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1. Full Text Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments
by Di Marco Barros, Rafael and Roberts, Natalie A and Dart, Robin J and Vantourout, Pierre and Jandke, Anett and Nussbaumer, Oliver and Deban, Livija and Cipolat, Sara and Hart, Rosie and Iannitto, Maria Luisa and Laing, Adam and Spencer-Dene, Bradley and East, Philip and Gibbons, Deena and Irving, Peter M and Pereira, Pablo and Steinhoff, Ulrich and Hayday, Adrian
Cell (Cambridge), ISSN 0092-8674, 09/2016, Volume 167, Issue 1, pp. 203 - 218.e17
Animals | Butyrophilins - immunology | Butyrophilins - genetics | Intestinal Mucosa - immunology | Humans | Mice, Inbred C57BL | Receptors, Antigen, T-Cell, gamma-delta - immunology | T-Lymphocytes - immunology | Thymus Gland - immunology | Mice | Gene Knockout Techniques | Index Medicus | Thymus Gland | Life Sciences | Intestinal Mucosa | Immunology | T-Lymphocytes | Butyrophilins | Receptors, Antigen, T-Cell, gamma-delta
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2. Full Text The juxtamembrane domain of butyrophilin BTN3A1 controls phosphoantigen-mediated activation of human Vγ9Vδ2 T cells
by Peigné, Cassie-Marie and Léger, Alexandra and Gesnel, Marie-Claude and Konczak, Fabienne and Olive, Daniel and Bonneville, Marc and Breathnach, Richard and Scotet, Emmanuel
The Journal of immunology (1950), ISSN 0022-1767, 06/2017, Volume 198, Issue 11, pp. 4228 - 4234
T-Lymphocyte Subsets - immunology | Antigens, CD - immunology | Phosphorylation | Butyrophilins - immunology | Lymphocyte Activation | Humans | Butyrophilins - chemistry | Receptors, Antigen, T-Cell, gamma-delta - immunology | Antigens - chemistry | Antigens, CD - metabolism | HEK293 Cells | Antigens - immunology | Butyrophilins - metabolism | Mutant Chimeric Proteins - immunology | Antigens, CD - chemistry | Butyrophilin | Cell activation | Metabolites | Lymphocytes | Tumor cells | Lymphocytes T | Dimerization | Index Medicus | Abridged Index Medicus | Life Sciences | Antigens | T-Lymphocyte Subsets | Immunology | Mutant Chimeric Proteins | Butyrophilins | Receptors, Antigen, T-Cell, gamma-delta | Antigens, CD
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3. Full Text Butyrophilin3A proteins and Vγ9Vδ2 T cell activation
by Gu, Siyi and Borowska, Marta T and Boughter, Christopher T and Adams, Erin J
Seminars in cell & developmental biology, ISSN 1084-9521, 12/2018, Volume 84, pp. 65 - 74
γδ T cells | Butyrophilins | Phosphoantigens | BTN3A | Vγ9Vδ2 T cells | Recognition mechanism | Antigens, CD - immunology | Diphosphates - pharmacology | Butyrophilins - immunology | Humans | Antigens, CD - drug effects | Lymphocyte Activation - immunology | Animals | Butyrophilins - pharmacology | Lymphocyte Activation - drug effects | T-Lymphocytes - drug effects | T-Lymphocytes - immunology | Phosphorylation - drug effects | Butyrophilins - drug effects | Index Medicus
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4. Full Text Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells
by Rigau, Marc and Ostrouska, Simone and Fulford, Thomas S and Johnson, Darryl N and Woods, Katherine and Ruan, Zheng and McWilliam, Hamish E G and Hudson, Christopher and Tutuka, Candani and Wheatley, Adam K and Kent, Stephen J and Villadangos, Jose A and Pal, Bhupinder and Kurts, Christian and Simmonds, Jason and Pelzing, Matthias and Nash, Andrew D and Hammet, Andrew and Verhagen, Anne M and Vairo, Gino and Maraskovsky, Eugene and Panousis, Con and Gherardin, Nicholas A and Cebon, Jonathan and Godfrey, Dale I and Behren, Andreas and Uldrich, Adam P
Science (American Association for the Advancement of Science), ISSN 0036-8075, 02/2020, Volume 367, Issue 6478, p. eaay5516
Antigens, CD - immunology | Phosphorylation | Butyrophilins - immunology | Antigens, Neoplasm - immunology | Butyrophilins - genetics | Lymphocyte Activation | Humans | Protein Multimerization | Butyrophilins - chemistry | Receptors, Antigen, T-Cell, gamma-delta - immunology | Cell Line, Tumor | Protein Domains | Ligands | T-Lymphocytes - immunology | Antigens, CD - chemistry | Butyrophilin | Pathogens | Antigens | Infectious diseases | Lymphocytes | Immunotherapy | T cell receptors | Lymphocytes T | Genomes | Binding sites | Immune system | Index Medicus
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5. Full Text The butyrophilin 3A1 intracellular domain undergoes a conformational change involving the juxtamembrane region
by Nguyen, Khiem and Li, Jin and Puthenveetil, Robbins and Lin, Xiaochen and Poe, Michael M and Christine Hsiao, Chia‐Hung and Vinogradova, Olga and Wiemer, Andrew J
The FASEB journal, ISSN 0892-6638, 11/2017, Volume 31, Issue 11, pp. 4697 - 4706
bisphosphonate | γ δ T cell | CD277 | B7 family coreceptor | phosphoantigen | Phosphoantigen | Bisphosphonate | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Organophosphates - metabolism | Butyrophilins - genetics | Humans | Butyrophilins - chemistry | Mutation, Missense | Antigens, CD - genetics | Antigens, CD - metabolism | X-Ray Diffraction | K562 Cells | Nuclear Magnetic Resonance, Biomolecular | Protein Domains | Butyrophilins - metabolism | Organophosphates - chemistry | Antigens, CD - chemistry | Amino Acid Substitution | Binding | Butyrophilin | Residues | Nuclear magnetic resonance--NMR | Lymphocytes T | Small angle X ray scattering | Mutants | Magnetic resonance spectroscopy | X-ray scattering | Cell activation | Lymphocytes | Zoledronic acid | Ligands | X ray scattering | Mutation | Diphosphates | Intracellular | NMR spectroscopy | Crystal structure | Index Medicus | Research
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6. Full Text Prediction of disordered regions and their roles in the anti-Pathogenic and immunomodulatory functions of butyrophilins
by Redwan, Elrashdy M and Al-Hejin, Ahmed M and Almehdar, Hussein A and Elsaway, Abdelrahman M and Uversky, Vladimir N
Molecules (Basel, Switzerland), ISSN 1420-3049, 2018, Volume 23, Issue 2, p. 328
Butyrophilin | Intrinsic disorder | Antigen presentation | Function | Immune response | Structure | Milk - chemistry | Antigen-Presenting Cells - cytology | Humans | Butyrophilins - chemistry | Intrinsically Disordered Proteins - classification | Butyrophilins - classification | Antigen Presentation | Killer Cells, Natural - immunology | Female | Intrinsically Disordered Proteins - immunology | Milk - immunology | Protein Interaction Domains and Motifs | Binding Sites | Protein Conformation, alpha-Helical | Gene Expression | Butyrophilins - immunology | Butyrophilins - genetics | Immunity, Innate | Antigen-Presenting Cells - immunology | Intrinsically Disordered Proteins - genetics | Protein Interaction Mapping | Killer Cells, Natural - cytology | Animals | Protein Conformation, beta-Strand | T-Lymphocytes - cytology | Intrinsically Disordered Proteins - chemistry | Protein Binding | T-Lymphocytes - immunology | Structural Homology, Protein | Proteins | Cell fate | Lactation | Immunomodulation | Globules | Lymphocytes T | Gene polymorphism | Cell surface | Polymorphism | Membrane proteins | Milk fat globule membranes | Index Medicus | antigen presentation | intrinsic disorder | immune response | structure | function | butyrophilin
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7. Full Text γδ T cells in homeostasis and host defence of epithelial barrier tissues
by Nielsen, Morten M and Witherden, Deborah A and Havran, Wendy L
Nature reviews. Immunology, ISSN 1474-1733, 12/2017, Volume 17, Issue 12, pp. 733 - 745
Intraepithelial Lymphocytes - metabolism | Intraepithelial Lymphocytes - cytology | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Signal Transduction | Butyrophilins - genetics | Humans | Gene Expression Regulation | Homeostasis | Receptors, Antigen, T-Cell, gamma-delta - genetics | Intestinal Mucosa - microbiology | Host-Pathogen Interactions - immunology | Mucosal-Associated Invariant T Cells - immunology | Intestinal Mucosa - physiology | Mucosal-Associated Invariant T Cells - metabolism | Animals | Host-Pathogen Interactions - genetics | Epithelium - microbiology | Biomarkers | Butyrophilins - metabolism | Cell Differentiation | Epithelium - physiology | Mucosal-Associated Invariant T Cells - cytology | Intraepithelial Lymphocytes - immunology | Index Medicus
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8. Full Text Butyrophilin 3A (BTN3A, CD277)‐specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation
by Starick, Lisa and Riano, Felipe and Karunakaran, Mohindar M and Kunzmann, Volker and Li, Jianqiang and Kreiss, Matthias and Amslinger, Sabine and Scotet, Emmanuel and Olive, Daniel and Libero, Gennaro and Herrmann, Thomas
European journal of immunology, ISSN 0014-2980, 06/2017, Volume 47, Issue 6, pp. 982 - 992
Butyrophilin | Phosphoantigen | T‐cell activation | T‐cell receptor | Human γδ T cells | T-cell receptor | T-cell activation | Antigens, CD - immunology | Cell Line | Animals | Butyrophilins - immunology | Lymphocyte Activation | Humans | HEK293 Cells | Receptors, Antigen, T-Cell, gamma-delta - immunology | T-Lymphocytes - immunology | Mice | Antibodies, Monoclonal - immunology | Cell culture | Stimulation | T cell receptors | Lymphocytes T | Mode of action | Deltas | Stimulators | Cell activation | Lymphocytes | Immunotherapy | Monoclonal antibodies | Physiology | Inhibition | Complementarity-determining region 3 | Cancer | Index Medicus | Life Sciences | T-Lymphocytes | Receptors, Antigen, T-Cell, gamma-delta | Butyrophilins | Antibodies, Monoclonal | Antigens, CD
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9. Full Text In vivo administration of recombinant BTNL2-Fc fusion protein ameliorates graft-versus-host disease in mice
by Cui, Cheng and Tian, Xiaohong and Lin, Yujun and Su, Min and Chen, Qingquan and Wang, Shao-Yuan and Lai, Laijun
Cellular immunology, ISSN 0008-8749, 01/2019, Volume 335, pp. 22 - 29
Graft-versus-host disease | Butyrophilin-like 2 | Activation | T cell proliferation | Regulatory T cells | Hematopoietic stem cell transplantation | Immunology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Recombinant Fusion Proteins - immunology | Butyrophilins - immunology | Recombinant Fusion Proteins - pharmacology | Lymphocyte Activation | Humans | Mice, Inbred C57BL | Graft vs Host Disease - metabolism | Th1 Cells - immunology | Transplantation, Homologous | T-Lymphocytes, Regulatory - immunology | Animals | Immunoglobulin Fc Fragments - immunology | Butyrophilins - pharmacology | Immunoglobulin G - immunology | Immunoglobulin G - pharmacology | Th17 Cells - immunology | Butyrophilins - metabolism | Graft vs Host Disease - prevention & control | Mice | Mice, Inbred BALB C | Hematopoietic Stem Cell Transplantation - methods | Yuan (China) | Transplantation | T cells | Hematopoietic stem cells | Stem cells | Index Medicus | regulatory T cells | hematopoietic stem cell transplantation | activation | graft-versus-host disease
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10. Full Text The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness
by Melandri, Daisy and Zlatareva, Iva and Chaleil, Raphaël A. G and Dart, Robin J and Chancellor, Andrew and Nussbaumer, Oliver and Polyakova, Oxana and Roberts, Natalie A and Wesch, Daniela and Kabelitz, Dieter and Irving, Peter M and John, Susan and Mansour, Salah and Bates, Paul A and Vantourout, Pierre and Hayday, Adrian C
Nature immunology, ISSN 1529-2908, 12/2018, Volume 19, Issue 12, pp. 1352 - 1365
Immunity, Innate - immunology | Lymphocyte Activation - immunology | Animals | Butyrophilins - immunology | Humans | Mice, Inbred C57BL | Antigens - immunology | Receptors, Antigen, T-Cell, gamma-delta - immunology | Mice | Adaptive Immunity - immunology | Butyrophilin | Antigens | Innate immunity | Chains | Adaptive immunity | Lymphocytes T | Gene expression | B7 antigen | Immunity | Proteins | T-cell receptor | Stimulators | Receptors | Lymphocytes | Coding | Compartments | Complementarity-determining region 1 | Complementarity-determining region 3 | Index Medicus
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11. Full Text Regulation of Immunity by Butyrophilins
by Rhodes, David A and Reith, Walter and Trowsdale, John
Annual review of immunology, ISSN 0732-0582, 5/2016, Volume 34, Issue 1, pp. 151 - 172
BTN2A | B30.2 | BTN3A | BTN1A | PRYSPRY | Adaptive Immunity | Butyrophilins - immunology | Receptors, Antigen, T-Cell - metabolism | Signal Transduction | Lymphocyte Activation | Humans | Immunity, Innate | Antigen-Presenting Cells - immunology | B7 Antigens - metabolism | Animals | Cattle | Milk - metabolism | Butyrophilins - metabolism | T-Lymphocytes - immunology | Mice | Milk proteins | Immune response | Major histocompatibility complex | Observations | Health aspects | Index Medicus
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