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Journal of Experimental Medicine, ISSN 0022-1007, 02/2010, Volume 207, Issue 2, pp. 327 - 337
Production of type I interferon (IFN; IFN-αβ) increases host susceptibility to Listeria monocytogenes , whereas type II IFN (IFN-γ) activates macrophages to... 
Brief Definitive Report
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 05/2007, Volume 204, Issue 5, pp. 995 - 1001
Invariant natural killer T (iNKT) cells are an important source of both T helper type 1 (Th1) and Th2 cytokines, through which they can exert beneficial, as... 
Brief Definitive Reports
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 02/2010, Volume 207, Issue 2, pp. 309 - 318
Phospholipase Cγ1 (PLCγ1) is an important signaling effector of T cell receptor (TCR). To investigate the role of PLCγ1 in T cell biology, we generated and... 
Brief Definitive Report
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 06/2009, Volume 206, Issue 6, pp. 1237 - 1244
Repetitive DNA sequences in the immunoglobulin switch μ region form RNA-containing secondary structures and undergo hypermutation by activation-induced... 
Brief Definitive Report
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2014, Volume 211, Issue 3, pp. 405 - 411
Epitope-specific antibody responses recognized by germline-encoded structures are of significant relevance for the development of autoantibody-mediated... 
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Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 11/2007, Volume 204, Issue 12, pp. 2797 - 2802
We previously reported that joint swelling, synovial thickening, and cartilage matrix depletion induced by the injection of anti-collagen monoclonal antibodies... 
Brief Definitive Reports
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2007, Volume 204, Issue 1, pp. 17 - 23
Mutations at A/T bases within immunoglobulin genes have been shown to be generated by a repair pathway involving the DNA-binding moiety of the mismatch repair... 
Brief Definitive Reports
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2010, Volume 207, Issue 3, pp. 455 - 463
Mast cell production of interleukin-10 (IL-10) can limit the skin pathology induced by chronic low-dose ultraviolet (UV)-B irradiation. Although the mechanism... 
Brief Definitive Report
Journal Article
The Journal of Experimental Medicine, ISSN 0022-1007, 10/2015, Volume 212, Issue 11, pp. 1803 - 1809
Immune cells of myeloid lineage cluster around amyloid-β plaques in the Alzheimer’s disease brain. However, assigning functional roles to myeloid subtypes,... 
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Journal Article
The Journal of Experimental Medicine, ISSN 0022-1007, 03/2015, Volume 212, Issue 3, pp. 287 - 295
Jay and colleagues show that TREM2 deficiency reduces the number of macrophages infiltrating the brain and is protective against disease pathogenesis in mouse... 
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Journal of Experimental Medicine, ISSN 0022-1007, 05/2007, Volume 204, Issue 5, pp. 979 - 985
Dengue virus infection is an increasingly important tropical disease, causing 100 million cases each year. Symptoms range from mild febrile illness to severe... 
Brief Definitive Reports
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2011, Volume 208, Issue 7, pp. 1367 - 1376
Upon antigen stimulation, the bioenergetic demands of T cells increase dramatically over the resting state. Although a role for the metabolic switch to... 
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Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 12/1996, Volume 184, Issue 6, pp. 2417 - 2422
Transforming growth factor β1 (TGF-β1) regulates leukocytes and epithelial cells. To determine whether the pleiotropic effects of TGF-β1, a cytokine that is... 
Brief Definitive Report
Journal Article
The Journal of Experimental Medicine, ISSN 0022-1007, 10/2008, Volume 205, Issue 11, pp. 2499 - 2506
textabstractMost chromosomal translocations in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) involve oncogenes that are either up-regulated... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNOLOGY | CANCER | MICRORNA SIGNATURES | GENES | Brief Definitive Reports
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2007, Volume 204, Issue 11, pp. 2545 - 2552
Langerhans cells (LCs) are bone marrow (BM)–derived epidermal dendritic cells (DCs) that develop from precursors found in the dermis. Epidermal LCs are absent... 
Brief Definitive Reports
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 04/2005, Volume 201, Issue 7, pp. 1061 - 1067
Transforming growth factor (TGF)-β1 is a major pluripotential cytokine with a pronounced immunosuppressive effect and its deficiency results in lethal... 
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Journal Article
The Journal of Experimental Medicine, ISSN 0022-1007, 01/2012, Volume 209, Issue 1, pp. 1 - 10
When fused to a rabies virus glycoprotein peptide that shuttles small RNAs across the blood–brain barrier, an HCMV noncoding RNA that protects mitochondrial... 
Brief Definitive Report
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 06/2017, Volume 214, Issue 6, pp. 1567 - 1580
The liver provides a tolerogenic immune niche exploited by several highly prevalent pathogens as well as by primary and metastatic tumors. We have sampled... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | MAINTENANCE | HEPATOCYTES | HEPATITIS | RECOGNITION | TOLERANCE | EXPANSION | ACCUMULATION | IMMUNOLOGY | EXPRESSION | ANTIGEN
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2007, Volume 204, Issue 7, pp. 1533 - 1541
It has been recently shown (Seddiki, N., B. Santner-Nanan, J. Martinson, J. Zaunders, S. Sasson, A. Landay, M. Solomon, W. Selby, S.I. Alexander, R. Nanan, et... 
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