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Neuron, ISSN 0896-6273, 2005, Volume 47, Issue 6, pp. 817 - 831
The molecular mechanisms controlling the differentiation of neural progenitors into distinct subtypes of neurons during neocortical development are unknown.... 
AREA IDENTITY | NEOCORTICAL NEURONS | CELL FATE SPECIFICATION | CEREBRAL CORTICAL DEVELOPMENT | LAYER NEURONS | CENTRAL-NERVOUS-SYSTEM | SUBCORTICAL TARGETS | ZINC-FINGER GENE | SUBVENTRICULAR ZONE | NEUROSCIENCES | ZEBRAFISH FOREBRAIN | Membrane Glycoproteins - metabolism | Embryo, Mammalian | Homeodomain Proteins - metabolism | Nerve Tissue Proteins - deficiency | S100 Proteins - genetics | POU Domain Factors - genetics | Forkhead Transcription Factors - metabolism | In Situ Hybridization - methods | Repressor Proteins - metabolism | Gene Expression Regulation, Developmental - physiology | POU Domain Factors - metabolism | Animals, Newborn | DNA-Binding Proteins - physiology | Motor Neurons - physiology | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cell Cycle Proteins - metabolism | S100 Proteins - metabolism | In Situ Nick-End Labeling - methods | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Immunohistochemistry - methods | Annexin A2 - genetics | Cell Death - physiology | Green Fluorescent Proteins - biosynthesis | Mice | Annexin A2 - metabolism | Age Factors | Phosphopyruvate Hydratase - metabolism | Cell Movement - physiology | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | Amino Acids - metabolism | Motor Neurons - cytology | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Membrane Proteins - metabolism | Bromodeoxyuridine - metabolism | Cell Differentiation - physiology | Pyramidal Tracts - physiology | Nerve Tissue Proteins - physiology | Neocortex - growth & development | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cell Count - methods | Neocortex - cytology | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Neurosciences | Neurons | Developmental biology | Stem cells | Studies | Brain | Ultrasonic imaging | Transcription factors | Hybridization | Neurogenesis | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 2003, Volume 40, Issue 3, pp. 485 - 499
The CNS is thought to develop from self-renewing stem cells that generate neurons, astrocytes, and oligodendrocytes. Other data, however, have suggested that... 
OLIGODENDROCYTE LINEAGE | PROGENITOR CELLS | TRANSCRIPTION FACTORS | GLIAL-RESTRICTED PRECURSORS | RAT CEREBRAL-CORTEX | SONIC HEDGEHOG | EMBRYONIC SPINAL-CORD | NEURAL-TUBE | CENTRAL-NERVOUS-SYSTEM | MAMMALIAN FOREBRAIN | NEUROSCIENCES | Immunohistochemistry | Green Fluorescent Proteins | O Antigens - metabolism | Embryo, Mammalian | Cell Count | Homeodomain Proteins - metabolism | Fibroblast Growth Factor 2 - pharmacology | Glial Fibrillary Acidic Protein - metabolism | Hedgehog Proteins | RNA, Messenger - biosynthesis | Time Factors | SOXE Transcription Factors | Neurons - metabolism | Basic Helix-Loop-Helix Transcription Factors | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Enzyme Inhibitors - pharmacology | Proteoglycans - metabolism | Rats | Oligodendrocyte Transcription Factor 2 | Mice | Astrocytes - metabolism | Oligodendroglia - metabolism | Flow Cytometry - methods | Epithelial Cells - metabolism | Epithelial Cells - drug effects | PAX7 Transcription Factor | Carbocyanines - metabolism | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Tubulin - metabolism | Transfection | Reverse Transcriptase Polymerase Chain Reaction - methods | beta-Galactosidase - metabolism | Fibroblast Growth Factor 2 - physiology | Bromodeoxyuridine - metabolism | Spinal Cord - cytology | Cell Differentiation - physiology | High Mobility Group Proteins - metabolism | Cells, Cultured | Antigens - metabolism | Body Patterning - physiology | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Spinal Cord - embryology | Blotting, Northern | Animals | Cell Aggregation | Stem Cells - physiology | Trans-Activators - metabolism | Epidermal Growth Factor - pharmacology | In Vitro Techniques | Luminescent Proteins - metabolism | Spinal cord | Scholarships & fellowships | Neurosciences | Rodents | Stem cells | Experiments | Neurogenesis | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 02/2015, Volume 17, Issue 2, pp. 183 - 194
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 01/2013, Volume 521, Issue 1, pp. 233 - 251
The cells surrounding the central canal of the spinal cord are a source of stem/precursor cells that may give rise to neurons, astrocytes, or oligodendrocytes.... 
spinal cord injury | stem cells | quiescence | ependyma | tanycyte | neural precursor | Tanycyte | Neural precursor | Ependyma | Spinal cord injury | Stem cells | Quiescence | PROGENITOR PROLIFERATION | ENDOCANNABINOID SYSTEM | MONOCLONAL-ANTIBODY | SUBVENTRICULAR ZONE | GENERATE NEURONS | NEUROSCIENCES | NEURAL STEM-CELLS | IN-VITRO | ZOOLOGY | ADULT-RAT | CENTRAL-NERVOUS-SYSTEM | FLUID-CONTACTING NEURONS | Nestin | Rats, Wistar | Cell Count | Ki-67 Antigen - metabolism | Male | Fatty Acid-Binding Proteins - metabolism | Glial Fibrillary Acidic Protein - metabolism | Lewis X Antigen - metabolism | SOXB1 Transcription Factors - metabolism | Spinal Cord Injuries - pathology | Tubulin - metabolism | Ependyma - cytology | Lamins - metabolism | Microfilament Proteins - metabolism | Neurons - metabolism | Bromodeoxyuridine - metabolism | Neural Cell Adhesion Molecule L1 - metabolism | Gene Expression Regulation, Developmental - physiology | Animals, Newborn | Calcium-Binding Proteins - metabolism | Spinal Cord Injuries - metabolism | Mice, Inbred C57BL | Sialic Acids - metabolism | Rats | Fatty Acid-Binding Protein 7 | Spinal Cord - anatomy & histology | Excitatory Amino Acid Transporter 1 - metabolism | Mice, Knockout | Nerve Tissue Proteins - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Animals | Receptor, Cannabinoid, CB1 - genetics | Neuroglia - metabolism | Mice | Receptor, Cannabinoid, CB1 - deficiency | Intermediate Filament Proteins - metabolism | Index Medicus | Astrocytes
Journal Article
Nature Neuroscience, ISSN 1097-6256, 11/2003, Volume 6, Issue 11, pp. 1162 - 1168
The generation of neurons from stem cells involves the activity of proneural basic helix-loop-helix (bHLH) proteins, but the mechanism by which these proteins... 
VENTRAL NEURAL-TUBE | SOX2 | NERVOUS-SYSTEM | STEM-CELLS | BHLH PROTEIN | GENE-EXPRESSION | NEURONAL DIFFERENTIATION | CHICK-EMBRYO | ACHAETE-SCUTE | FATE | NEUROSCIENCES | Helix-Loop-Helix Motifs - physiology | Homeodomain Proteins - metabolism | PAX7 Transcription Factor | Phosphopyruvate Hydratase - metabolism | DNA-Binding Proteins - metabolism | Stem Cells | Tubulin - metabolism | Time Factors | Gene Expression Regulation, Developmental | Neurons - metabolism | Bromodeoxyuridine - metabolism | Membrane Glycoproteins | Spinal Cord - cytology | SOXB1 Transcription Factors | Cell Differentiation - physiology | Basic Helix-Loop-Helix Transcription Factors | DNA-Binding Proteins - physiology | HMGB Proteins | High Mobility Group Proteins - metabolism | Drosophila | Embryonic Induction | Neuropeptides - metabolism | Nuclear Proteins - metabolism | Electroporation - methods | Chick Embryo | Proto-Oncogene Proteins c-myc - metabolism | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Spinal Cord - embryology | Vertebrates | Animals | Eye Proteins - metabolism | Spinal Cord - physiology | Avian Proteins | LIM-Homeodomain Proteins | High Mobility Group Proteins - physiology | Mice | Nuclear Proteins - physiology | Neurofilament Proteins - metabolism | Physiological aspects | Research | DNA binding proteins | Neurons | Cell cycle | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 11/2004, Volume 7, Issue 11, pp. 1233 - 1241
Establishing the cellular identity in vivo of adult multipotent neural progenitors is fundamental to understanding their biology. We used two transgenic... 
SITE-SPECIFIC RECOMBINATION | NEURAL STEM-CELLS | RADIAL GLIAL-CELLS | FIBRILLARY ACIDIC PROTEIN | IN-VIVO | CENTRAL-NERVOUS-SYSTEM | SUBVENTRICULAR ZONE | MAMMALIAN FOREBRAIN | NEUROSCIENCES | INTERMEDIATE-FILAMENT PROTEIN | TRANSGENIC MICE | Glial Fibrillary Acidic Protein - genetics | Microtubule-Associated Proteins - metabolism | Phosphopyruvate Hydratase - metabolism | Prosencephalon - physiology | Olfactory Bulb - metabolism | Hippocampus - drug effects | Glial Fibrillary Acidic Protein - metabolism | Prosencephalon - drug effects | Tubulin - metabolism | Neurons - physiology | beta-Galactosidase - metabolism | Ganciclovir - pharmacology | Integrases - metabolism | Bromodeoxyuridine - metabolism | Neural Cell Adhesion Molecule L1 - metabolism | Cell Differentiation - physiology | Olfactory Bulb - cytology | Green Fluorescent Proteins - metabolism | Thymidine Kinase - genetics | Neuroglia - physiology | Sialic Acids - metabolism | Gene Expression Regulation - physiology | Cell Size | Mice, Transgenic | Neuropeptides - metabolism | Hippocampus - cytology | Gene Expression Regulation - drug effects | Immunohistochemistry - methods | Hippocampus - metabolism | Animals | Cell Count - methods | Analysis of Variance | Cell Differentiation - drug effects | Prosencephalon - cytology | Stem Cells - drug effects | Stem Cells - physiology | Mice | Olfactory Bulb - drug effects | Physiological aspects | Brain | Cellular proteins | Research | Neurons | Index Medicus
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 01/2005, Volume 21, Issue 1, pp. 1 - 14
Progress in the field of neurogenesis is currently limited by the lack of tools enabling fast and quantitative analysis of neurogenesis in the adult brain.... 
Neuronal differentiation | Neural stem cells | Neurogenesis indicator | Neuronal progenitor | neuronal progenitor | neural stem cells | LONG-TERM SURVIVAL | ALZHEIMERS-DISEASE | SUBVENTRICULAR ZONE | NEUROSCIENCES | neuronal differentiation | NEURAL STEM-CELLS | FIBROBLAST GROWTH FACTOR-2 | RAT DENTATE GYRUS | OLFACTORY-BULB | NEWLY GENERATED NEURONS | neurogenesis indicator | SPINAL-CORD-INJURY | HIPPOCAMPAL NEUROGENESIS | Cell Proliferation | Microtubule-Associated Proteins - metabolism | Cell Count | Phosphopyruvate Hydratase - metabolism | Seizures - metabolism | Glial Fibrillary Acidic Protein - metabolism | Stem Cells - metabolism | Seizures - chemically induced | Behavior, Animal | Brain - metabolism | Time Factors | Scopolamine Hydrobromide | Female | Laminectomy - methods | Neurons - metabolism | Bromodeoxyuridine - metabolism | Indoles | Cell Differentiation - physiology | Ganglia, Spinal | Organ Culture Techniques | Animals, Newborn | Brain - cytology | Spinal Cord Injuries - metabolism | GAP-43 Protein - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation - physiology | Cell Size | Neuropeptides - metabolism | Immunohistochemistry - methods | Animals | Running | Mice | Neurofilament Proteins - metabolism | Index Medicus | Immunohistochemistry | Brain | cytology | methods | GAP-43 Protein | Bromodeoxyuridine | Neuropeptides | Laminectomy | MEDICIN OCH HÄLSOVETENSKAP | Glial Fibrillary Acidic Protein | Stem Cells | diagnostic use | Cell Differentiation | Cultured | Behavior | MEDICAL AND HEALTH SCIENCES | Seizures | Scopolamine | chemically induced | Neurons | Gene Expression Regulation | physiology | Microtubule-Associated Proteins | Phosphopyruvate Hydratase | Cells | Ganglia | Inbred C57BL | Spinal | Newborn | Spinal Cord Injuries | Animal | Neurofilament Proteins | metabolism
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 47, Issue 6, pp. 803 - 815
Hippocampal activity influences neurogenesis in the adult dentate gyrus; however, little is known about the involvement of the hippocampal circuitry in this... 
RAT DENTATE GYRUS | TEMPORAL-LOBE EPILEPSY | POSTNATAL MOUSE-BRAIN | PROLIFERATING CELLS | GENERATED GRANULE CELLS | CORTICAL CIRCUIT FORMATION | BEHAVING RAT | GAMMA OSCILLATIONS | PSA-NCAM | PRECURSOR CELLS | NEUROSCIENCES | Calcium - metabolism | gamma-Aminobutyric Acid - metabolism | Ki-67 Antigen - metabolism | N-Methylaspartate - pharmacology | Calbindins | Drug Interactions | Neurons - ultrastructure | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neurons - metabolism | Tetrodotoxin - pharmacology | Microscopy, Immunoelectron - methods | Nickel - pharmacology | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | Membrane Potentials - drug effects | Sialic Acids - metabolism | gamma-Aminobutyric Acid - pharmacology | Mice, Transgenic | Excitatory Amino Acid Agonists - pharmacology | Bicuculline - pharmacology | GABA Antagonists - pharmacology | Immunohistochemistry - methods | Vesicular Inhibitory Amino Acid Transport Proteins - metabolism | Glycine - pharmacology | Green Fluorescent Proteins - biosynthesis | Mice | Nestin | Phosphopyruvate Hydratase - metabolism | Sodium-Potassium-Chloride Symporters - metabolism | Patch-Clamp Techniques - methods | Neurons - classification | Intermediate Filament Proteins - genetics | Bromodeoxyuridine - metabolism | Neural Cell Adhesion Molecule L1 - metabolism | Neurons - drug effects | Cell Differentiation - physiology | Electric Stimulation - methods | History, Ancient | Hippocampus - cytology | Membrane Potentials - physiology | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | S100 Calcium Binding Protein G - metabolism | Animals | Cell Count - methods | Solute Carrier Family 12, Member 2 | Cell Differentiation - drug effects | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Stem Cells - drug effects | In Vitro Techniques | GABA | Neurons | Cell research | Studies | Brain | Neurotransmitters | Microscopy | Neurogenesis | Rodents | Index Medicus
Journal Article
Brain Structure and Function, ISSN 1863-2653, 7/2015, Volume 220, Issue 4, pp. 2027 - 2042
The adult dentate gyrus produces new neurons that morphologically and functionally integrate into the hippocampal network. In the adult brain, most excitatory... 
Neurology | Neurosciences | Dentate gyrus | Biomedicine | Synaptogenesis | Astrocytes | Adult neurogenesis | Perisynaptic processes | Cell Biology | 3-DIMENSIONAL RELATIONSHIPS | ANATOMY & MORPHOLOGY | GLUTAMATE UPTAKE | NEUROSCIENCES | ENHANCED SYNAPTIC PLASTICITY | DENDRITIC SPINES | PATTERN SEPARATION | CNS SYNAPTOGENESIS | EXCITATORY SYNAPSES | RAT HIPPOCAMPUS | LONG-TERM POTENTIATION | Glial Fibrillary Acidic Protein - genetics | Synaptic Transmission - genetics | Retinal Dehydrogenase - metabolism | Kainic Acid - analogs & derivatives | Neurons - cytology | Phosphopyruvate Hydratase - metabolism | Dendritic Spines - metabolism | Green Fluorescent Proteins - genetics | Glial Fibrillary Acidic Protein - metabolism | Excitatory Postsynaptic Potentials - drug effects | Microscopy, Immunoelectron | Neurogenesis - genetics | Dendritic Spines - drug effects | Isoenzymes - metabolism | Synaptic Transmission - drug effects | Neurogenesis - drug effects | S100 Calcium Binding Protein beta Subunit - metabolism | Bromodeoxyuridine - metabolism | Neurons - drug effects | Excitatory Postsynaptic Potentials - genetics | Green Fluorescent Proteins - metabolism | Gene Expression Regulation - genetics | Isoenzymes - genetics | Synapses - physiology | Kainic Acid - pharmacology | Mice, Inbred C57BL | Mice, Transgenic | Synapses - ultrastructure | Retinal Dehydrogenase - genetics | Hippocampus - cytology | Astrocytes - ultrastructure | Microscopy, Confocal | Astrocytes - physiology | Patch-Clamp Techniques | Animals | Mice | Brain | Adults | Glutamate | Neurons | Resveratrol | Cells | Index Medicus | Original
Journal Article