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Journal of Experimental Medicine, ISSN 0022-1007, 06/2002, Volume 195, Issue 11, pp. 1433 - 1444
Interleukin (IL)-5 and IL-13 are thought to play key roles in the pathogenesis of asthma. Although both cytokines use eotaxin to regulate eosinophilia, IL-13... 
Allergy | Inflammation | Cytokines | Lung | Eosinophils | MEDICINE, RESEARCH & EXPERIMENTAL | TISSUE EOSINOPHILIA | BRONCHIAL BIOPSIES | MESSENGER-RNA EXPRESSION | BONE-MARROW | allergy | eosinophils | IMMUNOLOGY | BRONCHOALVEOLAR LAVAGE | lung | LUNG DAMAGE | MURINE MODEL | inflammation | ALLERGEN INHALATION CHALLENGE | cytokines | GUINEA-PIG MODEL | ATOPIC ASTHMA | Eosinophilia - metabolism | Asthma - metabolism | Eosinophils - metabolism | Eosinophils - transplantation | Bronchial Hyperreactivity - immunology | Chemokines, CC - blood | Humans | Th2 Cells - immunology | Adoptive Transfer | Interleukin-5 - genetics | RNA, Messenger - metabolism | CD4-Positive T-Lymphocytes - immunology | Eosinophilia - pathology | Interleukin-13 - biosynthesis | Gene Deletion | Asthma - immunology | Bronchial Hyperreactivity - metabolism | Disease Models, Animal | Signal Transduction | Interleukin-5 - metabolism | RNA, Messenger - genetics | CD4-Positive T-Lymphocytes - metabolism | Chemokine CCL11 | Interleukin-13 - metabolism | Bronchial Hyperreactivity - complications | Th2 Cells - metabolism | Interleukin-5 - blood | Sputum - metabolism | Bronchial Hyperreactivity - pathology | Animals | Eosinophilia - immunology | Asthma - complications | Chemokines, CC - genetics | Eosinophilia - complications | Mice | Mice, Inbred BALB C | Interleukin-18 - metabolism | Chemokines, CC - metabolism
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 08/2011, Volume 45, Issue 2, pp. 366 - 375
The effects of a newly synthesized docosahexaenoic acid (DHA) derivative, CRBM-0244, on lung inflammation and airway hyperresponsiveness were determined in an... 
CPI-17 | Inflammation | DHA | Airway hyperresponsiveness | Asthma | airway hyperresponsiveness | ACTIVATION | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN BRONCHI | asthma | NECROSIS-FACTOR-ALPHA | HYPERRESPONSIVENESS | CELL BIOLOGY | inflammation | RESPIRATORY SYSTEM | DAMPENS AIRWAY INFLAMMATION | PPAR-GAMMA | TNF-ALPHA | SMOOTH-MUSCLE CONTRACTION | Asthma - metabolism | Asthma - prevention & control | Calcium - metabolism | Humans | Phosphoprotein Phosphatases - metabolism | Pneumonia - pathology | Pneumonia - prevention & control | Lung Neoplasms - pathology | Male | NF-kappa B - metabolism | Monoglycerides - pharmacology | Bronchi - drug effects | Muscle, Smooth - drug effects | Pneumonia - chemically induced | Bronchi - metabolism | Bronchial Hyperreactivity - metabolism | Female | Bronchi - pathology | Guinea Pigs | Docosahexaenoic Acids - chemistry | Cyclooxygenase 2 - chemistry | Phosphoprotein Phosphatases - antagonists & inhibitors | Bronchial Hyperreactivity - prevention & control | Muscle, Smooth - metabolism | Blotting, Western | Docosahexaenoic Acids - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Bronchial Hyperreactivity - pathology | Animals | Cyclooxygenase 2 - metabolism | Fluorescent Antibody Technique | Lung Neoplasms - surgery | Muscle, Smooth - cytology | Pneumonia - metabolism | Protein Kinase C - pharmacology | Asthma - pathology
Journal Article
Journal Article
PLOS BIOLOGY, ISSN 1545-7885, 02/2012, Volume 10, Issue 2, p. e1001255
Journal Article
Pediatric Pulmonology, ISSN 8755-6863, 09/2016, Volume 51, Issue 9, pp. 950 - 957
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 131, Issue 2, pp. 501 - 511.e1
Background Sphingosine-1-phosphate (S1P), which is produced by 2 sphingosine kinase (SphK) isoenzymes, SphK1 and SphK2, has been implicated in IgE-mediated... 
Allergy and Immunology | airway hyperresponsiveness | asthma | nuclear factor κB | mast cells | sphingosine kinase | Sphingosine-1-phosphate | IMMUNITY | FC-EPSILON-RI | nuclear factor kappa B | FACTOR-KAPPA-B | IMMUNOLOGY | MULTIPLE FEATURES | REGULATES MUCIN PRODUCTION | RESPONSES | CYTOKINE PRODUCTION | ALLERGY | GENE-EXPRESSION | MICE | Tumor Necrosis Factor-alpha - metabolism | Lysophospholipids - metabolism | Asthma - metabolism | Bronchial Hyperreactivity - drug therapy | Humans | Goblet Cells - drug effects | NF-kappa B - metabolism | Amino Alcohols - pharmacology | Interferon-gamma - metabolism | Interleukins - metabolism | Inflammation - metabolism | Inflammation - drug therapy | Methacholine Chloride - pharmacology | Mast Cells - metabolism | Bronchial Hyperreactivity - metabolism | Female | Chemokine CCL2 - metabolism | Hyperplasia - drug therapy | Lung - metabolism | Sphingosine - metabolism | Hyperplasia - metabolism | Asthma - enzymology | Immunoglobulin E - metabolism | Mice, Inbred C57BL | Cells, Cultured | Ovalbumin - pharmacology | Asthma - drug therapy | Goblet Cells - metabolism | Mast Cells - drug effects | Asthma - chemically induced | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Bronchial Hyperreactivity - enzymology | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Bronchial Hyperreactivity - pathology | Sphingosine - analogs & derivatives | Animals | Lung - drug effects | Mice | Bronchoalveolar Lavage Fluid - chemistry | Phosphates | Medical colleges | Isoenzymes | Analysis | Sphingosine | Inflammation | Asthma | Studies | Cytokines | Lungs | Rodents | Kinases | Laboratory animals | Allergies
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 04/2013, Volume 48, Issue 4, pp. 431 - 438
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2002, Volume 169, Issue 9, pp. 5315 - 5321
Journal Article