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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2012, Volume 109, Issue 13, pp. 4910 - 4915
Journal Article
Journal Article
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 03/2016, Volume 140, Issue 3, pp. 212 - 220
Context.-Surgical and pathologic handling of lung physically affects lung tissue. This leads to artifacts that alter the morphologic appearance of pulmonary... 
BRONCHIOLITIS | MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR SPREAD | RESECTION | ADENOCARCINOMA | SURGICAL PATHOLOGY | CLASSIFICATION | PATHOLOGY | HISTOLOGY | EXTRANEOUS TISSUE | INTERNATIONAL-ASSOCIATION | MEDICAL LABORATORY TECHNOLOGY | FLOATERS | Asthma - metabolism | Adenocarcinoma - pathology | Lung Diseases - metabolism | Neoplasm Seeding | Humans | Lung Neoplasms - metabolism | Bronchioles - surgery | Lung Neoplasms - pathology | Lymphedema - diagnosis | Biopsy - adverse effects | Bronchiolitis Obliterans - metabolism | Respiratory Mucosa - pathology | Adenocarcinoma - metabolism | Lung - metabolism | Muscle, Smooth - surgery | Bronchiolitis Obliterans - pathology | Diagnostic Errors - classification | Lymphedema - surgery | Specimen Handling - adverse effects | Asthma - diagnosis | Biomarkers - metabolism | Bronchioles - metabolism | Diagnosis, Differential | Lung - pathology | Respiratory Mucosa - surgery | Lymphedema - pathology | Respiratory Mucosa - blood supply | Lung Diseases - diagnosis | Bronchioles - pathology | Bronchiolitis Obliterans - surgery | Lung Diseases - surgery | Muscle, Smooth - metabolism | Bronchiolitis Obliterans - diagnosis | Artifacts | Adenocarcinoma - diagnosis | Diagnostic Errors - prevention & control | Muscle Contraction | Asthma - surgery | Lung Neoplasms - surgery | Lung Diseases - pathology | Respiratory Mucosa - metabolism | Lung - blood supply | Lung - surgery | Lung Neoplasms - diagnosis | Asthma - pathology | Muscle, Smooth - pathology | Lymphedema - metabolism | Adenocarcinoma - surgery | Asthma
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 03/2013, Volume 48, Issue 3, pp. 288 - 298
The regeneration of alveolar epithelial cells is a critical aspect of alveolar reorganization after lung injury. Although alveolar Type II (AT2) cells have... 
GFP | Differentiation | Alveolar Type II cells | SPC | Epithelial | PROGENITOR CELLS | differentiation | ALVEOLAR EPITHELIAL-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | epithelial | PROLIFERATION | DNA-SYNTHESIS | IDENTIFICATION | BASAL-CELLS | CELL BIOLOGY | AIRWAY | RESPIRATORY SYSTEM | BRONCHIOALVEOLAR STEM-CELLS | alveolar Type II cells | II CELLS | TYPE-2 CELLS | Chromatin - metabolism | Lung Injury - pathology | Epithelial Cells - metabolism | Male | Green Fluorescent Proteins - genetics | Lung - cytology | Cell Differentiation - genetics | Regeneration - genetics | Pulmonary Alveoli - metabolism | Lung Injury - metabolism | Pulmonary Alveoli - cytology | Female | Histocompatibility Antigens Class II - metabolism | Lung - metabolism | Membrane Proteins - metabolism | Cell Growth Processes - genetics | Epithelial Cells - cytology | Fibroblasts - metabolism | Antigens, Differentiation, B-Lymphocyte - genetics | Bronchioles - metabolism | Green Fluorescent Proteins - metabolism | Promoter Regions, Genetic | Gene Expression | Respiratory Mucosa - cytology | Membrane Proteins - genetics | Cells, Cultured | Pulmonary Surfactant-Associated Protein C - metabolism | Gene Expression Profiling - methods | Mice, Transgenic | Lung Injury - genetics | Animals | Alleles | Bronchioles - cytology | Pulmonary Surfactant-Associated Protein C - biosynthesis | Pulmonary Surfactant-Associated Protein C - genetics | Fibroblasts - cytology | Mice | Antigens, Differentiation, B-Lymphocyte - metabolism | Histocompatibility Antigens Class II - genetics | Respiratory Mucosa - metabolism | Chromatin - genetics
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 2017, Volume 313, Issue 1, pp. L80 - L91
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7536, pp. 616 - 620
Journal Article
Cell Reports, ISSN 2211-1247, 03/2016, Volume 14, Issue 10, pp. 2289 - 2300
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2012, Volume 287, Issue 15, pp. 12379 - 12386
Acrolein (Acr), a ubiquitous environmental contaminant, is a human carcinogen. Acr can react with DNA to form mutagenic alpha- and gamma-hydroxy-1, N-2-cyclic... 
INDUCED CELL-DEATH | LUNG-CANCER | APOPTOSIS | OXIDATIVE STRESS | LIPID-PEROXIDATION | MECHANISM | POLYMERASE-ETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | DEOXYGUANOSINE ADDUCT | CHINESE-WOMEN | MutL Protein Homolog 1 | Epithelial Cells - metabolism | Gene Expression - drug effects | Epithelial Cells - drug effects | Humans | DNA Repair Enzymes - genetics | Plasmids - radiation effects | Lung - cytology | DNA Adducts - metabolism | DNA-Binding Proteins - metabolism | Carcinogens - pharmacology | Ultraviolet Rays | Base Sequence | DNA Repair Enzymes - metabolism | Mismatch Repair Endonuclease PMS2 | Nuclear Proteins - genetics | DNA Glycosylases - metabolism | Fibroblasts - metabolism | Acrolein - pharmacology | Mutagens - chemistry | DNA Repair - drug effects | Xeroderma Pigmentosum Group A Protein - metabolism | Respiratory Mucosa - cytology | Oxidation-Reduction | Xeroderma Pigmentosum Group A Protein - genetics | Cells, Cultured | DNA Glycosylases - genetics | Mutagens - pharmacology | Adenosine Triphosphatases - metabolism | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide - chemistry | Fibroblasts - drug effects | Adaptor Proteins, Signal Transducing - genetics | Plasmids - chemistry | Bronchioles - cytology | Adenosine Triphosphatases - genetics | Adaptor Proteins, Signal Transducing - metabolism | DNA Nucleotide Excision Repair | BPDE-DNA Damage | Acrolein | DNA and Chromosomes | Lung Cancer | Mutagenesis | DNA Mismatch Repair | DNA Repair | DNA Damage
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 04/2014, Volume 33, Issue 16, pp. 2134 - 2144
Protein kinase C alpha (PKC alpha) can activate both pro- and anti-tumorigenic signaling depending upon cellular context. Here, we investigated the role of PKC... 
tumor suppressor | bronchio-alveolar stem cells | p38 MAPK | lung adenocarcinoma | Wilm's Tumor 1 gene | inhibitors of DNA Binding (Id) | ONCOGENIC K-RAS | NUDE-MICE | PROMOTING PHORBOL ESTERS | CANCER CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTISENSE OLIGONUCLEOTIDE INHIBITOR | OVARIAN-CARCINOMA | MOUSE MODELS | CELL BIOLOGY | DRUG-INDUCED APOPTOSIS | ONCOLOGY | TRANSFORMED GROWTH | GENETICS & HEREDITY | SMOOTH-MUSCLE-CELLS | Immunohistochemistry | WT1 Proteins - metabolism | Protein Kinase C-alpha - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Lung Neoplasms - metabolism | Protein Kinase C-alpha - genetics | Gene Expression Regulation, Neoplastic | Inhibitor of Differentiation Proteins - genetics | Lung Neoplasms - pathology | Male | Mice, 129 Strain | Stem Cells - metabolism | Pulmonary Alveoli - metabolism | Female | p38 Mitogen-Activated Protein Kinases - metabolism | WT1 Proteins - genetics | Disease Models, Animal | Proto-Oncogene Proteins p21(ras) - metabolism | Lung Neoplasms - genetics | Bronchioles - metabolism | Pulmonary Alveoli - pathology | Mice, Inbred C57BL | Cells, Cultured | p38 Mitogen-Activated Protein Kinases - genetics | Bronchioles - pathology | Inhibitor of Differentiation Proteins - metabolism | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Animals | Transforming Growth Factor beta - genetics | Stem Cells - pathology | Mice | Enzyme Activation | Transforming Growth Factor beta - metabolism | Wilm’s Tumor 1 gene
Journal Article