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PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e101552
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 03/2014, Volume 19, Issue 3, pp. 351 - 357
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 11/2016, Volume 259, Issue Pt B, pp. 271 - 275
Journal Article
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 11/2019, Volume 20, Issue 21, p. 5385
A set of 25 novel, silicon-based carbamate derivatives as potential acetyl- and butyrylcholinesterase (AChE/BChE) inhibitors was synthesized and characterized... 
VITRO | BUTYRYLCHOLINESTERASE | ANTIMYCOBACTERIAL | IN-SILICO | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | similarity-activity landscape index | silicon-based carbamates | IVE-PLS | CoMSA | CHEMISTRY, MULTIDISCIPLINARY | in vitro cholinesterase inhibition | molecular docking | ACETYLCHOLINESTERASE | BIOLOGICAL-ACTIVITY | PHOTOSYSTEM-II | SPECTRUM | BINDING | comsa | ive-pls
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 03/2019, Volume 83, pp. 277 - 288
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2016, Volume 124, pp. 270 - 283
Journal Article
Translational Oncology, ISSN 1936-5233, 08/2018, Volume 11, Issue 4, pp. 1012 - 1022
Butyrylcholinesterase (BChE) is a plasma enzyme that hydrolyzes ghrelin and bioactive esters, suggesting a role in modulating metabolism. Serum BChE is reduced... 
CHOLINESTERASE | SURVIVAL | TUMORS VARIES | INDEPENDENT PREDICTOR | PREOPERATIVE BUTYRYLCHOLINESTERASE | ONCOLOGY | GHRELIN | SENSITIVITY | SERUM | DRUG-RESISTANCE | LEVEL
Journal Article
Journal Article
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 09/2017, Volume 143, pp. 283 - 288
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2018, Volume 8, Issue 1, p. 16525
Pesticide exposure is associated with increased risk of Parkinson's disease (PD). We investigated in Egypt whether common variants in genes involved in... 
BUTYRYLCHOLINESTERASE | POPULATION | RISK-FACTORS | METAANALYSIS | MULTIDISCIPLINARY SCIENCES | TOXICITY | ASSOCIATION | SINGLE-NUCLEOTIDE POLYMORPHISMS | APPLICATORS
Journal Article
Journal of Asian Natural Products Research, ISSN 1028-6020, 11/2019, Volume 21, Issue 11, pp. 1090 - 1103
A series of new coumarin/1,2,4-oxadiazole hybrids were synthesized and evaluated for cholinesterase inhibitory and neuroprotective activities. Among them,... 
Coumarin/1,2,4-oxadiazole hybrids | Alzheimer's disease | butyrylcholinesterase inhibitor | neuroprotective activity | Alzheimer’s disease | Neuroprotection | Neurotoxicity | Hybrids | Neurodegenerative diseases | Bioassays | Selectivity | Enantiomers | Alzheimers disease | Coumarin | Cholinesterase
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 11/2011, Volume 67, Issue 11, pp. 1147 - 1157
Purpose Cholinesterase inhibitors are commonly prescribed to patients with Alzheimer's disease (AD) to enhance cholinergic neurotransmission. Differential... 
BCHE | cholinesterase inhibitors | CYP2D6 | Alzheimer | pharmacogenetics | RIVASTIGMINE | DEMENTIA | EFFICACY | APOE GENOTYPE | POLYMORPHISM | CLINICAL PHARMACOKINETICS | DONEPEZIL | THERAPY | PHARMACOLOGY & PHARMACY | GALANTAMINE | BUTYRYLCHOLINESTERASE-K-VARIANT | Indans - adverse effects | Cholinesterase Inhibitors - pharmacokinetics | Butyrylcholinesterase - genetics | Humans | Middle Aged | Galantamine - pharmacokinetics | Male | Phenylcarbamates - pharmacokinetics | Indans - therapeutic use | Genetic Variation | Rivastigmine | Aged, 80 and over | Female | Piperidines - pharmacokinetics | Indans - administration & dosage | Cytochrome P-450 CYP2D6 - genetics | Alzheimer Disease - physiopathology | Piperidines - administration & dosage | Genetic Association Studies | Phenylcarbamates - therapeutic use | Alzheimer Disease - drug therapy | Phenylcarbamates - adverse effects | Genotype | Treatment Outcome | Galantamine - administration & dosage | Alzheimer Disease - enzymology | Cognition - drug effects | Phenylcarbamates - administration & dosage | Cholinesterase Inhibitors - administration & dosage | Galantamine - therapeutic use | Piperidines - therapeutic use | Apolipoproteins E - genetics | Piperidines - adverse effects | Cholinesterase Inhibitors - adverse effects | Galantamine - adverse effects | Aged | Cholinesterase Inhibitors - therapeutic use | Indans - pharmacokinetics | Pharmacogenetics | Care and treatment | Gene mutations | Analysis | Cytochrome P-450 | Physiological aspects | Genetic research | Evolution | Genetic aspects | Apolipoproteins | Galanthamine | Alzheimer's disease | Enzymes | Pharmacology | Genetic diversity | Alzheimers disease | Clinical outcomes | Drugs | Pharmacodynamics | Activities of daily living | Neurodegenerative diseases | Cytochrome P450 | Cognitive ability | Metabolism | galantamine | Cholinesterase | Apolipoprotein E | Coding | donepezil | Pharmacokinetics | CYP2D6 protein | Genotypes | Neurotransmission
Journal Article