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NATURE, ISSN 0028-0836, 03/2011, Volume 471, Issue 7338, pp. 363 - 363
Caspase-8 has two opposing biological functions-it promotes cell death by triggering the extrinsic pathway of apoptosis, but also has a survival activity, as... 
RIP1 KINASE | APOPTOSIS | ACTIVATION | HOMEOSTASIS | SPECIFICITY | MULTIDISCIPLINARY SCIENCES | C-FLIP | RECEPTOR | CELL-DEATH | TRANSGENIC MICE | REQUIREMENT
Journal Article
Cell Death and Disease, 2014, Volume 5, Issue 4
Journal Article
by Ge, R and Wang, Z and Zeng, Q and Xu, X and Olumi, A.F
Cell Death and Differentiation, ISSN 1350-9047, 07/2011, Volume 18, Issue 7, pp. 1184 - 1195
Journal Article
IUBMB Life, ISSN 1521-6543, 06/2013, Volume 65, Issue 6, pp. 533 - 543
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2015, Volume 16, Issue 6, pp. 2251 - 2256
Journal Article
Zhonghua wei zhong bing ji jiu yi xue, ISSN 2095-4352, 12/2018, Volume 30, Issue 12, pp. 1132 - 1136
Journal Article
Critical Reviews in Oncogenesis, ISSN 0893-9675, 2019, Volume 24, Issue 1, pp. 99 - 104
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 4/2015, Volume 194, Issue 7, pp. 3444 - 3451
Apoptosis can be induced by either death receptors on the plasma membrane (extrinsic pathway), or the damage of the genome and/or cellular organelles... 
T lymphocytes | autophagy | intrinsic apoptosis | c-FLIP | Bim
Journal Article
Cell, ISSN 0092-8674, 05/2014, Volume 157, Issue 5, pp. 1175 - 1188
Journal Article
Journal Article
Asian Pacific journal of cancer prevention : APJCP, ISSN 1513-7368, 09/2017, Volume 18, Issue 9, pp. 2493 - 2499
Background: Mycosis fungoides (MF) is the commonest variant of primary cutaneous T cell lymphoma with several clinicopathologic variants. Defective apoptotic... 
pathogenesis | c-FLIP protein | mycosis fungoides
Journal Article
by Lee, SR and Quan, KT and Byun, HS and Park, I and Kang, K and Piao, X and Ju, E and Ro, H and Na, M and Hur, GM
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9
Plant-derived lignans have numerous biological effects including anti-tumor and anti-inflammatory activities. Screening of purified constituents of Rubia... 
CANCER-CELLS | SURVIVIN | MULTIDISCIPLINARY SCIENCES | C-FLIP | RESISTANCE | RECEPTOR | CASPASE-8 | DEATH | NF-KAPPA-B | EXPRESSION | P-GLYCOPROTEIN
Journal Article
PLOS ONE, ISSN 1932-6203, 02/2018, Volume 13, Issue 2
Evidence has shown that most hepatocellular carcinoma (HCC) cells are resistant to tumor necrosis factor (TNF)-related apoptosis-inducing ligand... 
HEPATOCELLULAR-CARCINOMA CELLS | INHIBITION | DECOY RECEPTOR | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | C-FLIP | MONOCYTES | DEATH | LIGAND | CANCER | MODULATION
Journal Article
Blood, ISSN 0006-4971, 08/2005, Volume 106, Issue 4, pp. 1392 - 1399
Primary mediastinal large B-cell lymphoma (MLBCL) shares important clinical and molecular features with classic Hodgkin lymphoma, including nuclear... 
AMPLIFICATION | INDUCED APOPTOSIS | C-FLIP | ALPHA | CLASSICAL HODGKIN LYMPHOMA | HLA-F | HEMATOLOGY | EXPRESSION | STERNBERG CELLS | REL GENE | T-CELLS
Journal Article
Anticancer research, ISSN 0250-7005, 10/2018, Volume 38, Issue 10, pp. 5709 - 5716
Background/Aim: In the present study, the antineoplastic activity and mechanism of action of phenoxodiol, a novel isoflavone analog, was investigated in renal... 
renal cancer | Akt | Phenoxodiol | c-FLIP | APOPTOSIS | PROTEIN | SENSITIVITY | FLAVONOIDS | IDENTIFICATION | INHIBITION | CISPLATIN | ONCOLOGY | OVARIAN | CARCINOMA
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2019, Volume 512, Issue 1, pp. 60 - 65
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has received attention as an anticancer therapy because it mediates apoptosis of several cancer... 
Genome editing | Tumor necrosis factor-related apoptosis-inducing ligand | cFLIP | Anticancer therapy | DR5 | ACTIVATION | INHIBITORY PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | CANCER | BIOPHYSICS | PATHWAY | C-FLIP | EXPRESSION
Journal Article
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, ISSN 1044-1549, 01/2018, Volume 58, Issue 1, pp. 66 - 78
Idiopathic pulmonary fibrosis is a progressive lung disease with complex pathophysiology and fatal prognosis. Macrophages (M Phi) contribute to the development... 
RESIDENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOCYTES | INJURY | macrophage | CELL BIOLOGY | CELL SUBSETS | RNA-seq | MURINE LUNG | RESPIRATORY SYSTEM | ALVEOLAR MACROPHAGES | TISSUE MACROPHAGES | fibrosis | STEADY-STATE | IDIOPATHIC PULMONARY-FIBROSIS | c-FLIP | IPF | MONONUCLEAR PHAGOCYTES
Journal Article
MOLECULAR CANCER RESEARCH, ISSN 1541-7786, 05/2019, Volume 17, Issue 5, pp. 1102 - 1114
The high incidence of glioblastoma recurrence necessitates additional therapeutic strategies. Heterogeneous populations of cells, including glioma stem cells... 
APOPTOSIS-INDUCING LIGAND | CANCER CELLS | ONCOLOGY | DR5 EXPRESSION | KINASE | DOWN-REGULATION | C-FLIP | MELANOMA-CELLS | ACTIVATING TRANSCRIPTION FACTOR-3 | UP-REGULATION | ADJUVANT TEMOZOLOMIDE | CELL BIOLOGY
Journal Article
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