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Hippocampus, ISSN 1050-9631, 10/2017, Volume 27, Issue 10, pp. 1093 - 1109
Exposure to excessive or uncontrolled stress is a major factor associated with various diseases including posttraumatic stress disorder (PTSD). The... 
URB597 | LTP | CB1 | extinction | posttraumatic stress disorder (PTSD) | receptors | CONDITIONED TASTE-AVERSION | BASOLATERAL AMYGDALA | CONTEXTUAL FEAR | ENDOCANNABINOID SYSTEM | EMOTIONAL MEMORY | SYNAPTIC PLASTICITY | NEUROSCIENCES | VENTRAL TEGMENTAL AREA | GLUCOCORTICOID-RECEPTOR ACTIVATION | CB1 RECEPTOR | PITUITARY-ADRENAL AXIS | Cannabinoid Receptor Modulators - pharmacology | Memory - drug effects | Amygdala - physiopathology | Amygdala - drug effects | Stress Disorders, Post-Traumatic - pathology | Fear - drug effects | Neuronal Plasticity - drug effects | Male | Hippocampus - drug effects | Stress Disorders, Post-Traumatic - physiopathology | Fear - physiology | Receptors, Cannabinoid - metabolism | Neuronal Plasticity - physiology | Piperidines - pharmacology | Stress Disorders, Post-Traumatic - drug therapy | Benzamides - pharmacology | Carbamates - pharmacology | Disease Models, Animal | Pyrazoles - pharmacology | Amidohydrolases - metabolism | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Amidohydrolases - antagonists & inhibitors | Hippocampus - pathology | Stress Disorders, Post-Traumatic - psychology | Avoidance Learning - physiology | Magnesium - pharmacology | Rats, Sprague-Dawley | Amygdala - pathology | Cannabinoids - pharmacology | Naphthalenes - pharmacology | Animals | Benzoxazines - pharmacology | Glutamates - pharmacology | Avoidance Learning - drug effects | Bromine - pharmacology | Electroshock | Hippocampus - physiopathology | Drug Combinations | Memory - physiology | Prevention | Phenols | Cannabinoids | Fatty acids | Analysis | Post-traumatic stress disorder | Potentiation | Fatty-acid amide hydrolase | Shock | Amygdala | Hydrolase | Extinction | Long-term potentiation | Taste aversion | Cannabinoid CB1 receptors | Plasticity (hippocampal) | Trauma | Animal behavior | Rodents | Short term memory | Hippocampus | Long-term effects
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 01/2016, Volume 41, Issue 2, pp. 568 - 577
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2010, Volume 18, Issue 3, pp. 1297 - 1311
Journal Article
Marine Drugs, ISSN 1660-3397, 05/2017, Volume 15, Issue 5, p. 133
Marine molluscs are rich in biologically active natural products that provide new potential sources of anti-inflammatory agents. Here we used bioassay guided... 
Inflammation | Tyrian purple | NO inhibition | Muricidae | Isatin | Marine natural products | CANCER-CELLS | DICATHAIS-ORBITA | SIGNALING PATHWAYS | CHEMISTRY, MEDICINAL | INDIRUBIN DERIVATIVES | NATURAL-PRODUCTS | DNA-DAMAGE | marine natural products | INDUCE APOPTOSIS | isatin | TYRIAN PURPLE PRECURSORS | inflammation | NITRIC-OXIDE | NF-KAPPA-B | Inflammation - chemically induced | Tumor Necrosis Factor-alpha - metabolism | Isatin - pharmacology | NF-kappa B - metabolism | Structure-Activity Relationship | Isatin - chemistry | Mollusca - chemistry | Hydrocarbons, Brominated - pharmacology | Isatin - analogs & derivatives | Inflammation - metabolism | Inflammation - drug therapy | Indoles - pharmacology | Hydrocarbons, Brominated - chemistry | Aquatic Organisms - chemistry | Cell Line | Dinoprostone - pharmacology | Anti-Inflammatory Agents - pharmacology | Dinoprostone - metabolism | Macrophages - metabolism | Animals | Anti-Inflammatory Agents - chemistry | Lipopolysaccharides - pharmacology | Macrophages - drug effects | RAW 264.7 Cells | Mice | Nitric Oxide - metabolism | Indoles - chemistry | 3T3 Cells | Drugs | Products | Necroses | Calcium | Bromination | Indole | Prostaglandin E2 | Mollusks | Structure-activity relationships | Macrophages | Eggs | Lipopolysaccharides | Reduction | Fibroblasts | Inhibition | Indoles | Marine molluscs | Translocation | Bromine | Fractionation | Antiinflammatory agents | Bioassay | Bioassays | Agents | Mode of action | Tumor necrosis factor | Natural products | Nitric oxide | Benzene | Freshwater molluscs | Tumors
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, pp. e112059 - e112059
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2008, Volume 51, Issue 20, pp. 6503 - 6511
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8428 - 8433
Voltage-gated sodium channels are important targets for the development of pharmaceutical drugs, because mutations in different human sodium channel isoforms... 
Sodium channels | Bromine | Maps | Sodium | Channel blockers | Crystals | Atoms | Binding sites | Crystal structure | Local anesthetics | Pharmacology | QUALITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | NA+ CHANNELS | MOLECULAR DETERMINANTS | INHIBITION | LOCAL-ANESTHETICS | LIDOCAINE | pharmacology | DRUGS | crystal structure | STATE-DEPENDENT BLOCK | BINDING | Humans | NAV1.1 Voltage-Gated Sodium Channel - genetics | Bacterial Proteins - chemistry | Molecular Sequence Data | Crystallography, X-Ray | NAV1.1 Voltage-Gated Sodium Channel - metabolism | NAV1.1 Voltage-Gated Sodium Channel - chemistry | Ion Channel Gating - physiology | HEK293 Cells | Sodium Channels - metabolism | Membrane Potentials - drug effects | Protein Structure, Tertiary | Amino Acid Sequence | Triazines - metabolism | Triazines - pharmacology | Alphaproteobacteria - metabolism | Bacterial Proteins - genetics | Models, Molecular | Sodium Channel Blockers - metabolism | Sodium Channel Blockers - pharmacology | Binding Sites - genetics | Membrane Potentials - physiology | Alphaproteobacteria - chemistry | Sequence Homology, Amino Acid | Alphaproteobacteria - genetics | Ion Channel Gating - genetics | Sodium Channels - chemistry | Bacterial Proteins - metabolism | Sodium Channels - genetics | Mutation | Ion Channel Gating - drug effects | Physiological aspects | Prokaryotes | Biological Sciences
Journal Article