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Addiction Biology, ISSN 1355-6215, 07/2015, Volume 20, Issue 4, pp. 676 - 689
Converging evidence indicates that epigenetic mechanisms are involved in drug addiction, and that enzymes involved in chromatin remodeling may represent... 
alcohol | sodium butyrate | Addiction | relapse | operant self‐administration | HDAC inhibitor | epigenetics | histone acetylation | operant self-administration | INTERMITTENT EXPOSURE | WISTAR RATS | ACETYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | COCAINE | SUBSTANCE ABUSE | MODEL | INDUCED BEHAVIORAL SENSITIZATION | GENE-EXPRESSION | ALCOHOL DEPENDENCE | BRAIN | AMYGDALA | Recurrence | Rats, Wistar | Rats, Long-Evans | Histone Deacetylase Inhibitors - administration & dosage | Injections, Intraventricular | Ethanol - administration & dosage | Male | Alcoholism - prevention & control | Benzamides - administration & dosage | Self Administration | Benzamides - pharmacology | Butyric Acid - pharmacology | Epigenesis, Genetic - drug effects | Acetylation | Sucrose - administration & dosage | Pyridines - administration & dosage | Injections, Intraperitoneal | Butyric Acid - administration & dosage | Rats, Sprague-Dawley | Animals | Analysis of Variance | Central Nervous System Depressants - administration & dosage | Alcoholism - genetics | Conditioning, Operant | Histone Deacetylase Inhibitors - pharmacology | Pyridines - pharmacology | Histones - metabolism | Sweetening Agents - administration & dosage | Prevention | Epigenetic inheritance | Alcohol, Denatured | Alcoholism | Alcoholics | Alcohol | Esters | Epigenetics | Chromatin | Substance abuse treatment | Addictions
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 09/2017, Volume 262, pp. 273 - 283
Journal Article
AAPS PharmSciTech, ISSN 1530-9932, 4/2016, Volume 17, Issue 2, pp. 294 - 306
This study was conducted to develop formulations of hydrocortisone butyrate (HB)-loaded poly(d,l-lactic-co-glycolic acid) nanoparticles (PLGA NP) suspended in... 
Biochemistry, general | Biotechnology | thermosensitive gel | Biomedicine | topical administration | Pharmacy | hydrocortisone butyrate | Pharmacology/Toxicology | PLGA nanoparticles | BLOCK-COPOLYMERS | DEPENDENT CELLULAR UPTAKE | DRUG-DELIVERY SYSTEM | SIZE | BIODEGRADABLE NANOPARTICLES | SOLID LIPID NANOPARTICLES | ATOPIC-DERMATITIS | RECEPTOR-MEDIATED ENDOCYTOSIS | POLYMERIC NANOPARTICLES | SILICA NANOPARTICLES | PHARMACOLOGY & PHARMACY | Administration, Ophthalmic | Polyvinyl Alcohol - chemistry | Nanoparticles - chemistry | Humans | Biological Availability | Delayed-Action Preparations - chemistry | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Hydrocortisone - analogs & derivatives | Hydrocortisone - administration & dosage | Hydrocortisone - chemistry | Ocular Absorption | Emulsions - administration & dosage | Gels - chemistry | Poloxamer - chemistry | Cell Line | Emulsions - chemistry | Gels - administration & dosage | Corneal Keratocytes - drug effects | Chemistry, Pharmaceutical | Particle Size | Chitosan - chemistry | Eye Diseases - drug therapy | Nanoparticles - administration & dosage | Administration, Topical | Drug Delivery Systems - methods | Drugs | Drug delivery systems | Surface active agents | Esters | Ophthalmology | Hydrocortisone | Organic acids | Vehicles
Journal Article
Psychopharmacology, ISSN 0033-3158, 1/2019, Volume 236, Issue 1, pp. 517 - 529
A challenge in treating substance use disorder is that successful treatment often does not persist, resulting in relapse and continued drug seeking. One... 
Neurosciences | Biomedicine | Extinction | Epigenetics | Long-Evans rats | Histone acetylation | Intravenous cocaine | Pharmacology/Toxicology | Psychiatry | POSTTRAUMATIC-STRESS-DISORDER | LONG-TERM-MEMORY | PSYCHIATRY | BASOLATERAL AMYGDALA | DRUG-SEEKING | GENE PROMOTERS | NEUROSCIENCES | NEGATIVE REGULATOR | DORSAL HIPPOCAMPUS | SODIUM-BUTYRATE | MEDIAL PREFRONTAL CORTEX | SEEKING BEHAVIOR | PHARMACOLOGY & PHARMACY | Cues | Recurrence | Drug-Seeking Behavior - physiology | Rats, Long-Evans | Reinforcement (Psychology) | Conditioning, Operant - physiology | Extinction, Psychological - drug effects | Rats | Male | Cocaine-Related Disorders - physiopathology | Association Learning - physiology | Drug-Seeking Behavior - drug effects | Association Learning - drug effects | Cocaine - administration & dosage | Self Administration | Animals | Conditioning, Operant - drug effects | Histone Deacetylase Inhibitors - pharmacology | Phenylenediamines - pharmacology | Histone Deacetylases - physiology | Acrylamides - pharmacology | Extinction, Psychological - physiology | Extinction (Psychology) | Physiological aspects | Cocaine abuse | Enzyme inhibitors | Histone deacetylase | Drug delivery systems | Operant conditioning | Intravenous administration | Delivery scheduling | Pharmacology | Injection | Substance use | Drug self-administration | Inhibitors | Motivation | Reinstatement | Cocaine | extinction | Long Evans rats | intravenous cocaine | histone acetylation | epigenetics
Journal Article
Journal Article