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AAPS PharmSciTech, ISSN 1530-9932, 12/2011, Volume 12, Issue 4, pp. 1087 - 1101
In the present study, an effort was made to design prolonged release Eudragit nanoparticles of brimonidine tartrate by double emulsion–solvent evaporation... 
Biochemistry, general | Biotechnology | Biomedicine | nanoparticles | intraocular pressure | brimonidine tartrate | Pharmacy | glaucoma | Pharmacology/Toxicology | Eudragit | DRUG-DELIVERY | ALGINATE | CHITOSAN NANOPARTICLES | TOXICITY | TIMOLOL | DISPOSITION | ACID NANOPARTICLES | NANOSPHERES | PHARMACOLOGY & PHARMACY | RABBIT | Administration, Ophthalmic | Intraocular Pressure - drug effects | Adrenergic alpha-2 Receptor Agonists - chemistry | Adrenergic alpha-2 Receptor Agonists - pharmacology | Drug Carriers | Dose-Response Relationship, Drug | Nanoparticles | Quinoxalines - pharmacology | Adrenergic alpha-2 Receptor Agonists - administration & dosage | Quinoxalines - toxicity | Drug Compounding | Glaucoma - physiopathology | Disease Models, Animal | Rabbits | Quinoxalines - administration & dosage | Drug Stability | Solubility | Quinoxalines - chemistry | Glaucoma - drug therapy | Technology, Pharmaceutical - methods | Brimonidine Tartrate | Acrylic Resins - chemistry | Chemistry, Pharmaceutical | Adrenergic alpha-2 Receptor Agonists - toxicity | Animals | Acrylic Resins - toxicity | Kinetics | Delayed-Action Preparations | Nanotechnology | Hydrogen-Ion Concentration | Drugs | Glaucoma | Drug delivery systems | Lecithin | Sulfonamides | Sympathomimetic agents | Brimonidine | Dosage and administration | Plant lipids | Ophthalmology | Vehicles | Drugstores | Indexing in process | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 12/2015, Volume 220, Issue Pt A, pp. 180 - 188
Journal Article
Pharmaceutical Development and Technology, ISSN 1083-7450, 03/2018, Volume 23, Issue 3, pp. 231 - 239
Systemic absorption of ocularly administered Brimonidine Tartrate has been reported to give rise to several side-effects. Hence, it has become crucial to... 
Brimonidine tartrate | systemic absorption | UPLC-MS/MS | intraocular pressure | ophthalmic gels | UPLC–MS/MS | UPLC-MS | IN-VITRO | VIVO | DRUG-DELIVERY | PHARMACOLOGY & PHARMACY | Index Medicus
Journal Article
Journal of Drug Delivery Science and Technology, ISSN 1773-2247, 04/2016, Volume 32, pp. 21 - 30
The glaucoma is an ocular pathology characterized by the increase of intraocular pressure and possibility of retinal degeneration. The treatment is based on... 
Glaucoma | Brimonidine tartrate | Inserts based on chitosan and brimonidine tartrate | Chitosan | Chorioallantoic membrane | Ocular inserts
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e47098 - e47098
Glutamate excitotoxicity-induced oxidative stress have been linked to mitochondrial dysfunction in retinal ischemia and optic neuropathies including glaucoma.... 
OPTIC-NERVE | PROAPOPTOTIC BAX | APOPTOTIC CELL-DEATH | MULTIDISCIPLINARY SCIENCES | RAT RETINA | GANGLION-CELLS | DBA/2J MOUSE | DNA DAMAGE | NMDA RECEPTOR FUNCTION | GLAUCOMA | SUPEROXIDE-DISMUTASE | Retina - drug effects | Retina - metabolism | Retinal Diseases - chemically induced | Receptors, Adrenergic, alpha-2 - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Retinal Diseases - metabolism | Mitochondrial Proteins - genetics | DNA-Binding Proteins - metabolism | Oxidative Phosphorylation - drug effects | Retinal Ganglion Cells - cytology | Adrenergic alpha-2 Receptor Agonists | Mitochondrial Proteins - metabolism | bcl-Associated Death Protein - metabolism | Superoxide Dismutase - metabolism | Quinoxalines - therapeutic use | bcl-2-Associated X Protein - metabolism | Ischemia - metabolism | Rats | Brimonidine Tartrate | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Animals | Ischemia - drug therapy | Oxidative Stress - drug effects | Retinal Diseases - drug therapy | Glutamic Acid - toxicity | Ischemia - chemically induced | Retinal Ganglion Cells - drug effects | Glaucoma | Methyl aspartate | Oxidative stress | Brimonidine | Ischemia | Glutamate | Neuroprotection | Neurosciences | Transcription factors | Phosphorylation | Traumatic brain injury | Bax protein | Laboratories | Retina | Superoxide dismutase | Biology | Mitochondrial DNA | Glutamic acid receptors | Proteins | Receptors | Mitochondria | Bcl-x protein | Neurodegeneration | Rodents | Excitation | Injuries | Deoxyribonucleic acid--DNA | Stresses | Optic nerve | Preservation | N-Methyl-D-aspartic acid receptors | Gene expression | Stress | Retinal ganglion cells | Brain research | Molecular modelling | Oxidative phosphorylation | Microscopy | Excitotoxicity | Bad protein | Protein expression | Hypoxia | Adrenergic receptors | Bone mineral density | Immunoreactivity | Intraocular pressure | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology, ISSN 0412-4081, 11/2013, Volume 49, Issue 11, p. 973
To investigate the protective effects of sodium hyaluronate on ocular surface toxicity induced by a prolonged use of benzalkonium chloride-preserved... 
Rabbits | Animals | Cornea - drug effects | Quinoxalines - toxicity | Conjunctiva - drug effects | Benzalkonium Compounds - toxicity | Female | Hyaluronic Acid - pharmacology | Brimonidine Tartrate | Ophthalmic Solutions - toxicity
Journal Article
Graefe's Archive for Clinical and Experimental Ophthalmology, ISSN 0721-832X, 8/2015, Volume 253, Issue 8, pp. 1291 - 1296
Journal Article