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1. Full Text Generation and characterization of ALX-0171, a potent novel therapeutic nanobody for the treatment of respiratory syncytial virus infection
by Detalle, Laurent and Stohr, Thomas and Palomo, Concepción and Piedra, Pedro A and Gilbert, Brian E and Mas, Vicente and Millar, Andrena and Power, Ultan F and Stortelers, Catelijne and Allosery, Koen and Melero, José A and Depla, Erik
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 01/2016, Volume 60, Issue 1, pp. 6 - 13
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Palivizumab - pharmacology | Humans | Respiratory Syncytial Viruses - immunology | Male | Antiviral Agents - metabolism | Viral Fusion Proteins - immunology | Respiratory Syncytial Virus Infections - drug therapy | Nasal Cavity - virology | Virus Replication - drug effects | Antiviral Agents - pharmacology | Gene Expression | Respiratory Syncytial Viruses - drug effects | Models, Molecular | Rats | Recombinant Proteins - chemistry | Lung - drug effects | Pichia - genetics | Respiratory Syncytial Virus Infections - pathology | Viral Load - drug effects | Respiratory Syncytial Viruses - pathogenicity | Antibodies, Viral - pharmacology | Viral Fusion Proteins - genetics | Antiviral Agents - immunology | Neutralization Tests | Respiratory Syncytial Virus Infections - immunology | Single-Domain Antibodies - immunology | Antibodies, Neutralizing - immunology | Lung - virology | Pichia - metabolism | Viral Fusion Proteins - chemistry | Female | Nasal Cavity - drug effects | Respiratory Syncytial Virus Infections - virology | Nasal Cavity - immunology | Antibodies, Viral - biosynthesis | Palivizumab - biosynthesis | Administration, Inhalation | Antibodies, Neutralizing - pharmacology | Palivizumab - immunology | Recombinant Proteins - genetics | Single-Domain Antibodies - pharmacology | Sigmodontinae | Animals | Recombinant Proteins - immunology | Antibodies, Neutralizing - biosynthesis | Antibodies, Viral - immunology | Viral Fusion Proteins - antagonists & inhibitors | Single-Domain Antibodies - biosynthesis | Lung - immunology | Index Medicus
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2. Full Text Viral Bronchiolitis in Children
by Meissner, H. Cody
The New England journal of medicine, ISSN 0028-4793, 01/2016, Volume 374, Issue 1, pp. 62 - 72
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Humans | Risk Factors | Child, Preschool | Infant | Bronchiolitis, Viral - virology | Respiratory Sounds - etiology | Respiratory Syncytial Virus Infections - immunology | Respiratory Syncytial Virus Vaccines | Bronchiolitis, Viral - therapy | Asthma - etiology | Respiratory Syncytial Virus Infections - therapy | Bronchiolitis, Viral - complications | Bronchiolitis, Viral - immunology | Pathology | Bronchopneumonia | Respiratory diseases | Childrens health | Viruses | Wheezing | Genetic factors | Children | Children & youth | Index Medicus | Abridged Index Medicus
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3. Full Text Co-immunization with virus-like particle and DNA vaccines induces protection against respiratory syncytial virus infection and bronchiolitis
by Hwang, Hye Suk and Kwon, Young-Man and Lee, Jong Seok and Yoo, Si-Eun and Lee, Yu-Na and Ko, Eun-Ju and Kim, Min-Chul and Cho, Min-Kyoung and Lee, Young-Tae and Jung, Yu-Jin and Lee, Ji-Yun and Li, Jian-Dong and Kang, Sang-Moo
Antiviral research, ISSN 0166-3542, 2014, Volume 110, pp. 115 - 123
DNA vaccine | Histopathology | RSV | RSV VLPs | Protection | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Virology | Antiviral agents | Viral diseases of the respiratory system and ent viral diseases | Infectious diseases | Pharmacology. Drug treatments | Viral diseases | Biological and medical sciences | Medical sciences | Human viral diseases | Chronic obstructive pulmonary disease, asthma | Antibiotics. Antiinfectious agents. Antiparasitic agents | Pneumology | Immunoglobulin G - blood | Respiratory Syncytial Viruses - immunology | Vaccination | Vaccines, DNA - immunology | Bronchiolitis, Viral - virology | Th1 Cells - immunology | Antibodies, Viral - blood | Respiratory Syncytial Virus Infections - immunology | Viral Fusion Proteins - immunology | Spodoptera | Lung - virology | Sf9 Cells | Immunoglobulin G - immunology | Respiratory Syncytial Virus Infections - prevention & control | Bronchiolitis, Viral - prevention & control | Female | Cell Line | Inflammation - immunology | Respiratory Syncytial Virus Vaccines | Animals | Eosinophilia - immunology | Antibodies, Viral - immunology | Vaccines, Virus-Like Particle - immunology | Mice | Mice, Inbred BALB C | Viral Load - drug effects | Antibodies, Neutralizing - blood | Lung - immunology | Bronchiolitis, Viral - immunology | Virus diseases | Respiratory tract diseases | Vaccines | Health aspects | DNA | Prevention | Medical research | Medicine, Experimental | Glycoproteins | Histochemistry | Formaldehyde | Index Medicus | histopathology | protection
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4. Full Text Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion
by Lynch, Jason P and Werder, Rhiannon B and Loh, Zhixuan and Sikder, Md. Al Amin and Curren, Bodie and Zhang, Vivian and Rogers, Matthew J and Lane, Katie and Simpson, Jennifer and Mazzone, Stuart B and Spann, Kirsten and Hayball, John and Diener, Kerrilyn and Everard, Mark L and Blyth, Christopher C and Forstner, Christian and Dennis, Paul G and Murtaza, Nida and Morrison, Mark and Cuív, Páraic Ó and Zhang, Ping and Haque, Ashraful and Hill, Geoffrey R and Sly, Peter D and Upham, John W and Phipps, Simon
The Journal of experimental medicine, ISSN 0022-1007, 02/2018, Volume 215, Issue 2, pp. 537 - 557
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Semaphorins - antagonists & inhibitors | Asthma - prevention & control | Dendritic Cells - immunology | Humans | Child, Preschool | Male | Respiratory Syncytial Virus Infections - immunology | Fatty Acids, Volatile - metabolism | Receptor, Interferon alpha-beta - antagonists & inhibitors | T-Lymphocytes, Regulatory - immunology | Fatty Acids, Volatile - immunology | Asthma - immunology | T-Lymphocytes, Regulatory - cytology | Bronchiolitis, Viral - prevention & control | Female | Semaphorins - immunology | Child | Respiratory Syncytial Virus Infections - complications | Disease Models, Animal | Animals, Newborn | Microbiota - immunology | Mice, Inbred C57BL | Mice, Transgenic | Animals | Receptor, Interferon alpha-beta - immunology | Bronchiolitis, Viral - etiology | Interleukin-10 - biosynthesis | Mice | Bronchiolitis, Viral - immunology | Neonates | Dendritic cells | Bronchopneumonia | Propionic acid | Microbiomes | Neuropilin | Viruses | Risk factors | Asthma | Interleukin 6 | Microorganisms | Depletion | Antibiotics | Interferon | Children | Expansion | Colonization | Age | Index Medicus | 311 | 319
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5. Full Text Role of viral infections in the development and exacerbation of asthma in children
by Jartti, Tuomas and Gern, James E
Journal of allergy and clinical immunology, ISSN 0091-6749, 10/2017, Volume 140, Issue 4, pp. 895 - 906
wheeze | wheezing | respiratory syncytial virus | rhinovirus | virus | bronchiolitis | Asthma | child | exacerbation | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Microbiota - immunology | Virus Diseases - immunology | Humans | Palivizumab - therapeutic use | Respiratory Syncytial Viruses - immunology | Virulence | Rhinovirus - pathogenicity | Risk | Asthma - drug therapy | Disease Progression | Bronchiolitis | Animals | Virus Diseases - drug therapy | Asthma - immunology | Anti-Inflammatory Agents - therapeutic use | Respiratory Sounds | Rhinovirus - immunology | Child | Respiratory Syncytial Viruses - pathogenicity | Development and progression | Virulence (Microbiology) | Asthma in children | Risk factors | Medical colleges | Nerve growth factor | Epstein-Barr virus | Bronchopneumonia | Wheezing | Viruses | Infections | Vaccines | Respiratory tract | Copyright | Airway management | Illnesses | Vitamin D | Virulence factors | Genetics | Accreditation | Children | Age | Hypersensitivity | Inflammation | Environmental factors | Risk analysis | Health education | Allergies | Structural damage | Monoclonal antibodies | Nitrogen dioxide | Viral infections | Index Medicus | Abridged Index Medicus | RV, Rhinovirus | TLR, Toll-like receptor | nBreg, Neonatal regulatory B | OR, Odds ratio | CDHR3, Cadherin-related family member 3 | NGF, Nerve growth factor | RSV, Respiratory syncytial virus
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6. Full Text Neutrophil infiltration and activation in bronchiolitic airways are independent of viral etiology
by Cavallaro, Elena C and Liang, Kar‐Kate and Lawrence, Mark D and Forsyth, Kevin D and Dixon, Dani‐Louise
Pediatric pulmonology, ISSN 8755-6863, 02/2017, Volume 52, Issue 2, pp. 238 - 246
chemokine | viral etiology | nasopharyngeal aspirate | neutrophil | bronchiolitis | Respiratory System | Pediatrics | Life Sciences & Biomedicine | Science & Technology | Immunoassay | Adenoviridae Infections - virology | Coinfection | Humans | Breast Feeding | Infant | Male | Bronchiolitis, Viral - virology | Bronchiolitis - immunology | Metapneumovirus - genetics | Respiratory Syncytial Virus Infections - immunology | Picornaviridae Infections - virology | Paramyxoviridae Infections - virology | Nasopharynx - virology | Polymerase Chain Reaction | Adenoviridae - genetics | Female | Respiratory Sounds | Respiratory Syncytial Virus Infections - virology | Neutrophil Infiltration - immunology | Severity of Illness Index | Peroxidase - immunology | Picornaviridae Infections - immunology | Inflammation - virology | Neutrophils - immunology | Adenoviridae Infections - immunology | Inflammation - immunology | Paramyxoviridae Infections - immunology | Nasopharynx - immunology | Respiratory Syncytial Viruses - genetics | Interleukin-6 - immunology | Interleukin-8 - immunology | Rhinovirus - genetics | Bronchiolitis, Viral - immunology | Index Medicus
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7. Full Text LAIR-1 limits neutrophil extracellular trap formation in viral bronchiolitis
by Geerdink, Ruben J and Hennus, Marije P and Westerlaken, Geertje H.A and Abrahams, Alferso C and Albers, Kim I and Walk, Jona and Wesselink, Esther and Janssen, Riny and Bont, Louis and Meyaard, Linde
Journal of allergy and clinical immunology, ISSN 0091-6749, 02/2018, Volume 141, Issue 2, pp. 811 - 814
Immunology and Allergy | Immunology | Allergy | Life Sciences & Biomedicine | Science & Technology | Extracellular Traps - immunology | Bronchiolitis, Viral - pathology | Humans | Respiratory Syncytial Viruses - immunology | Neutrophils - immunology | Female | Male | Receptors, Immunologic - immunology | Respiratory Syncytial Virus Infections - pathology | Respiratory Syncytial Virus Infections - immunology | Bronchiolitis, Viral - immunology | Neutrophils - pathology | Signs and symptoms | Bronchopneumonia | Neutrophils | Gram-positive bacteria | Antibodies | Patients | Streptococcus infections | Proteins | Airway management | Respiratory syncytial virus | Microscopy | Influenza | Sepsis | Viral infections | Index Medicus | Abridged Index Medicus
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8. Full Text Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection
by Loebbermann, J and Thornton, H and Durant, L and Sparwasser, T and Webster, K.E and Sprent, J and Culley, F.J and Johansson, C and Openshaw, P.J
Mucosal immunology, ISSN 1933-0219, 03/2012, Volume 5, Issue 2, pp. 161 - 172
Life Sciences & Biomedicine | Immunology | Science & Technology | T-Lymphocytes, Regulatory - metabolism | Antibodies - metabolism | Granzymes - metabolism | Humans | Respiratory Syncytial Viruses - immunology | Granzymes - genetics | Lymphocyte Depletion | Respiratory Syncytial Virus Infections - immunology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Lung - virology | Interleukin-2 - immunology | Bronchiolitis, Viral - prevention & control | Granzymes - immunology | Child | Respiratory Syncytial Virus Infections - complications | Disease Models, Animal | Interleukin-2 - metabolism | Acute Disease | Lung - pathology | Cells, Cultured | Pneumonia, Viral - immunology | Viral Load - immunology | Disease Progression | Cell Movement - drug effects | T-Lymphocytes, Regulatory - drug effects | Animals | Bronchiolitis, Viral - etiology | Mice | Respiratory Syncytial Virus Infections - therapy | Antigen-Antibody Complex - administration & dosage | Viral Load - drug effects | Lung - immunology | Respiratory Syncytial Viruses - pathogenicity | Bronchiolitis, Viral - immunology | T-Lymphocytes, Regulatory - virology | Index Medicus
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