle Aged | Vinca Alkaloids - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Peripheral Nervous System Diseases - therapy | Male | Peripheral Nervous System Diseases - physiopathology | Breast Neoplasms - drug therapy | Neoplasms - drug therapy | Taxoids - administration & dosage | Organoplatinum Compounds - administration & dosage | Vinca Alkaloids - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Bridged-Ring Compounds - adverse effects | Female | Neoplasm Staging | Neoplasms - pathology | Bridged-Ring Compounds - administration & dosage | Organoplatinum Compounds - adverse effects | Taxoids - adverse effects | Alkaloids | Chemotherapy | Health aspects | Analysis | Mortality | Cancer | Clinical trials | Breast cancer | Peripheral neuropathy | Evidence-based medicine | Index Medicus | exercise | neuropathy
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3. Full Text Nine weeks versus 1 year adjuvant trastuzumab in combination with chemotherapy: final results of the phase III randomized Short-HER study
by Conte, P and Frassoldati, A and Bisagni, G and Brandes, A A and Donadio, M and Garrone, O and Piacentini, F and Cavanna, L and Giotta, F and Aieta, M and Gebbia, V and Molino, A and Musolino, A and Ferro, A and Maltoni, R and Danese, S and Zamagni, C and Rimanti, A and Cagossi, K and Russo, A and Pronzato, P and Giovanardi, F and Moretti, G and Lombardo, L and Schirone, A and Beano, A and Amaducci, L and Bajardi, E A and Vicini, R and Balduzzi, S and D'Amico, R and Guarneri, V
Annals of oncology, ISSN 0923-7534, 12/2018, Volume 29, Issue 12, pp. 2328 - 2333
Adjuvant | Breast cancer | De-escalated treatment | Trastuzumab | Cardiac safety | Life Sciences & Biomedicine | Oncology | Science & Technology | Anthracyclines - adverse effects | Antineoplastic Agents, Immunological - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Middle Aged | Receptor, ErbB-2 - metabolism | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Cardiotoxicity - epidemiology | Cardiotoxicity - etiology | Breast Neoplasms - therapy | Anthracyclines - administration & dosage | Time Factors | Chemotherapy, Adjuvant - adverse effects | Mastectomy | Adult | Female | Taxoids - adverse effects | Drug Administration Schedule | Chemotherapy, Adjuvant - standards | Neoplasm Recurrence, Local | Trastuzumab - adverse effects | Trastuzumab - administration & dosage | Disease-Free Survival | Taxoids - administration & dosage | Antineoplastic Agents, Immunological - adverse effects | Antineoplastic Combined Chemotherapy Protocols - standards | Breast Neoplasms - pathology | Chemotherapy, Adjuvant - methods | Breast Neoplasms - mortality | Bridged-Ring Compounds - adverse effects | Aged | Neoplasm Staging | Bridged-Ring Compounds - administration & dosage | Index Medicus
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4. Full Text Development and validation of a cycle-specific risk score for febrile neutropenia during chemotherapy cycles 2–6 in patients with solid cancers: The CSR FENCE score
by Aagaard, Theis and Reekie, Joanne and Roen, Ashley and Daugaard, Gedske and Specht, Lena and Sengeløv, Henrik and Mocroft, Amanda and Lundgren, Jens and Helleberg, Marie
International journal of cancer, ISSN 0020-7136, 2019, Volume 146, Issue 2, pp. 321 - 328
g-csf | infection | risk score | prediction | cancer | febrile neutropenia | chemotherapy | prophylaxis | Risk Assessment - methods | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Follow-Up Studies | Chemotherapy-Induced Febrile Neutropenia - etiology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Chemotherapy-Induced Febrile Neutropenia - prevention & control | Male | Incidence | Female | Taxoids - adverse effects | Platinum Compounds - adverse effects | Chemotherapy-Induced Febrile Neutropenia - epidemiology | Drug Administration Schedule | Risk Factors | Granulocyte Colony-Stimulating Factor - therapeutic use | Neoplasms - drug therapy | Taxoids - administration & dosage | Models, Biological | Denmark - epidemiology | Bridged-Ring Compounds - adverse effects | Poisson Distribution | Aged | Platinum Compounds - administration & dosage | Bridged-Ring Compounds - administration & dosage | Index Medicus
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5. Full Text Efficacy of eribulin in women with metastatic breast cancer: a pooled analysis of two phase 3 studies
by Twelves, Chris and Cortes, Javier and Vahdat, Linda and Olivo, Martin and He, Yi and Kaufman, Peter A and Awada, Ahmad
Breast cancer research and treatment, ISSN 0167-6806, 12/2014, Volume 148, Issue 3, pp. 553 - 561
Oncology | Metastatic breast cancer | Medicine & Public Health | Pooled analysis | Eribulin mesylate | Halaven | Life Sciences & Biomedicine | Science & Technology | Anthracyclines - adverse effects | Receptor, ErbB-2 - genetics | Capecitabine | Humans | Middle Aged | Furans - adverse effects | Neoplasm Metastasis | Anthracyclines - administration & dosage | Fluorouracil - administration & dosage | Aged, 80 and over | Adult | Female | Ketones - adverse effects | Taxoids - adverse effects | Fluorouracil - analogs & derivatives | Deoxycytidine - administration & dosage | Ketones - administration & dosage | Breast Neoplasms - drug therapy | Disease-Free Survival | Taxoids - administration & dosage | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Bridged-Ring Compounds - adverse effects | Aged | Bridged-Ring Compounds - administration & dosage | Deoxycytidine - analogs & derivatives | Furans - administration & dosage | Women | Care and treatment | Anthracyclines | Chemotherapy | Analysis | Oncology, Experimental | Breast cancer | Metastasis | Research | Cancer | Index Medicus | Clinical Trial
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6. Full Text Pooled analyses of eribulin in metastatic breast cancer patients with at least one prior chemotherapy
by Pivot, X and Marmé, F and Koenigsberg, R and Guo, M and Berrak, E and Wolfer, A
Annals of oncology, ISSN 0923-7534, 08/2016, Volume 27, Issue 8, pp. 1525 - 1531
clinical trial | triple-negative breast cancer | pooled analysis | metastatic breast cancer | eribulin | survival | Clinical trial | Metastatic breast cancer | Eribulin | Pooled analysis | Survival | Triple-negative breast cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Anthracyclines - adverse effects | Adjuvants, Pharmaceutic | Receptor, ErbB-2 - genetics | Humans | Antineoplastic Agents - therapeutic use | Furans - adverse effects | Triple Negative Breast Neoplasms - drug therapy | Furans - therapeutic use | Randomized Controlled Trials as Topic | Disease-Free Survival | Taxoids - administration & dosage | Clinical Trials, Phase III as Topic | Neoplasm Metastasis | Triple Negative Breast Neoplasms - genetics | Antineoplastic Agents - adverse effects | Triple Negative Breast Neoplasms - pathology | Bridged-Ring Compounds - adverse effects | Female | Ketones - therapeutic use | Receptor, ErbB-2 - antagonists & inhibitors | Anthracyclines - therapeutic use | Bridged-Ring Compounds - administration & dosage | Ketones - adverse effects | Taxoids - adverse effects | Index Medicus | Original
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7. Full Text Ixabepilone Plus Capecitabine for Metastatic Breast Cancer Progressing After Anthracycline and Taxane Treatment
by Eva S. Thomas and Henry L. Gomez and Rubi K. Li and Hyun-Cheol Chung and Luis E. Fein and Valorie F. Chan and Jacek Jassem and Xavier B. Pivot and Judith V. Klimovsky and Fernando Hurtado de Mendoza and Binghe Xu and Mario Campone and Guillermo L. Lerzo and Ronald A. Peck and Pralay Mukhopadhyay and Linda T. Vahdat and Henri H. Roché
Journal of clinical oncology, ISSN 0732-183X, 11/2007, Volume 25, Issue 33, pp. 5210 - 5217
Gynecology. Andrology. Obstetrics | Mammary gland diseases | Biological and medical sciences | Medical sciences | Tumors | Bridged-Ring Compounds - therapeutic use | Fluorouracil - analogs & derivatives | Capecitabine | Deoxycytidine - administration & dosage | Humans | Middle Aged | Breast Neoplasms - drug therapy | Epothilones - adverse effects | Disease Progression | Taxoids - therapeutic use | Neoplasm Metastasis | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Epothilones - administration & dosage | Adult | Breast Neoplasms - mortality | Deoxycytidine - adverse effects | Female | Aged | Anthracyclines - therapeutic use | Deoxycytidine - analogs & derivatives | Index Medicus | Anthracyclines | Antineoplastic Combined Chemotherapy Protocols | Breast Neoplasms | Life Sciences | Immunology | Taxoids | Bridged Compounds | Deoxycytidine | Epothilones | Fluorouracil
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8. Full Text Taxane-Cisplatin-Fluorouracil As Induction Chemotherapy in Locally Advanced Head and Neck Cancers: An Individual Patient Data Meta-Analysis of the Meta-Analysis of Chemotherapy in Head and Neck Cancer Group
by Pierre Blanchard and Jean Bourhis and Benjamin Lacas and Marshall R. Posner and Jan B. Vermorken and Juan J. Cruz Hernandez and Abderrahmane Bourredjem and Gilles Calais and Adriano Paccagnella and Ricardo Hitt and Jean-Pierre Pignon and Meta-Analysis of Chemotherapy in Head and Neck Cancer, Induction Project, Collaborative Group
Journal of clinical oncology, ISSN 0732-183X, 08/2013, Volume 31, Issue 23, pp. 2854 - 2860
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Otorhinolaryngology. Stomatology | Otorhinolaryngology (head neck, general aspects and miscellaneous) | Tumors | Humans | Middle Aged | Head and Neck Neoplasms - drug therapy | Induction Chemotherapy - methods | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Treatment Outcome | Cisplatin - administration & dosage | Randomized Controlled Trials as Topic | Disease-Free Survival | Taxoids - administration & dosage | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cisplatin - adverse effects | Bridged-Ring Compounds - adverse effects | Bridged-Ring Compounds - administration & dosage | Taxoids - adverse effects | Index Medicus
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9. Full Text Effectiveness of an Adjuvant Chemotherapy Regimen for Early-Stage Breast Cancer: A Systematic Review and Network Meta-analysis
by Fujii, Takeo and Le Du, Fanny and Xiao, Lianchun and Kogawa, Takahiro and Barcenas, Carlos H and Alvarez, Ricardo H and Valero, Vicente and Shen, Yu and Ueno, Naoto T
JAMA oncology, ISSN 2374-2437, 09/2015, Volume 1, Issue 9, pp. 1 - 8
Anthracyclines - adverse effects | Cyclophosphamide - administration & dosage | Humans | Treatment Outcome | Breast Neoplasms - drug therapy | Cyclophosphamide - adverse effects | Cisplatin - administration & dosage | Randomized Controlled Trials as Topic | Taxoids - administration & dosage | Anthracyclines - administration & dosage | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cisplatin - adverse effects | Bridged-Ring Compounds - adverse effects | Female | Chemotherapy, Adjuvant | Platinum Compounds - administration & dosage | Bridged-Ring Compounds - administration & dosage | Taxoids - adverse effects | Platinum Compounds - adverse effects | Index Medicus
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10. Full Text A multicenter phase II study of XRP6258 administered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients
by Pivot, X and Koralewski, P and Hidalgo, J.L and Chan, A and Gonçalves, A and Schwartsmann, G and Assadourian, S and Lotz, J.P
Annals of oncology, ISSN 0923-7534, 09/2008, Volume 19, Issue 9, pp. 1547 - 1552
taxane | chemotherapy | resistance | taxoid | metastatic breast cancer | XRP6258 | Resistance | Metastatic breast cancer | Taxoid | Chemotherapy | Taxane | Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | Confidence Intervals | Adenocarcinoma - pathology | Prognosis | Taxoids - pharmacology | Humans | Middle Aged | Drug Resistance, Neoplasm | Antineoplastic Agents - administration & dosage | Dose-Response Relationship, Drug | Bridged-Ring Compounds - pharmacology | Adult | Female | Drug Administration Schedule | Risk Assessment | Kaplan-Meier Estimate | Treatment Outcome | Adenocarcinoma - drug therapy | Breast Neoplasms - drug therapy | Adenocarcinoma - secondary | Taxoids - administration & dosage | Maximum Tolerated Dose | Breast Neoplasms - pathology | Survival Analysis | Breast Neoplasms - mortality | Aged | Infusions, Intravenous | Neoplasm Staging | Adenocarcinoma - mortality | Index Medicus | Adenocarcinoma | Antineoplastic Agents | Breast Neoplasms | Life Sciences | Immunology | Taxoids | Bridged Compounds | Kaplan-Meiers Estimate
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11. Full Text Sensitive analysis and pharmacokinetic study of the isomers paeoniflorin and albiflorin after oral administration of Total Glucosides Of White Paeony Capsule in rats
by Fei, Fei and Yang, Hailing and Peng, Ying and Wang, Pei and Wang, Shuyao and Zhao, Yuqing and Huang, Jingqiu and Yu, Xiaoyi and Feng, Siqi and Sun, Runbin and Yang, Na and Wang, Hongbo and Aa, Jiye and Wang, Guangji
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, ISSN 1570-0232, 06/2016, Volume 1022, pp. 30 - 37
Paeoniflorin | Albiflorin | Tissue distribution | Pharmacokinetics | LC–MS/MS | LC-MS/MS | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Glucosides - blood | Limit of Detection | Reproducibility of Results | Administration, Oral | Rats | Linear Models | Male | Glucosides - pharmacokinetics | Isomerism | Drugs, Chinese Herbal - pharmacokinetics | Monoterpenes - pharmacokinetics | Animals | Bridged-Ring Compounds - chemistry | Paeonia - chemistry | Bridged-Ring Compounds - blood | Drugs, Chinese Herbal - chemistry | Monoterpenes - blood | Chromatography, Liquid | Glucosides - chemistry | Monoterpenes - chemistry | Female | Bridged-Ring Compounds - pharmacokinetics | Tandem Mass Spectrometry - methods | Drugs, Chinese Herbal - analysis | Drugs | Drugstores | Drug delivery systems | Pharmacy | Vehicles | Liquid chromatography | Mass spectrometry | Index Medicus | Excretion | Organs | Bones | Pharmacology | Exposure | Isomers | Glucosides
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12. Full Text Trastuzumab emtansine with or without pertuzumab versus trastuzumab plus taxane for human epidermal growth factor receptor 2-positive, advanced breast cancer: Primary results from the phase III MARIANNE study
by Perez, Edith A and Barrios, Carlos and Eiermann, Wolfgang and Toi, Masakazu and Im, Young-Hyuck and Conte, Pierfranco and Martin, Miguel and Pienkowski, Tadeusz and Pivot, Xavier and Burris, Howard and Petersen, Jennifer A and Stanze, Sven and Strasak, Alexander and Patre, Monika and Ellis, Paul
Journal of clinical oncology, ISSN 0732-183X, 01/2017, Volume 35, Issue 2, pp. 141 - 148
Life Sciences & Biomedicine | Oncology | Science & Technology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Maytansine - analogs & derivatives | Humans | Middle Aged | Drug Tolerance | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Trastuzumab - administration & dosage | Random Allocation | Breast Neoplasms - drug therapy | Taxoids - administration & dosage | Breast Neoplasms - chemistry | Maytansine - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Aged, 80 and over | Quality of Life | Adult | Female | Aged | Receptor, ErbB-2 - analysis | Bridged-Ring Compounds - administration & dosage | Index Medicus | ORIGINAL REPORTS
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13. Full Text A strategy for detecting optimal ratio of cardioprotection-dependent three compounds as quality control of Guan-Xin-Er-Hao formula
by Wang, Yang and Huang, Xi and Qin, Feng and Ren, Ping and Zhu, Zhengyan and Fan, Rong and Zhang, Chunhu and Zhang, Hainan and Tang, Tao and He, Juan and Liu, Zhaoqian and Zhou, Honghao
Journal of ethnopharmacology, ISSN 0378-8741, 01/2011, Volume 133, Issue 2, pp. 735 - 742
Optimal ratio | Traditional Chinese medicine | Guan-Xin-Er-Hao | Absorbed bioactive compounds | Quality control | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Biological and medical sciences | Pharmacognosy. Homeopathy. Health food | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Coumaric Acids - administration & dosage | Apoptosis - drug effects | Caspase 3 - metabolism | Male | Chalcone - analogs & derivatives | Myocardial Infarction - pathology | Chalcone - administration & dosage | Monoterpenes | Quinones - administration & dosage | Drugs, Chinese Herbal - administration & dosage | Phytotherapy | Quality Control | Rats | Cardiotonic Agents - chemistry | Myocardial Infarction - metabolism | Drugs, Chinese Herbal - standards | Rats, Sprague-Dawley | Chemistry, Pharmaceutical | Benzoates - administration & dosage | Drugs, Chinese Herbal - pharmacokinetics | Ethnopharmacology | Animals | Cardiotonic Agents - administration & dosage | Myocardial Infarction - drug therapy | Benzaldehydes - administration & dosage | Glucosides - administration & dosage | Drugs, Chinese Herbal - chemistry | Catechols - administration & dosage | Bridged-Ring Compounds - administration & dosage | Cardiotonic Agents - standards | Medicine, Chinese | Index Medicus
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