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LANCET NEUROLOGY, ISSN 1474-4422, 02/2008, Volume 7, Issue 2, pp. 129 - 135
Background Amyloid-beta (AP) plaque formation is a hallmark of Alzheimer's disease (AD) and precedes the onset of dementia. A beta imaging should allow earlier... 
C-11-PIB PET | DIAGNOSIS | POSITRON-EMISSION-TOMOGRAPHY | DEMENTIA | DEPOSITION | COGNITIVE IMPAIRMENT | PLAQUES | PREVALENCE | PITTSBURGH COMPOUND-B | BRAIN | CLINICAL NEUROLOGY
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 02/2016, Volume 57, Issue 2, pp. 208 - 214
Imaging of neurofibrillary pathology in the brain helps in diagnosing dementia, tracking disease progression, and evaluating the therapeutic efficacy of... 
DEMENTIA | tau | C-11-PIB | PLAQUES | FUTURE | PITTSBURGH COMPOUND-B | BETA | POSITRON-EMISSION-TOMOGRAPHY | radiotracer | F-18-THK5351 | TANGLES | Alzheimer's disease | DERIVATIVES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | PHF-TAU RADIOLIGAND
Journal Article
Annals of Neurology, ISSN 0364-5134, 10/2008, Volume 64, Issue 4, pp. 388 - 401
Objective Alzheimer's disease (AD) is found at autopsy in up to one third of patients with primary progressive aphasia (PPA), but clinical features that... 
C-11-PIB PET | ALZHEIMERS-DISEASE | SEMANTIC DEMENTIA | PATHOLOGY | HYPOMETABOLISM | FRONTOTEMPORAL LOBAR DEGENERATION | BINDING | NEUROSCIENCES | PITTSBURGH COMPOUND-B | BRAIN | CLINICAL NEUROLOGY | NONFLUENT APHASIA
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 10/2015, Volume 56, Issue 10, pp. 1547 - 1553
Alzheimer disease is the cause of up to one-third of cases of primary progressive aphasia or corticobasal syndrome. The primary objective of this study was to... 
FDG-PET | PET brain imaging | C-11-PIB PET | METAANALYSIS | Alzheimer disease | ALZHEIMERS-DISEASE | FRONTOTEMPORAL DEMENTIA | focal-onset dementias | C-11-PiB | MILD COGNITIVE IMPAIRMENT | DEGENERATION | POSITRON-EMISSION-TOMOGRAPHY | BRAIN PET | F-18-FDG | PRIMARY PROGRESSIVE APHASIA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 11/2018, Volume 59, Issue 11, pp. 1761 - 1767
Head motion occurring during brain PET studies leads to image blurring and to bias in measured local quantities. The objective of this work was to implement a... 
rigid motion correction | C-11-PIB | list-mode rebinner | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 2014, Volume 55, Issue 8, pp. 1305 - 1307
This study compared several parametric imaging methods to determine the optimal approach for visual assessment of parametric Pittsburgh compound-B (11C-PIB)... 
C-11-PIB PET | INTERNATIONAL WORKSHOP | ALZHEIMERS-DISEASE | FRONTOTEMPORAL DEMENTIA | C-11-PIB | visual assessment | positron emission tomography | DIAGNOSTIC-CRITERIA | Alzheimer's disease | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PROGRESSIVE SUPRANUCLEAR PALSY | DEGENERATION
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 05/2009, Volume 50, Issue 5, pp. 818 - 822
We have characterized the biodistribution and dosimetry of F-18-3'-F-6-OH-BTA1 (F-18-GE067), a newly developed radioligand to visualize and quantify amyloid... 
F-18-BAY94-9172 | DIAGNOSIS | biodistribution | dosimetry | healthy subjects | ALZHEIMERS-DISEASE | C-11-PIB | PLAQUES | BETA | AGENT | F-18-GE067 | amyloid imaging | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
Current Alzheimer Research, ISSN 1567-2050, 01/2010, Volume 7, Issue 1, pp. 56 - 66
Background: New in vivo amyloid PET imaging tracers, such as C-11-PIB, provide possibilities to deeper understand the underlying pathological processes in... 
C-PIB-PET | MCI | Amyloid | Cognition | F-FDG-PET | CSF biomarkers | C-11-PIB PET | F-18-FDG-PET | cognition | PET AMYLOID LIGAND | MILD COGNITIVE IMPAIRMENT | CEREBROSPINAL-FLUID | NEUROSCIENCES | PITTSBURGH COMPOUND-B | CLINICAL NEUROLOGY | C-11-PIB-PET | POSITRON-EMISSION-TOMOGRAPHY | PHOSPHORYLATED-TAU | GLUCOSE-METABOLISM | NONDEMENTED INDIVIDUALS | PARKINSONS-DISEASE
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 08/2011, Volume 52, Issue 8, pp. 1210 - 1217
Journal Article
ANNALS OF NEUROLOGY, ISSN 0364-5134, 06/2013, Volume 73, Issue 6, pp. 751 - 761
ObjectiveThis study examined amyloid- (A) deposition in 190 nondemented subjects aged 82 years to determine the proportion of A-positive scans and associations... 
DIAGNOSIS | DEMENTIA | ALZHEIMERS-DISEASE | GINKGO-BILOBA | OLDER-ADULTS | PIB | C-11-PIB | NEUROPATHOLOGY | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | PET | CLINICAL NEUROLOGY | Deposition | Medical imaging
Journal Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, ISSN 1619-7070, 07/2018, Volume 45, Issue 7, pp. 1129 - 1138
Purpose F-18-Florbetapir has been reported to show cardiac uptake in patients with systemic light-chain amyloidosis (AL). This study systematically assessed... 
VISUALIZATION | DIAGNOSIS | Florbetapir | MANAGEMENT | SCINTIGRAPHY | INVOLVEMENT | C-11-PIB | CARDIAC AMYLOIDOSIS | Cardiac amyloid | TTR | Amyloid | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 04/2019, Volume 60, Issue 4, pp. 541 - 547
Our objective was to determine the optimal approach for assessing amyloid disease in a cognitively normal elderly population. Methods: Dynamic... 
amyloid pathology | DIAGNOSIS | TRIALS | HUMAN BRAIN | DEMENTIA | MRI | ALZHEIMERS-DISEASE | VALIDATION | F-18-flutemetamol PET | C-11-PIB | visual assessment | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | preclinical Alzheimer disease
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 10/2018, Volume 59, Issue 10, pp. 1583 - 1589
Amyloid-beta (A beta) deposition as seen on PET using an A beta-binding agent is a critical diagnostic biomarker for Alzheimer disease (AD). Some reports... 
DIAGNOSIS | HYPERINTENSITIES | ALZHEIMERS-DISEASE | PIB-PET | VALIDATION | C-11-PiB | MILD COGNITIVE IMPAIRMENT | amyloid-beta | white matter | POSITRON-EMISSION-TOMOGRAPHY | RECOMMENDATIONS | PERFUSION | BINDING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
Lancet Neurology, The, ISSN 1474-4422, 2011, Volume 10, Issue 7, pp. 667 - 670
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 09/2009, Volume 50, Issue 9, pp. 1464 - 1470
The purpose of this study was to investigate the potential relationships between cerebrospinal fluid (CSF) measurements of beta-amyloid-1-42 (A beta(1-42)) and... 
Pittsburgh compound B | tau | C-11-PiB | MILD COGNITIVE IMPAIRMENT | Alzheimer | PITTSBURGH COMPOUND-B | SENILE PLAQUES | BETA | CSF | INCIPIENT ALZHEIMERS-DISEASE | CEREBELLUM | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | F-18-FDDNP | BRAIN
Journal Article
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