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1. Full Text The Renaissance of α‐Methylene‐γ‐butyrolactones: New Synthetic Approaches
by Kitson, Russell R. A and Millemaggi, Alessia and Taylor, Richard J. K
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2009, Volume 48, Issue 50, pp. 9426 - 9451
The amount of research activity concerning α‐methylene‐γ‐butyrolactones and α‐alkylidene‐γ‐butyrolactones has increased dramatically in recent years. This... 
natural products | bioactivity | α‐alkylidene‐γ‐butyrolactones | α‐methylene‐γ‐butyrolactones | biosynthesis | α-alkylidene-γ- butyrolactones | Bioactivity | Biosynthesis | Natural products | α-methylene-γ-butyrolactones | CROSS-METATHESIS | DREIDING-SCHMIDT REACTIONS | CATALYZED STEREOSELECTIVE-SYNTHESIS | HIGHLY OXYGENATED 1,10-SECO-EUDESMANOLIDES | BIOLOGICAL-ACTIVITIES | CYTOTOXIC ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | SESQUITERPENE LACTONES | a-alkylidene-gamma-butyrolactones | CORAL LOBOPHYTUM-CRASSUM | AERIAL PARTS | alpha-methylene-gamma-butyrolactones | ENANTIOSELECTIVE TOTAL-SYNTHESIS | 4-Butyrolactone - therapeutic use | 4-Butyrolactone - biosynthesis | 4-Butyrolactone - chemical synthesis | Molecular Structure | Structure-Activity Relationship | 4-Butyrolactone - analogs & derivatives | Drug Evaluation, Preclinical
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2. Full Text Aluminum salen and salan complexes in the ring‐opening polymerization of cyclic esters: Controlled immortal and copolymerization of rac‐β‐butyrolactone and rac‐lactide
by Cross, Edward D and Allan, Laura E. N and Decken, Andreas and Shaver, Michael P
Journal of Polymer Science Part A: Polymer Chemistry, ISSN 0887-624X, 03/2013, Volume 51, Issue 5, pp. 1137 - 1146
Aluminum‐based salen and salan complexes mediate the ring‐opening polymerization (ROP) of rac‐β‐butyrolactone (β‐BL), rac‐lactide, and ε‐caprolactone. Al‐salen... 
copolymerization | ring‐opening polymerization | rac‐lactide | biodegradable | rac‐β‐butyrolactone | rac-β-butyrolactone | rac-lactide | ring-opening polymerization | rac-ss-butyrolactone | POLYMER SCIENCE | ACID | PREDOMINANTLY SYNDIOTACTIC POLY(BETA-HYDROXYBUTYRATE) | BETA-D,L-BUTYROLACTONE | RACEMIC LACTIDE | STEREOELECTIVE POLYMERIZATION | EPSILON-CAPROLACTONE | LACTONES | BIODEGRADABLE ALIPHATIC POLYESTERS | CHAIN-END CONTROL | METAL-COMPLEXES
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3. Full Text Chemoselective Lewis pair polymerization of renewable Multivinyl-functionalized γ-butyrolactones
by Gowda, Ravikumar R and Chen, Eugene Y.-X
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, ISSN 1364-503X, 08/2017, Volume 375, Issue 2101, p. 20170003
Multivinyl-functionalized gamma-butyrolactones, gamma-vinyl-gamma-methyl-alpha-methylene-gamma-butyrolactone (gamma VMMBL) and... 
Lewis pair polymerization | γ-vinyl-γ-methyl-α-methylene-γ-butyrolactone | γ-allyl-γ-methyl-α-methylene-γ-butyrolactone | PROTON-TRANSFER POLYMERIZATION | ORGANOCATALYTIC LIVING POLYMERIZATION | COORDINATION POLYMERIZATION | CONJUGATE-ADDITION | METHYL-METHACRYLATE | MULTIDISCIPLINARY SCIENCES | N-HETEROCYCLIC CARBENES | TRANSFER RADICAL POLYMERIZATION | gamma-allyl-gamma-methyl-alpha-methylene-gamma-butyrolactone | ALLYL METHACRYLATE | gamma-vinyl-gamma-methyl-alpha-methylene-gamma-butyrolactone | VINYL METHACRYLATE | RING-OPENING POLYMERIZATION | 143 | 1002 | 117 | 108 | 142
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4. Ring-opening polymerization of γ-butyrolactone and its derivatives: A review
by Danko, Martin and Mosnázek, Jaroslav
Polimery/Polymers, ISSN 0032-2725, 2017, Volume 62, Issue 4, pp. 272 - 282
gamma-Butyrolactone (gamma-BL) derivatives are reviewed from the point of view of their ability to form polymers by ring-opening polymerization. The... 
Thermodynamic limitations | Ring-opening polymerization | γ-butyrolactone derivatives | Homopolymerization of γ-butyrolactone | γ-butyrolactone | POLYMERS | POLYMER SCIENCE | ACID | gamma-butyrolactone derivatives | MONOMER | thermodynamic limitations | POLYESTER | homopolymerization of gamma-butyrolactone | ring-opening polymerization | LACTONES | gamma-butyrolactone | INHIBITORS | COPOLYMERIZATION
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5. Full Text Effects of Chain Ends on Thermal and Mechanical Properties and Recyclability of Poly(γ‐butyrolactone)
by Tang, Jing and Chen, Eugene Y.‐X
Journal of Polymer Science Part A: Polymer Chemistry, ISSN 0887-624X, 10/2018, Volume 56, Issue 20, pp. 2271 - 2279
ABSTRACT This work investigates effects of poly(γ‐butyrolactone) (PγBL) with different initiation and termination chain ends on five types of materials... 
thermal stability | hydrolytic degradation | poly(γ‐butyrolactone) | post‐functionalization | post-functionalization | poly(γ-butyrolactone) | POLYMER SCIENCE | PROTECTION | COPOLYESTERS | poly(-butyrolactone) | ALIPHATIC POLYESTER | LIGANDS | CHEMISTRY | LACTIDE | RECENT PROGRESS | RING-OPENING POLYMERIZATION | CYCLIC POLYMERS | METAL-COMPLEXES | Mechanical properties | Polymers | Lactones | Degradation | Capping | Chain dynamics | Recyclability | Butyrolactone | Dynamic stability | Thermodynamic properties | Chemical synthesis | Thermal stability | Material properties
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6. Full Text Differential contributions of two SARP family regulatory genes to indigoidine biosynthesis in Streptomyces lavendulae FRI-5
by Kurniawan, Yohanes Novi and Kitani, Shigeru and Maeda, Asa and Nihira, Takuya
Applied Microbiology and Biotechnology, ISSN 0175-7598, 12/2014, Volume 98, Issue 23, pp. 9713 - 9721
The Streptomyces antibiotic regulatory protein (SARP) family regulators have been shown to control the production of secondary metabolites in many Streptomyces... 
Life Sciences | Biotechnology | γ-Butyrolactone autoregulator | Microbiology | Microbial Genetics and Genomics | Streptomyces | Secondary metabolism | Indigoidine | CONJUGAL TRANSFER | VIRGINIAMYCIN PRODUCTION | ESCHERICHIA-COLI | BUTYROLACTONE AUTOREGULATOR | ANTIBIOTIC PRODUCTION | TRANSCRIPTIONAL REGULATOR | gamma-Butyrolactone autoregulator | BLUE PIGMENT PRODUCTION | GAMMA-BUTYROLACTONE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | COELICOLOR A3 | Streptomyces - genetics | Repressor Proteins - genetics | Gene Expression Profiling | Transcription Factors - genetics | Pigments, Biological - metabolism | Streptomyces - metabolism | Transcription Factors - metabolism | Biosynthetic Pathways - genetics | Genes, Regulator | Transcription, Genetic | Piperidones - metabolism | Gene Expression Regulation, Bacterial | Repressor Proteins - metabolism | Antibiotics | Bacterial proteins | Physiological aspects | Genetic aspects | Research | Gene expression | Studies | Metabolites | Analysis | Bacteria | Antimicrobial agents | Biosynthesis | Metabolism
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7. Replacing GHB with GBL in recreational settings: A new trend in chemsex
by Busardò, Francesco Paolo and Gottardi, Massimo and Tini, Anastasio and Minutillo, Adele and Sirignano, Ascanio and Marinelli, Enrico and Zaami, Simona
Current Drug Metabolism, ISSN 1389-2002, 2018, Volume 19, Issue 13, pp. 1080 - 1085
Background: Recently, Gamma-hydroxybutyrate (GHB) consumption in the recreational setting has been replaced by that of its prodrug Gamma-butyrolactone (GBL),... 
γ-hydroxybutyrate (GHB) | γ-butyrolactone (GBL) | Abuse | Chemsex | Liquid G | Dependence | liquid G | gamma-hydroxybutyrate (GHB) | abuse | BIOCHEMISTRY & MOLECULAR BIOLOGY | BUTYROLACTONE GBL | 1,4-BUTANEDIOL | gamma-butyrolactone (GBL) | INTOXICATION | GABA(B) | dependence | PHARMACOLOGY & PHARMACY | chemsex | WITHDRAWAL | PRECURSORS | GAMMA-HYDROXYBUTYRATE GHB | Drug abuse | Toxicity | Oral administration | Central nervous system | Health risks | Mass spectroscopy | Pharmacology | Industrial applications | Liquid chromatography | Bioavailability | High-performance liquid chromatography | Toxicology | Liability | Laws | Rodents | Butyrolactone | g-Hydroxybutyric acid | Mass spectrometry | Public health | Lipophilicity | High performance liquid chromatography | Acute toxicity
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8. Full Text Efficient zinc initiators supported by NNO‐tridentate ketiminate ligands for cyclic esters polymerization
by Chuang, Hui‐Ju and Chen, Hsiao‐Li and Huang, Bor‐Hunn and Tsai, Tsung‐En and Huang, Pei‐Ling and Liao, Tzu‐Ting and Lin, Chu‐Chieh
Journal of Polymer Science Part A: Polymer Chemistry, ISSN 0887-624X, 03/2013, Volume 51, Issue 5, pp. 1185 - 1196
A series of zinc benzylalkoxide complexes, [LnZn(μ‐OBn)]2 (L = L1H–L5H), supported by NNO‐tridentate ketiminate ligands with various electron... 
ε‐decalactone | L‐lactide | β‐butyrolactone | polyethers | catalysts | ε‐caprolactone | ring‐opening polymerization (ROP) | zinc | ε-decalactone | ε-caprolactone | ring-opening polymerization (ROP) | β-butyrolactone | L -lactide | POLYMER SCIENCE | STEREOSELECTIVE POLYMERIZATION | ALUMINUM COMPLEXES | e-caprolactone | STRUCTURAL-CHARACTERIZATION | RAC-LACTIDE | e-decalactone | ss-butyrolactone | RACEMIC LACTIDE | EPSILON-CAPROLACTONE | L-lactide | RING-OPENING POLYMERIZATION | SCHIFF-BASE LIGANDS | METAL-COMPLEXES | Polymerization | Polyols | Ligands | Zinc
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9. Full Text Syntheses of cytotoxic novel arctigenin derivatives bearing halogen and alkyl groups on aromatic rings
by Yamauchi, Satoshi and Wukirsari, Tuti and Ochi, Yoshiaki and Nishiwaki, Hisashi and Nishi, Kosuke and Sugahara, Takuya and Akiyama, Koichi and Kishida, Taro
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2017, Volume 27, Issue 17, pp. 4199 - 4203
The new lignano-9,9′-lactones (α,β-dibenzyl-γ-butyrolactone lignans), which showed the higher cytotoxicity than arctigenin, were synthesized. The well-known... 
Arctigenin | Lignano-9,9′-lactone | Lignan | α,β-Dibenzyl-γ-butyrolactone | γ-Butyrolactone | Matairesinol | Lignano-9,9 '-lactone | CELLS | APOPTOSIS | LIGNAN LACTONES | CHEMISTRY, MEDICINAL | ASYMMETRIC-SYNTHESIS | NATURAL-PRODUCTS | CHEMISTRY, ORGANIC | (-)-MATAIRESINOL | INDUCTION | (-)-ARCTIGENIN | REARRANGEMENT | alpha,beta-Dibenzyl-gamma-butyrolactone | gamma-Butyrolactone | Hydrocarbons, Aromatic - pharmacology | Lignans - chemistry | Antineoplastic Agents - chemical synthesis | Furans - pharmacology | Humans | Molecular Conformation | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Lignans - pharmacology | Dose-Response Relationship, Drug | Hydrocarbons, Aromatic - chemistry | Halogens - pharmacology | Furans - chemistry | HL-60 Cells | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Halogens - chemistry | Lignans - chemical synthesis | Furans - chemical synthesis | HeLa Cells | Drug Screening Assays, Antitumor | Epoxy resins | Resveratrol
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10. Full Text Tulips: A Renewable Source of Monomer for Superabsorbent Hydrogels
by Kollár, Jozef and Mrlík, Miroslav and Moravčíková, Daniela and Kroneková, Zuzana and Liptaj, Tibor and Lacík, Igor and Mosnáček, Jaroslav
Macromolecules, ISSN 0024-9297, 06/2016, Volume 49, Issue 11, pp. 4047 - 4056
A new class of superabsorbent hydrogels was synthesized by copolymerization of acrylamide with sodium 4-hydroxy-2-methylene­butanoate (SHMB). SHMB is obtained... 
PROPAGATION RATE COEFFICIENTS | RESOURCES | IONIZED ACRYLIC-ACID | POLYMER SCIENCE | METHYLENE-GAMMA-BUTYROLACTONE | POLY(ALPHA-METHYLENE-GAMMA-BUTYROLACTONE) | KINETICS | POLYMERIZATION | RADICAL COPOLYMERIZATION | METHACRYLATE | AQUEOUS-SOLUTION
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11. Full Text O-Succinyl-l-homoserine-based C4-chemical production: succinic acid, homoserine lactone, γ-butyrolactone, γ-butyrolactone derivatives, and 1,4-butanediol
by Hong, Kuk-Ki and Kim, Jeong Hyun and Yoon, Jong Hyun and Park, Hye-Min and Choi, Su Jin and Song, Gyu Hyeon and Lee, Jea Chun and Yang, Young-Lyeol and Shin, Hyun Kwan and Kim, Ju Nam and Cho, Kyung Ho and Lee, Jung Ho
Journal of Industrial Microbiology & Biotechnology, ISSN 1367-5435, 10/2014, Volume 41, Issue 10, pp. 1517 - 1524
There has been a significant global interest to produce bulk chemicals from renewable resources using engineered microorganisms. Large research programs have... 
Biochemistry, general | Homoserine | Biotechnology | 1,4-Butanediol | Microbiology | γ-Butyrolactone derivatives | Homoserine lactone | Bio C4 chemicals | Life Sciences | Genetic Engineering | γ-Butyrolactone | Succinic acid | Inorganic Chemistry | Industrial biotechnology | Bioinformatics | O -Succinyl- l -homoserine | O-Succinyl- l-homoserine | O-Succinyl-l-homoserine | O-Succinyl-L-homoserine | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI | GENES | gamma-Butyrolactone | gamma-Butyrolactone derivatives | Hydrolysis | Bioreactors | Escherichia coli - genetics | Succinic Acid - metabolism | 4-Butyrolactone - biosynthesis | Escherichia coli - metabolism | Homoserine - biosynthesis | Solubility | 4-Butyrolactone - analogs & derivatives | Homoserine - analogs & derivatives | Fermentation | Butylene Glycols - metabolism
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12. Full Text Synthesis of linear and star poly(ε-caprolactone) with controlled and high molecular weights via cyclic trimeric phosphazene base catalyzed ring-opening polymerization
by Li, Huaike and Zhao, Na and Ren, Chuanli and Liu, Shaofeng and Li, Zhibo
Polymer Chemistry, ISSN 1759-9954, 2017, Volume 8, Issue 47, pp. 7369 - 7374
Poly(ε-caprolactones) (PCLs) with low catalyst loading and high molecular weights are highly desired considering their practical applications. In this work,... 
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13. Full Text Efficient catalysts for ring‐opening polymerization of ε‐caprolactone and β‐butyrolactone: Synthesis and characterization of zinc complexes based on benzotriazole phenoxide ligands
by Tai, Yu‐En and Li, Chen‐Yu and Lin, Chia‐Her and Liu, Yi‐Chang and Ko, Bao‐Tsan and Sun, Ya‐Sen
Journal of Polymer Science Part A: Polymer Chemistry, ISSN 0887-624X, 09/2011, Volume 49, Issue 18, pp. 4027 - 4036
A series of efficient zinc catalysts supported by sterically bulky benzotriazole phenoxide (BTP) ligands are synthesized and structurally characterized. The... 
benzotriazole phenoxide | β‐butyrolactone | ring‐opening polymerization | biodegradable | catalysts | living polymerization | ε‐caprolactone | zinc | polyesters | ε-caprolactone | β-butyrolactone | ring-opening polymerization | POLYMER SCIENCE | ALUMINUM COMPLEXES | ALKOXIDES | MAGNESIUM | LACTONES | epsilon-caprolactone | IMMORTAL POLYMERIZATION | LACTIDE | beta-butyrolactone | INITIATORS
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14. Full Text Stereoselective Synthesis of γ‐Butyrolactones Subunit of Polycavernoside A
by Kadari, Sudhakar and Yerrabelly, Hemasri and Gogula, Thirupathi and Erukala, Yadaiah Goud and Yerrabelly, Jayaprakash Rao and Begari, Prem Kumar
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 08/2018, Volume 55, Issue 8, pp. 1986 - 1990
An efficient and versatile linear synthesis of γ‐butyrolactone subunit of polycavernolide A has been reported in 14.2% overall yield with 10 linear steps by... 
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15. Full Text Establishing a novel biosynthetic pathway for the production of 3,4-dihydroxybutyric acid from xylose in Escherichia coli
by Wang, Jia and Wang, Jian and Shen, Xiaolin and Jain, Rachit and Yuan, Qipeng and Yan, Yajun
Metabolic Engineering, ISSN 1096-7176, 05/2017, Volume 41, pp. 39 - 45
3-Hydroxy-γ-butyrolactone (3HBL) is an attractive building block owing to its broad applications in pharmaceutical industry. Currently, 3HBL is commercially... 
Metabolic engineering | 3-hydroxy-γ-butyrolactone | Escherichia coli | Xylose metabolism | 4-dihydroxybutyric acid | 3-hydroxy-gamma-butyrolactone | K-12 | ALDEHYDE | CHEMICALS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | (S)-3-HYDROXY-GAMMA-BUTYROLACTONE | ENGINEERING NONPHOSPHORYLATIVE METABOLISM | DEHYDROGENASE | 4-Butyrolactone - genetics | 4-Butyrolactone - metabolism | Metabolic Engineering - methods | Xylose - metabolism | Escherichia coli - genetics | Escherichia coli - metabolism | 4-Butyrolactone - analogs & derivatives | Hydroxybutyrates - metabolism | Xylose - genetics | Glucose | Dextrose | Resveratrol | Yuan (China) | Lactones
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