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Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7681, pp. 525 - 528
The peptide-loading complex (PLC) is a transient, multisubunit membrane complex in the endoplasmic reticulum that is essential for establishing a hierarchical... 
VISUALIZATION | TAP | TRANSPORTERS | TAPASIN | CALRETICULIN | MULTIDISCIPLINARY SCIENCES | MOLECULAR ARCHITECTURE | ERP57 | PURIFICATION | MAJOR HISTOCOMPATIBILITY COMPLEX | BINDING | ATP Binding Cassette Transporter, Subfamily B, Member 2 - chemistry | Protein Disulfide-Isomerases - metabolism | Protein Disulfide-Isomerases - ultrastructure | ATP Binding Cassette Transporter, Subfamily B, Member 3 - chemistry | Cytosol - immunology | Humans | Endoplasmic Reticulum - metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 2 - ultrastructure | Histocompatibility Antigens Class I - metabolism | Multiprotein Complexes - metabolism | Endoplasmic Reticulum - chemistry | Antigen Presentation | ATP Binding Cassette Transporter, Subfamily B, Member 3 - ultrastructure | Calreticulin - metabolism | Protein Domains | Membrane Transport Proteins - metabolism | Binding Sites | Histocompatibility Antigens Class I - immunology | Models, Molecular | Histocompatibility Antigens Class I - chemistry | Burkitt Lymphoma - chemistry | Disease Progression | Membrane Transport Proteins - chemistry | Calreticulin - chemistry | Calreticulin - ultrastructure | Cryoelectron Microscopy | Multiprotein Complexes - ultrastructure | Multiprotein Complexes - chemistry | ATP Binding Cassette Transporter, Subfamily B, Member 3 - metabolism | Histocompatibility Antigens Class I - ultrastructure | Membrane Transport Proteins - ultrastructure | Models, Biological | ATP Binding Cassette Transporter, Subfamily B, Member 2 - metabolism | Cytosol - metabolism | Protein Disulfide-Isomerases - chemistry | Multiprotein Complexes - immunology | Peptides | Physiological aspects | Major histocompatibility complex | Oxidoreductase | Antigen processing | Lymphocytes T | Cell surface | Proteins | Calreticulin | Immune system | Binding | Symbiosis | Translocation | Antigens | Immune response | Macromolecules | TAP protein | Lymphoma | Glycan | Burkitt's lymphoma | Tapasin | Microscopy | Lymphomas | Endoplasmic reticulum | Histocompatibility | ABC transporter
Journal Article
Cancer, ISSN 0008-543X, 10/2017, Volume 123, Issue 19, pp. 3807 - 3815
BACKGROUND Programmed death 1 (PD‐1) signaling in the tumor microenvironment dampens immune responses to cancer, and blocking this axis induces antitumor... 
checkpoint | neuroblastoma | tumor‐infiltrating lymphocytes | programmed death 1/programmed death 1 ligand (PD‐1/PD‐L1) blockade | immunotherapy | pediatric cancer | tumor-infiltrating lymphocytes | programmed death 1/programmed death 1 ligand (PD-1/PD-L1) blockade | ONCOLOGY-GROUP | PD-L1 EXPRESSION | INFILTRATING LYMPHOCYTES | WILMS-TUMOR | UNTREATED MELANOMA | LUNG-CANCER | ONCOLOGY | NEUROECTODERMAL TUMOR | ADULT GLIOBLASTOMA | T-CELLS | CLINICAL-SIGNIFICANCE | Immunohistochemistry | Bone Neoplasms - mortality | Tissue Array Analysis | Humans | Sarcoma, Ewing - pathology | Rhabdomyosarcoma - pathology | Neuroblastoma - mortality | Osteosarcoma - chemistry | Macrophages | Bone Neoplasms - pathology | Burkitt Lymphoma - pathology | Neoplasms - chemistry | Lymphocytes, Tumor-Infiltrating | Burkitt Lymphoma - immunology | Neuroblastoma - immunology | Bone Neoplasms - chemistry | Glioblastoma - chemistry | Child | Neuroblastoma - pathology | Rhabdomyosarcoma - immunology | Sarcoma, Ewing - chemistry | Neuroblastoma - chemistry | Neoplasms - mortality | Bone Neoplasms - immunology | Burkitt Lymphoma - chemistry | Sarcoma, Ewing - immunology | Osteosarcoma - immunology | Glioblastoma - immunology | Neoplasms - immunology | Glioblastoma - pathology | Neoplasm Proteins - analysis | B7-H1 Antigen - analysis | Rhabdomyosarcoma - chemistry | Neoplasms - pathology | Osteosarcoma - pathology | Chemotherapy | Usage | Care and treatment | Diagnosis | Research | Gene expression | Cancer in children | Cancer | Pediatrics | Parkinson's disease | PD-1 protein | Glioblastoma | Neuroblastoma | Tissues | Anticancer properties | Metastases | Lymphocytes | Children | Movement disorders | Immune system | Immune response | Neurodegenerative diseases | Tumor cells | Mortality | Patients | Survival | Glioblastoma multiforme | Lymphoma | Burkitt's lymphoma | PD-L1 protein | Biomarkers | Ligands | Death | Antitumor activity | Infiltration | Lymphomas | Diagnostic systems | Tumors | Apoptosis
Journal Article
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10036, pp. 2402 - 2411
Summary Background Short intensive chemotherapy is the standard of care for adult patients with Burkitt's leukaemia or lymphoma. Findings from single-arm... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | CODOX-M/IVAC | CLEAVED-CELL LYMPHOMA | ACUTE-LYMPHOBLASTIC-LEUKEMIA | MULTIAGENT CHEMOTHERAPY | ADOLESCENTS | PLUS RITUXIMAB | NON-HODGKIN-LYMPHOMA | SURVIVAL RATE | PEDIATRIC-ONCOLOGY-SOCIETY | CHILDREN | Cyclophosphamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Injections, Intravenous | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Patient Selection | Burkitt Lymphoma - pathology | Hydrocortisone - administration & dosage | Vincristine - administration & dosage | Adult | Female | France | Odds Ratio | Burkitt Lymphoma - drug therapy | Doxorubicin - administration & dosage | Prednisone - administration & dosage | Drug Administration Schedule | Biomarkers, Tumor - analysis | Proportional Hazards Models | Treatment Outcome | Burkitt Lymphoma - diagnosis | Burkitt Lymphoma - chemistry | Cytarabine - administration & dosage | Rituximab - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Methotrexate - administration & dosage | Aged | Bone Marrow Neoplasms - drug therapy | Neoplasm Staging | Central Nervous System Neoplasms - drug therapy | Methylprednisolone - administration & dosage | Chemotherapy | Leukemia | Lymphomas | Adults | Epidemiology | Biometry | Cancer | Survival analysis | Biomedical research | Dehydrogenases | Medical prognosis | Clinical trials
Journal Article
Journal Article
Journal of Clinical Pathology, ISSN 0021-9746, 03/2016, Volume 69, Issue 3, pp. 266 - 270
Journal Article
Journal Article
Journal Article
Cancer, ISSN 0008-543X, 10/2012, Volume 118, Issue 19, pp. 4715 - 4724
Journal Article
Journal Article
Journal Article