X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (44) 44
c-abl oncogene (26) 26
leukemia, myelogenous, chronic, bcr-abl positive - genetics (22) 22
chronic myelogenous leukemia (18) 18
oncology (15) 15
acute lymphoblastic-leukemia (13) 13
chronic myeloid-leukemia (13) 13
hematology (13) 13
fusion proteins, bcr-abl - genetics (12) 12
leukemia, myelogenous, chronic, bcr-abl positive - pathology (12) 12
philadelphia chromosome (12) 12
female (10) 10
male (10) 10
middle aged (10) 10
adult (9) 9
bcr (9) 9
chronic myelocytic-leukemia (9) 9
bcr-abl (7) 7
blast crisis (7) 7
c-abl-oncogene (7) 7
leukemia, myelogenous, chronic, bcr-abl positive - drug therapy (7) 7
gene rearrangement (6) 6
mutation (6) 6
philadelphia-chromosome (6) 6
precursor cell lymphoblastic leukemia-lymphoma - genetics (6) 6
proto-oncogene proteins c-bcr - genetics (6) 6
translocation, genetic (6) 6
bcr gene (5) 5
benzamides (5) 5
cml (5) 5
gene expression regulation, neoplastic (5) 5
genetics & heredity (5) 5
imatinib mesylate (5) 5
leukemia, myelogenous, chronic, bcr-abl positive - diagnosis (5) 5
medicine, research & experimental (5) 5
prognosis (5) 5
rna, messenger - genetics (5) 5
translocation (5) 5
tyrosine kinase inhibitor (5) 5
acute lymphocytic-leukemia (4) 4
adolescent (4) 4
aged (4) 4
antineoplastic agents - therapeutic use (4) 4
biochemistry & molecular biology (4) 4
cells (4) 4
child (4) 4
chromosome aberrations (4) 4
chronic granulocytic-leukemia (4) 4
chronic myelocytic leukemia (4) 4
chronic myeloid leukemia (4) 4
gene (4) 4
index medicus (4) 4
leukemia (4) 4
oncogenes (4) 4
philadelphia translocation (4) 4
polymerase chain reaction (4) 4
protein kinase inhibitors - therapeutic use (4) 4
protein-tyrosine kinases - antagonists & inhibitors (4) 4
proto-oncogene proteins c-abl - genetics (4) 4
pyrimidines - therapeutic use (4) 4
remission induction (4) 4
research (4) 4
tumor cells, cultured (4) 4
acute myeloid-leukemia (3) 3
cancer (3) 3
care and treatment (3) 3
cell biology (3) 3
chromosome (3) 3
chromosome deletion (3) 3
fusion proteins, bcr-abl - biosynthesis (3) 3
genes, abl (3) 3
genes, abl - genetics (3) 3
genetic aspects (3) 3
hemic and lymphatic diseases (3) 3
in situ hybridization, fluorescence (3) 3
in-situ hybridization (3) 3
interferon-alpha - pharmacology (3) 3
karyotyping (3) 3
leukemia - genetics (3) 3
leukemia, myelogenous, chronic, bcr-abl positive - immunology (3) 3
leukemia, myelogenous, chronic, bcr-abl positive - metabolism (3) 3
leukemia, myeloid - genetics (3) 3
piperazines - therapeutic use (3) 3
protein-tyrosine kinases (3) 3
proto-oncogene proteins - genetics (3) 3
proto-oncogene proteins c-bcr (3) 3
proto-oncogene proteins c-myc - genetics (3) 3
rearrangement (3) 3
rna, messenger - metabolism (3) 3
transcription, genetic (3) 3
altered transcription (2) 2
antineoplastic agents - pharmacology (2) 2
antineoplastic combined chemotherapy protocols - therapeutic use (2) 2
apoptosis - drug effects (2) 2
bcr/abl (2) 2
blast crisis - genetics (2) 2
blast crisis - physiopathology (2) 2
blotting, northern (2) 2
blotting, southern (2) 2
bone marrow cells - pathology (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2009, Volume 119, Issue 10, pp. 2863 - 2865
When Brian J. Druker was a boy, he wanted to be a baseball player; Nicholas B. Lydon had his sights set on flying jets; Charles L. Sawyers knew early on that... 
CHRONIC MYELOGENOUS LEUKEMIA | C-ABL-ONCOGENE | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | CHRONIC GRANULOCYTIC LEUKEMIA | PHILADELPHIA-CHROMOSOME | BCR-ABL | BLAST CRISIS | RESISTANCE | TYROSINE KINASE INHIBITOR | CHRONIC MYELOID-LEUKEMIA | Oncologists | Care and treatment | Chronic myeloid leukemia | Innovations | Achievements and awards | Cancer
Journal Article
Journal Article
Anti-Cancer Drugs, ISSN 0959-4973, 1994, Volume 5, Issue 2, pp. 213 - 222
We have examined a series of tyrosine kinase inhibitors structurally related to erbstatin (tyrphostins) for inhibition of p210(bcr-abl) autokinase activity in... 
bcr-abl | chronic myelogenous leukemia | tyrosine kinase | CHRONIC MYELOGENOUS LEUKEMIA | C-ABL-ONCOGENE | BCR | CELLS | TRANSLOCATION | ONCOLOGY | TYROSINE KINASE | BCR-ABL | TYROSINE KINASE INHIBITOR | TRANSDUCTION | PHARMACOLOGY & PHARMACY | PROTEINS
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 07/1999, Volume 18, Issue 13, pp. 3564 - 3574
The MLL gene from human chromosome 11q23 is involved in >30 different chromosomal translocations resulting in a plethora of different MLL fusion proteins. Each... 
MLL GENE | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | chromosomal translocations | C-ABL ONCOGENE | haematopoiesis | HRX | RNA-BINDING PROTEIN | CELL BIOLOGY | 11Q23 CHROMOSOMAL TRANSLOCATIONS | ALL-1 | DROSOPHILA-TRITHORAX | MYXOID LIPOSARCOMA | ACUTE LYMPHOBLASTIC-LEUKEMIA | leukaemia | ALL-1 GENE | PROLINE-RICH PROTEIN
Journal Article