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Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 3, pp. 769 - 780
Background Inflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD). Mitochondrial oxidative stress... 
Allergy and Immunology | airway hyperresponsiveness | antioxidant | proliferation | MitoQ | inflammation | mitochondria | airway smooth muscle | Ozone | oxidative stress | chronic obstructive pulmonary disease | ASTHMA FEATURES | MECHANISMS | IMMUNOLOGY | FRAGMENTATION | HYPERRESPONSIVENESS | BETA | RESPONSES | ALLERGY | ENERGY-METABOLISM | EXPRESSION | COPD | Respiratory System - pathology | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - pathology | Bronchial Hyperreactivity - genetics | Ubiquinone - pharmacology | Muscle, Smooth - drug effects | Smoking - physiopathology | Organophosphorus Compounds - pharmacology | Myocytes, Smooth Muscle - drug effects | Pneumonia - genetics | Pulmonary Disease, Chronic Obstructive - genetics | Bronchial Hyperreactivity - chemically induced | Signal Transduction | Mitochondria - pathology | Smoking - metabolism | Bronchial Hyperreactivity - pathology | Reactive Oxygen Species - antagonists & inhibitors | Electron Transport Chain Complex Proteins - metabolism | Pulmonary Disease, Chronic Obstructive - chemically induced | Respiratory System - drug effects | Airway Remodeling - genetics | Mice | Oxidative Stress - drug effects | Bronchial Hyperreactivity - drug therapy | Myocytes, Smooth Muscle - pathology | Pneumonia - pathology | Membrane Potential, Mitochondrial - drug effects | Pneumonia - chemically induced | Adult | Female | Pulmonary Disease, Chronic Obstructive - metabolism | Myocytes, Smooth Muscle - metabolism | Ubiquinone - analogs & derivatives | Gene Expression Regulation | Hydrogen Peroxide - pharmacology | Electron Transport Chain Complex Proteins - genetics | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Muscle, Smooth - metabolism | Animals | Pneumonia - drug therapy | Respiratory System - metabolism | Aged | Muscle, Smooth - pathology | Oxidative stress | Care and treatment | Lung diseases, Obstructive | Inflammation | Pharmaceutical industry | Biomedical research | Disease | Laboratories | Mortality | Colleges & universities | Smooth muscle | Mitochondrial DNA | Metabolism | Defects | Antioxidants | Mitochondria | Hospitals | Biopsy | Chronic obstructive pulmonary disease | Apoptosis | Smoking | NO, Nitric oxide | ΔΨm, Mitochondrial membrane potential | ASM, Airway smooth muscle | NAC, N-acetylcysteine | RL, Lung resistance | BAL, Bronchoalveolar lavage | OCR, Oxygen consumption rate | dTPP, Decyltriphenylphosphonium bromide | AHR, Airway hyperresponsiveness | logPC100, Concentration of acetylcholine that increased lung resistance by 100 | GOLD, Global Initiative for Chronic Obstructive Lung Disease | ATP, Adenosine triphosphate | KC, Keratinocyte-derived cytokine | JC-1, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide | COPD, Chronic obstructive pulmonary disease | ROS, Reactive oxygen species | Mechanisms of Allergy and Clinical Immunology
Journal Article
PLOS BIOLOGY, ISSN 1545-7885, 02/2012, Volume 10, Issue 2, p. e1001255
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 03/2011, Volume 300, Issue 3, pp. L414 - L421
Le Cras TD, Acciani TH, Mushaben EM, Kramer EL, Pastura PA, Hardie WD, Korfhagen TR, Sivaprasad U, Ericksen M, Gibson AM, Holtzman MJ, Whitsett JA, Khurana... 
Pulmonary inflammation | Allergic asthma | House dust mite | Airway smooth muscle | Airway hyperresponsiveness | BRONCHIAL EPITHELIUM | airway hyperresponsiveness | PHYSIOLOGY | house dust mite | airway smooth muscle | pulmonary inflammation | FACTOR-ALPHA | TYROSINE KINASE INHIBITORS | SMOOTH-MUSCLE | allergic asthma | INDUCED PULMONARY-FIBROSIS | RESPIRATORY SYSTEM | INFLAMMATION | EPIDERMAL-GROWTH-FACTOR | MUCIN PRODUCTION | CIGARETTE-SMOKE | TRANSGENIC MICE | Asthma - parasitology | Inflammation - pathology | Inflammation - complications | Receptor, Epidermal Growth Factor - metabolism | Bronchial Hyperreactivity - physiopathology | Airway Remodeling - physiology | Bronchial Hyperreactivity - parasitology | Disease Models, Animal | Lung - pathology | Asthma - physiopathology | Signal Transduction | Lung - parasitology | Epithelial Cells - pathology | Lung - physiopathology | Bronchial Hyperreactivity - complications | Pyroglyphidae - physiology | Metaplasia | Bronchial Hyperreactivity - pathology | Animals | Asthma - complications | Epithelial Cells - enzymology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Enzyme Activation | Goblet Cells - pathology | Asthma - pathology | Chronic Disease | Muscle, Smooth - pathology | Physiological aspects | Genetic aspects | Health aspects | Airway (Medicine) | Asthma
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 08/2011, Volume 45, Issue 2, pp. 366 - 375
The effects of a newly synthesized docosahexaenoic acid (DHA) derivative, CRBM-0244, on lung inflammation and airway hyperresponsiveness were determined in an... 
CPI-17 | Inflammation | DHA | Airway hyperresponsiveness | Asthma | airway hyperresponsiveness | ACTIVATION | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN BRONCHI | asthma | NECROSIS-FACTOR-ALPHA | HYPERRESPONSIVENESS | CELL BIOLOGY | inflammation | RESPIRATORY SYSTEM | DAMPENS AIRWAY INFLAMMATION | PPAR-GAMMA | TNF-ALPHA | SMOOTH-MUSCLE CONTRACTION | Asthma - metabolism | Asthma - prevention & control | Calcium - metabolism | Humans | Phosphoprotein Phosphatases - metabolism | Pneumonia - pathology | Pneumonia - prevention & control | Lung Neoplasms - pathology | Male | NF-kappa B - metabolism | Monoglycerides - pharmacology | Bronchi - drug effects | Muscle, Smooth - drug effects | Pneumonia - chemically induced | Bronchi - metabolism | Bronchial Hyperreactivity - metabolism | Female | Bronchi - pathology | Guinea Pigs | Docosahexaenoic Acids - chemistry | Cyclooxygenase 2 - chemistry | Phosphoprotein Phosphatases - antagonists & inhibitors | Bronchial Hyperreactivity - prevention & control | Muscle, Smooth - metabolism | Blotting, Western | Docosahexaenoic Acids - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Bronchial Hyperreactivity - pathology | Animals | Cyclooxygenase 2 - metabolism | Fluorescent Antibody Technique | Lung Neoplasms - surgery | Muscle, Smooth - cytology | Pneumonia - metabolism | Protein Kinase C - pharmacology | Asthma - pathology
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 04/2013, Volume 48, Issue 4, pp. 431 - 438
Journal Article
Trends in Immunology, ISSN 1471-4906, 2011, Volume 32, Issue 9, pp. 402 - 411
House dust mites (HDM; Dermatophagoides sp.) are one of the commonest aeroallergens worldwide and up to 85% of asthmatics are typically HDM allergic.... 
Allergy and Immunology | GROWTH-FACTOR RECEPTOR | STRUCTURAL BIOLOGY | DENDRITIC CELLS | EPITHELIAL-CELLS | INNATE IMMUNE-RESPONSES | IMMUNOTHERAPY | AIRWAY INFLAMMATION | T-CELL | NLRP3 INFLAMMASOME | IMMUNOLOGY | THYMIC STROMAL LYMPHOPOIETIN | Allergens - adverse effects | Immunotherapy - methods | Epithelial Cells - metabolism | Bronchial Hyperreactivity - immunology | Dendritic Cells - immunology | Humans | Adrenal Cortex Hormones - therapeutic use | Bronchi - immunology | Antigens, Dermatophagoides - immunology | Allergens - immunology | Respiratory Mucosa - immunology | Asthma - immunology | Toll-Like Receptors - metabolism | beta-Glucans - immunology | Bronchi - pathology | Dendritic Cells - metabolism | Disease Models, Animal | Spores, Fungal - immunology | Bronchial Hyperreactivity - therapy | Respiratory Mucosa - cytology | Toll-Like Receptors - immunology | Bronchial Hyperreactivity - pathology | Animals | Epithelial Cells - immunology | Asthma - therapy | Mice | Respiratory Mucosa - metabolism | Chitin - immunology | Asthma - pathology | Cytokines - biosynthesis | Adrenal Cortex Hormones - administration & dosage | Pyroglyphidae - immunology | Allergens | Analysis | Asthma | Chitinase | Antigens | Enzymes | Disease | Pathogenesis | Lipids | Smooth muscle | Allergies | Molecular weight | Proteins | Airway management | Proteases | Collagen | Ligands | Chemokines | Immune system | Chronic illnesses
Journal Article