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chemistry, organic (52) 52
chemistry, multidisciplinary (29) 29
c-h difluoroalkylation (27) 27
catalysis (26) 26
difluoroalkylation (26) 26
c-h functionalization (20) 20
photoredox catalysis (19) 19
alkenes (18) 18
fluorine (18) 18
hydrazones (18) 18
derivatives (16) 16
functionalized difluoromethyl bromides (16) 16
heteroarenes (15) 15
light photoredox catalysis (14) 14
trifluoromethylation (14) 14
aryl boronic acids (13) 13
functional groups (13) 13
organic chemistry (13) 13
chemistry, applied (11) 11
functionalization (11) 11
carboxylic-acids (10) 10
copper (10) 10
palladium (10) 10
perfluoroalkylation (10) 10
radicals (10) 10
synthesis (10) 10
c-h bonds (9) 9
ethyl bromodifluoroacetate (9) 9
medicinal chemistry (9) 9
metal-free (9) 9
alkylation (8) 8
aromatic compounds (8) 8
chemical synthesis (8) 8
chemistry (8) 8
cyclization (8) 8
difluoromethylation (8) 8
fluorination (8) 8
n,n-dialkylhydrazones (8) 8
reagents (8) 8
alpha,beta-unsaturated carboxylic-acids (7) 7
arenes (7) 7
copper-mediated difluoromethylation (7) 7
functionalisation (7) 7
funktionalisierung (7) 7
heterocycles (7) 7
photocatalysis (7) 7
substrates (7) 7
visible light (7) 7
access (6) 6
acids (6) 6
aldehydes (6) 6
alkynes (6) 6
arylboronic acids (6) 6
catalysts (6) 6
copper-catalyzed trifluoromethylation (6) 6
difluoroacetylation (6) 6
fluoroalkylation (6) 6
functional-group (6) 6
funktionelle gruppe (6) 6
organic-synthesis (6) 6
synthetic methods (6) 6
unactivated alkenes (6) 6
activation (5) 5
aryl (5) 5
bonding (5) 5
bromides (5) 5
c-h activation (5) 5
c-h difluoromethylation (5) 5
c−h functionalization (5) 5
photoredox (5) 5
radical reactions (5) 5
reaction-mechanism (5) 5
reaktionsmechanismus (5) 5
regioselectivity (5) 5
aldehyde-derived hydrazones (4) 4
c-h trifluoromethylation (4) 4
chemistry, physical (4) 4
cyclisation (4) 4
electron-rich heteroarenes (4) 4
fluor (4) 4
fluoroalkylation reactions (4) 4
imines (4) 4
index medicus (4) 4
inhibitors (4) 4
ketones (4) 4
kupfer (4) 4
light (4) 4
light irradiation (4) 4
oxidative trifluoromethylation (4) 4
photochemistry (4) 4
radical trifluoromethylation (4) 4
radical-addition (4) 4
room-temperature (4) 4
selectivity (4) 4
strategy (4) 4
transfer radical-addition (4) 4
visible-light (4) 4
alpha,alpha-difluoroarylacetic acids (3) 3
alpha-arylation (3) 3
article (3) 3
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Angewandte Chemie International Edition, ISSN 1433-7851, 02/2016, Volume 55, Issue 8, pp. 2934 - 2938
The first gold‐catalyzed photoredox C(sp2)−H difluoroalkylation and perfluoroalkylation of hydrazones with readily available RF−Br reagents is reported. The... 
C−H functionalization | gold catalysis | photocatalysis | fluorine | C-H functionalization | PALLADIUM | VISIBLE-LIGHT PHOTOREDOX | FLUOROALKYLATION | CHEMISTRY, MULTIDISCIPLINARY | C-H BONDS | FUNCTIONALIZATION | ALKENES | DIFLUOROMETHYLATION | ARYL BORONIC ACIDS | GEM-DIFLUOROALLYLATION | Phosphonates | Fluorides | Catalysis | Coupling (molecular) | Gold | Trapping | Reagents | Phosphonic acids | Hydrazones | Amino acids | Derivatives
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 09/2014, Volume 356, Issue 13, pp. 2741 - 2748
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 05/2016, Volume 81, Issue 9, pp. 3654 - 3664
An efficient and general method for C­(sp2)–H difluoroalkylation of aldehyde derived hydrazones via a CuII/B2pin2-catalyzed reaction between difluoroalkyl... 
PHARMACEUTICALS | ALPHA-ARYLATION | ALKYLATION | PROGRESS | CHEMISTRY, ORGANIC | FLUORINE | C-H DIFLUOROALKYLATION | ALPHA,ALPHA-DIFLUOROKETONES | RADICAL-ADDITION | BROMIDES | TRIFLUOROMETHYLATION
Journal Article
Organic Chemistry Frontiers, ISSN 2052-4110, 09/2016, Volume 3, Issue 9, pp. 1163 - 1185
Recent advances in photoinduced trifluoromethylation and difluoroalkylation under photocatalysis are summarized. Most of the photoredox reactions proceed... 
VISIBLE-LIGHT | ALPHA,BETA-UNSATURATED CARBOXYLIC-ACIDS | RADICAL CYCLIZATION | N-ARYLACRYLAMIDES | LIGHT PHOTOREDOX CATALYSIS | CHEMISTRY, ORGANIC | FLUORINATED 3,3-DISUBSTITUTED 2-OXINDOLES | FUNCTIONAL-GROUPS | ELECTRON-DEFICIENT ALKENES | ENANTIOSELECTIVE ALPHA-TRIFLUOROMETHYLATION | C-H TRIFLUOROMETHYLATION
Journal Article
Chemistry – An Asian Journal, ISSN 1861-4728, 09/2018, Volume 13, Issue 17, pp. 2516 - 2521
Regioselective C(2)−H difluoroalkylation of C‐3 unsubstituted indoles with commonly available fluoroalkyl bromides is successfully achieved employing a simple... 
nickel | indoles | fluoroalkylation | regioselective | ROOM-TEMPERATURE | C-H TRIFLUOROETHYLATION | COPPER-MEDIATED DIFLUOROMETHYLATION | OXIDATIVE TRIFLUOROMETHYLATION | ELECTRON-RICH HETEROARENES | CHEMISTRY, MULTIDISCIPLINARY | ARYLBORONIC ACIDS | ALKYL-HALIDES | ARYL BORONIC ACIDS | LIGHT PHOTOREDOX CATALYSIS | FUNCTIONALIZED DIFLUOROMETHYL BROMIDES | Nickel
Journal Article
Chemical Communications, ISSN 1359-7345, 2017, Volume 53, Issue 68, pp. 9482 - 9485
An unprecedented Rh-catalyzed C2-difluoroalkylation of indole derivatives with 2,2-difluorovinyl arenesulfonates has been reported. This reaction provides a... 
MEDICINAL CHEMISTRY | FUNCTIONALIZATION | NUCLEOPHILIC FLUORINATION | HETEROARENES | DIRECT ADDITION | ALKYNES | C-H ACTIVATION | CHEMISTRY, MULTIDISCIPLINARY | ARYLBORONIC ACIDS | CYCLIZATION | TRIFLUOROMETHYLATION
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 12/2017, Volume 2017, Issue 46, pp. 6947 - 6950
A ruthenium‐catalyzed highly selective difluoromethylation of 8‐aminoquinoline amides at the C5 position has been developed. It tolerates a broad range of... 
Fluorinated Compounds | Synthetic methods | Ruthenium | Fluorine | Homogeneous catalysis | DIRECTING GROUP | HALIDES | SULFONYLATION | COPPER-MEDIATED DIFLUOROMETHYLATION | ARENES | QUINOLINES | CHEMISTRY, ORGANIC | C-H FUNCTIONALIZATION | IODIDES | ARYL BORONIC ACIDS | CHLORIDES | Amides
Journal Article
Angewandte Chemie, ISSN 0044-8249, 01/2015, Volume 127, Issue 5, pp. 1666 - 1670
The synthesis of 3,3‐difluoro‐2‐oxindoles through a robust and efficient palladium‐catalyzed CH difluoroalkylation is described. This process generates a... 
Kreuzkupplungen | Heterocyclen | Palladium | C‐H‐Aktivierung | Fluor | Anti-Bacterial Agents - chemical synthesis | Anti-Bacterial Agents - chemistry | Indoles - chemical synthesis | Catalysis | Hydrogen - chemistry | Indoles - chemistry | Palladium - chemistry | Alkylation | Carbon - chemistry | Fluorine - chemistry | Ligands | Synthesis
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 09/2018, Volume 83, Issue 18, pp. 11377 - 11384
A convenient method for the preparation of sp3-rich heterocycles is reported. The method comprises a photocatalytic difluoroalkylation-induced 1,2-heteroarene... 
Journal Article | PLATFORM | KETONES | HETEROARENES | MICROREACTORS | OPERATION | CHEMISTRY | CHEMISTRY, ORGANIC | PHOTOCHEMISTRY | C-H FUNCTIONALIZATION | ESCAPE | PHOTOREDOX CATALYSIS | Note
Journal Article
Organic Letters, ISSN 1523-7060, 01/2018, Volume 20, Issue 1, pp. 190 - 193
A selective oxy-difluoroalkylation of allylamines with carbon dioxide (CO2) via visible-light photoredox catalysis is reported. These multicomponent reactions... 
ORGANIC-SYNTHESIS | C(SP)-H BONDS | NICKEL CATALYSIS | UNSATURATED-HYDROCARBONS | CHEMISTRY, ORGANIC | PHOTOCATALYTIC CARBOXYLATION | CARBON-DIOXIDE | MOLECULE SYNTHESIS | C-H BONDS | TRANSITION-METAL-FREE | DRIVEN CARBOXYLATION
Journal Article
Organic Chemistry Frontiers, ISSN 2052-4110, 2018, Volume 5, Issue 5, pp. 797 - 800
Visible-light-mediated tandem radical difluoroalkylation and alkynylation of unactivated alkenes is described in this communication. The process comprises a... 
PALLADIUM-CATALYZED DIFLUOROALKYLATION | VISIBLE-LIGHT | HETEROARENES | ARYL BORONIC ACIDS | PHENANTHRIDINE DERIVATIVES | ARENES | CHEMISTRY, ORGANIC | C-H DIFLUOROALKYLATION | ALPHA,ALPHA-DIFLUOROARYLACETIC ACIDS | ACCESS | CARBOXYLIC-ACIDS | Alkenes | Ketones | Access routes | Migration
Journal Article
by Liu, WQ and Chen, WH and Li, XX and Tang, WK and Tao, TT and Feng, YS
HETEROCYCLES, ISSN 0385-5414, 04/2019, Volume 98, Issue 4, pp. 570 - 581
A Eosin Y-catalyzed C(sp(2))-H difluoromethylation of aldehyde-derived hydrazones between difluoroalkyl bromides and aldehyde-derived hydrazones is reported.... 
ORGANIC-DYE | HETEROARENES | EOSIN Y | CHEMISTRY, ORGANIC | FLUORINE | C-H DIFLUOROALKYLATION | PHOTOREDOX CATALYSIS
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2017, Volume 56, Issue 7, pp. 1898 - 1902
Journal Article