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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 07/2014, Volume 111, Issue 31, pp. 11515 - 11520
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 09/2015, Volume 136, Issue 3, pp. 769 - 780
...). Mitochondrial oxidative stress might be involved in driving the oxidative stress–induced pathology. Objective We sought to determine the effects of oxidative stress... 
Allergy and Immunology | airway hyperresponsiveness | antioxidant | proliferation | MitoQ | inflammation | mitochondria | airway smooth muscle | Ozone | oxidative stress | chronic obstructive pulmonary disease | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Respiratory System - pathology | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - pathology | Bronchial Hyperreactivity - genetics | Ubiquinone - pharmacology | Muscle, Smooth - drug effects | Smoking - physiopathology | Organophosphorus Compounds - pharmacology | Myocytes, Smooth Muscle - drug effects | Pneumonia - genetics | Pulmonary Disease, Chronic Obstructive - genetics | Bronchial Hyperreactivity - chemically induced | Signal Transduction | Mitochondria - pathology | Smoking - metabolism | Bronchial Hyperreactivity - pathology | Reactive Oxygen Species - antagonists & inhibitors | Electron Transport Chain Complex Proteins - metabolism | Pulmonary Disease, Chronic Obstructive - chemically induced | Respiratory System - drug effects | Airway Remodeling - genetics | Mice | Oxidative Stress - drug effects | Bronchial Hyperreactivity - drug therapy | Myocytes, Smooth Muscle - pathology | Pneumonia - pathology | Membrane Potential, Mitochondrial - drug effects | Pneumonia - chemically induced | Adult | Female | Pulmonary Disease, Chronic Obstructive - metabolism | Myocytes, Smooth Muscle - metabolism | Ubiquinone - analogs & derivatives | Gene Expression Regulation | Hydrogen Peroxide - pharmacology | Electron Transport Chain Complex Proteins - genetics | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Muscle, Smooth - metabolism | Animals | Pneumonia - drug therapy | Respiratory System - metabolism | Aged | Muscle, Smooth - pathology | Oxidative stress | Care and treatment | Lung diseases, Obstructive | Inflammation | Pharmaceutical industry | Biomedical research | Disease | Laboratories | Mortality | Colleges & universities | Smooth muscle | Mitochondrial DNA | Metabolism | Defects | Antioxidants | Mitochondria | Hospitals | Biopsy | Chronic obstructive pulmonary disease | Apoptosis | Smoking | Index Medicus | Abridged Index Medicus | NO, Nitric oxide | ΔΨm, Mitochondrial membrane potential | ASM, Airway smooth muscle | NAC, N-acetylcysteine | RL, Lung resistance | BAL, Bronchoalveolar lavage | OCR, Oxygen consumption rate | dTPP, Decyltriphenylphosphonium bromide | AHR, Airway hyperresponsiveness | logPC100, Concentration of acetylcholine that increased lung resistance by 100 | GOLD, Global Initiative for Chronic Obstructive Lung Disease | ATP, Adenosine triphosphate | KC, Keratinocyte-derived cytokine | JC-1, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide | COPD, Chronic obstructive pulmonary disease | ROS, Reactive oxygen species | Mechanisms of Allergy and Clinical Immunology
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e70351 - e70351
.... GSNOR activity has been shown to be elevated in human asthmatic lungs, resulting in diminished S-nitrosothiols and thus contributing to increased airway hyperreactivity... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Allergens | Bronchial Hyperreactivity - immunology | Chemokine CCL11 - biosynthesis | Eosinophils - drug effects | Interleukin-13 - antagonists & inhibitors | Glutathione Reductase - metabolism | Bronchial Hyperreactivity - drug therapy | Humans | Pneumonia - pathology | Male | Th2 Cells - immunology | Alcohol Dehydrogenase | Interleukin-5 - biosynthesis | Eosinophils - immunology | Th2 Cells - drug effects | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Interleukin-13 - biosynthesis | Chemokine CCL11 - antagonists & inhibitors | Interleukin-5 - antagonists & inhibitors | Pneumonia - chemically induced | Pneumonia - immunology | Female | Pyrimidinones - pharmacology | Eosinophils - pathology | Th2 Cells - pathology | Bronchial Hyperreactivity - chemically induced | Ovalbumin | Enzyme Inhibitors - pharmacology | Mice, Transgenic | Administration, Intranasal | Cell Movement - drug effects | Bronchial Hyperreactivity - pathology | Animals | Pneumonia - drug therapy | Benzoates - pharmacology | Mice | Mice, Inbred BALB C | Glutathione Reductase - antagonists & inhibitors | Inflammation | T cells | Analysis | Asthma | Health sciences | Smooth muscle | Mucus | Lymphocytes T | Alcohol dehydrogenase | Eotaxin | Alcohols | Respiratory tract | Interleukin 5 | Lymphocytes | Transgenic animals | Rodents | Respiratory tract diseases | Inhibition | Pharmaceutical sciences | Enzymes | Cytokines | Intracellular levels | Hypersensitivity | Environmental health | Intranasal administration | Interleukin 13 | Inhalation | CD4 antigen | Lungs | Regulation | Laboratory animals | Respiration | Binding sites | Reductase | Index Medicus
Journal Article
Journal of veterinary internal medicine, ISSN 0891-6640, 11/2017, Volume 31, Issue 6, pp. 1877 - 1883
Journal Article
American journal of physiology. Lung cellular and molecular physiology, ISSN 1040-0605, 2013, Volume 304, Issue 8, pp. L519 - L529
Proskocil BJ, Bruun DA, Jacoby DB, van Rooijen N, Lein PJ, Fryer AD. Macrophage TNF-alpha mediates parathion-induced airway hyperreactivity in guinea pigs... 
Parathion | Organophosphorus pesticides | Tumor necrosis factor-a | Alveolar macrophages | Airway Hyperreactivity | Respiratory System | Physiology | Life Sciences & Biomedicine | Science & Technology | Receptor, Muscarinic M2 - agonists | Macrophages, Alveolar - pathology | Bronchial Hyperreactivity - immunology | Clodronic Acid - pharmacology | Apoptosis - drug effects | Parathion - toxicity | Humans | Tumor Necrosis Factor-alpha - genetics | Interleukin-1beta - genetics | RNA, Messenger - metabolism | Bronchial Hyperreactivity - genetics | Etanercept | Interleukin-1beta - metabolism | Tumor Necrosis Factor-alpha - immunology | Immunoglobulin G - pharmacology | Female | Receptor, Muscarinic M2 - antagonists & inhibitors | Interleukin 1 Receptor Antagonist Protein - pharmacology | Macrophages, Alveolar - immunology | Interleukin-1beta - antagonists & inhibitors | Bronchial Hyperreactivity - chemically induced | Guinea Pigs | RNA, Messenger - genetics | Bronchial Hyperreactivity - pathology | Animals | Receptors, Tumor Necrosis Factor | Macrophages, Alveolar - drug effects | Macrophage Activation - drug effects | Insecticides - toxicity | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | organophosphorus pesticides | airway hyperreactivity | parathion | tumor necrosis factor-α | alveolar macrophages
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2002, Volume 169, Issue 9, pp. 5315 - 5321
Journal Article
Respiratory research, ISSN 1465-9921, 02/2007, Volume 8, Issue 1, pp. 16 - 16
... of ramatroban and TM30089 to inhibit asthma-like pathology. Affinity for and antagonistic potency of TM30089 on many mouse receptors including thromboxane A2 receptor mTP... 
Inflammation - pathology | Bronchial Hyperreactivity - immunology | Receptors, Immunologic - antagonists & inhibitors | Inflammation - drug therapy | Bronchial Hyperreactivity - physiopathology | Sensitivity and Specificity | Asthma - immunology | Female | Prostaglandin Antagonists - pharmacology | Bronchoalveolar Lavage Fluid - cytology | Radioligand Assay | Receptors, Prostaglandin - antagonists & inhibitors | Disease Models, Animal | Pulmonary Eosinophilia - immunology | Immunization | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Sulfonamides - pharmacology | Asthma - drug therapy | Pulmonary Eosinophilia - pathology | Animals | Mice | Mice, Inbred BALB C | Carbazoles - pharmacology | In Vitro Techniques | Asthma - pathology | Allergens | Prostaglandins | Inflammation | Histochemistry | Asthma | Index Medicus | Research | Disease Models | Inflammation: pathology | Inbred BALB C | Medical and Health Sciences | Prostaglandin Antagonists: pharmacology | Medicin och hälsovetenskap | Pulmonary Eosinophilia: immunology | Klinisk medicin | Asthma: drug therapy | Receptors | Pulmonary Eosinophilia: pathology | Cultured | Lungmedicin och allergi | Asthma: immunology | Bronchoalveolar Lavage Fluid: cytology | Bronchial Hyperreactivity: immunology | Respiratory Medicine and Allergy | Immunologic: antagonists & inhibitors | Prostaglandin: antagonists & inhibitors | Sulfonamides: pharmacology | Cells | Inflammation: drug therapy | Clinical Medicine | Carbazoles: pharmacology | Bronchial Hyperreactivity: physiopathology | Animal | Asthma: pathology
Journal Article